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Journal of the Royal College of Physicians of Edinburgh最新文献

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Plasma exchange for the management of digoxin toxicity in an individual with an acute kidney injury: A case report. 血浆置换治疗急性肾损伤患者的地高辛中毒：病例报告。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-03-18 DOI: 10.1177/14782715241239372
Hannah Preston, Emma Cannon, Simon Watson
{"title":"Plasma exchange for the management of digoxin toxicity in an individual with an acute kidney injury: A case report.","authors":"Hannah Preston, Emma Cannon, Simon Watson","doi":"10.1177/14782715241239372","DOIUrl":"10.1177/14782715241239372","url":null,"abstract":"<p><p>Digoxin toxicity can be life-threatening. Digoxin-specific antibody (DSA) fragments are used in severe digoxin toxicity, binding to serum-free digoxin and enabling increased renal excretion. In severe renal impairment, clearance of these complexes is prolonged, leading to rebound toxicity. Digoxin and DSA complexes are not dialysable. We present a case of a gentleman with severe digoxin toxicity and acute kidney injury (AKI). Despite receiving DSA doses, his digoxin levels rebounded and symptoms persisted. Based on published case reports, plasma exchange (PEX) after further dosing was arranged. PEX facilitated the removal of digoxin-DSA complexes, bypassing renal excretion. During PEX, clinical signs improved and were sustained. He did not require further dialysis or PEX, renal function recovered and he was discharged. This case highlights challenges in the management of severe digoxin toxicity in patients with a concurrent AKI. The use of PEX enabled digoxin-DSA complex removal and should be considered in these circumstances.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Russel's sign: Unilateral hand callosities in bulimia nervosa. 罗素征神经性贪食症患者的单侧手部胼胝。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-01-29 DOI: 10.1177/14782715241228325
Verma Vaishnavi, Sharma Ritu, Bhari Neetu
{"title":"Russel's sign: Unilateral hand callosities in bulimia nervosa.","authors":"Verma Vaishnavi, Sharma Ritu, Bhari Neetu","doi":"10.1177/14782715241228325","DOIUrl":"10.1177/14782715241228325","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifocal presentation of cutaneous tuberculosis in a HIV positive patient. 一名 HIV 阳性患者的多灶性皮肤结核病。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-03-08 DOI: 10.1177/14782715241238784
Preeyati Chopra, Sharang Gupta, Dimple Chopra
{"title":"Multifocal presentation of cutaneous tuberculosis in a HIV positive patient.","authors":"Preeyati Chopra, Sharang Gupta, Dimple Chopra","doi":"10.1177/14782715241238784","DOIUrl":"10.1177/14782715241238784","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of early intraventricular haemorrhage following ventriculoperitoneal shunt: An entity requiring consideration. 一例脑室腹腔分流术后早期脑室内出血：一个需要考虑的实体。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-03-10 DOI: 10.1177/14782715241237579
Himanshu Kaushal, Madhugandha Wahane, Gourav Goyal, Sudha Sarna, Mukesh Kumar Sarna
{"title":"A case of early intraventricular haemorrhage following ventriculoperitoneal shunt: An entity requiring consideration.","authors":"Himanshu Kaushal, Madhugandha Wahane, Gourav Goyal, Sudha Sarna, Mukesh Kumar Sarna","doi":"10.1177/14782715241237579","DOIUrl":"10.1177/14782715241237579","url":null,"abstract":"<p><p>The ventriculoperitoneal shunt (VP shunt) is one of the most common neurosurgical procedures performed in daily practice. Various complications following a VP shunt are as follows: post-procedure shunt-related infections, shunt block, shunt displacement or exteriorisation and haemorrhage associated with it. Delayed intraventricular haemorrhage is a relatively uncommon complication following the aforementioned procedure. Here we present an atypical case of a 72-year-old male who presented with subarachnoid haemorrhage with hydrocephalus and underwent a VP shunt, following which the patient had early intraventricular haemorrhage (eIVH) with an unfortunate outcome. Here, we propose pathophysiology and risk factors for eIVH.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote and Rural Remedies exhibition. 偏远地区和农村补救措施展览。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 DOI: 10.1177/14782715241242191
{"title":"Remote and Rural Remedies exhibition.","authors":"","doi":"10.1177/14782715241242191","DOIUrl":"10.1177/14782715241242191","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hoffmann's syndrome in subclinical hypothyroidism. 亚临床甲状腺功能减退症的霍夫曼综合征
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2023-12-11 DOI: 10.1177/14782715231218033
Kiran Hs, Shashank Cheemalapati, Venkatesh Cr
{"title":"Hoffmann's syndrome in subclinical hypothyroidism.","authors":"Kiran Hs, Shashank Cheemalapati, Venkatesh Cr","doi":"10.1177/14782715231218033","DOIUrl":"10.1177/14782715231218033","url":null,"abstract":"<p><p>Hypothyroidism is an endocrine disorder which occurs due to a deficiency of thyroid hormones. Hoffmann's syndrome is a rare complication of hypothyroidism - presenting as hypothyroid myopathy. We describe the case of a 20-year-old lactating female, known to have hypothyroidism (diagnosed during her pregnancy and having discontinued treatment following delivery), presenting with complaints of pain, swelling of bilateral calf muscles with cramps in bilateral lower limbs. Symptoms of muscle pseudohypertrophy with muscle stiffness are relatively rare in subclinical hypothyroidism and it is important to identify and diagnose this rare condition, and initiate appropriate treatment.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physician-led thoracic ultrasound-guided biopsy; a district general hospital perspective. 医生主导的胸部超声引导活检；地区综合医院的视角。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-02-20 DOI: 10.1177/14782715241231331
M J Cafferkey, G A Martin
{"title":"Physician-led thoracic ultrasound-guided biopsy; a district general hospital perspective.","authors":"M J Cafferkey, G A Martin","doi":"10.1177/14782715241231331","DOIUrl":"10.1177/14782715241231331","url":null,"abstract":"<p><strong>Background: </strong>Physician-led thoracic ultrasound (TUS)-guided biopsies provide a prompt route to tissue diagnosis in pleural and peripheral lung malignancies. This retrospective study reviews the diagnostic performance and safety of this approach in a UK District General Hospital.</p><p><strong>Methods: </strong>Time to biopsy, diagnostic yield and complication rate were analysed in a cohort of 49 patients undergoing ultrasound-guided tissue sampling between September 2019 and December 2022.</p><p><strong>Results: </strong>Fifty-one TUS-guided biopsies were attempted. Mean time from decision to biopsy was 5 days. The overall diagnostic yield was 82%. Complication rate was low; 3 minor adverse effects were reported which led to no change in routine care.</p><p><strong>Conclusion: </strong>This single centre retrospective study shows that physician-led TUS-guided biopsy provides a safe and timely method of obtaining a tissue diagnosis in thoracic malignancy. It offers an alternative to computer tomography (CT)-guided or thoracoscopic biopsies and should be considered in selected patients where local procedural expertise exists.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features in this issue. 本期专题
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 DOI: 10.1177/14782715241244583
Graeme P Currie
{"title":"Features in this issue.","authors":"Graeme P Currie","doi":"10.1177/14782715241244583","DOIUrl":"10.1177/14782715241244583","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vincent Marks DM, FRCPE, FRCP, FRCPath. 文森特-马克斯 DM、FRCPE、FRCP、FRCPath。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2023-12-30 DOI: 10.1177/14782715231223049
Anthony Seaton
{"title":"Vincent Marks DM, FRCPE, FRCP, FRCPath.","authors":"Anthony Seaton","doi":"10.1177/14782715231223049","DOIUrl":"10.1177/14782715231223049","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139075456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospital at home: Opportunity knocks or opportunity costs? 在家住院：机会来临还是机会成本？
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-03-01 Epub Date: 2024-03-04 DOI: 10.1177/14782715241234082
Clare Bostock
{"title":"Hospital at home: Opportunity knocks or opportunity costs?","authors":"Clare Bostock","doi":"10.1177/14782715241234082","DOIUrl":"10.1177/14782715241234082","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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