{"title":"The People's Dispensary.","authors":"","doi":"10.1177/14782715251369558","DOIUrl":"10.1177/14782715251369558","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"243"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Racing against a stopped clock: Inequitable access to stroke thrombectomy.","authors":"Charlotte Squires, Aoife Duignan","doi":"10.1177/14782715251341065","DOIUrl":"10.1177/14782715251341065","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"230-231"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Haemochromatosis and infections.","authors":"Oscar Mp Jolobe","doi":"10.1177/14782715251344121","DOIUrl":"10.1177/14782715251344121","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"232-233"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Umbilicated papules in an immunocompromised patient.","authors":"Shreya K Gowda, Gomathy Sethuraman","doi":"10.1177/14782715251354953","DOIUrl":"10.1177/14782715251354953","url":null,"abstract":"<p><p>A 68-year-old male with HIV (CD4 count: 167 cells/mm³) presented with multiple umbilicated papules on the face and chest and a giant pedunculated nodule on the forehead, persisting for six months. Differential diagnoses included molluscum contagiosum, histoplasmosis, and cryptococcosis for the papules, and giant molluscum contagiosum or squamous cell carcinoma for the nodule. Histopathology revealed epidermal hyperplasia with Henderson Patterson bodies, confirming molluscum contagiosum. Fungal stains, cultures, and antigen tests for cryptococcosis and histoplasmosis were negative. The patient was started on highly active antiretroviral therapy (HAART) for immune reconstitution. This case underscores the importance of histopathology in differentiating molluscum contagiosum from opportunistic infections in immunocompromised patients and highlights HAART as a key therapeutic intervention.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"200-201"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonika Garg, Dishika Goyal, Chirantan S Talwar, Vishal Gaurav
{"title":"'White islands in a sea of red' in dengue fever: Recognising a distinct rash pattern.","authors":"Sonika Garg, Dishika Goyal, Chirantan S Talwar, Vishal Gaurav","doi":"10.1177/14782715251359807","DOIUrl":"10.1177/14782715251359807","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"205-206"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mrinal Kanti Das, Krishna Deb Barman, Ananya Sharma
{"title":"Voriconazole-induced photosensitivity and cheilitis.","authors":"Mrinal Kanti Das, Krishna Deb Barman, Ananya Sharma","doi":"10.1177/14782715251365359","DOIUrl":"10.1177/14782715251365359","url":null,"abstract":"<p><p>We present the case of a middle-aged man with orbital and maxillary invasive aspergillosis on treatment with oral voriconazole, who presented with photosensitivity, cracked lips and dark-brown hyperpigmentation of face, upper chest and trunk after 4 months of treatment. Photosensitvity occurs in 10%-20% of patients on treatment with voriconazole, and may even lead to cutaneous malignancies. Patient education about the phototoxic effects of voriconazole is essential at the outset of therapy.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"207-208"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute meningoencephalitis with subdural empyema associated with <i>Acanthamoeba</i> in an immunocompetent individual.","authors":"Samik Pramanik, Sugata Dasgupta, Samarendranath Samui, Atanu Chandra, Francis J Kattady, Moloy Makhal","doi":"10.1177/14782715251342120","DOIUrl":"10.1177/14782715251342120","url":null,"abstract":"<p><p><i>Acanthamoeba</i>-induced meningoencephalitis is a rare and frequently fatal condition. We describe a case of acute <i>Acanthamoeba</i> meningoencephalitis complicated by subdural empyema in a previously healthy 50-year-old man who presented with high-grade fever, neck stiffness and left-sided hemiparesis. Neuroimaging revealed a subdural collection in the right fronto-temporo-parietal region, while cerebrospinal fluid analysis demonstrated neutrophilic pleocytosis with trophozoites morphologically consistent with <i>Acanthamoeba</i> species. The patient underwent burr-hole evacuation of the subdural collection and was managed with antimicrobial therapy and supportive care. The patient achieved complete recovery and was discharged after 2 weeks. This case underscores the importance of considering <i>Acanthamoeba</i> as a potential etiological agent in meningoencephalitis, even among immunocompetent individuals and highlights the critical role of early diagnosis and timely intervention in improving clinical outcomes.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"184-187"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reframing failure; redefining success.","authors":"Clare Bostock","doi":"10.1177/14782715251368571","DOIUrl":"10.1177/14782715251368571","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"228-229"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronald Manorekang, Alison Eales, James Thomas, Veeran Subramaniam
{"title":"Increase in self-presenting patients with ST-elevation myocardial infarction to the emergency department.","authors":"Ronald Manorekang, Alison Eales, James Thomas, Veeran Subramaniam","doi":"10.1177/14782715251342287","DOIUrl":"10.1177/14782715251342287","url":null,"abstract":"<p><strong>Background: </strong>We provide data on self-presenting patients with a diagnosis of ST-elevation myocardial infarction (STEMI) from our local hospitals who were transferred to tertiary centres for primary percutaneous coronary intervention (PPCI).</p><p><strong>Methodology: </strong>An audit of self-presenting patients with STEMI who underwent PPCI from 1 April 2020 to 31 March 2023. Time variables and post-PPCI results were scrutinised.</p><p><strong>Results: </strong>A total of 126 patients were reviewed. There was a substantial increase in the number of self-presenting patients from 2020 to 2023 (23, 48 and 55, respectively, each year, <i>p</i> = 0.006). One hundred and one (80%) patients were men and 83 (66%) patients attended during out-of-hours. The median time from patients' registration to having an ECG was 20 min [interquartile range (IQR) 12-38], from ECG to receiving dual anti-platelet was 29 min (IQR 18-52), from a referral made to the regional PPCI centre to when patients left emergency department (ED) was 55 min (IQR 32-79), and total time patients spent in the ED was 126 min (IQR 88-174). One hundred and eleven (88%) patients had PPCI, mostly single vessel and 4 (3%) patients died within 30 days of PPCI.</p><p><strong>Conclusion: </strong>There is an increasing trend in self-presentation with chest pain diagnosed as STEMI, with suboptimal guideline-directed timely management.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"94-97"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Esophagitis dissecans superficialis: Often underdiagnosed entity.","authors":"Fazil Mohammed, Shiran Shetty, Megha Murali, Geetha Vasudevan, Balaji Musunuri","doi":"10.1177/14782715251322854","DOIUrl":"10.1177/14782715251322854","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"110-111"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}