Asian Journal of Urology最新文献

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Genitourinary toxicity after pelvic radiation: Prospective review of complex urological presentations 盆腔放射后泌尿生殖系统毒性:复杂泌尿学表现的前瞻性回顾
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.01.006
{"title":"Genitourinary toxicity after pelvic radiation: Prospective review of complex urological presentations","authors":"","doi":"10.1016/j.ajur.2023.01.006","DOIUrl":"10.1016/j.ajur.2023.01.006","url":null,"abstract":"<div><h3>Objective</h3><div>Recent randomised controlled trials underestimated the incidence of genitourinary (GU) complications occurring more than 5 years following pelvic radiotherapy. This study aimed to determine the burden of treatment at a single institution from late GU complications after pelvic radiotherapy.</div></div><div><h3>Methods</h3><div>A prospective study of all presentations for GU complications following pelvic radiotherapy at a tertiary urology department between November 2018 and November 2019 was performed. Subgroup analyses was performed on patients with prostate cancer (PCa) with late toxicity to compare patient demographics, radiotherapy, complications, and management factors.</div></div><div><h3>Results</h3><div>There were 117 hospital encounters involving 46 patients with a 56.4% repeat encounter rate<strong>.</strong> Patients with PCa were the predominant group (<em>n</em>=39, 84.8%). External beam radiotherapy was the most common treatment modality (<em>n</em>=41, 89.1%). The median time from radiotherapy to encounter was 8 (range 0–23) years. Radiation-induced haemorrhagic cystitis was the most common presentation (<em>n</em>=70, 59.8%). Forty-four (42.7%) encounters for GU toxicity were managed operatively and 33 (32.0%) involved a non-operative procedure. Nine patients required packed red cell transfusion, with a total of 154 units transfused<strong>.</strong> Patients with PCa who presented with late GU toxicity had higher median Radiotherapy Oncology Group grades (<em>p</em>=0.020), proportion of emergency admissions (<em>p</em>=0.047), and frequency of clot urinary retention (<em>p</em>&lt;0.001).</div></div><div><h3>Conclusion</h3><div>There is a high burden of elective and emergency urology workload attributed to late pelvic radiation toxicity. Late GU toxicity occurring ≥5 years after radiotherapy is common and often more severe.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 633-641"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48553924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An update on the use of stem cell therapy for erectile dysfunction 干细胞疗法治疗勃起功能障碍的最新进展
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.07.005
{"title":"An update on the use of stem cell therapy for erectile dysfunction","authors":"","doi":"10.1016/j.ajur.2023.07.005","DOIUrl":"10.1016/j.ajur.2023.07.005","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review aimed to analyze animal and human trial data to better understand the efficacy of stem cell therapy (SCT) for erectile dysfunction (ED) and the obstacles that may hinder its application in this field.</div></div><div><h3>Methods</h3><div>We searched electronic databases, including PubMed and Scopus, for published studies with the Medical Subject Heading terms of “erectile dysfunction” (AND) “stem cell therapy” (OR) “erectile dysfunction” (AND) “clinical trial of stem cell therapy” (OR) “stem cell therapy” (AND) “sexual dysfunction”. The search was limited to English-language journals and full papers only. The initial search resulted in 450 articles, of which 90 relevant to our aims were included in the analysis.</div></div><div><h3>Results</h3><div>ED is a multifactorial disease. Current treatment options rely on pharmacotherapy as well as surgical options. Patients may have side effects or unsatisfactory results following the use of these treatment options. SCT may restore pathophysiological changes leading to ED rather than treating the symptoms. It has been evaluated in animal models and shown promising results in humans. Results confirm that SCT does improve erectile function in animals with different types of SC use. In humans, evidence showed promising results, but the trials were heterogeneous and limited mainly by a lack of randomization and the small sample size. Many challenges could limit future research in this field, including ethical dilemmas, regulation, patient recruitment, the cost of therapy, and the lack of a standardized SCT regimen. Repairing and possibly replacing diseased cells, tissue, or organs and eventually retrieving normal function should always be the goals of any therapy, and this can only be guaranteed by SCT.</div></div><div><h3>Conclusion</h3><div>SCT is a potential and successful treatment for ED, particularly in patients who are resistant to the classic therapy. SCT may promote nerve regeneration and vascular cell regeneration, not only symptomatic treatment.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 530-544"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of recurrence risk in patients with non-muscle-invasive bladder cancer 预测非肌层浸润性膀胱癌患者的复发风险
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.04.007
{"title":"Prediction of recurrence risk in patients with non-muscle-invasive bladder cancer","authors":"","doi":"10.1016/j.ajur.2023.04.007","DOIUrl":"10.1016/j.ajur.2023.04.007","url":null,"abstract":"<div><h3>Objective</h3><div>Non-muscle-invasive bladder cancer (NMIBC) remains a common challenge in uro-oncology with conflicting reports on recurrence risk. This study aimed to elucidate the recurrence rate of NMIBC in the Cancer Clinic of Shahid Beheshti Hospital in Iran and to investigate related parameters affecting recurrence risk.</div></div><div><h3>Methods</h3><div>The data of 143 patients with NMIBC, who underwent treatment between January 2017 and January 2020 and were followed up from the initial transurethral resection of bladder tumor until November 30, 2020 in our institution, were retrospectively assessed. The Cox regression analysis and Kaplan–Meier plot of recurrence-free survival were used to determine independent contributing factors for tumor recurrence.</div></div><div><h3>Results</h3><div>Among patients with NMIBC, 83.9% were male, and 16.1% were female, with a mean age of 64.4 (standard deviation [SD] 12.9) years. During the follow-up, 71 (49.7%) patients showed tumor recurrence, with a mean recurrence time of 11.5 (SD 6.9) months. In the Chi-square test or Fisher's exact test, the age (≥65 years) (<em>p</em>=0.037), obesity (body mass index ≥30 kg/m<sup>2</sup>) (<em>p</em>=0.004), no diabetes mellitus (<em>p</em>=0.005), smoking (current or former smoker) (<em>p</em>=0.001), immediate perfusion therapy (<em>p</em>=0.035), number of tumors (&gt;3) (<em>p</em>&lt;0.001), and tumor stage (Ta, T1, and Tis) (<em>p</em>=0.001) had independent significant effects on the recurrence of NMIBC. The multivariate Cox regression analysis indicated that preoperative obesity (hazards ratio [HR] 7.90; 95% confidential interval [CI] 4.01–15.55; <em>p</em>&lt;0.001), current or former smoking (HR 1.85; 95% CI 1.07–3.20; <em>p</em>=0.027), and a high-grade tumor (HR 4.03; 95% CI 1.59–10.25; <em>p</em>=0.003) were significant predictors of tumor recurrence. The Kaplan–Meier plot of recurrence-free survival showed that obesity (log-rank <em>p</em>&lt;0.001), current or former smoking (log-rank <em>p</em>=0.001), and a high-grade tumor (log-rank <em>p</em>=0.006) were associated with a shorter time interval until the first tumor recurrence.</div></div><div><h3>Conclusion</h3><div>The study found a high recurrence rate of NMIBC in Iran from January 2017 to January 2020, with the obesity, smoking history, and the high-grade tumor as contributing factors.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 625-632"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140468533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of platelet-rich plasma intracavernous injection for patients with erectile dysfunction: A systematic review, meta-analysis, and meta-regression 富血小板血浆鞘膜内注射治疗勃起功能障碍患者的有效性和安全性:系统回顾、荟萃分析和荟萃回归
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.01.001
{"title":"Efficacy and safety of platelet-rich plasma intracavernous injection for patients with erectile dysfunction: A systematic review, meta-analysis, and meta-regression","authors":"","doi":"10.1016/j.ajur.2024.01.001","DOIUrl":"10.1016/j.ajur.2024.01.001","url":null,"abstract":"<div><h3>Objective</h3><div>Intracavernous injection might be offered to patients with erectile dysfunction (ED) who did not respond to the first-line oral treatment. Platelet-rich plasma (PRP) might offer improvement in erectile function since it contains numerous growth factors. This study aimed to evaluate the efficacy and safety of PRP intracavernous injection for patients with ED.</div></div><div><h3>Methods</h3><div>We conducted relevant literature searches on Cochrane Library, Medline, Scopus, and <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> databases using specific keywords. The results of continuous variables were pooled into the mean difference (MD) and dichotomous variables into the odds ratio along with 95% confidence interval (95% CI).</div></div><div><h3>Results</h3><div>A total of six studies were included. Our pooled analysis revealed that PRP intracavernous injection was associated with a significant increase in the erectile function domain of the International Index of Erectile Function at 1 month (MD 3.47 [95% CI 2.62–4.32], <em>p</em>&lt;0.00001, <em>I</em><sup>2</sup>=7%), 3 months (MD 3.19 [95% CI 2.25–4.12], <em>p</em>&lt;0.00001, <em>I</em><sup>2</sup>=0%), and 6 months (MD 3.21 [95% CI 2.30–4.13], <em>p</em>&lt;0.00001, <em>I</em><sup>2</sup>=0%) after the intervention when compared with baseline values. PRP was also superior to a placebo in terms of improvement in erectile function domain of the International Index of Erectile Function score at 1 month (MD 2.83, <em>p</em>&lt;0.00001), 3 months (MD 2.87, <em>p</em>&lt;0.00001), and 6 months (MD 3.20, <em>p</em>&lt;0.00001) post-intervention. The adverse events from PRP injection were only mild without any serious adverse events.</div></div><div><h3>Conclusion</h3><div>PRP intracavernous injection may offer benefits in improving erectile function in patients with ED with a relatively good safety profile.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 545-554"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation analysis between urinary crystals and upper urinary calculi 尿结晶与上尿路结石的相关性分析
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.04.003
{"title":"Correlation analysis between urinary crystals and upper urinary calculi","authors":"","doi":"10.1016/j.ajur.2024.04.003","DOIUrl":"10.1016/j.ajur.2024.04.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to analyze the correlation between urinary crystals and urinary calculi.</div></div><div><h3>Methods</h3><div>Clinical data, including urinary crystal types, were collected from 237 patients with urinary calculi. The detection rate of urine crystals and their correlation with stone composition were analyzed. The receiver operating characteristic curve analysis was used to determine the best cut-off value for predicting stone formation risk based on calcium oxalate crystals in urine.</div></div><div><h3>Results</h3><div>Calcium oxalate was the most common component in 237 patients. Among them, 201 (84.81%) patients had stones containing calcium oxalate. In these patients, calcium oxalate crystals were detected in 45.77% (92/201) of cases. In different groups of calcium oxalate stones, calcium oxalate crystals accounted for more than 90% of the total number of crystals detected in each group. The detection rate of calcium oxalate crystals was higher in first-time stone formers than in recurrent patients. The receiver operating characteristic curve analysis suggested a cut-off value of 110 crystals/μL for predicting stone formation, validated with 65 patients and 100 normal people.</div></div><div><h3>Conclusion</h3><div>Calcium oxalate crystals in urine can predict the composition of calcium oxalate stones and indicate a higher risk of stone formation when the number exceeds 110 crystals/μL. This non-invasive method may guide clinical treatment and prevention strategies.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 596-603"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LncRNA HCG18 promotes prostate cancer progression by regulating the miR-512-3p/HK-2 axis LncRNA HCG18通过调控miR-512-3p/HK-2轴促进前列腺癌进展
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.01.007
{"title":"LncRNA HCG18 promotes prostate cancer progression by regulating the miR-512-3p/HK-2 axis","authors":"","doi":"10.1016/j.ajur.2024.01.007","DOIUrl":"10.1016/j.ajur.2024.01.007","url":null,"abstract":"<div><h3>Objective</h3><div>Long non-coding RNAs (lncRNAs) play an important role in tumor progression. Numerous studies show that lncRNAs are strongly associated with prostate cancer (PCa) progression. The aim of this study was to investigate the pathway through which lncRNA <em>HCG18</em> regulates PCa progression by bioinformatics analysis and experiments.</div></div><div><h3>Methods</h3><div>We compared <em>HCG18</em> expression in PCa versus normal tissue and cells by data and cell lines, followed by comparing the changes in tumor cell proliferation, migration, and invasive ability after knockdown of <em>HCG18</em>. Then we searched for its downstream pathway by database and validated the pathway <em>in vivo</em> and <em>in vitro</em>.</div></div><div><h3>Results</h3><div><em>HCG18</em> was highly expressed in PCa and has the ability to promote tumor proliferation, migration, and invasion; knockdown of <em>HCG18</em> led to a decrease in the ability of cells to do so, which can be reversed by knockdown of miR-512-3p or overexpression of hexokinase 2.</div></div><div><h3>Conclusion</h3><div>Our <em>in vivo</em> and <em>in vitro</em> experiments suggest that <em>HCG18</em> can play a role in promoting PCa progression by blocking the inhibition of hexokinase 2 by miR-512-3p via sponge adsorption.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 575-585"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139818662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-assisted radical cystectomy with neobladder diversion in females: Safety profile and functional outcomes 女性机器人辅助根治性膀胱切除术与新膀胱转流术:安全性和功能性结果
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.02.008
{"title":"Robot-assisted radical cystectomy with neobladder diversion in females: Safety profile and functional outcomes","authors":"","doi":"10.1016/j.ajur.2024.02.008","DOIUrl":"10.1016/j.ajur.2024.02.008","url":null,"abstract":"<div><h3>Objective</h3><div>Radical cystectomy (RC) is a standard treatment for localized muscle invasive bladder cancer and high-risk or very high-risk non-muscle invasive bladder cancer not responding to adequate endovesical therapy. In women, traditionally RC is performed with hystero-adnexectomy and resection of the anterior vaginal wall, often resulting in sexual disorders. Vaginal-sparing techniques have been developed to improve functional outcomes. The present study explores the safety and the functional outcome of vaginal-sparing techniques.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed all consecutive female patients undergoing robot-assisted RC (RARC) with neobladder diversion between October 2017 and February 2022. The indications for vaginal-sparing RC were absence of tumor on bladder neck or urethra and no sign of infiltration of posterior bladder wall at the preoperative MRI. Functional results were evaluated with the aid of five questions out of the Bladder Cancer Index questionnaire. Complications were reported according to the Clavien–Dindo classification and cancer control was evaluated by recurrence-free and cancer-specific survival.</div></div><div><h3>Results</h3><div>A total of 22 female patients underwent RARC with neobladder diversion. Neoadjuvant chemotherapy was given in 17 (77%) cases. Clavien–Dindo grades III–IV complications occurred in four (18%) cases. After a mean follow-up of 29 (interquartile range 16–44) months, six (27.3%) patients developed distant metastases, and one (4.5%) woman loco-regional relapse. Sexual-sparing surgery was performed in 19 (86%) patients, and in the others the anterior vaginal wall was resected, but neobladder was still performed. During daytime, no patients reported total incontinence and 73% (11/15) reported total continence or only occasional leaks. Sexual results showed that seven of 15 (47%) women regained sexual activity after surgery, with a quality reported as “good” or “very good” in 40% of all 19 cases.</div></div><div><h3>Conclusion</h3><div>RARC in female with anterior vaginal wall preservation is feasible. The approach showed a good safety profile, with satisfying results on continence and sexual activity. Sexual-sparing approaches should be carried out after correct patient selection.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 618-624"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A diagnostic challenge: Eosinophilic cystitis masquerading as bladder cancer with seminal vesicle invasion 诊断难题:嗜酸性粒细胞性膀胱炎伪装成精囊受侵的膀胱癌
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.07.004
Anshuman Singh, Kasi Viswanath Gali, Vivek Pai, Padmaraj Hegde
{"title":"A diagnostic challenge: Eosinophilic cystitis masquerading as bladder cancer with seminal vesicle invasion","authors":"Anshuman Singh,&nbsp;Kasi Viswanath Gali,&nbsp;Vivek Pai,&nbsp;Padmaraj Hegde","doi":"10.1016/j.ajur.2023.07.004","DOIUrl":"10.1016/j.ajur.2023.07.004","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 669-670"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is fluoroscopy-free single-use flexible ureteroscopy a feasible treatment for kidney stones with abnormal renal anatomy? 对于肾解剖异常的肾结石,无荧光镜的一次性柔性输尿管镜是可行的治疗方法吗?
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.05.004
{"title":"Is fluoroscopy-free single-use flexible ureteroscopy a feasible treatment for kidney stones with abnormal renal anatomy?","authors":"","doi":"10.1016/j.ajur.2023.05.004","DOIUrl":"10.1016/j.ajur.2023.05.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the feasibility of the fluoroscopy-free single-use flexible ureteroscopy procedure in the treatment of kidney stones with abnormal renal anatomy compared to normal renal anatomy.</div></div><div><h3>Methods</h3><div>Forty patients with abnormal (Group A) and 80 patients with normal (Group B) renal anatomy who had 10–20 mm renal stones were included. They were treated with LithoVue single-use flexible ureteroscopy (Boston Scientific, Marlborough, MA, USA) after ureteric dilatation by two different size semi-rigid ureteroscopes. This technique was chosen as the aim was to exclude any ureteric pathology (<em>e.g.,</em> stone or stricture), confirm the placement of a safe guidewire, avoid balloon dilatation of the ureter, and achieve safe insertion of a 12 Fr, 35/45 cm ureteric access sheath with optical and tactile sign and without fluoroscopy image for guidance.</div></div><div><h3>Results</h3><div>The mean ages were 43 years and 45 years in Group A and Group B, respectively. The mean stone burden was 14.62 (standard deviation: 5.35) mm<sup>3</sup> and 14.79 (standard deviation: 4.58) mm<sup>3</sup> in Group A and Group B, respectively. There is no significant difference between both groups according to the mean operative time, hospital stay, or stone-free rate. The stone-free rate was about 93% in both groups when the stone size was between 10 mm and 15 mm, and less than 54% when the stone size was more than 15 mm to 20 mm. In the majority of cases (80.0% in Group A and 92.5% in Group B), we completed the procedure without fluoroscopy. The perioperative complication rates were comparable in the two groups.</div></div><div><h3>Conclusion</h3><div>Fluoroscopy-free single-use flexible ureteroscopy, when performed by expert urologists, is a feasible treatment for pre-stented patients with kidney calculi of ≤15 mm with abnormal renal anatomy.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 591-595"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45848567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Search trends in the treatment for benign prostatic hyperplasia: A twenty-year analysis 良性前列腺增生治疗的搜索趋势:二十年分析
IF 2.4 3区 医学
Asian Journal of Urology Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.08.009
{"title":"Search trends in the treatment for benign prostatic hyperplasia: A twenty-year analysis","authors":"","doi":"10.1016/j.ajur.2023.08.009","DOIUrl":"10.1016/j.ajur.2023.08.009","url":null,"abstract":"<div><h3>Objective</h3><div>Minimally invasive treatments for benign prostatic hyperplasia (BPH) have seen an increase in usage in recent years. We aimed to determine what types of events may influence patient search habits related to surgical BPH treatments.</div></div><div><h3>Methods</h3><div>Google Trends was used to determine the frequency of searches for different minimally invasive and prostatic ablative treatments for BPH in the United States. The procedures including transurethral resection of the prostate (TURP), Aquablation therapy (Aquablation), Greenlight laser therapy (Greenlight), transurethral needle ablation, transurethral microwave thermotherapy, Urolift (prostatic urethral lift [PUL]), Rezum, iTind, holmium laser enucleation of the prostate, simple prostatectomy, and prostatic artery embolization were compared.</div></div><div><h3>Results</h3><div>From January 1, 2004 to February 28, 2023, the number of internet search queries have increased for TURP, PUL, Rezum, prostatic artery embolization, and holmium laser enucleation of the prostate. There has been a slight decrease in searches for Greenlight, transurethral needle ablation, transurethral microwave thermotherapy, iTind, simple prostatectomy, and Aquablation.</div></div><div><h3>Conclusion</h3><div>Despite increased searches of alternatives, TURP remains the most searched BPH procedure. Additionally, search habits may be influenced by several factors including government approval, corporate acquisition, and marketing campaigns. It is important for physicians to understand the types of events that may cause patients to inquire about certain treatments for better quality health information and clinical visits.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"11 4","pages":"Pages 586-590"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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