Quantitative Biology最新文献_第8页

Cistrome Data Browser and Toolkit: analyzing human and mouse genomic data using compendia of ChIP-seq and chromatin accessibility data Cistrome数据浏览器和工具包:使用ChIP-seq和染色质可及性数据的概要分析人类和小鼠基因组数据

IF 3.1 4区生物学

Quantitative Biology Pub Date : 2020-05-04 DOI: 10.1007/s40484-020-0204-7

Rongbin Zheng, Xin Dong, Changxin Wan, Xiaoying Shi, Xiaoyan Zhang, Clifford A. Meyer

引用次数: 8

Applications of probability and statistics in cancer genomics 概率与统计学在癌症基因组学中的应用

IF 3.1 4区生物学

Quantitative Biology Pub Date : 2020-04-29 DOI: 10.1007/s40484-020-0203-8

Xiaotu Ma, Sasi Arunachalam, Yanling Liu

引用次数: 0

Infrared imageries of human body activated by teas indicate the existence of meridian system 茶激活人体的红外图像表明经络系统的存在

IF 3.1 4区生物学

Quantitative Biology Pub Date : 2020-04-13 DOI: 10.21203/rs.3.rs-20030/v1

Wenli Jin, Yi Tao, Chen Wang, Lufei Wang, Xue Ao, Mingjie Su, Binwei Hu, Yuxiao Ouyang, Jiaxing Liu, Hui Li

{"title":"Infrared imageries of human body activated by teas indicate the existence of meridian system","authors":"Wenli Jin, Yi Tao, Chen Wang, Lufei Wang, Xue Ao, Mingjie Su, Binwei Hu, Yuxiao Ouyang, Jiaxing Liu, Hui Li","doi":"10.21203/rs.3.rs-20030/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-20030/v1","url":null,"abstract":"\u0000 BackgroundHuman meridian (Jingluo) system was hypothesized by traditional Chinese medicine (TCM) for thousands of years. In this hypothesis, there believed to be twelve formal meridian channels going through respective organs, carrying fluid and energy, and laying thermal effects. Some treatments based on meridians have been proved effective. However, existence of meridians has never been confirmed. The infrared photograph was employed to display the picture to the meridians since 1970. Unfortunately, no satisfactory results have been obtained. We think that only when a certain meridian is activated will there be thermal effect for successful infrared photograph.Methods We selected thirteen types of tea out of the herbs to activate the hypothesized twelve meridians for imagery taking. We collected 42 volunteers to drink teas and take infrared imageries in thirteen days. After every tea was drunk, infrared imageries of the human bodies were taken immediately. The highest temperatures of the fingers, palms, and above the organs were derived from the imageries. The averages and standard deviations of the standardized data of volunteers were calculated. Significances of the temperature difference among the body areas after drinking different teas were evaluated. ResultsWe found that the temperatures of the organs and fingers possibly connected by twelve hypothesized meridians rose together significantly, i.e., the thumbs and lung after white teas, index fingers and colon after blue teas, middle fingers and thymus after dark black teas, ring fingers and gallbladder after red black teas, little fingers and heart after yellow teas. The temperature distribution on the human bodies exhibited twelve patterns following the meridian hypothesis. Infrared imageries showed quite clear shapes of the organs activated by the teas, e.g., heart and kidneys by yellow teas, thymus by dark black teas, lungs and spleen by white teas, gallbladder and thyroid by red black teas, etc. Some high temperature lines also matched the hypothetic meridians. ConclusionsOur work displayed the imageries of the possible meridians for the first time, and proved with data that different foods may activate different organs following the meridian hypothesis, shedding light on a possible new method of targeted drug designs.","PeriodicalId":45660,"journal":{"name":"Quantitative Biology","volume":"1 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2020-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45278489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A pan-cancer integrative pathway analysis of multi-omics data 多组学数据的泛癌综合通路分析

IF 3.1 4区生物学

Quantitative Biology Pub Date : 2020-03-16 DOI: 10.1007/s40484-019-0185-6

Henry Linder, Yuping Zhang

引用次数: 1

Chao Tang: a self-motivated scientist pursues interdisciplinary excellence 超唐:一个有上进心的科学家，追求跨学科的卓越

IF 3.1 4区生物学

Quantitative Biology Pub Date : 2020-03-01 DOI: 10.1007/s40484-020-0198-1

Ya-Yuan Huang, Yimeng Ye, Jiang Zhang

引用次数: 2

Construction of a CRISPR-based paired-sgRNA library for chromosomal deletion of long non-coding RNAs 基于CRISPR的配对sgRNA文库的构建用于长非编码RNA的染色体缺失