Periodico Tche Quimica最新文献

{"title":"DETERMINANTS OF GESTATIONAL DIABETES MELLITUS","authors":"Y. Devi, Rumaisah Abdillah, M. Muthmainnah","doi":"10.52571/PTQ.V18.N37.2021.04_MUTHMAINNAH_PGS_48_56.PDF","DOIUrl":"https://doi.org/10.52571/PTQ.V18.N37.2021.04_MUTHMAINNAH_PGS_48_56.PDF","url":null,"abstract":"Background: Gestational Diabetes Mellitus (GDM) is a glucose tolerance disorder that first appears during pregnancy. GDM can cause a variety of obstetric and perinatal complications for pregnant women and their fetuses. The prevalence of GDM in the city of Surabaya in 2015 amounted to 2.29%, increasing to 3.88% in 2018. Aim: The purpose of this study was to analyze the determinants (family history of diabetes mellitus, BMI, history of birth weight, parity, and the age of the pregnant woman) that influence the GDM. Methods: This research is an analytical study with an observational approach. The research design was carried out using a case-control study. In this study, the number of samples was 36 people, 6 cases, and 30 people as controls, and were taken randomly. The data source obtained from secondary data (medical records of pregnant women) at Mulyorejo Health Center Surabaya. The analysis used in this study was a simple logistic regression test. Results and Discussion: The result showed an effect of a family history of diabetes mellitus (p = 0.035) on the incidence of GDM. Parity was a potential variable (p = 0.077) on the incidence of GDM. Meanwhile, BMI, history of birth weight, and mother's age did not affect the incidence of GDM. Conclusion: Pregnant women with a family history of diabetes who are not balanced with maintaining a good lifestyle can experience complications of developing GDM.","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2021-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70710343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MEASUREMENT OF LEAD CONCENTRATION IN THE BLOOD OF PUBLIC TRANSPORT DRIVERS IN BANDUNG REGENCY, WEST JAVA, INDONESIA","authors":"Farhan Baehaki, Gita Nur Fajriani, Ani Haerani, Suci Rizki Nurul Aeni, Ayu Yunita Sari","doi":"10.52571/ptq.v17.n36.2020.613_periodico36_pgs_598_607.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.613_periodico36_pgs_598_607.pdf","url":null,"abstract":"\u0000As industrial and transportation activities in Bandung Regency are growing rapidly, Indonesia could be at risk of increasing air pollution levels. One of the air pollutants that are very harmful to the body is lead (Pb) generated from industrial activities, mining, vehicle exhaust gas, and dust from the ground. Lead is a heavy metal that is very dangerous for the body because it is carcinogenic with its activity character as an inhibitor in cell metabolism. This study aimed to analyze the concentration of lead in the blood of public transport drivers who are active on the highway every day and are most at risk of being exposed to Pb. Measurement of Pb concentration was carried out using an Atomic Absorption Spectrophotometer (AAS). Blood samples were taken from public transport drivers at Soreang Terminal, Bandung Regency, West Java, Indonesia. The analysis results showed that the average blood lead content of public transport drivers was 1,032 mg/L. The lowest level was 0.889 mg/L, and the highest was 1,200 mg/L. This shows that the lead content in the blood of public transport drivers is already in excess levels (range numbers 0.800-1.200 mg/L) when compared with the threshold for lead in the blood based on the Regulation of the Ministry of Health of the Republic of Indonesia (0.10 - 0.25 mg/L) and the threshold value set by the World Health Organization, which is 0.4 mg/L.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48384688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SPECTROSCOPY STUDY OF MCl2(H2O)n CLUSTER USING AB INITIO CALCULATIONS","authors":"Ahmed M. Sadoon, O. S. Ahmad","doi":"10.52571/ptq.v17.n36.2020.599_periodico36_pgs_584_597.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.599_periodico36_pgs_584_597.pdf","url":null,"abstract":"\u0000The Infrared (IR) spectroscopy of alkali earth halide salt (MX2) complexes with few numbers of water molecules have been investigated for the first time in this work. BeCl2 and MgCl2 are divalent salts and have been incorporated with water as a polar solvent to form complexes of type MX2(H2O)n. The effect of ion size plays a critical rule in the interactions between solvent and solute. Therefore, Beryllium and Magnesium salts with chloride were chosen to explore this difference. The importance of BeCl2 and MgCl2 comes from their several applications in the industry and pharmacy. For instance, BeCl2 is widely used in the industry as a catalysis of Friede-Craft reactions, while the main application of MgCl2 in pharmacy is as hemodialysis and peritoneal dialysis fluids. Three complexes of each BeCl2 and MgCl2 with water, MX2(H2O)n (n=1-3), were studied, and the chemical structures of these complexes have been performed using ab initio calculations. Ab initio calculations were used to predict possible structures, isomers, and their corresponding IR spectra using Second-order Møller-Plesset perturbation theory (MP2) with 6-311++G as a basis sets. The Geometry evaluations, energy searches, vibrational frequency calculations, and the binding energy of each complex were also extracted theoretically. The minimum energy of complexes structures was calculated, and different isomers have been recorded. Ionic hydrogen bonds (IHBs) between the OH in each water molecule and the chloride ion in the MCl2 was proposed to be the main prevalent contribution to the binding between the salt and water. The bond length between the alkaline metal and chlorine showed a significant increase with increasing the attached water molecule as a result of forming the IHB. Also, the infrared vibrational bands of the OH stretching region were recorded for the minimum structures, and dramatic redshift was performed. The formation of contact-ion pair structures in which each solvent molecule forms an ionic hydrogen bond (IHB) to the salt ion-pair (X-M+X-) has been confirmed by the predicted infrared spectra.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47370673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"APPLICATION OF PORTABLE FLYING ROBOTIC SYSTEMS FOR EARLY DETECTION OF AN IGNITION SOURCE","authors":"R. Polyakov","doi":"10.52571/ptq.v17.n36.2020.1098_periodico36_pgs_1083_1098.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.1098_periodico36_pgs_1083_1098.pdf","url":null,"abstract":"\u0000Recently, the development of modern equipment and early detection of ignition sources has become relevant due to many fires and the material and human damage caused by them. This study aimed to develop a method of searching for the ignition source by moving a mobile gas analyzer towards increasing the concentration of carbon monoxide (CO) emitted in the initial stages of fire. According to the simplex and Kiefer method, an algorithm based on the spatial detection method and guaranteed trajectory definition was used to move the mobile gas analyzer towards increasing concentration. The dependence of the engine speed on the supply voltage, the angular speed of the engine with the supply voltage, the tractive force at the wing flap frequency, the supply voltage as well as the energy consumed by the engine during propulsion were calculated. To determine the direction of the azimuth towards the movement of increasing the concentration of CO, an equation was obtained that made it possible to determine the concentration of CO as a function of the distance from the carbon monoxide source. A diagram of the gradient dependence on the distance to the ignition point was plotted, and the number of points on the trajectory on which the CO concentration is measured was determined. One way to further improve early fire detection methods is to use mobile gas analyzers in the ignition source movement and determine their coordinates with the increase in CO concentration. However, further development is restricted due to insufficient research on design methods for mobile gas analyzers, communication analysis between subsystems, and calculation methods based on mathematical models that adequately describe the basic modes of movement of mobile gas analyzers.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49286674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALYSIS OF ENERGY AND WAVE FUNCTIONS AND THE THERMODYNAMICS PROPERTIES OF THE 6-DIMENSIONAL SCHRODINGER EQUATION UNDER DOUBLE RING-SHAPE OSCILLATOR (DRSO) AND MANNING-ROSEN POTENTIALS USING SUSY QM METHOD","authors":"Dedy A. Bilaut, A. Suparmi, C. Cari, S. Faniandari","doi":"10.52571/ptq.v17.n36.2020.580_periodico36_pgs_565_583.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.580_periodico36_pgs_565_583.pdf","url":null,"abstract":"\u0000The exact solutions of the Schrodinger equations (SE) in the D-dimensional coordinate system have attracted the attention of many theoretical researchers in branches of quantum physics and quantum chemistry. The energy eigenvalues and the wave function are the solutions of the Schrodinger equation that implicitly represents the behavior of a quantum mechanical system. This study aimed to obtain the eigenvalues, wave functions, and thermodynamic properties of the 6-Dimensional Schrodinger equation under Double Ring-Shaped Oscillator (DRSO) and Manning-Rosen potential. The variable separation method was applied to reduce the one 6-Dimensional Schrodinger equation depending on radial and angular non-central potential into five onedimensional Schrodinger equations: one radial and five angular Schrodinger equations. Each of these onedimensional Schrodinger equations was solved using the SUSY QM method to obtain one eigenvalue and one wave function of the radial part, five eigenvalues, and five angular wave functions angular part. Some thermodynamic properties such, the vibrational mean energy 𝑈, vibrational specific heat 𝐶, vibrational free energy 𝐹, and vibrational entropy 𝑆, were obtained using the radial energy equations. The results showed that except the 𝑛𝑙1, all increment of angular quantum number decreases the energy values. Increments of all potential parameter increase the energy values. Increment of angular quantum number and potentials parameter increases the amplitude and shifts the wave functions to the left. However, the increment of 𝑛𝑙1, 𝛼, 𝜎, and 𝜌 decrease the amplitude and shift wavefunctions to the right. Moreover, the vibrational mean energy 𝑈 and free energy 𝐹 increased as the increasing value of potentials parameters, where the ω parameter has the dominant effect than the other parameters. The vibrational specific heat 𝐶 and entropy 𝑆 affected only by the 𝜔 parameter, where 𝐶 and 𝑆 decreased as the increase of 𝜔.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44460008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE HISTOCHEMICAL AND HISTOMORPHOMETRICAL STUDY OF ESOPHAGUS STRUCTURES IN SHEEP (Ovis aries) AND RABBITS (Oryctolagus Cuniculus)","authors":"H. J. Mohammad, Ali Khalaf Ali, Zainab Abdul Jabbar Ridha Al Ali","doi":"10.52571/ptq.v17.n36.2020.472_periodico36_pgs_457_475.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.472_periodico36_pgs_457_475.pdf","url":null,"abstract":"\u0000Evolution between animals causes many changes so that it can adapt to its environments. Each species has unique features that help them survive and can consume different types of food. Sheep and rabbits are economically important animals and used in many aspects of veterinary medicine.This study aimed to compare the histomorphometric and histochemical features of the esophagus of twenty sheep (n = 10) and rabbit (n = 10) adult males. The samples were collected from slaughterhouse and market Misan and were used for histological studies of two types of stains, hematoxylin and eosin, and special stains (Periodic acid Schiff stains). Histological study showed differences in the type epithelium of mucosa lining the esophagus between sheep and rabbits. The epithelium lining was composed of a keratinized stratified squamous epithelium in sheep while in rabbit was composed of a non-keratinized stratified squamous. In both animals, the submucosa layer does not possess glands. The muscular layer of both was composed of striated muscle in the cervical, thoracic, and abdomen parts of the esophagus. Both animals contained an outer layer of loose connective tissue called the adventitia. All layers in sheep showed more thickness than in rabbits. The histochemical study showed that the reaction to Periodic acid Schiff stain was similar between the animals and in different places. Only stratum corneum cells of the sheep mucosa and squamous cells of the rabbit mucosa demonstrated a strong reaction to this stain. In contrast, the rest of the cells of the mucosa and muscular layers were moderate reactions with Periodic acid Schiff stain in all regions sheep and rabbit esophagus. Submucosa and adventitia showed weakly reaction with Periodic acid Schiff's stain in both animals. In conclusion, this study showed that sheep and rabbits have similarities and differences in the esophagus; that is, the layers of this organ has different thicknesses and respond differently to Periodic acid Schiff stain.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49658462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MULTI-POINTED FIELD-EMISSION CATHODE AS A GENERATOR OF HIGHFREQUENCY OSCILLATIONS","authors":"Sergei N. Bratanovskii, Yerdos Amankulov, I. Medvedev","doi":"10.52571/ptq.v17.n36.2020.557_periodico36_pgs_542_553.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.557_periodico36_pgs_542_553.pdf","url":null,"abstract":"\u0000Semiconductor field-emission cathodes have gained considerable popularity in modern radio electronics and electronic optics due to the high-power generation of the electron beam in the external electric field at temperatures close to the room ones. However, their wide application is restricted by the high dependence of the electron emission current on the value of the applied field and geometrical parameters of the cathode. This study aimed to examine the effect of resonance processes on amplifying the field emission of the multi-pointed semiconductor cathode. Modeling the behavior of resonant tunneling of electrons from semiconductors to vacuum was simulated by solving the one-dimensional Schrodinger’s equation, and the amplification due to resonant processes was estimated. The modeling results showed that as the electric field increases, the resonance conditions shift towards low energy levels. With the increase in the width of the barrier for the electron inside the solid body, the resonance conditions shift towards higher energies. It has been established that in onedimensional semiconductors with electrons of low conductivity width, the resonant energy coincides with the Fermi level. These cathode properties are optimal for amplifying the emission current and reducing failures of vacuum electronic devices based on semiconductive field cathodes. The proposed technique can be used to study the regularities of emission amplification due to resonant processes in multipoint semiconductor cathodes with multilayered structure and with metal tips.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48378957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF CONTENTS OF STRUCTURAL CARBOHYDRATES AND LIGNIN OF PERENNIAL FODDER HERBAGES DEPENDING ON VEGETATIVE STAGE GROWTH","authors":"H. K. Khudyakova, A. Shitikova, N. V. Zarenkova, O. V. Kukharenkova, A. V. Konstantinovich","doi":"10.52571/ptq.v17.n36.2020.1009_periodico36_pgs_994_1003.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.1009_periodico36_pgs_994_1003.pdf","url":null,"abstract":"\u0000The purpose of this study is to evaluate cereal grasses – Bromus inermis, Festuca pratensis, Phleum pratense, and legumes: Trifolium pratense, Medicago varia in terms of their content of acid-detergent fibre (ADF), neutral detergent fibre (NDF), acid-detergent lignin (ADL) and hemicellulose (HC), cellulose depending on phases of vegetation – grasses: at vegetative, earing and flowering; legumes– vegetative. It was found that as the herbs grow, an increase in all fractions of the cell walls of leguminous herbs is observed, the cell walls occupy a smaller fraction of dry matter than in grasses, due to the lower HC content in them –10-12%, compared with 25-30% in grasses. The contents of ADF, NDF and ADL (% of dry matter) in grasses prior earing are 31-31, 50-55, 4-6: in earing – 32-37, 55-65, 5-6; in flowering – 40-45, 65-70 and 70-72, 7-9, respectively. Legumes have a higher content of ADL. As plants grow, the relative proportion of ADF in NDF increases, but it does not exceed 50% in grasses. In legumes – 70-80% regardless of the growth phase, explains the lower digestibility of legumes than grasses. To judge the levels of ADF and NDF in herbs, depending on the content of crude fibre (CF), the corresponding regression equations were calculated for grasses and feed prepared from them. The relationship between CF and ADF was closer (n = 64, s = 2.4%, r = 0.93) than between CF and ADL (n = 64, s = 4.4%, r = 0.87). Based on these studies and generalisation of the literature data, ADF and NDF in hay and haylage standard are recommended.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48661690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SYNTHESIS AND ANTITUMOR ACTIVITY OF NEW MULTIFUNCTIONAL COUMARINS","authors":"M. K. Bashir, Yasser Fakri Mustafa, M. Oglah","doi":"10.52571/ptq.v17.n36.2020.886_periodico36_pgs_871_883.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.886_periodico36_pgs_871_883.pdf","url":null,"abstract":"\u0000Cancer constitutes one of the most severe public health menaces worldwide. It is imperative to synthesize new compounds and explore their antitumor activity to find a potential resolution to this health problem. Synthesis of new scaffolds and evaluating their antitumor activity is a relevant approach for combating cancer development. Coumarins can exhibit diverse biological activities, and one of these is the antitumor activity. This study aimed to synthesize new coumarins by grafting their precursors to the aromatic amines via Schiff base formation and evaluating their introductory antitumor activity. New multifunctional coumarins (MC1-MC9) were prepared by integrating a functionalized coumarin with different toluidine derivatives via a Schiff-base linkage. Spectral characterization inspired by FTIR, 1H- and 13C- NMR spectroscopies has established the chemical structures of the synthesized products. The antitumor activity was explored in vitro versus four dominant human cancer lines, including HeLa, SKG, MCF-7, and AMN3. The outcomes acquired from the cell viability assay inspected by applying MTT dye have revealed that the synthesized multifunctional coumarins, particularly MC3, have a hopeful activity. It can be concluded that a similar trend of activity against the test cell lines was observed for the synthesized coumarins, with the best action being versus MCF-7 and the least one versus AMN3. This study not only affords a new scaffold of a significant antitumor activity but also provides some insights into its structureactivity relationship.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47121458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHANGE IN BLOOD CHEMISTRY, PRO-INFLAMMATORY CYTOKINES, AND APOPTOTIC GENES FOLLOWING METHAMPHETAMINE USE IN EXPERIMENTAL RATS","authors":"Z. Goudarzi, S. Hoseini, D. Mehrabani, S. Hashemi","doi":"10.52571/ptq.v17.n36.2020.1163_periodico36_pgs_1147_1159.pdf","DOIUrl":"https://doi.org/10.52571/ptq.v17.n36.2020.1163_periodico36_pgs_1147_1159.pdf","url":null,"abstract":"\u0000Methamphetamine (METH) is a globally heavily abused illicit substance with epidemic levels worldwide. This study aimed to investigate changes in blood chemistry and pro-inflammatory cytokines following methamphetamine use in experimental rats. A total of forty-five female rats were randomly devoted to three equal groups of experimental receiving METH subcutaneously (0.4 mg/kg, in 0.6 mL volume) for 21 days, sham received similarly 0.6 mL normal saline, and the control received 0.6 mL distilled water, identically. The elevated plus-maze test was used to confirm cognitive and anxiety changes following METH use until three weeks. Blood chemistry and inflammatory cytokines were evaluated after METH use until 21 days. The results showed an increase in anxiety. The serum levels of transforming growth factor-beta (TGF-β), interleukins of IL-15, IL-17, and adenosine deaminase xanthine oxidase levels were noted. However, white blood cell (WBC) count demonstrated a decreasing trend. There were no other changes in blood chemistry after METH use. It could be observed, however, that methamphetamine increases anxiety and makes some changes in blood chemistry and pro inflammatory cytokines. This study can help make better decisions about the prevention and even treatment of people taking methamphetamine.\u0000","PeriodicalId":45103,"journal":{"name":"Periodico Tche Quimica","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42280107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}