Interventional Medicine and Applied Science最新文献

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Transvaginal extraction of laparoscopic liver resection specimen. 经阴道腹腔镜肝切除标本提取。
Interventional Medicine and Applied Science Pub Date : 2017-12-01 DOI: 10.1556/1646.9.2017.39
Veysel Ersan, Cuneyt Kayaalp, Aydin Aktas, Ersin Gundogan, Uygar Teomete, Fatih Sumer, Servet Karagul
{"title":"Transvaginal extraction of laparoscopic liver resection specimen.","authors":"Veysel Ersan,&nbsp;Cuneyt Kayaalp,&nbsp;Aydin Aktas,&nbsp;Ersin Gundogan,&nbsp;Uygar Teomete,&nbsp;Fatih Sumer,&nbsp;Servet Karagul","doi":"10.1556/1646.9.2017.39","DOIUrl":"https://doi.org/10.1556/1646.9.2017.39","url":null,"abstract":"<p><p>The application of laparoscopic surgery via the vagina has been introduced at the beginning of this millennium. Here, we report a case of transvaginal extraction of a laparoscopic hepatectomy specimen. An exophytic liver mass originated from segment VI in a 24-year-old female was excised with laparoscopic technique using four trocars (0.5-1.2 cm sizes). The specimen (11 × 8.5 cm) was removed transvaginally instead of an abdominal incision. To the best of our knowledge, only six similar cases have been previously reported, with a patient age range of 32-74 years. Our case, due to younger age, had high cosmetic expectations. Specific to this case, we aimed a better aesthetic outcomes and better convalescence period and, we achieved these objectives. We believe that patient selection and experience on natural orifice specimen extraction were the keys to the success of the operation. We shared this technique with a video presentation.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 4","pages":"215-217"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.39","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Sex differences of odontometrical indexes crowns of molars. 磨牙牙冠口腔测量指标的性别差异。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.08
Petro Hasiuk, Anna Vorobets, Nataliya Hasiuk, Svitlana Rosolovska, Irina Bodnarchuk, Volodymyr Radchuk
{"title":"Sex differences of odontometrical indexes crowns of molars.","authors":"Petro Hasiuk,&nbsp;Anna Vorobets,&nbsp;Nataliya Hasiuk,&nbsp;Svitlana Rosolovska,&nbsp;Irina Bodnarchuk,&nbsp;Volodymyr Radchuk","doi":"10.1556/1646.9.2017.08","DOIUrl":"https://doi.org/10.1556/1646.9.2017.08","url":null,"abstract":"<p><p>Modern reconstructive methods of dentistry (stopping, restoration, and prosthetics with different types of orthopedic constructions) require detailed examination of the anatomical structure of the teeth crowns, especially examination of the knowledge about the relief of masticatory surface. That is why, we conducted a detailed examination of the features of odontoglyphics of molars, according to the sex and determination the odontometrical teeth indices of the citizens of Ternopil region. To achieve the goals, we use the following research methods, such as odontological, odontometrical, and statistical. According to the odontometrical indices of the sizes of the crowns of the molars, women's processes of reduction are reflected more than men's. Sex differences of the crown sizes are specially defined on the second upper and second lower molars. In the result of the conducted researches, it was found and theoretically confirmed racial identity of Ternopil and Ternopil region citizens, and it was given the characteristics of the differences of odontometrical indices of molar crowns of males and females. The lore of these characteristics plays a great role in the clinic of prosthetic dentistry.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"160-163"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.08","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Anatomical and morphological aspects of papillae, epithelium, muscles, and glands of rats' tongue: Light, scanning, and transmission electron microscopic study. 大鼠舌的乳头、上皮、肌肉和腺体的解剖和形态学方面:光、扫描和透射电镜研究。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.21
Ludmila Davydova, Gennadii Tkach, Alexey Tymoshenko, Alexey Moskalenko, Vitalii Sikora, Ludmila Kyptenko, Mykola Lyndin, Dmytro Muravskyi, Olena Maksymova, Olga Suchonos
{"title":"Anatomical and morphological aspects of papillae, epithelium, muscles, and glands of rats' tongue: Light, scanning, and transmission electron microscopic study.","authors":"Ludmila Davydova,&nbsp;Gennadii Tkach,&nbsp;Alexey Tymoshenko,&nbsp;Alexey Moskalenko,&nbsp;Vitalii Sikora,&nbsp;Ludmila Kyptenko,&nbsp;Mykola Lyndin,&nbsp;Dmytro Muravskyi,&nbsp;Olena Maksymova,&nbsp;Olga Suchonos","doi":"10.1556/1646.9.2017.21","DOIUrl":"https://doi.org/10.1556/1646.9.2017.21","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this paper is to describe the research results of the morphological structure of white laboratory rats' tongue at the macro-, micro-, and ultrastructural levels by scanning, light, and transmission electron microscopy.</p><p><strong>Results: </strong>Our results show that the tongue of these rats has a number of unique morphological features that are different from the tongue of other rodents consequently to allow identifying their species-specific features.</p><p><strong>Conclusions: </strong>Our findings have shown the features of the tongue structure of white laboratory rats at micro-, macro-, and ultrascopic levels. The data analysis revealed that mucous membrane of the tongue contains a large number of papillae, such as fungiform, filiform, foliate, vallate, and multifilamentary papillae. Each has a different shape, size, and location. The tongue's morphological feature consists of three types of filiform papillae, well-developed foliate and multifilamentary papillae, as well as one large and similar smaller circumvallate papillae. The muscle of the tongue contains a large number of mitochondria of different shapes and sizes. However, we have received data for a complete picture of structure of this organ that will be useful in further experimental and morphological studies of the white laboratory rats.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"168-177"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.21","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Endothelial nitric oxide synthase gene polymorphisms in patients with slow coronary flow. 冠状动脉慢血流患者的内皮型一氧化氮合酶基因多态性。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.17
Nurzen Sezgin, Abdullah Tekin, Fatma Belgin Atac, Hasibe Verdi, Alpay Turan Sezgin
{"title":"Endothelial nitric oxide synthase gene polymorphisms in patients with slow coronary flow.","authors":"Nurzen Sezgin,&nbsp;Abdullah Tekin,&nbsp;Fatma Belgin Atac,&nbsp;Hasibe Verdi,&nbsp;Alpay Turan Sezgin","doi":"10.1556/1646.9.2017.17","DOIUrl":"https://doi.org/10.1556/1646.9.2017.17","url":null,"abstract":"<p><strong>Background and aims: </strong>The aim of this study was to explore potential associations of the intron 4 variable number of tandem repeats (VNTR) and E298A polymorphisms of the endothelial nitric oxide synthase (eNOS) gene with slow coronary flow (SCF). The association between plasma nitrate and nitrite (NO <i><sub>x</sub></i> ) concentrations and eNOS gene polymorphisms was also assessed.</p><p><strong>Materials and methods: </strong>The intron 4 VNTR and E298A polymorphisms of the eNOS gene were evaluated in the isolated DNA blood samples obtained from the SCF patient group (<i>n</i> = 30) and healthy group consisted of age- and sex-matched controls (<i>n</i> = 61).</p><p><strong>Results: </strong>Plasma NO <i><sub>x</sub></i> level was significantly lower in patients with SCF than in controls. In addition, patients with SCF have significantly lower nitric oxide levels than control subjects within each genotype variants. The allele and genotyped frequencies of the eNOS intron 4 VNTR and E298A polymorphisms were similar between patients with SCF and the controls. Plasma NO <i><sub>x</sub></i> concentrations with respect to the relevant genotypes were found insignificant.</p><p><strong>Discussion and conclusion: </strong>Plasma NO <i><sub>x</sub></i> is lower in patients with SCF than in healthy subjects. Our findings may suggest the lack of association between intron 4 VNTR and E298A polymorphisms of the eNOS gene and SCF.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.17","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35216064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Pathomorphological peculiarities of tuberculous meningoencephalitis associated with HIV infection. 结核性脑膜脑炎与HIV感染的病理形态学特征。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.31
Volodymyr M Kozko, Andriy V Bondarenko, Anatoliy V Gavrylov, Olga S Shevchenko, Vitalii V Gargin
{"title":"Pathomorphological peculiarities of tuberculous meningoencephalitis associated with HIV infection.","authors":"Volodymyr M Kozko,&nbsp;Andriy V Bondarenko,&nbsp;Anatoliy V Gavrylov,&nbsp;Olga S Shevchenko,&nbsp;Vitalii V Gargin","doi":"10.1556/1646.9.2017.31","DOIUrl":"https://doi.org/10.1556/1646.9.2017.31","url":null,"abstract":"<p><strong>Background and aims: </strong>One of the most severe manifestation displays of tuberculosis (TB) generalization is meningitis/meningoencephalitis. The purpose of this work was to improve the diagnostic efficiency of TB central nervous system (CNS) affection in human immunodeficiency virus (HIV)-infected persons.</p><p><strong>Materials and methods: </strong>Meninges and cerebral tissues, taken from died patients, who were HIV-infected and dead from TB of CNS affection, were investigated histologically.</p><p><strong>Results and discussion: </strong>Our examination showed that clinical course of the pathologic process loses the peculiarity of TB-undulating character, and changes in tissues have monomorphism that appears in the presence of the same type of granulomas with a few Pirogov-Langhans cells. Alterative reactions with formation of the large fields of caseous necrosis, necrotic focuses, areas of infiltration with polymorphic cellular elements went out on the first plan in the disorder of cerebrum in patients with the terminal stage of HIV infection. The tendency to decrease in inflammatory-proliferative processes was observed, which is confirmed by the presence of the poorly expressed cellular reaction on the peripheries of focuses of caseous necrosis.</p><p><strong>Conclusion: </strong>Morphologic features of tuberculous meningoencephalitis in HIV-infected patients are the presence of edema, gliosis, trombovasculitis, small focal hemorrhage, tuberculous granuloma formation with a small number of Pirogov-Langhans cells, and the prevalence of alterative-exudative reactions.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"144-149"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.31","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
The interaction effects of resistance training and sustanon abuse on liver antioxidant activities and serum enzymes in male rats. 抗阻训练和磺酸滥用对雄性大鼠肝脏抗氧化活性和血清酶的相互作用。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.29
Hamid Arazi, Siavash Rahmati, Hosein Ghafoori
{"title":"The interaction effects of resistance training and sustanon abuse on liver antioxidant activities and serum enzymes in male rats.","authors":"Hamid Arazi,&nbsp;Siavash Rahmati,&nbsp;Hosein Ghafoori","doi":"10.1556/1646.9.2017.29","DOIUrl":"https://doi.org/10.1556/1646.9.2017.29","url":null,"abstract":"<p><strong>Background: </strong>Anabolic-androgenic steroids (AAS) are synthetic drugs derived from testosterone, the uncontrolled usage of which may lead to serious side effects. Previous studies have shown that resistance training (RT) is the main exercise modality practiced by AAS abusers. Thus, this work was carried out to evaluate the hepatotoxic effects of sustanon (Su) as an example of AAS in trained male rats.</p><p><strong>Methods: </strong>Rats were divided into sedentary/non-Su, sedentary/Su, RT/non-Su, and RT/Su. Su-administration groups received Su 10 mg/kg intramuscularly once a week for 8 weeks. In the 8-week RT, the rats climbed a vertical ladder 3 days/week.</p><p><strong>Results: </strong>After Su administration, the mean values of serum parameters related to hepatic function were within normal ranges. Superoxide dismutase, glutathione peroxidase, and glutathione reductase activities were higher (<i>P < </i>0.05) in the liver of Su-treated rats. Chronic exercise alone did not change any of the above parameters.</p><p><strong>Conclusions: </strong>The present findings suggest that the 8-week injection of Su, either with or without concurrent RT upregulation of enzymatic antioxidant activities and RT, did not attenuate the increase of enzymatic activities due to the Su administration. Furthermore, Su abuse in this dose did not make any severe liver damage.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"178-183"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.29","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Evaluation of ghrelin levels and endothelial functions in patients with coronary slow flow phenomenon. 评估冠状动脉慢流现象患者的胃泌素水平和内皮功能。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.27
Oğuzhan Çelik, Erkan Demirci, Mustafa Aydın, Turgut Karabag, Macit Kalçık
{"title":"Evaluation of ghrelin levels and endothelial functions in patients with coronary slow flow phenomenon.","authors":"Oğuzhan Çelik, Erkan Demirci, Mustafa Aydın, Turgut Karabag, Macit Kalçık","doi":"10.1556/1646.9.2017.27","DOIUrl":"10.1556/1646.9.2017.27","url":null,"abstract":"<p><strong>Background: </strong>Ghrelin has recently been reported to have beneficial effects on cardiac contractile functions and coronary blood flow. The main purpose of this study was to investigate the role of ghrelin in the pathogenesis of coronary slow flow (CSF) together with endothelial functions.</p><p><strong>Methods: </strong>Twenty-five patients having normal coronary arteries with CSF and 25 controls with normal coronary flow were included into the study. The quantitative measurement of coronary blood flow was performed for each coronary artery using the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method. Ghrelin levels were measured using the enzyme-linked immunosorbent assay method from venous blood samples. Endothelial functions were evaluated from the brachial artery with the flow-mediated dilation (FMD) and nitrate-related dilation methods.</p><p><strong>Results: </strong>There was a significant difference in terms of mean TFC values between the control and CSF groups (<i>p</i> < 0.001 for all coronary arteries). The mean FMD percentage among patients with CSF was lower than that of the control group (5.9 ± 0.8 vs. 10.7% ± 1.1%; <i>p</i> < 0.001). A moderate negative correlation was observed between the FMD percentages and the TFCs. There was no relationship between the TFC and ghrelin levels.</p><p><strong>Conclusion: </strong>Plasma ghrelin levels seem to be uninfluential while impaired endothelial functions play an important role in the etiopathogenesis of CSF.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"154-159"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/31/imas-09-03-27.PMC5700701.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of a multicomponent hand hygiene intervention strategy in reducing infection rates at a university hospital in Saudi Arabia. 多成分手部卫生干预策略对降低沙特阿拉伯一所大学医院感染率的影响。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.24
Ahmed Al Kuwaiti
{"title":"Impact of a multicomponent hand hygiene intervention strategy in reducing infection rates at a university hospital in Saudi Arabia.","authors":"Ahmed Al Kuwaiti","doi":"10.1556/1646.9.2017.24","DOIUrl":"10.1556/1646.9.2017.24","url":null,"abstract":"<p><strong>Background and aims: </strong>Few studies have reported the correlation between hand hygiene (HH) practices and infection rates in Saudi Arabia. This work was aimed to study the effect of a multicomponent HH intervention strategy in improving HH compliance and reducing infection rates at King Fahd Hospital of the University, Al-Khobar, Saudi Arabia between January 2014 and December 2016.</p><p><strong>Methods: </strong>A yearlong multicomponent HH intervention, which included various strategies recommended by the World Health Organization, was introduced. HH compliance among staff and infection rates observed in the inpatient wards were assessed and compared at pre- and post-interventional phases.</p><p><strong>Results: </strong>There was a significant increase in mean HH compliance from 50.17% to 71.75% after the intervention (<i>P</i> < 0.05). Hospital-acquired infection (HAI) and catheter-associated urinary tract infection (CAUTI) rates decreased from 3.37 to 2.59 and from 3.73 to 1.75, respectively (<i>P</i> < 0.05). HH compliance was found to be negatively correlated with HAI (<i>r</i> = -0.278) and CAUTI (<i>r</i> = -0.523) rates.</p><p><strong>Conclusions: </strong>Results show that multicomponent intervention is effective in improving HH compliance, and that an increase in HH compliance among hospital staff decreases infection rates. Further studies on cost-effectiveness of such a model could augment to these findings.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"137-143"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/42/4f/imas-09-03-24.PMC5700699.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic benefits of phosphodiesterase-5 inhibition in chronic heart failure: A meta-analysis. 抑制磷酸二酯酶-5治疗慢性心力衰竭的益处:一项荟萃分析。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.26
Renato De Vecchis, Arturo Cesaro, Carmelina Ariano
{"title":"Therapeutic benefits of phosphodiesterase-5 inhibition in chronic heart failure: A meta-analysis.","authors":"Renato De Vecchis,&nbsp;Arturo Cesaro,&nbsp;Carmelina Ariano","doi":"10.1556/1646.9.2017.26","DOIUrl":"https://doi.org/10.1556/1646.9.2017.26","url":null,"abstract":"<p><strong>Background: </strong>Phosphodiesterase-5 inhibitors (PDE5i) have been shown to be beneficial for patients with pulmonary arterial hypertension. However, several studies would have documented a useful effect of PDE5i even for pulmonary hypertension secondary to left-sided chronic heart failure (CHF).</p><p><strong>Methods: </strong>We performed a meta-analysis including randomized controlled trials (RCTs) which had compared PDE5i (mostly sildenafil) and placebo in CHF patients.</p><p><strong>Results: </strong>Fourteen studies enrolling a total of 928 patients were incorporated in the meta-analysis. In heart failure with reduced left ventricular ejection fraction (HFREF), PDE5i, compared to placebo, significantly improved the composite of death and hospitalization (OR = 0.28; 95% CI: 0.10-0.74). They also improved peak VO<sub>2</sub> [difference in means (MD): 3.76; 95% CI: 3.27-4.25], six-minute walking distance test (MD: 22.7 m; 95% CI: 8.19-37.21), and pulmonary arterial systolic pressure (MD: -11.52 mmHg; 95% CI: -15.56 to -7.49). Conversely, in CHF with preserved left ventricular ejection fraction (HFpEF), PDE5i proved not to yield any significant improvement of the investigated outcomes.</p><p><strong>Conclusions: </strong>In HFREF, PDE5i showed beneficial effects on the composite of death and hospitalization, as well as on exercise capacity and pulmonary hemodynamics. Conversely, in HFpEF, no significant clinical, spiroergometric, or hemodynamic improvement was achieved using PDE5i therapy.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"123-135"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35216065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Management of an acute ischemic stroke during thrombolytic treatment in a pregnant patient with prosthetic valve thrombosis. 人工瓣膜血栓形成孕妇溶栓治疗期间急性缺血性卒中的处理。
Interventional Medicine and Applied Science Pub Date : 2017-09-01 DOI: 10.1556/1646.9.2017.30
Macit Kalçık, Mahmut Yesin, Emrah Bayam, Mustafa Ozan Gürsoy, Ahmet Güner, Sabahattin Gündüz, Mehmet Özkan
{"title":"Management of an acute ischemic stroke during thrombolytic treatment in a pregnant patient with prosthetic valve thrombosis.","authors":"Macit Kalçık,&nbsp;Mahmut Yesin,&nbsp;Emrah Bayam,&nbsp;Mustafa Ozan Gürsoy,&nbsp;Ahmet Güner,&nbsp;Sabahattin Gündüz,&nbsp;Mehmet Özkan","doi":"10.1556/1646.9.2017.30","DOIUrl":"https://doi.org/10.1556/1646.9.2017.30","url":null,"abstract":"<p><p>Prosthetic valve thrombosis (PVT) is a life-threatening complication in pregnant women with mechanical prosthetic heart valves. Thrombolytic therapy (TT) has evolved as an effective treatment alternative to surgery, which is associated with very high maternal and fetal mortality and morbidity in these patients. Acute ischemic stroke may rarely occur during TT for PVT. Here, we present a pregnant patient who was complicated with cerebral thromboembolism during TT for PVT and successfully managed with continuation of TT.</p>","PeriodicalId":45181,"journal":{"name":"Interventional Medicine and Applied Science","volume":"9 3","pages":"150-153"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/1646.9.2017.30","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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