AIMS Microbiology最新文献_第10页

Methicillin-resistant Staphylococcus aureus as a cause of chronic wound infections: Alternative strategies for management. 耐甲氧西林金黄色葡萄球菌作为慢性伤口感染的原因:管理的替代策略。

IF 4.8

AIMS Microbiology Pub Date : 2022-04-24 eCollection Date: 2022-01-01 DOI: 10.3934/microbiol.2022011

Oriana Simonetti, Samuele Marasca, Matteo Candelora, Giulio Rizzetto, Giulia Radi, Elisa Molinelli, Lucia Brescini, Oscar Cirioni, Annamaria Offidani

引用次数: 10

Role of vitamin C in preventing of COVID-19 infection, progression and severity 维生素C在预防新冠肺炎感染、进展和严重程度中的作用

IF 4.8

AIMS Microbiology Pub Date : 2022-03-30 DOI: 10.3934/microbiol.2022010

U. Shahbaz, Nazira Fatima, Samra Basharat, A. Bibi, Xiaobin Yu, Muhammad Iftikhar Hussain, Maryam Nasrullah

{"title":"Role of vitamin C in preventing of COVID-19 infection, progression and severity","authors":"U. Shahbaz, Nazira Fatima, Samra Basharat, A. Bibi, Xiaobin Yu, Muhammad Iftikhar Hussain, Maryam Nasrullah","doi":"10.3934/microbiol.2022010","DOIUrl":"https://doi.org/10.3934/microbiol.2022010","url":null,"abstract":"Vitamin C stands as an essential water-soluble vitamin, antioxidant and has been shown to enhance immunity. SARS-CoV-2 has been spreading rapidly across the worldwide, several cellular processes of innate and adaptive immunity are aided by vitamin C, which strengthens the immune system overall. Multiple lines of evidence in the literature associate vitamin C with antioxidant, anti-inflammatory, anticoagulant and immunomodulatory actions. Pneumonia and sepsis patients had poor ascorbic acid status and high oxidative stress, according to many studies. Pneumonia patients who get vitamin C may have less severe symptoms and a longer course of the illness if they do. To standardize plasma levels in sepsis patients, gram measurements of the vitamin must be administered intravenously (IV). This intervention has been shown in a few trials to reduce mortality. COVID-19 management in China and the United States has exhibited remarkable results when using a high percentage of intravenous vitamins C. It's acceptable to include vitamin C in the COVID-19 treatment protocol as a secondary measure based on the current active clinical studies looking at the impact of vitamin C on the management of COVID-19. Patients with hypovitaminosis C or severe respiratory illnesses, such as COVID-19, may benefit from taking vitamin C, due to its good safety profile, simplicity of use, and potential for rapid production scaling. The study's goal was to see whether high dosage intravenous vitamin C had any impact on individuals with severe COVID-19 (HDIVC). Finally we discuss recent research that has been published on the efficacy of vitamin C administration in the treatment of viral infection and life-threatening conditions. The purpose of this manuscript is to summarise existing research on the efficacy of vitamin C as a treatment for COVID-19 and to discuss possible explanations for why it may work in some individuals but not in others.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"108 - 124"},"PeriodicalIF":4.8,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48247809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Application of biological systems and processes employing microbes and algae to Reduce, Recycle, Reuse (3Rs) for the sustainability of circular bioeconomy 利用微生物和藻类减少、回收和再利用（3Rs）的生物系统和工艺的应用，以实现循环生物经济的可持续性

IF 4.8

AIMS Microbiology Pub Date : 2022-03-28 DOI: 10.3934/microbiol.2022008

Divakar Dahiya, H. Sharma, A. Rai, P. Nigam

{"title":"Application of biological systems and processes employing microbes and algae to Reduce, Recycle, Reuse (3Rs) for the sustainability of circular bioeconomy","authors":"Divakar Dahiya, H. Sharma, A. Rai, P. Nigam","doi":"10.3934/microbiol.2022008","DOIUrl":"https://doi.org/10.3934/microbiol.2022008","url":null,"abstract":"The circular bioeconomy has undoubtedly gained global momentum during the last few years. The bioeconomy envisions “3R”, the goal of 3R (Reduce, Recycle, Reuse) is to implement in circular economy preventing excessive and unnecessary wastes. The circular bioeconomy emphasizes the best use of all sorts of available bioresources through the reduction of generated wastes during product formation, recycling of generated wastes, and reuse of valuable by-products and residues. Biotechnology could be useful in utilizing the resources to the optimum and therefore the role of biological agents and bioprocesses is of prime importance. In this review, we highlight the paramount importance of beneficial strains of microorganisms, macro, and microalgae in the bioeconomy. Microorganisms are universally recognized for the notable production of a vast array of secondary metabolites and other functionalities with possible use in various sectors. The application of potential strains in industries and modern agriculture practices could progressively improve the effective yield of food and feed, including fertilization of arid soils, bioconversion of by-products from industrial processes, and agriculture wastes. The valuable properties of specifically selected biological agents typically make them suitable candidates for their efficient contribution to circular bioeconomy without hampering the environment.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"83 - 102"},"PeriodicalIF":4.8,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45674736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Prevalence of pks genotoxin among hospital-acquired Klebsiella pneumoniae 医院获得性肺炎克雷伯菌中pks基因毒素的流行

IF 4.8

AIMS Microbiology Pub Date : 2022-03-22 DOI: 10.3934/microbiol.2022007

A. El-Ashry, Shimaa R. Hendawy, N. Mahmoud

{"title":"Prevalence of pks genotoxin among hospital-acquired Klebsiella pneumoniae","authors":"A. El-Ashry, Shimaa R. Hendawy, N. Mahmoud","doi":"10.3934/microbiol.2022007","DOIUrl":"https://doi.org/10.3934/microbiol.2022007","url":null,"abstract":"The pks genotoxic K. pneumoniae has recently triggered a widespread alarm. DNA damage and higher virulence have been linked to colibactin, a genotoxin expressed by the pks genomic island. Little is known about its molecular epidemiology in clinical isolates from Egypt. Therefore, this study was conducted to determine the prevalence and the microbiological and clinical features of pks harboring hospital-acquired K. pneumoniae isolates from Egypt. Eighty-seven hospital-acquired K. pneumoniae isolates from various specimen types were screened for pks colibactin island markers clbB, clbQ, clbA, and clbN by PCR. The pks-positive hvKp isolates were classified to one of the capsular types K1 and K2 using multiplex-PCR targeting K-serotype wzi and rmpA genes. The prevalence of pks+ strains was 27.6% (24/87). K1 capsular type, phenotypic, and genotypic hypervirulent isolates were significantly higher among pks+ strains than pks− strains (P < 0.001), while pks+ K. pneumoniae strains were found to be significantly less resistant to 8 of the antibiotic compounds tested than pks− strains. Carriage of K1 capsular type and mucoviscosity-associated rmp A gene and diabetes mellitus were identified to remain independent risk factors having a substantial association to pks-positivity by multivariate regression analysis. In conclusion, Hospital-acquired K. pneumoniae isolates in Egypt had an increased prevalence of the pks colibactin genotoxin. The significant occurrence of hypervirulent determinants in pks+ K. pneumoniae highlighted the genotoxin's possible pathogenicity combined with its distribution in several specimen types, which necessitates clinical attention and epidemic tracking.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"73 - 82"},"PeriodicalIF":4.8,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44461223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Comparative genome analysis of the first Listeria monocytogenes core genome multi-locus sequence types CT2050 AND CT2051 strains with their close relatives 首株单核增生李斯特菌核心基因组多位点序列型CT2050和CT2051与近缘菌株的比较基因组分析

IF 4.8

AIMS Microbiology Pub Date : 2022-03-21 DOI: 10.3934/microbiol.2022006

O. Nwaiwu

引用次数: 0

Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides 双歧杆菌的生长受到游离脂肪酸和胆汁盐的抑制，但不受甘油酯的抑制

IF 4.8

AIMS Microbiology Pub Date : 2022-03-10 DOI: 10.3934/microbiol.2022005

S. Pérez-Burillo, Sumudu Rajakaruna, O. Paliy

引用次数: 2

Microbial quality of edible seeds commercially available in southern Portugal 葡萄牙南部市售食用种子的微生物质量

IF 4.8

AIMS Microbiology Pub Date : 2022-02-22 DOI: 10.3934/microbiol.2022004

D. Silva, Patrícia O. Nunes, J. Melo, C. Quintas

{"title":"Microbial quality of edible seeds commercially available in southern Portugal","authors":"D. Silva, Patrícia O. Nunes, J. Melo, C. Quintas","doi":"10.3934/microbiol.2022004","DOIUrl":"https://doi.org/10.3934/microbiol.2022004","url":null,"abstract":"In the present work, the microbiological quality of sesame, flaxseed, chia, pumpkin sunflower seeds, a mix of seeds, as well as flaxseed flour, marketed in southern Portugal, were studied through the counting of aerobic microorganisms at 30 °C (AM), molds and yeast (M&Y), Escherichia coli (β-glucuronidase positive) (β-GP E. coli), Staphylococcus coagulase positive, and detection of Salmonella spp. The persistence of AM and M&Y populations were also counted in organic and non-organic flaxseed at 20 °C for 11 months. The seeds with the highest average of AM were flaxseed (1.3 x 106 CFU/g) followed by flaxseed flour (1.1 x 106 CFU/g) while the lowest level was found in chia (2.9 x 104 CFU/g). This seed also presented the lowest average values of filamentous fungi (9.8 x 102 CFU/g), whereas sunflower seeds had the highest levels (1.7 x 105 CFU/g). Flaxseed flour had the highest yeast counts (1.5 x 104 CFU/g). Although some samples had high levels of AM and fungi, β-GP E. coli and Salmonella were not detected, therefore, they complied with the microbiological criteria of the European Union. The organic flaxseed contained higher numbers of AM and M&Y than the non-organic ones (p < 0.05). In addition, the storage of flaxseed at 20 °C resulted in changes of AM and M&Y, showing that these populations were able to remain viable after eleven months (AM Log 5.4–Log 5.6; M&Y Log 2.8–Log 4.1). The results obtained in the present study, namely those high levels of AM and fungi (>106 and 104 CFU/g respectively), alert to the need of improving processing practices, storage/distribution conditions of edible seeds and derivatives, as well as the requirement of implementing adequate decontamination techniques.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"42 - 52"},"PeriodicalIF":4.8,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41776096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of olive and date palm by-products on rumen methanogenic community in Barki sheep 橄榄和椰枣副产物对Barki绵羊瘤胃产甲烷群落的影响

IF 4.8

AIMS Microbiology Pub Date : 2022-01-27 DOI: 10.3934/microbiol.2022003

A. Rabee, K. Kewan, H. E. El Shaer, M. Lamara, Ebrahim A Sabra

{"title":"Effect of olive and date palm by-products on rumen methanogenic community in Barki sheep","authors":"A. Rabee, K. Kewan, H. E. El Shaer, M. Lamara, Ebrahim A Sabra","doi":"10.3934/microbiol.2022003","DOIUrl":"https://doi.org/10.3934/microbiol.2022003","url":null,"abstract":"Rumen methanogens prevent the accumulation of fermentation gases in the rumen and generate methane that increases global warming and represents a loss in animals' gross energy. Non-traditional feed resources such as the by-products of date palm (Phoenix dactylifera) and olive (Olea europaea) trees have received attention to be used in animal feeding. This study evaluated the impact of non-traditional feed resources including olive cake (OC), discarded dates (DD), and date palm frond (DPF) in sheep diet on rumen fermentation, diversity and relative abundance of rumen methanogens. Nine adult rams were assigned to three equal groups and fed three diets: traditional concentrates mixture (S1); non-traditional concentrate mixture (S2) based on DD and OC; and (S3) composed of the same S2 concentrate supplemented with DPF as a roughage part. The results showed that rumen pH was higher with S3 diet than the other two diets. However, the S1 diet showed the highest values of total volatile fatty acids (TVFA) and rumen ammonia. In addition, the proportions of acetic and butyric acids were increased, whereas propionic acid declined in S2 and S3 compared to the S1 diet. Rumen methanogens were dominated by Methanobrevibacter that showed a numeric decline by including DD, OC, and DPF in the animal diets. Principal component analysis (PCA) based on rumen fermentation parameters and relative abundances of methanogens genera showed three distinct clusters. Also, positive and negative correlations were revealed between methanogens genera and rumen metabolites. This study expands the knowledge regarding the effect of agricultural byproducts on rumen fermentation and the methanogenic community.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"26 - 41"},"PeriodicalIF":4.8,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45533935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Diversity and bioprospecting for industrial hydrolytic enzymes of microbial communities isolated from deserted areas of south-east Morocco. 摩洛哥东南部荒无人烟地区分离的微生物群落的工业水解酶的多样性和生物勘探

IF 2.7

AIMS Microbiology Pub Date : 2022-01-20 eCollection Date: 2022-01-01 DOI: 10.3934/microbiol.2022002

Amina Manni, Abdelkarim Filali-Maltouf

{"title":"Diversity and bioprospecting for industrial hydrolytic enzymes of microbial communities isolated from deserted areas of south-east Morocco.","authors":"Amina Manni, Abdelkarim Filali-Maltouf","doi":"10.3934/microbiol.2022002","DOIUrl":"10.3934/microbiol.2022002","url":null,"abstract":"The current study aimed to analyze bacterial communities' diversity and abundance in three different deserted areas (Merzouga, Mhamid Elghizlane, and Erg lihoud) located in Moroccan Sahara, as well as to investigate osmotolerant microorganisms producing hydrolytic enzymes. The isolates were taxonomically affiliated using 16S rRNA gene sequencing. Four different hydrolase activities (amylase, lipase, cellulase, and protease) and osmotic stress tolerance were evaluated. The phylogenetic analysis of 364 screened isolates belonged to three phyla (Firmicutes 73%, Proteobacteria 26% and Actinobacteria 1%) and 18 different genera, from Bacillus, Ornithinibacillus, Paenibacillus, Geobacillus, Pseudomonas, Acinetobacter, Agrobacterium, Arthrobacter, Paenarthrobacter, Enterobacter, Staphylococcus, Erwinia, Herbasprillum, Ocuria, Massilia, Planomicrobium, Hodococcus, and Stenotrophomonas. The results detected a high proportion of osmotolerant and enzymes producing bacteria, many isolates can tolerate up to 55 °C (40%, 28%, and 30% in Merzouga, Mhamid Elghizlane, and Erg lihoudi, respectively). Meanwhile, the salinity tolerance reached 12% in some isolates with different proportions in each site, 29% in Merzouga, 24% in Mhamid Elghizlane, and 9% in Erg lihoudi. Furthermore, the enzymatic tests showed the presence of an amylolytic, lipolytic, cellulolytic, proteolytic activities in 20%, 31%, 63% and 72% of total strains, respectively. As a result, the present study is thus a preliminary yet critical step towards identifying the best bacterial candidates for further biotechnological applications.","PeriodicalId":46108,"journal":{"name":"AIMS Microbiology","volume":"8 1","pages":"5-25"},"PeriodicalIF":2.7,"publicationDate":"2022-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49254929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial agents and microbial ecology 抗菌剂与微生物生态学

IF 4.8

AIMS Microbiology Pub Date : 2022-01-06 DOI: 10.3934/microbiol.2022001

P. Di Martino

引用次数: 1