Journal of Dual Diagnosis最新文献

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Sleep and Rest-Activity Rhythms in Recovering Patients with Severe Concurrent Mental and Substance Use Disorder: A Pilot Study. 重度精神和物质使用障碍恢复期患者的睡眠和休息-活动节律:一项初步研究。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2023-01-01 DOI: 10.1080/15504263.2022.2157694
Myriam Juda, Joanna Pater, Ralph E Mistlberger, Christian G Schütz
{"title":"Sleep and Rest-Activity Rhythms in Recovering Patients with Severe Concurrent Mental and Substance Use Disorder: A Pilot Study.","authors":"Myriam Juda,&nbsp;Joanna Pater,&nbsp;Ralph E Mistlberger,&nbsp;Christian G Schütz","doi":"10.1080/15504263.2022.2157694","DOIUrl":"https://doi.org/10.1080/15504263.2022.2157694","url":null,"abstract":"<p><p><b>Objective:</b> Mental health and substance use disorders are commonly associated with disrupted sleep and circadian rest-activity rhythms. How these disorders in combination relate to sleep and circadian organization is not well studied. We provide here the first quantitative assessment of sleep and rest-activity rhythms in inpatients with complex concurrent disorders, taking into account categories of substance use (stimulant <i>vs.</i> stimulant and opioid use) and psychiatric diagnosis (psychotic disorder and mood disorder). We also explore how sleep and rest-activity rhythms relate to psychiatric functioning. <b>Methods:</b> A total of 44 participants (10 female) between the age of 20-60 years (median = 29 years) wore wrist accelerometers over 5-70 days and completed standardized questionnaires assessing chronotype and psychiatric functioning (fatigue, psychiatric symptom severity, and impulsiveness). To examine potential influences from treatment, we computed (1) length of stay; (2) days of abstinence from stimulants and opioids as a measure of withdrawal; and (3) a sedative load based on prescribed medications. <b>Results:</b> Participants exhibited a sustained excessive sleep duration, frequent nighttime awakenings, and advanced rest-activity phase related to sedative load. Sleep disruptions were elevated in participants with a history of opioid use. Patients with a psychotic disorder showed the longest sleep and most fragmented and irregular rest-activity patterns. Non-parametric circadian rhythm analysis revealed a high rhythm amplitude by comparison with population norms, and this was associated with greater psychiatric symptom severity. Psychiatric symptom severity was also associated with greater fatigue and later MCTQ chronotype. <b>Conclusions:</b> This pilot study provides initial information on the prevalence and severity of sleep and circadian rhythm disturbances in individuals with severe concurrent disorders. The results underline the need for further studies to start to understand the role of sleep in the disease and recovery process in this understudied population.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"19 1","pages":"26-39"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9122929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewers for Journal of Dual Diagnosis. 双重诊断杂志的审稿人。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2023-01-01 DOI: 10.1080/15504263.2023.2160143
{"title":"Reviewers for <i>Journal of Dual Diagnosis</i>.","authors":"","doi":"10.1080/15504263.2023.2160143","DOIUrl":"https://doi.org/10.1080/15504263.2023.2160143","url":null,"abstract":"","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"19 1","pages":"I"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9179046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences Using Family or Peer Support for Smoking Cessation and Considerations for Support Interventions: A Qualitative Study in Persons With Mental Health Conditions. 使用家庭或同伴支持戒烟的经验和支持干预的考虑:一项心理健康状况者的定性研究。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2023-01-01 DOI: 10.1080/15504263.2022.2159732
Catherine S Nagawa, Ian A Lane, Maryann Davis, Bo Wang, Lori Pbert, Stephenie C Lemon, Rajani S Sadasivam
{"title":"Experiences Using Family or Peer Support for Smoking Cessation and Considerations for Support Interventions: A Qualitative Study in Persons With Mental Health Conditions.","authors":"Catherine S Nagawa,&nbsp;Ian A Lane,&nbsp;Maryann Davis,&nbsp;Bo Wang,&nbsp;Lori Pbert,&nbsp;Stephenie C Lemon,&nbsp;Rajani S Sadasivam","doi":"10.1080/15504263.2022.2159732","DOIUrl":"https://doi.org/10.1080/15504263.2022.2159732","url":null,"abstract":"<p><p><b>Background:</b> The current study aimed to understand how people with mental health conditions who currently smoke or recently quit engaged with family members or peers when quitting and assessed interest in involving family or peers in cessation interventions. <b>Methods:</b> Adults with mental health conditions who smoke or had quit within the past 5 years were recruited from publicly funded mental health programs (<i>N</i> = 24). We conducted virtual qualitative interviews between November 2020 and August 2021 and analyzed the data using the rapid thematic analytic approach. <b>Results:</b> Most participants were men (62%), and 71% were current smokers. We found that: having family/peers who were interested in quitting presented communal quitting opportunities, communication that facilitated quitting tended to be encouraging, and strong relationships with family members increased willingness to involve them in cessation interventions. But family or peer support was less helpful for individuals who were not ready to quit. <b>Conclusion:</b> Training family and peers to engage in supportive behaviors may promote cessation in this population. Cessation interventions may benefit from recruiting support partners who share a strong relationship with the smoker.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"19 1","pages":"40-48"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9215891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of Mental Health Measures and Retention in a Community-Based Perinatal Care Recovery Support Program for Women of Childbearing Age With Substance Use Disorder. 为有药物使用障碍的育龄妇女提供的社区围产期护理康复支持计划中心理健康措施与保留率的关系。
IF 1.5 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-10-01 Epub Date: 2022-09-29 DOI: 10.1080/15504263.2022.2124008
Matthew Hodges, Joanna E Chambers, Scott Denne, Sarah E Wiehe, Qing Tang, Seho Park, Debra Litzelman
{"title":"Associations of Mental Health Measures and Retention in a Community-Based Perinatal Care Recovery Support Program for Women of Childbearing Age With Substance Use Disorder.","authors":"Matthew Hodges, Joanna E Chambers, Scott Denne, Sarah E Wiehe, Qing Tang, Seho Park, Debra Litzelman","doi":"10.1080/15504263.2022.2124008","DOIUrl":"10.1080/15504263.2022.2124008","url":null,"abstract":"<p><p><b>Objective:</b> This research was undertaken to evaluate factors related to program retention among participants in a community-based peer recovery program for women of childbearing age with a history of substance use disorder. <b>Methods:</b> In all, 184 women of childbearing age with a history of substance use disorder were enrolled in a community-based peer recovery program. Half of the participants were pregnant or postpartum. The outcome of interest was retention in the program as measured at 2 and 6 months. Participants were paired with a peer recovery coach (PRC). PRCs were women with a personal history of substance use disorder who assisted with healthcare system navigation, facilitated access to local resources, and provided advice and emotional support. All PRCs were also licensed perinatal community health workers. Independent variables included gestational status, depression, anxiety, type and frequency of substance use, childhood trauma, abuse, readiness for treatment, and attachment patterns. <b>Results:</b> Anxiety was found to be a key factor associated with retention. Moderate anxiety was associated with higher rates of retention compared to normal to mild anxiety. Severe anxiety was associated with lower rates of retention compared to normal to mild anxiety. Attrition was highest in the first 2 months. <b>Conclusions:</b> Early integration with mental health services to address severe anxiety symptoms could potentially improve retention in substance use disorder recovery programs, thereby improving outcomes. More research is needed regarding severe anxiety and care-avoidant behaviors, particularly among women of childbearing age.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"18 4","pages":"211-219"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10760096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug-Free Community Support in Inpatients with Co-occurring Psychiatric Disorders and Substance Use Problems. 对合并精神疾病和药物使用问题住院患者的无药物社区支持。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-10-01 Epub Date: 2022-10-08 DOI: 10.1080/15504263.2022.2125605
Alexis Hammond, Marcelo Batkis, Phoebe Rostov, Haijuan Yan, Michael Kidorf
{"title":"Drug-Free Community Support in Inpatients with Co-occurring Psychiatric Disorders and Substance Use Problems.","authors":"Alexis Hammond,&nbsp;Marcelo Batkis,&nbsp;Phoebe Rostov,&nbsp;Haijuan Yan,&nbsp;Michael Kidorf","doi":"10.1080/15504263.2022.2125605","DOIUrl":"10.1080/15504263.2022.2125605","url":null,"abstract":"<p><p><b>Objective:</b> This study evaluated the presence of drug-free family and friends in the social networks of patients treated in an inpatient setting for co-occurring psychiatric disorders and substance use problems. <b>Methods:</b> Social network interviews were conducted with inpatients at the Johns Hopkins Bayview Acute Psychiatric Unit with co-occurring psychiatric disorders and substance use problems (<i>N</i> = 90). <b>Results:</b> Participants reported about five social network members, of which four were drug-free. Most participants (> 70%) were willing to include a drug-free person in the current inpatient treatment plan to support recovery efforts (<i>M</i> = 1.8 network members) and identified several areas of recovery support. <b>Conclusions:</b> These results demonstrate that people treated in an inpatient psychiatric setting have local drug-free family or friends that they are willing to include in the treatment process. These findings support further study of methods to mobilize network members to enhance social support during and following hospitalization.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"18 4","pages":"177-184"},"PeriodicalIF":2.2,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506628/pdf/nihms-1848220.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10297062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Review of Digital Interventions to Decrease Cannabis Use Among Patients With Comorbid Psychiatric Disorders. 减少合并精神病患者大麻使用的数字干预综述。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-10-01 Epub Date: 2022-09-30 DOI: 10.1080/15504263.2022.2126058
Laura Whiteley, Elizabeth M Olsen, Kayla K Haubrick, Chaerim Kang, Ian Vaughan, Larry K Brown
{"title":"A Review of Digital Interventions to Decrease Cannabis Use Among Patients With Comorbid Psychiatric Disorders.","authors":"Laura Whiteley,&nbsp;Elizabeth M Olsen,&nbsp;Kayla K Haubrick,&nbsp;Chaerim Kang,&nbsp;Ian Vaughan,&nbsp;Larry K Brown","doi":"10.1080/15504263.2022.2126058","DOIUrl":"10.1080/15504263.2022.2126058","url":null,"abstract":"<p><strong>Objective: </strong>Cannabis use disorder (CUD) is associated with an elevated risk for psychiatric disorders and symptoms, contributing to poor health outcomes and increased medical costs. Unfortunately, interventions that simultaneously address cannabis use and co-occurring psychiatric disorders are limited in availability. Targeted digital interventions to reduce cannabis use could be beneficial for patients with psychiatric disorders. Digital interventions could be easily disseminated and used in numerous clinical locations, including outpatient, inpatient, residential, and community psychiatric treatment settings.</p><p><strong>Methods: </strong>Literature on digital cannabis reduction interventions for persons with psychiatric disorders was examined between April 2021 and June 2021. Articles were obtained from PubMed and PsycINFO databases. English language randomized controlled trials (RCT), feasibility and acceptability studies, pilot studies, and published protocols were included.</p><p><strong>Results: </strong>There is significant evidence that digital interventions can effectively reduce cannabis use in general, non-clinical populations. However, there is less literature examining interventions for persons living with co-occurring psychiatric illness-most of which is tailored to patients living with chronic psychosis.</p><p><strong>Conclusions: </strong>There is great need for accessible and tailored digital interventions for co-occurring CUD and psychiatric disorders.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"18 4","pages":"199-210"},"PeriodicalIF":2.2,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311985/pdf/nihms-1891697.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10117608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Changes in Alcohol Consumption following Direct-Acting Antiviral Treatment for Hepatitis C in VA Patients with Comorbid Alcohol Use Disorder and PTSD. VA合并酒精使用障碍和创伤后应激障碍患者丙型肝炎直接抗病毒治疗后饮酒量的变化。
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-10-01 Epub Date: 2022-09-23 DOI: 10.1080/15504263.2022.2123119
Jessica E Hoyt, Nikhil Teja, Tammy Jiang, Luke Rozema, Jiang Gui, Bradley V Watts, Brian Shiner, Jaimie L Gradus
{"title":"Changes in Alcohol Consumption following Direct-Acting Antiviral Treatment for Hepatitis C in VA Patients with Comorbid Alcohol Use Disorder and PTSD.","authors":"Jessica E Hoyt, Nikhil Teja, Tammy Jiang, Luke Rozema, Jiang Gui, Bradley V Watts, Brian Shiner, Jaimie L Gradus","doi":"10.1080/15504263.2022.2123119","DOIUrl":"10.1080/15504263.2022.2123119","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether direct-acting antivirals (DAA) for hepatitis C viral infection (HCV): glecaprevir/pibrentasvir (GLE/PIB), ledipasvir/sofosbuvir (LDV/SOF), and sofosbuvir/velpatasvir (SOF/VEL) are associated with reduced alcohol consumption among veterans with alcohol use disorder (AUD) and co-occurring post-traumatic stress disorder (PTSD).</p><p><strong>Methods: </strong>We measured change in Alcohol Use Disorder Identification Test-Consumption Module (AUDIT-C) scores in a retrospective cohort of veterans with PTSD and AUD receiving DAAs for HCV.</p><p><strong>Results: </strong>One thousand two hundred and eleven patients were included (GLE/PIB <i>n</i> = 174, LDV/SOF <i>n</i> = 808, SOF/VEL <i>n</i> = 229). Adjusted frequencies of clinically meaningful improvement were 30.5% for GLE/PIB, 45.5% for LDV/SOF, and 40.5% for SOF/VEL. The frequency was lower for GLE/PIB than for LDV/SOF (<i>OR</i> = 0.59; 95% CI [0.40, 0.87]) or SOF/VEL (<i>OR</i> = 0.66; 95% CI [0.42, 1.04]).</p><p><strong>Conclusions: </strong>DAA treatment for HCV was associated with a substantial reduction in alcohol use in patients with AUD and co-occurring PTSD. Further exploration of the role of DAAs in AUD treatment is warranted.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":"18 4","pages":"185-198"},"PeriodicalIF":2.2,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719291/pdf/nihms-1848219.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10411118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploration of the Relationship Between Concussions and Depression Symptoms, Anxiety Symptoms, and Hazardous Drinking Among a Sample of College Students. 大学生脑震荡与抑郁症状、焦虑症状和危险饮酒关系的探讨
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-10-01 Epub Date: 2018-09-05 DOI: 10.1080/15504263.2018.1473906
Ryan J Martin, Beth H Chaney
{"title":"Exploration of the Relationship Between Concussions and Depression Symptoms, Anxiety Symptoms, and Hazardous Drinking Among a Sample of College Students.","authors":"Ryan J Martin,&nbsp;Beth H Chaney","doi":"10.1080/15504263.2018.1473906","DOIUrl":"https://doi.org/10.1080/15504263.2018.1473906","url":null,"abstract":"<p><p><b>Objective:</b> In clinical and athlete populations, research has found that experiencing a concussion (or traumatic brain injury) is correlated with experiencing other psychiatric conditions, including depression and alcohol problems. However, less is known about concussion comorbidity in other population segments. The purpose of this study is to examine the relationships between concussions and depression symptoms, anxiety symptoms, and hazardous drinking among a large sample of college students (<i>N</i> = 1776) enrolled in a mandatory health course. <b>Methods:</b> This study used an online health survey to examine concussion frequency (informal and formal diagnoses), sports-related concussions, depression symptoms, anxiety symptoms, and hazardous drinking in the sample. Bivariate and multivariate analyses were conducted to examine comorbid relationships between concussion frequency and the dependent variables of interest (anxiety symptoms, depression symptoms, and hazardous drinking). <b>Results:</b> We found that 691 (39.1%) participants indicated having at least one concussion. Analyses indicated that concussion frequency scores of both formal or informal diagnoses were significantly associated with scores of depression symptoms, anxiety symptoms, and hazardous drinking. When examining concussion frequency scores of only formal diagnoses, only hazardous drinking evidenced a statistically significant relationship. In addition, participants who had a sports concussion had significantly higher concussion frequency scores and hazardous drinking scores than those who have had a concussion that was not sport-related. <b>Conclusions:</b> The comorbid concussion relationships found in this study are consistent with those observed in clinical and athlete populations. It is important for college health professionals to be aware that concussion comorbidity is not limited to the athlete population and can impact the entire student body.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"220-227"},"PeriodicalIF":2.2,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/15504263.2018.1473906","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36464255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Eosinophils to Lymphocytes Ratio (ELR) as a Potential Inflammatory Biomarker in Patients with Dual Diagnosis of Bipolar and Alcohol Use Disorders: A Retrospective Cohort Study. 嗜酸性粒细胞与淋巴细胞比率(ELR)作为双相情感障碍和酒精使用障碍双重诊断患者的潜在炎症生物标志物:一项回顾性队列研究
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-07-01 Epub Date: 2022-06-29 DOI: 10.1080/15504263.2022.2090650
Elina Dirani, Rami Bou Khalil, Georges Raad, Sami Richa
{"title":"Eosinophils to Lymphocytes Ratio (ELR) as a Potential Inflammatory Biomarker in Patients with Dual Diagnosis of Bipolar and Alcohol Use Disorders: A Retrospective Cohort Study.","authors":"Elina Dirani,&nbsp;Rami Bou Khalil,&nbsp;Georges Raad,&nbsp;Sami Richa","doi":"10.1080/15504263.2022.2090650","DOIUrl":"https://doi.org/10.1080/15504263.2022.2090650","url":null,"abstract":"<p><p><b>Objective:</b> It is well-established that Bipolar Disorder (BD) has comorbidity with Alcohol Use Disorder (AUD) and could present the same symptoms of an underlying diagnosis of BD, therefore delaying the proper relevant treatment. Recent studies show the occurrence of alterations in the circulating levels of inflammatory mediators in patients dealing with AUD as well as those with BD. The objective of this study is to get an assessment of whether patients with AUD and BD comorbidity [BD(+)] would present different ratios of the Complete Blood Count (CBC) in comparison with patients with AUD but without a BD comorbidity [BD(-)]. <b>Methods:</b> This is a retrospective study, conducted through a selection of patients files who were admitted to the psychiatric department at Hôtel-Dieu de France University Hospital in Beirut, Lebanon, between January of the year 2016 and May of the year 2021. Overall, 83 files of patients dealing with AUD were included in this study. <b>Results:</b> Patients with BD(+) showed a higher Eosinophils to Lymphocytes Ratio (ELR) in comparison to those with BD(-). The Receiver Operation Characteristic (ROC) analysis had an area under the curve at 0.719 with a <i>p</i> = .001. The cutoff value of ELR that best differentiates BD(-) from BD(+) was 0.087 (Sensitivity = 81.3%; Specificity = 63.6%). The logistic regression analysis showed that an ELR superior to 0.087 presented a statistically significant difference, exposing patients belonging to the BD(+) group (<i>OR</i> = 11.66; <i>p</i> < .001). <b>Conclusions:</b> Our data suggest that ELR may be a valuable, reproducible, easily accessible, and cost-effective inflammatory marker, pointing at the presence of a BD comorbidity with AUD.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"144-152"},"PeriodicalIF":2.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40409193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
PTSD Avoidance Symptoms Associated With Alcohol Craving in Treatment-Seeking Veteran Population. 寻求治疗的退伍军人中PTSD回避症状与酒精渴望相关
IF 2.2 4区 医学
Journal of Dual Diagnosis Pub Date : 2022-07-01 Epub Date: 2022-06-27 DOI: 10.1080/15504263.2022.2089799
Aidan J Flynn, Gabriella Y Navarro, Heather K Basehore
{"title":"PTSD Avoidance Symptoms Associated With Alcohol Craving in Treatment-Seeking Veteran Population.","authors":"Aidan J Flynn,&nbsp;Gabriella Y Navarro,&nbsp;Heather K Basehore","doi":"10.1080/15504263.2022.2089799","DOIUrl":"https://doi.org/10.1080/15504263.2022.2089799","url":null,"abstract":"<p><p><b>Objective:</b> Posttraumatic stress disorder (PTSD) is one of the most frequently treated behavioral health conditions within the Department of Veterans Affairs and often co-occurs with alcohol or substance use. Past research suggests that alcohol and/or substance use may be used to cope with PTSD symptoms but there are inconsistent findings in how specific PTSD symptom clusters are associated with alcohol use disorder (AUD) or substance use disorder (SUD). Evaluating the relationship between PTSD symptom clusters and craving for individual drug of dependence may help explain these ambiguous results. <b>Methods:</b> Veterans (<i>N</i> = 167) recently engaged in mental health residential treatment were recruited to participate in a semi-structured diagnostic interview (Structured Clinical Interview for the <i>DSM-5</i>, Research Version [SCID-5-RV]) to assess for past 12-month history of AUD/SUD. Participants also completed the Posttraumatic Stress Disorder Checklist for <i>DSM-5</i> (PCL-5) to assess PTSD symptoms. <b>Results:</b> Covarying for severity of alcohol use, avoidance symptoms were significantly associated with alcohol craving for veterans with alcohol as their drug of dependence. Covarying for severity of stimulant use, no PTSD symptom clusters were associated with stimulant craving for veterans with stimulants as their drug of dependence. <b>Conclusions:</b> Veterans with high levels of PTSD avoidance symptoms may experience alcohol craving symptoms because they believe that alcohol use will eliminate or alleviate thoughts, feelings, or external reminders of the trauma. These results have important clinical implications in the treatment of co-occurring PTSD and AUD.</p>","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"135-143"},"PeriodicalIF":2.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40401312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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