Neurohospitalist最新文献_第4页

Midbrain Ischemic Stroke Manifesting With Rubral Tremor and Palato-Pharyngo-Laryngeal Myoclonus. 中脑缺血性中风表现为震颤和腭咽喉肌阵挛。

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Neurohospitalist Pub Date : 2025-01-22 DOI: 10.1177/19418744241313151

Shawn Banash, Jonathan Snider, Jeffrey R Vitt

引用次数: 0

Factor XIa Inhibitor Reversal in Intracranial Hemorrhage: A Case Report. 因子XIa抑制剂逆转颅内出血1例报告。

IF 0.9

Neurohospitalist Pub Date : 2025-01-21 DOI: 10.1177/19418744251314534

Arshed Al-Obeidi, Draia Garavito, Sierra Smalley, Kayla John, Lee Ann Jones, Nigel Key, Tamara Strohm

{"title":"Factor XIa Inhibitor Reversal in Intracranial Hemorrhage: A Case Report.","authors":"Arshed Al-Obeidi, Draia Garavito, Sierra Smalley, Kayla John, Lee Ann Jones, Nigel Key, Tamara Strohm","doi":"10.1177/19418744251314534","DOIUrl":"10.1177/19418744251314534","url":null,"abstract":"Background/objectives: There is currently no consensus regarding the optimal strategy for reversal of anticoagulation in life-threatening hemorrhage associated with factor XIa (FXIa) inhibitors.Methods: For this clinical case report, informed consent was obtained from surrogate.Results and discussion: Here, we present the case of an 82-year-old female who sustained a large subdural hematoma after a fall. Her aPTT on admission was elevated at 90.4 s and remained persistently prolonged at 90.9 s 12-hour after receiving an adequate dose of 4-factor prothrombin complex concentrate (PCC). She was found to have received a factor XIa inhibitor in a clinical trial, and subsequently received recombinant activated factor VII (rFVIIa) 2 mg (45 mcg/kg) as a one-time dose, and tranexamic acid (TXA) 1 g intravenously for reversal given her intracranial bleeding in the setting of trauma complicated by recent factor XIa inhibitor use. However, given her clinical decline and high surgical risk, the patient's family elected to withdraw care and she expired three days later. Reversal of FXIa inhibitors is challenging but may best be achieved using a combination of rFVIIa and TXA.Practical implications: Clinicians should consider administration of low dose recombinant activated factor VII (rFVIIa) in conjunction with an anti-fibrinolytic inhibitor such as tranexamic acid (TXA) for reversal of life-threatening hemorrhage in bleeding patients with exposure to novel factor XIa inhibitors that are currently in clinical trials.","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744251314534"},"PeriodicalIF":0.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Post-Stroke Post-Traumatic Stress Disorder. 中风后创伤后应激障碍的影响。

IF 0.9

Neurohospitalist Pub Date : 2025-01-15 DOI: 10.1177/19418744251315201

Swetha Renati, Sanita Raju, Alena Makarova, Marla Hairston, Kanita Beba Abadal, Andrea Bozeman, Henian Chen, Weiliang Cen, David Z Rose, W Scott Burgin

{"title":"Impact of Post-Stroke Post-Traumatic Stress Disorder.","authors":"Swetha Renati, Sanita Raju, Alena Makarova, Marla Hairston, Kanita Beba Abadal, Andrea Bozeman, Henian Chen, Weiliang Cen, David Z Rose, W Scott Burgin","doi":"10.1177/19418744251315201","DOIUrl":"10.1177/19418744251315201","url":null,"abstract":"Introduction: Post-Traumatic Stress Disorder (PTSD) is associated with exposure to traumatic events, especially in the military setting. However, patients who experience stroke may develop anxiety about their stroke event and may re-experience transient neurological symptoms as a result. A significant portion develop the persistent and disabling symptoms of PTSD.Methods: At the University of South Florida, we conducted a single-center, IRB-approved, observational pilot study of 20 adult patients who were diagnosed with stroke or transient ischemic attack (TIA) in the previous 31 days to 1 year. Patients completed the post-traumatic stress disorder checklist-5 (PCL-5), Patient Health Questionnaire-9 (PHQ-9), Stroke specific Quality of Life Scale (SS-QOL-12), Modified Rankin Scale of disability (mRS), and National Institutes of Health Stroke Scale (NIHSS) and provided blood and saliva samples.Results: All 20 subjects completed the PCL-5 and 19 subjects completed the follow up scales. Seven patients (35%) were found to have Post-Stroke Post-Traumatic Stress Disorder (PS-PTSD). Higher PCL-5 scores were significantly correlated with lower SS-QOL scores indicating worse quality of life (r = -0.709, P = .001) and higher PHQ-9 scores representing symptoms of depression (r = 0.727, P < 0.001).Conclusion: Post-Stroke Post-Traumatic Stress Disorder (PS-PTSD) is prevalent after stroke and TIA with patients experiencing concurrent depressive symptoms, correlating with a worsened quality of life.","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744251315201"},"PeriodicalIF":0.9,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Problem Solving: Two Patients With Gait Instability and Difficulty With Hand Coordination. 临床问题解决：两例步态不稳定及手协调困难患者。

IF 0.9

Neurohospitalist Pub Date : 2025-01-10 DOI: 10.1177/19418744251314210

Trevor Glenn, Amine Awad, Galina Gheihman, Alexis Roy

引用次数: 0

A 63 year-Old Male With a Painful Subacute Demyelinating Neuropathy. 一位63岁男性，患有疼痛性亚急性脱髓鞘神经病。

IF 0.9

Neurohospitalist Pub Date : 2025-01-10 DOI: 10.1177/19418744251314540

Audrey Blazek Ramsay, Kim Griffin, Michael Skolka, Michel Toledano, Marcus V Pinto

引用次数: 0

Beyond de Patient: A Lesson in Vigilance and Care. 超越病人：警惕与关怀的一堂课。

IF 0.9

Neurohospitalist Pub Date : 2025-01-05 DOI: 10.1177/19418744241310478

Mariana Peschard-Franco

引用次数: 0

"Cerebral Edema Leading to Subfalcine and Uncal Herniation in a Patient With Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations". 脑水肿导致视网膜血管病变伴脑白质脑病和全身性表现患者的癌下和肛门疝。

IF 0.9

Neurohospitalist Pub Date : 2024-12-20 DOI: 10.1177/19418744241310473

Parker Hughes, Liang Lu, Michael Shi, Danial Syed

{"title":"\"Cerebral Edema Leading to Subfalcine and Uncal Herniation in a Patient With Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations\".","authors":"Parker Hughes, Liang Lu, Michael Shi, Danial Syed","doi":"10.1177/19418744241310473","DOIUrl":"10.1177/19418744241310473","url":null,"abstract":"Deterioration of a patient's state of consciousness is among the most concerning signs encountered in clinical practice. The evaluation of this finding carries a broad initial differential diagnosis and must account for any relevant medical history. We describe the case of a 41-year-old male with known retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) who presented with progressive mental status decline and acute onset intractable headache. Head computed tomography (CT) revealed extensive vasogenic edema, resulting in right to left shift of 11 millimeters at the level of the lateral ventricles, with associated uncal and subfalcine herniation. He was treated with a 5-day course of methylprednisolone, leading to resolution of his lethargy and headache. Follow up neuroimaging with magnetic resonance (MRI) brain demonstrated interval improvement with the midline shift reduced to 3 millimeters after completion of high dose corticosteroids. Neurosurgical intervention was considered, but ultimately not required given his improvement. This case describes the management of life-threatening cerebral edema as a complication of RVCL-S disease progression. Due to the rarity of this disease, there are no standardized guidelines for treatment and the care for such patients relies on expert opinion, case studies, and extrapolation of principles learned from related conditions. Our intention is that the reporting of this case will contribute to the limited body of literature and aid those affected by this condition.","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744241310473"},"PeriodicalIF":0.9,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Curriculum Innovation: Clinical Documentation Integrity Education for Neurology Trainees. 课程创新：神经学实习生临床文献完整性教育。

IF 0.9

Neurohospitalist Pub Date : 2024-12-13 DOI: 10.1177/19418744241307685

Yasmin Aghajan, Bradley J Molyneaux

{"title":"Curriculum Innovation: Clinical Documentation Integrity Education for Neurology Trainees.","authors":"Yasmin Aghajan, Bradley J Molyneaux","doi":"10.1177/19418744241307685","DOIUrl":"10.1177/19418744241307685","url":null,"abstract":"Background and purpose: High quality clinical documentation is a fundamental skill for practicing physicians and important for quality improvement. However, documentation and coding are rarely integrated into medical education curricula and there is a lack of standard neurology curriculum on this topic. We developed and evaluated a teaching session on clinical documentation for neurology resident physicians.Methods: The education consisted of a didactic session designed by a neurologist with content about risk-adjusted mortality, clinical documentation integrity (CDI), impact of documentation on patients, and neurology-specific documentation guidance. A pre-post survey design was used to compare baseline and post-intervention self-reported knowledge and attitudes.Results: 61 responses were collected (37 pre- and 24 post-intervention). Residents had increased understanding of the impact of documentation on quality metrics (P = 0.004), risk-adjusted mortality (P < 0.0001), and impact on patients (P = 0.02). Attitude towards CDI education improved significantly (P = 0.0016), as well as agreement that CDI is important to resident physicians (P = 0.003). The portion of residents who agreed training on CDI is useful and valuable increased significantly (P = 0.004). 92% agreed this curriculum was useful, and 96% agreed they understood the role of CDI better after the session.Conclusions: In this study of a teaching session for neurology residents on clinical documentation, we found this format of teaching was well-received and highly effective in improving resident attitudes and self-reported knowledge.","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744241307685"},"PeriodicalIF":0.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple Central Nervous System Cryptococcomas Masquerading as Lymphoma. 伪装成淋巴瘤的多发性中枢神经系统隐球菌。

IF 0.9

Neurohospitalist Pub Date : 2024-12-09 DOI: 10.1177/19418744241307413

Alexander V Ortiz, Dhruven Mehta, Juli Horton, Adrian A Jarquin-Valdivia

引用次数: 0

Neurohospitalist Core Competencies. 核心能力。

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Neurohospitalist Pub Date : 2024-11-26 DOI: 10.1177/19418744241297187

Jana J Wold, Jetter Robertson, Jerome A Jeevarajan, Molly G Knox, Prateek Thatikunta, Guillermo E Solorzano, Kristin Galetta, Shefali Dujari, Tarini Goyal, Matthew E Ehrlich, Jonathan P Donnelly, Elizabeth Marriott, Vishal A Mandge, Roshni S Dhoot, Matthew W Luedke, Matthew B Maas, Margaret Y Yu, Michel Toledano, Rafid Mustafa, Jamie L Palaganas, Kathryn Kvam, Rachelle Dugue, Ethan Meltzer, Lahoud Touma, Maulik P Shah, Vanja C Douglas, Karen Orjuela, Brian J Scott, Joshua P Klein, David J Likosky, Jennifer R Simpson, Megan B Richie, Carolin Dohle, Jane G Morris, Carl A Gold

{"title":"Neurohospitalist Core Competencies.","authors":"Jana J Wold, Jetter Robertson, Jerome A Jeevarajan, Molly G Knox, Prateek Thatikunta, Guillermo E Solorzano, Kristin Galetta, Shefali Dujari, Tarini Goyal, Matthew E Ehrlich, Jonathan P Donnelly, Elizabeth Marriott, Vishal A Mandge, Roshni S Dhoot, Matthew W Luedke, Matthew B Maas, Margaret Y Yu, Michel Toledano, Rafid Mustafa, Jamie L Palaganas, Kathryn Kvam, Rachelle Dugue, Ethan Meltzer, Lahoud Touma, Maulik P Shah, Vanja C Douglas, Karen Orjuela, Brian J Scott, Joshua P Klein, David J Likosky, Jennifer R Simpson, Megan B Richie, Carolin Dohle, Jane G Morris, Carl A Gold","doi":"10.1177/19418744241297187","DOIUrl":"https://doi.org/10.1177/19418744241297187","url":null,"abstract":"The Neurohospitalist Core Competencies comprise a set of competency-based learning objectives that encapsulate the knowledge, skills, and attitudes of neurohospitalitists who specialize in the care of hospitalized patients with neurologic conditions. These competencies serve to characterize the rapidly expanding field of neurohospitalist medicine. The 27 chapters are divided into 3 sections entitled: neurological conditions, clinical interventions and interpretation of ancillary studies, and neurohospitalist role in the healthcare system. Each individual learning objective in the chapters describes a specific concept with an action verb to illustrate the behavior that the neurohospitalist exhibits. The individual neurohospitalist may not exhibit mastery in each of the topics included as individual practices vary in scope and practice pattern. A few examples of how the complete set of competencies may be used include in the creation of curricula for neurohospitalist fellowships, to assist in defining the scope of practice of neurohospitalists for administrative leaders of hospitals and departments, and in influencing the direction of further research and quality improvement in the field.","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744241297187"},"PeriodicalIF":0.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0