Kevin Wenzel, Julia Thomas, Michael S Davis, Maria Saenko, Matthew J Ervin, Praveena Machineni, Lauren Rudin, Marc Fishman
{"title":"An uncontrolled pilot trial of a buprenorphine dispensing device to enhance outpatient treatment for opioid use disorder.","authors":"Kevin Wenzel, Julia Thomas, Michael S Davis, Maria Saenko, Matthew J Ervin, Praveena Machineni, Lauren Rudin, Marc Fishman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Buprenorphine is an efficacious and widely used pharmacological treatment for OUD; however, barriers to daily adherence and regular monitoring limit its overall effectiveness. The purpose of this study was to test the feasibility of an investigational medication dispensing device to promote adherence and monitoring of daily sublingual buprenorphine for individuals with opioid use disorder (OUD).</p><p><strong>Methods: </strong>This single-arm pilot study recruited (N=25) adults aged 18-65 who were prescribed sublingual buprenorphine for OUD from two outpatient treatment centers in Maryland, USA. All participants were assigned to the investigational buprenorphine dispensing device (MedicaSafe) on top of usual care for a 4-week intervention period. Devices were individually programed to dispense the daily prescribed dosage and given to participants at a baseline visit after providing informed consent. Follow-up visits occurred at 2-weeks and 4-weeks (end of intervention) to collect a urine drug screen (UDS) and self-report questionnaires on opioid use, opioid, craving, global impression of change, and treatment satisfaction. Data from the devices were synced to an online portal resulting in a detailed timeline of the medication dispensation.</p><p><strong>Results: </strong>Participants were mostly White, used heroin, had mean age of 34.1 years, and had been maintained on buprenorphine for an average of 48 weeks prior to study participation. The primary outcome of buprenorphine adherence rate was 92% and was calculated using data from device dispensation logs. Overall patient satisfaction with the device was <i>M</i>=4.67 on a 0-6 scale with higher scores indicating greater satisfaction.</p><p><strong>Conclusions: </strong>Overall, the MedicaSafe platform is a feasible and innovative approach for individuals on daily sublingual buprenorphine for OUD with the potential to improve buprenorphine adherence.</p>","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"25 5","pages":"7-11"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13178509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of vitamin D on chronic obstructive lung disease (COPD): a systematic review","authors":"S. M. Ahmed","doi":"10.1183/23120541.lsc-2022.105","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.105","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"59 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87655042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-COVID: The multimodal path to the right treatment strategy","authors":"D. Gagiannis, Annika Czech, K. Steinestel","doi":"10.1183/23120541.lsc-2022.80","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.80","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"13 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87156670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Allouche, J. Ben Amar, Khaoula Hemissi, Khadija Echi, E. Ben Jemia, H. Zaibi, H. Aouina
{"title":"Obesity and its implications for COVID-19 evolution in Tunisian population","authors":"A. Allouche, J. Ben Amar, Khaoula Hemissi, Khadija Echi, E. Ben Jemia, H. Zaibi, H. Aouina","doi":"10.1183/13993003.congress-2021.pa304","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa304","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"12 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91080548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soumaya Debiche, I. Sahnoun, A. Ben Mansour, Asma Zaafouri, S. Ben Sassi, S. Ben Saad, Fatma Ezzahra Dabbebi, H. Daghfous, S. Maȃlej, F. Tritar, L. Douik El Gharbi
{"title":"Clinical characteristics and outcomes of hospitalized COVID-19 pneumonia : impact of gender","authors":"Soumaya Debiche, I. Sahnoun, A. Ben Mansour, Asma Zaafouri, S. Ben Sassi, S. Ben Saad, Fatma Ezzahra Dabbebi, H. Daghfous, S. Maȃlej, F. Tritar, L. Douik El Gharbi","doi":"10.1183/13993003.congress-2021.pa298","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa298","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"17 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80766278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Johnsen, Stefanie Sattler, K. Miskowiak, K. Kunalan, A. Victor, L. Pedersen, Helle Frost Andreassen, Barbara Jolanta Jørgensen, H. Heebøll, Michael Brun Andersen, L. Marner, C. Hædersdal, H. Hansen, S. Ditlev, C. Porsbjerg, T. Lapperre
{"title":"Multi-disciplinary approach to Long COVID in hospitalised and non-hospitalised COVID-19 patients (IMPACT-COVID study)","authors":"S. Johnsen, Stefanie Sattler, K. Miskowiak, K. Kunalan, A. Victor, L. Pedersen, Helle Frost Andreassen, Barbara Jolanta Jørgensen, H. Heebøll, Michael Brun Andersen, L. Marner, C. Hædersdal, H. Hansen, S. Ditlev, C. Porsbjerg, T. Lapperre","doi":"10.1183/13993003.congress-2021.oa4188","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa4188","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"14 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83538359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Ravaglia, S. Piciucchi, S. Oldani, L. Bertolovic, S. Bensai, C. Colinelli, S. Simoncelli, C. Ghirotti, S. Puglisi, L. Donati, G. Ravaglia, F. Landi, M. Terzitta, V. Poletti
{"title":"Treatment With Baricitinib for Patients With COVID-19 Infections: A Case-Series Study","authors":"C. Ravaglia, S. Piciucchi, S. Oldani, L. Bertolovic, S. Bensai, C. Colinelli, S. Simoncelli, C. Ghirotti, S. Puglisi, L. Donati, G. Ravaglia, F. Landi, M. Terzitta, V. Poletti","doi":"10.1183/13993003.congress-2021.pa454","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa454","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"50 6 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79836984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial Pneumonias: Before and after the COVID-19 pandemic","authors":"K. Ur Rehman, P. Sivakumar","doi":"10.1183/13993003.congress-2021.pa289","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa289","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"38 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84153744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Nwagboso, B. Ekeng, E. Ochang, J. Eze, C. Echieh, S. Ogbudu, A. Etiuma, O. Bassey
{"title":"Analysis of the microbial profile and antimicrobial resistant pattern of empyema thoracis","authors":"C. Nwagboso, B. Ekeng, E. Ochang, J. Eze, C. Echieh, S. Ogbudu, A. Etiuma, O. Bassey","doi":"10.1183/13993003.congress-2021.pa3126","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3126","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"8 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84155232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Calancea, S. Matcovschi, I. Sîrbu, Nina Chicu, V. Chihai, V. Cascaval, T. Dumitras
{"title":"COVID-19: pneumonia and comorbidities at three sites of medical care","authors":"V. Calancea, S. Matcovschi, I. Sîrbu, Nina Chicu, V. Chihai, V. Cascaval, T. Dumitras","doi":"10.1183/13993003.congress-2021.pa291","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa291","url":null,"abstract":"","PeriodicalId":45101,"journal":{"name":"Heroin Addiction and Related Clinical Problems","volume":"9 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73113188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}