Clinical Reviews in Bone and Mineral Metabolism最新文献

{"title":"Association Between Social Support and Bone Health Outcomes: a Systematic Review","authors":"Y. Youm, Seungwon Lee, E. Baldina","doi":"10.1007/s12018-018-9248-x","DOIUrl":"https://doi.org/10.1007/s12018-018-9248-x","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"74-86"},"PeriodicalIF":1.8,"publicationDate":"2018-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9248-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45728123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Status in the North African Population: a Review","authors":"A. El Maataoui, Z. Ouzzif","doi":"10.1007/s12018-018-9247-y","DOIUrl":"https://doi.org/10.1007/s12018-018-9247-y","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"67-73"},"PeriodicalIF":1.8,"publicationDate":"2018-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9247-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42411325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skeletal Effects of Thyroid Hormones","authors":"Bence Bakos, I. Takács, P. Stern, P. Lakatos","doi":"10.1007/s12018-018-9246-z","DOIUrl":"https://doi.org/10.1007/s12018-018-9246-z","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"57-66"},"PeriodicalIF":1.8,"publicationDate":"2018-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9246-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47156747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testosterone and Male Osteoporosis","authors":"Dong-Eun Shin, T. Ahn, Jee-Woong Kim, Chi-Hoon Oh, SeongJu Choi","doi":"10.1007/s12018-018-9245-0","DOIUrl":"https://doi.org/10.1007/s12018-018-9245-0","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"49-56"},"PeriodicalIF":1.8,"publicationDate":"2018-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9245-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48338298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLUCOCORTICOID EXCESS IN BONE AND MUSCLE.","authors":"Amy Y Sato,&nbsp;Munro Peacock,&nbsp;Teresita Bellido","doi":"10.1007/s12018-018-9242-3","DOIUrl":"https://doi.org/10.1007/s12018-018-9242-3","url":null,"abstract":"<p><p>Glucocorticoids (GC), produced and released by the adrenal glands, regulate numerous physiological processes in a wide range of tissues. Because of their profound immunosuppressive and anti-inflammatory actions, GC are extensively used for the treatment of immune and inflammatory conditions, the management of organ transplantation, and as a component of chemotherapy regimens for cancers. However, both pathologic endogenous elevation and long-term use of exogenous GC are associated with severe adverse effects. In particular, excess GC has devastating effects on the musculoskeletal system. GC increase bone resorption and decrease formation leading to bone loss, microarchitectural deterioration and fracture. GC also induce loss of muscle mass and strength leading to an increased incidence of falls. The combined effects on bone and muscle account for the increased fracture risk with GC. This review summarizes the advance in knowledge in the last two decades about the mechanisms of action of GC in bone and muscle and the attempts to interfere with the damaging actions of GC in these tissues with the goal of developing more effective therapeutic strategies.</p>","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"33-47"},"PeriodicalIF":1.8,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9242-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36273671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress and Insufficiency Fractures","authors":"J. Shaker","doi":"10.1007/s12018-017-9239-3","DOIUrl":"https://doi.org/10.1007/s12018-017-9239-3","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"3-15"},"PeriodicalIF":1.8,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-017-9239-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42223718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2018—Changing Times for CRBM","authors":"M. Allen","doi":"10.1007/s12018-018-9244-1","DOIUrl":"https://doi.org/10.1007/s12018-018-9244-1","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"1-2"},"PeriodicalIF":1.8,"publicationDate":"2018-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9244-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47802459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Bazedoxifene on Bone Mineral Density and Fracture in Post-Menopausal Osteoporotic Women: a Systematic Review and Meta-Analysis","authors":"Malahat Khalili, A. Hosseinzadeh, Habibollah Mohammadi Kiavandani, N. Khanjani","doi":"10.1007/s12018-018-9241-4","DOIUrl":"https://doi.org/10.1007/s12018-018-9241-4","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"22-32"},"PeriodicalIF":1.8,"publicationDate":"2018-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9241-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42704886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myokine—Irisin—and Its Effects Linking Bone and Muscle Function","authors":"G. Colaianni, G. Brunetti, S. Colucci, M. Grano","doi":"10.1007/s12018-017-9240-x","DOIUrl":"https://doi.org/10.1007/s12018-017-9240-x","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 1","pages":"16-21"},"PeriodicalIF":1.8,"publicationDate":"2018-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-017-9240-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42540496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Fracture Acute Phase Response-A Unifying Theory of Fracture Repair: Clinical and Scientific Implications.","authors":"Courtney E Baker,&nbsp;Stephanie N Moore-Lotridge,&nbsp;Alexander A Hysong,&nbsp;Samuel L Posey,&nbsp;J Patton Robinette,&nbsp;Deke M Blum,&nbsp;Michael A Benvenuti,&nbsp;Heather A Cole,&nbsp;Satoru Egawa,&nbsp;Atsushi Okawa,&nbsp;Masanori Saito,&nbsp;Jason R McCarthy,&nbsp;Jeffry S Nyman,&nbsp;Masato Yuasa,&nbsp;Jonathan G Schoenecker","doi":"10.1007/s12018-018-9256-x","DOIUrl":"https://doi.org/10.1007/s12018-018-9256-x","url":null,"abstract":"<p><p>Bone fractures create five problems that must be resolved: bleeding, risk of infection, hypoxia, disproportionate strain, and inability to bear weight. There have been enormous advancements in our understanding of the molecular mechanisms that resolve these problems after fractures, and in best clinical practices of repairing fractures. We put forth a modern, comprehensive model of fracture repair that synthesizes the literature on the biology and biomechanics of fracture repair to address the primary problems of fractures. This updated model is a framework for both fracture management and future studies aimed at understanding and treating this complex process. This model is based upon the fracture acute phase response (APR), which encompasses the molecular mechanisms that respond to injury. The APR is divided into sequential stages of \"survival\" and \"repair.\" Early in convalescence, during \"survival,\" bleeding and infection are resolved by collaborative efforts of the hemostatic and inflammatory pathways. Later, in \"repair,\" avascular and biomechanically insufficient bone is replaced by a variable combination of intramembranous and endochondral ossification. Progression to repair cannot occur until survival has been ensured. A disproportionate APR-either insufficient or exuberant-leads to complications of survival (hemorrhage, thrombosis, systemic inflammatory response syndrome, infection, death) and/or repair (delayed- or non-union). The type of ossification utilized for fracture repair is dependent on the relative amounts of strain and vascularity in the fracture microenvironment, but any failure along this process can disrupt or delay fracture healing and result in a similar non-union. Therefore, incomplete understanding of the principles herein can result in mismanagement of fracture care or application of hardware that interferes with fracture repair. This unifying model of fracture repair not only informs clinicians how their interventions fit within the framework of normal biological healing but also instructs investigators about the critical variables and outputs to assess during a study of fracture repair.</p>","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"16 4","pages":"142-158"},"PeriodicalIF":1.8,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-018-9256-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37107421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}