Interventional Medicine and Applied Science最新文献_第9页

Establishing methods for isolation of stem cells from human exfoliated deciduous from carious deciduous teeth. 建立人龋乳牙脱落乳牙干细胞分离方法。

Interventional Medicine and Applied Science Pub Date : 2018-03-01 DOI: 10.1556/1646.10.2018.06

Masagus Zainuri, Ratih Rinendya Putri, Endang W Bachtiar

{"title":"Establishing methods for isolation of stem cells from human exfoliated deciduous from carious deciduous teeth.","authors":"Masagus Zainuri, Ratih Rinendya Putri, Endang W Bachtiar","doi":"10.1556/1646.10.2018.06","DOIUrl":"https://doi.org/10.1556/1646.10.2018.06","url":null,"abstract":"Aim: This study aims to establish the isolation method of stem cells from pulp tissue of carious deciduous teeth.Methods: The teeth were soaked in 1% povidone-iodine solution for about 1 min followed by washing in PBS with 1% antibiotic-antimycotic thrice. Dental pulp tissue was removed by extirpation, and then cultivated in the culture medium. Characterization of mesenchymal stem cell (MSC) was carried out using human MSC analysis kit with positive markers CD90, CD73, and CD105, but negative for expressions of CD45, CD34, CD11b, CD19, and HLA-DR. Differentiation capacity of stem cells from human exfoliated deciduous (SHED) was determined by staining with Alizarin S, Alcian Blue, and Oil Red O.Results: There is no contamination after 3 days of culture. SHED derived from dental pulp were expressions of 99.2% of positive marker and 0.3% of the negative marker. At passage 5, SHED was differentiated into osteocyte, chondrocyte, and adipocyte types of cells in the induction medium.Conclusion: SHED derived from carious deciduous teeth can be used as a source of stem cell for regenerative medicine.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"10 1","pages":"33-37"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.10.2018.06","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36619744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

RETRACTION NOTE TO: Therapeutic benefits of phosphodiesterase-5 inhibition in chronic heart failure: A meta-analysis. 摘要:抑制磷酸二酯酶-5治疗慢性心力衰竭的益处:一项荟萃分析。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.0001

Renato De Vecchis, Arturo Cesaro, Carmelina Ariano

引用次数: 0

Oxidative modification of proteins in the process of experimental periodontitis development. 实验性牙周炎发生过程中蛋白质的氧化修饰。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.28

Andrii Demkovych, Yurii Bondarenko, Petro Anatoliyovych Hasiuk

{"title":"Oxidative modification of proteins in the process of experimental periodontitis development.","authors":"Andrii Demkovych, Yurii Bondarenko, Petro Anatoliyovych Hasiuk","doi":"10.1556/1646.9.2017.28","DOIUrl":"10.1556/1646.9.2017.28","url":null,"abstract":"The article reveals patterns of changes in the parameters of oxidative modification of proteins for different periods of the inflammatory process in periodontal tissues during periodontitis. Biochemical researches of phenylhydrazones, aldehyde-, and ketone derivatives of neutral and basic proteins were determined in the blood of white rats on the 7th, 14th, and 30th days of the experimental periodontitis development, as well as in intact animals. The method for determination of the oxidative modification of proteins was based on the interaction of oxidized amino acid residues with 2,4-dinitrophenylhydrazine to form 2,4-dinitrophenylhydrazones. At the early stage of experimental periodontitis development, i.e., on the 7th day, an increase in the products of oxidative modification of proteins of basic and neutral nature was observed in the blood serum, but later, on the 14th day, this index changed in opposite direction, i.e., it began to decrease; however, it was higher relative to the intact group of animals. The obtained factual data evidence that under the conditions of experimental periodontitis formation, there is an intensive increase in the level of oxidative modification of proteins especially in the early period of the inflammatory process development.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"218-221"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.28","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

A rare complication of percutaneous coronary intervention: Coronary pseudoaneurysm formation. 经皮冠状动脉介入治疗的罕见并发症:冠状假性动脉瘤形成。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.33

Oğuzhan Çelik, Lütfü Bekar, Mucahit Yetim, Tolga Doğan, Çağlar Alp, Macit Kalçık, Yusuf Karavelioğlu

引用次数: 1

Nano-colloidal carrier via polymeric coating for oral delivery of isradipine. 通过聚合物涂层制成的纳米胶体载体，用于口服异拉地平。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.25

Vikash Kumar, Hema Chaudhary, Anjoo Kamboj

{"title":"Nano-colloidal carrier via polymeric coating for oral delivery of isradipine.","authors":"Vikash Kumar, Hema Chaudhary, Anjoo Kamboj","doi":"10.1556/1646.9.2017.25","DOIUrl":"10.1556/1646.9.2017.25","url":null,"abstract":"Our research objective was to develop, characterize, and optimize stable form of nano-colloidal carrier with Eudragit-coated solid lipid nanobioparticles (SLNbp) for oral delivery of isradipine (ISR). To achieve, a three factors, i.e., lipid-to-surfactant ratio (A, % w/w), Eudragit L100 (B, % w/w), and sonication time (C, minutes) at three levels (-1 and +1 levels of quality central level) was applied to develop SLNbp using response surface methodology at constant ratio of ISR and rutin. The second-order polynomial quadratic equations of responses [R1, R2, and R3; entrapment efficiency (EE), particle size, and drug release] were constructed and also plotted response surface (two- and three-dimensional) plots. The derived polynomial equation and 2D and 3D model were showed the relationship between the responses of the selected independent variables (A, B, and C). The model validation and optimization was performed by numerical checkpoint analysis to predict the optimized solid lipid nanobioparticle formulas (ONbp 1-10). The optimized formulations prepared and during evaluation ONbp 3 has better smaller particle size (106 nm), sustainable release (95.61% up to 40 h), higher EE (97.85%), and drug content (99.92% ± 0.08%) during 3-month storage showed good stability. Therefore, its performance can be considered for further development of stable oral drug delivery system of ISR.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"222-234"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/c0/imas-09-25.PMC6016206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36263404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A bedside ultrasound technique for fluid therapy monitoring in severe hypovolemia: Tissue Doppler imaging of the right ventricle. 床边超声技术用于严重低血容量的液体治疗监测:右心室的组织多普勒成像。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.23

Erden Erol Unluer, Togay Evrin, Burak Katipoglu, Serdar Bayata

{"title":"A bedside ultrasound technique for fluid therapy monitoring in severe hypovolemia: Tissue Doppler imaging of the right ventricle.","authors":"Erden Erol Unluer, Togay Evrin, Burak Katipoglu, Serdar Bayata","doi":"10.1556/1646.9.2017.23","DOIUrl":"https://doi.org/10.1556/1646.9.2017.23","url":null,"abstract":"Fluid therapy is one of the main issues for hemodynamic resuscitation. Tissue Doppler imaging (TDI) of the right ventricle (RV) with bedside ultrasound (BUS) technique is a new dynamic method to identify fluid responsiveness in patients with hypotension. Here, we present the case of a hypotensive patient monitored with TDI measurements of RV. A 75-year-old male patient was admitted to the emergency department (ED) with the complaint of diarrhea. He was in severe hypovolemia, with hypotension, tachycardia, and tachypnea. His laboratory results were normal. BUS was performed on the patient by the ED physician. The velocity of the excursion of the tricuspid valve measured at presentation was 14.47 cm/s and, together with collapsed inferior vena cava (IVC), this finding led to the decision to begin fluid therapy immediately. The patient underwent 2 L of fluid therapy with 0.9% NaCl in a 2-h period. Control BUS after fluid therapy revealed decreased TDI velocity of tricuspid annulus to 11.81 cm/s and dilated IVC not collapsing sufficiently with respiration. The patient received his maintenance therapy after admission to the internal medicine department and was discharged from the service after 3 days. TDI in fluid responsiveness may find a clinical role in the future by the clinical studies.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"212-214"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.23","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Report on the management of thrombocytopenia in obstetric patients: A retrospective study. 产科患者血小板减少症的处理报告:一项回顾性研究。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.37

Mehri Seifoleslami

引用次数: 0

The effects of resistance and endurance training on risk factors of vascular inflammation and atherogenesis in non-athlete men. 抵抗和耐力训练对非运动员男性血管炎症和动脉粥样硬化危险因素的影响。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.36

Mehdi Mogharnasi, Kazem Cheragh-Birjandi, Sadegh Cheragh-Birjandi, Hossein TaheriChadorneshin

{"title":"The effects of resistance and endurance training on risk factors of vascular inflammation and atherogenesis in non-athlete men.","authors":"Mehdi Mogharnasi, Kazem Cheragh-Birjandi, Sadegh Cheragh-Birjandi, Hossein TaheriChadorneshin","doi":"10.1556/1646.9.2017.36","DOIUrl":"https://doi.org/10.1556/1646.9.2017.36","url":null,"abstract":"Background: Studies show that different types of training have a significant role in reducing both new and traditional risk factors of cardiovascular diseases, and the new risk factors are more sensitive and accurate in predicting such diseases.Objective: The aim of this study was to determine the effects of resistance and endurance exercises on risk factors of vascular inflammation and atherogenesis in non-athlete men.Methods: Thirty-six non-athlete male students (mean age: 20.45 ± 1.20 years; mean body mass index: 23.66 ± 3.65 kg/m2) were randomly assigned into either three groups: control group, resistance training (RT), and endurance training (ET). The training groups exercised for 3 days/week for 8 weeks. ET group performed treadmill-running at 65%-80% of maximum heart rate and with a 16-30 min duration; the task of RT group consisted of three repetition sets, 8-10 per set, at 60%-80% of one repetition maximum, with 2-min recesses. Blood samples were taken before and after the training program. Data were analyzed by Shapiro-Wilk test, one-way ANOVA, LSD test, and dependent t-test (α ≤ 0.05).Results: The results indicated a significant reduction in total cholesterol levels in both RT and ET groups. Also high-density lipoprotein cholesterol significantly increased in both training groups. In addition, following 8 weeks, low-density lipoprotein cholesterol in ET group was significantly decreased, whereas these training methods have had no significant effects on the new cardiovascular biomarkers (hs-CRP, IL-6, and sICAM-1).Conclusion: It seems that both ET and RT with improvement in lipid profiles could be effective in prevention and treatment of the cardiovascular disease.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"185-190"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.36","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36264594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Salivary oxidative analysis and periodontal status in children with atopy. 特应性儿童唾液氧化分析与牙周状况。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.32

Rozana Nazaryan, Liudmyla Kryvenko

{"title":"Salivary oxidative analysis and periodontal status in children with atopy.","authors":"Rozana Nazaryan, Liudmyla Kryvenko","doi":"10.1556/1646.9.2017.32","DOIUrl":"https://doi.org/10.1556/1646.9.2017.32","url":null,"abstract":"Background and aims: Prevalence of atopic diseases is progressively increasing in children with unclear clinical picture in oral cavity. This study aimed to find correlation between the total antioxidant and periodontal status in the saliva of periodontally compromised with atopy.Materials and methods: The groups consisted of patients of atopic diseases and gingivitis (ADG), of atopic diseases without gingivitis (AD), and healthy controls (HC). The level of gingival inflammation was evaluated using the sulcus bleeding index (SBI) reported by Mühlemann and Son. Glutathione (GSH), malondialdehyde (MDA), and superoxide dismutase (SOD) were estimated in saliva.Results: The mean salivary MDA levels of group HC was significantly lower compared with group ADG and AD (P < 0.05). Similarly, in the case of salivary GSH, marker levels revealed a significant decrease (P < 0.05) when mean values in the control group (5.12 ± 0.66 µmol/L) were compared with the ADG (2.31 ± 0.44 µmol/L) and AD groups (2.69 ± 0.56 µmol/L). The SOD activity was significantly lower in the ADG and AD groups compared with HC.Discussion: As there was no significant difference in the level of SOD concentration between groups, we suggest that antioxidant imbalance is primarily explained by atopic disease.Conclusion: The results showed changes in antioxidant balance in children with atopy.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"199-203"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.32","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36264596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Diode laser therapy in the management of chronic periodontitis - A clinico-microbiological study. 二极管激光治疗慢性牙周炎的临床-微生物学研究。

Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.38

Kausar Jaha Yadwad, H R Veena, Sudhir R Patil, B M Shivaprasad

{"title":"Diode laser therapy in the management of chronic periodontitis - A clinico-microbiological study.","authors":"Kausar Jaha Yadwad, H R Veena, Sudhir R Patil, B M Shivaprasad","doi":"10.1556/1646.9.2017.38","DOIUrl":"https://doi.org/10.1556/1646.9.2017.38","url":null,"abstract":"Introduction: Chronic periodontitis (CP) is an infectious disease resulting in inflammation of the supporting tissues of the teeth with progressive attachment loss and bone loss. This study aimed to evaluate the effect of 980-nm diode laser, as an adjunct to scaling and root planing (SRP) in the management of CP.Methodology: A total of 40 systemically healthy subjects diagnosed with CP were randomly assigned into two groups G1 (SRP and sham application of laser) and G2 (SRP and laser irradiation) with equal numbers in each. The levels of Porphyromonas gingivalis (Pg) were estimated from plaque samples using real-time polymerase chain reaction. Clinical and microbiological parameters were assessed at baseline, 4-6, and 12-14 weeks posttreatment in both groups.Results: A gradual reduction in the levels of Pg and improvement in clinical parameters were observed from baseline to 4-6 and 12-14 weeks in both groups. However, the comparison between groups, although clinically relevant, was not found to be statistically significant.Conclusion: Although a 980-nm diode laser may not have any added benefit compared with SRP, it may emerge as an effective non-surgical treatment option in advanced periodontitis with complex inaccessible subgingival niches where comprehensive periodontal care may not be feasible.","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"191-198"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.38","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36264595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16