Journal of the Royal College of Physicians of Edinburgh最新文献_第3页

Cranio-vertebral junction tuberculosis: Uncommon presentation of a common disease.

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-11-29 DOI: 10.1177/14782715241302224

Souradeep Chowdhury, Surabhi Vyas, Upendra Baitha, Pankaj Jorwal, Manish Soneja, Amandeep Singh

引用次数: 0

Delirium assessment, management and barriers to effective care across Scotland: A secondary analysis of survey data from World Delirium Awareness Day 2023.

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-11-29 DOI: 10.1177/14782715241301486

Fariha Naeem, Rose S Penfold, Roy L Soiza, Rebecca Von Haken, Heidi Lindroth, Keibun Liu, Peter Nydhal, Terry J Quinn

{"title":"Delirium assessment, management and barriers to effective care across Scotland: A secondary analysis of survey data from World Delirium Awareness Day 2023.","authors":"Fariha Naeem, Rose S Penfold, Roy L Soiza, Rebecca Von Haken, Heidi Lindroth, Keibun Liu, Peter Nydhal, Terry J Quinn","doi":"10.1177/14782715241301486","DOIUrl":"https://doi.org/10.1177/14782715241301486","url":null,"abstract":"Introduction: Delirium is a common, severe neuropsychiatric syndrome in hospitalised older adults. We evaluated use of validated delirium assessment tools, adherence to national guidelines and prevalence and management of delirium across Scotland, identifying barriers to effective care.Methods: Secondary analysis of national survey data, collected by participating clinicians on World Delirium Awareness Day (15 March 2023).Results: Among 120 responses (3,257 patients), the 4AT was the most frequently used assessment tool (75%), while 14% of units reported using clinical judgement alone. The delirium assessment rate was 74%, with a prevalence of 22% at 8 am. Management protocols varied, with frequent routine non-pharmacological interventions including pain management (88%), hydration (87%) and open family visiting (80%). Barriers to delirium care included insufficient staffing and training.Conclusion: While many hospital settings follow national delirium guidelines, some still rely on clinical judgement for assessment, with variability in management protocols and practices. We have highlighted key barriers to effective delirium care in Scotland.","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"14782715241301486"},"PeriodicalIF":1.1,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical femur fracture following romosozumab and bisphosphonate treatment. 罗莫单抗和双膦酸盐治疗后的非典型股骨骨折。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-11-23 DOI: 10.1177/14782715241301487

Mark Jacunski, Hanna Johnsson, Stuart H Ralston, Barbara Hauser

{"title":"Atypical femur fracture following romosozumab and bisphosphonate treatment.","authors":"Mark Jacunski, Hanna Johnsson, Stuart H Ralston, Barbara Hauser","doi":"10.1177/14782715241301487","DOIUrl":"https://doi.org/10.1177/14782715241301487","url":null,"abstract":"Romosozumab, a monoclonal antibody against sclerostin, is a newly licensed dual-acting osteoporosis treatment for patients at very high risk of fracture. Sclerostin inhibition leads to stimulation of bone formation and simultaneous inhibition of bone resorption. Only three cases of atypical femur fractures were reported out of 5,621 patients who received romosozumab in the pivotal randomised controlled trials FRAME and ARCH; however, most enrolled clinical trial patients were osteoporosis treatment-naïve or had a prolonged washout period. We report a case of an atypical femur fracture that occurred after the completion of romosozumab treatment which was followed by one dose of 5 mg intravenous zoledronic acid. The patient had previously received a 2-year course of subcutaneous teriparatide and subsequent three consecutive yearly intravenous zoledronic acid infusions, followed by a 2-year treatment break. This case highlights the risks of prolonged suppression of bone resorption, which includes romosozumab due to its dual action and the need for further research on how to minimise such deleterious medication effects. Patients who are switched from prolonged antiresorptive treatment to romosozumab, should be risk-assessed and counselled for the risk of atypical femur fracture.","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"14782715241301487"},"PeriodicalIF":1.1,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wild & Tame: Animals in history. 野性与驯服历史上的动物

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-09-23 DOI: 10.1177/14782715241288363

引用次数: 0

Rapidly progressive pulmonary actinomycosis. 快速进展的肺放线菌病。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-09-19 DOI: 10.1177/14782715241281805

Scott Hainey, Phil Reid, Andrew Wood

引用次数: 0

Can Ayurveda medicine supplement modern medical treatments in chronic disease management? 阿育吠陀医学能否辅助现代医学治疗慢性病？

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-08-22 DOI: 10.1177/14782715241273738

Vyshna Ravindran, Kanta Kumar, Sunil Bhandari, Kaushik Chattopadhyay, Unnikrishnan Payyappallimana, Antonio Morandi, Rajeev Gupta

引用次数: 0

Response to deep vein thrombosis: Implications of thromboprophylaxis after lower limb cast immobilisation. 对深静脉血栓形成的反应：下肢石膏固定后血栓预防的意义。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.1177/14782715241264851

Katherine Stark, Abhinav Mathur, Mohammed M Khan

引用次数: 0

Critical analysis of the subspecialty stroke medicine curriculum: Social and political influences on its design and professionalism. 对卒中医学亚专业课程的批判性分析：社会和政治对课程设计和专业性的影响。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1177/14782715241275176

Samia Gul, Muhammad Shahid

引用次数: 0

Metastasis to the skull base involving the sphenoid and cavernous sinus in hepatocellular carcinoma. 肝细胞癌转移至颅底，累及蝶窦和海绵窦：病例报告。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI: 10.1177/14782715241270368

Sukanta Dutta, Atanu Chandra, Saikot Ganai, Uddalak Chakraborty, Sumesh Pm

引用次数: 0

Safety, feasibility and efficacy of sonothrombolysis with micro boluses of perfluoropropane as a point of care therapy for patients with acute ST-elevation myocardial infarction. 将全氟丙烷微量栓剂超声溶栓作为急性ST段抬高型心肌梗死患者的护理点疗法的安全性、可行性和有效性。

IF 1.1

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI: 10.1177/14782715241273737

Pratheesh George Mathen, Jesu Krupa, Nathaniel Samson, Shohiab Mirza, Haynes Raja, Sakthivel Selvaraj, John Jose

{"title":"Safety, feasibility and efficacy of sonothrombolysis with micro boluses of perfluoropropane as a point of care therapy for patients with acute ST-elevation myocardial infarction.","authors":"Pratheesh George Mathen, Jesu Krupa, Nathaniel Samson, Shohiab Mirza, Haynes Raja, Sakthivel Selvaraj, John Jose","doi":"10.1177/14782715241273737","DOIUrl":"10.1177/14782715241273737","url":null,"abstract":"Background: Despite advances in timely revascularisation of ST elevation myocardial infarction (STEMI) patients, there are several practical and unavoidable delays. Sonothrombolysis (administered during micro boluses of Perfluoropropane) initiated bedside as a point-of-care therapy during the initial evaluation of the patient may potentially mitigate this by producing early culprit vessel revascularisation.Methods: This was a prospective, single-centre study on hemodynamically stable patients presenting within 12 hours of a first STEMI who consented for study participation.Results: Fifteen patients were recruited over a 1-month period. Eleven were male. Nine patients had anterior wall STEMI and left anterior descending as culprit vessel. There were no significant changes in safety outcomes. Median First Medical Contact (FMC)-Sono time was 12 min (10-15). Median duration of sonothrombolysis was 14 min (12-16). FMC-device time was 97 min (79-128). Six patients had culprit vessel recanalisation before primary percutaneous coronary intervention (PPCI) which was consistent with the reference rates of therapy-associated recanalisation (p = 0.535).Conclusion: Micro bolus sonothrombolysis maybe safely initiated as a point of care therapy adjunctive to PPCI in hemodynamically stable STEMI patients with reasonable efficacy. Further randomised trials are needed to ascertain its applicability in various geographical and clinical settings.","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"197-203"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0