Nano Life最新文献_第7页

Periodontitis: Clinical Aspects, Pathophysiology, Experimental Approaches and Emerging Therapies 牙周炎：临床方面、病理生理学、实验方法和新兴疗法

IF 0.8

Nano Life Pub Date : 2021-07-16 DOI: 10.1142/S1793984421300065

Y. H. Kang, F. Berthiaume

引用次数: 0

Kappa-Carrageenan Crosslinked Magnetic Folic Acid-Conjugated Chitosan Nanocomposites for Arginase Encapsulation, Delivery and Cancer Therapy 卡帕-卡拉胶交联磁性叶酸共轭壳聚糖纳米复合材料用于精氨酸酶包封、递送和癌症治疗

IF 0.8

Nano Life Pub Date : 2021-06-28 DOI: 10.1142/s1793984421400055

Rahman Moradi, R. Mohammadzadeh, A. Akbari

引用次数: 3

Nanosized Gadoliniumorthoferrite-based Electrochemical Sensor for the Determination of Dopamine 纳米钆-偏铁氧体电化学传感器测定多巴胺

IF 0.8

Nano Life Pub Date : 2021-06-28 DOI: 10.1142/s1793984421500021

S. Pramanik, Y. Kumar, P. Karmakar, D. Das

{"title":"Nanosized Gadoliniumorthoferrite-based Electrochemical Sensor for the Determination of Dopamine","authors":"S. Pramanik, Y. Kumar, P. Karmakar, D. Das","doi":"10.1142/s1793984421500021","DOIUrl":"https://doi.org/10.1142/s1793984421500021","url":null,"abstract":"This work deals with the synthesis, characterization of gadolinium ferrite nanoparticles, and its use as an electrochemical sensor for detection of dopamine. For the synthesis of gadolinium ferrite nanoparticles (GdFeO3 NPs), the combustion technique was employed using gadolinium oxide and ferric nitrate as precursor materials with sugar and ethanolamine as fuel. The size, shape and morphology of nanomaterials were determined by field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The crystallite size of synthesized nanoparticles was found to be in the range of 40–45[Formula: see text]nm with a cubic crystal system. The electrochemical sensor, GdFeO3 NPs@graphite paste (GdFeO3/GP), was prepared by using synthesized nanomaterials and graphite powder by mixing in mortar in 1:4 ratio. cyclic voltammetry (CV) and Differential pulse voltammetry (DPV) techniques were employed to assess the electrochemical properties of the developed sensor. The result indicated that the developed sensor possessed better sensing ability, where minimum detection limit of dopamine at GdFeO3/GP electrode was 700[Formula: see text]nM with linearity range from 5[Formula: see text][Formula: see text]M to 160[Formula: see text][Formula: see text]M.","PeriodicalId":44929,"journal":{"name":"Nano Life","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47165695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Conductive Nanomaterials used in Bioinks for 3D Bioprinting 用于3D生物打印的生物墨水的导电纳米材料

IF 0.8

Nano Life Pub Date : 2021-06-09 DOI: 10.1142/S1793984421300053

Sheba Goklany

引用次数: 0

Application of Early Warning Nursing System During COVID-19 Epidemic in Children’s Hospital 新型冠状病毒肺炎疫情预警护理系统在儿童医院的应用

IF 0.8

Nano Life Pub Date : 2021-06-05 DOI: 10.1142/S1793984421400043

Wenying Yao, Jin-Xia Yang, Xin Wang, Min Shen

{"title":"Application of Early Warning Nursing System During COVID-19 Epidemic in Children’s Hospital","authors":"Wenying Yao, Jin-Xia Yang, Xin Wang, Min Shen","doi":"10.1142/S1793984421400043","DOIUrl":"https://doi.org/10.1142/S1793984421400043","url":null,"abstract":"Aim: To develop a nursing early warning system in children’s hospital during the outbreak of the novel coronavirus pneumonia, and to accomplish the construction and application of this system, so as to provide decision-support of the prevention and control for COVID-19 in children’s medical institutions. Method: Children’s hospital nursing early warning system was divided into three modules: hospital nursing early warning platform includes internal and external early warning platform, nursing staff early warning program includes protection, human resources early warning plan and patient early warning program includes outpatient, emergency and ward early warning plan. The data of epidemic training, assessment, prevention and control screening from January to June 2020 were collected from the nursing early warning system to evaluate the application effect of the system. Results: A total of 18 procedures and specifications were formulated, nine hospital-level trainings and about 1000 department-level trainings were organized, two hospital-level assessments (pass rate 95.6% and 98.2%), and 78 nurses were reserved, and 10 popular science articles, five popular science videos were published during the application of the nursing early warning system. A total of 583,435 children and 139,308 caregivers were screened in outpatient, emergency and wards during pre-checks, 2385 suspected cases of novel coronavirus pneumonia were confirmed (0.41%) after the screening and 1 case (0.0002%) was finally confirmed. Conclusion: The nursing early warning system of children’s hospital can prevent and control the novel coronavirus pneumonia epidemic from each module, ensure early warning and triage of suspected infected patients, reduce the risk of cross-infection in hospital and improve the safety of the children’s hospital medical environment.","PeriodicalId":44929,"journal":{"name":"Nano Life","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48638413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Intratumoral Photosensitizer Delivery and Photodynamic Therapy. 肿瘤内光敏剂传递和光动力治疗。

IF 0.8

Nano Life Pub Date : 2021-06-01 Epub Date: 2021-06-09 DOI: 10.1142/s179398442130003x

Chen-Hua Ma, Jeffrey Yang, Jenna L Mueller, Huang-Chiao Huang

{"title":"Intratumoral Photosensitizer Delivery and Photodynamic Therapy.","authors":"Chen-Hua Ma, Jeffrey Yang, Jenna L Mueller, Huang-Chiao Huang","doi":"10.1142/s179398442130003x","DOIUrl":"https://doi.org/10.1142/s179398442130003x","url":null,"abstract":"<p><p>Photodynamic therapy (PDT) is a two-step procedure that involves the administration of special drugs, commonly called photosensitizers, followed by the application of certain wavelengths of light. The light activates these photosensitizers to produce reactive molecular species that induce cell death in tissues. There are numerous factors to consider when selecting the appropriate photosensitizer administration route, such as which part of the body is being targeted, the pharmacokinetics of photosensitizers, and the formulation of photosensitizers. While intravenous, topical, and oral administration of photosensitizers are widely used in preclinical and clinical applications of PDT, other administration routes, such as intraperitoneal, intra-arterial, and intratumoral injections, are gaining traction for their potential in treating advanced diseases and reducing off-target toxicities. With recent advances in targeted nanotechnology, biomaterials, and light delivery systems, the exciting possibilities of targeted photosensitizer delivery can be fully realized for preclinical and clinical applications. Further, in light of the growing burden of cancer mortality in low and middle-income countries and development of low-cost light sources and photosensitizers, PDT could be used to treat cancer patients in low-income settings. This short article introduces aspects of interfaces of intratumoral photosensitizer injections and nano-biomaterials for PDT applications in both high-income and low-income settings but does not present a comprehensive review due to space limitations.</p>","PeriodicalId":44929,"journal":{"name":"Nano Life","volume":"11 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412167/pdf/nihms-1724482.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39385977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effect of Aspirin and Statins on Pulmonary Function and Inflammation in Patients with AECOPD 阿司匹林和他汀类药物对AECOPD患者肺功能和炎症的影响

IF 0.8

Nano Life Pub Date : 2020-02-13 DOI: 10.21203/rs.2.23404/v1

Guangqing Duan, Kaixuan Lv, Juncheng Lyu, N. Tian, Lichun Zhang, Qi Liu, Mengjie Wang, Shiyu Sun, Jielun Yu, G. Guo, Wei Tan, Nana Yang

{"title":"Effect of Aspirin and Statins on Pulmonary Function and Inflammation in Patients with AECOPD","authors":"Guangqing Duan, Kaixuan Lv, Juncheng Lyu, N. Tian, Lichun Zhang, Qi Liu, Mengjie Wang, Shiyu Sun, Jielun Yu, G. Guo, Wei Tan, Nana Yang","doi":"10.21203/rs.2.23404/v1","DOIUrl":"https://doi.org/10.21203/rs.2.23404/v1","url":null,"abstract":"Background: The influence of coronary atherosclerosis and related treatment drugs on acute exacerbation of chronic obstructive pulmonary disease (AECOPD) development requires in-depth study. The study investigated the effect of coronary artery calcification (CAC) and drugs for CAC on the development of AECOPD. Methods: This retrospective clinical study recruited subjects with AECOPD from May 2017 to May 2019. All subjects performed spirometry and coronary computed tomography (CT), and were divided into three groups according to whether coronary CT revealed CAC and whether they had received oral aspirin and statins: AECOPD group, AECOPD[Formula: see text]CAC nonmedication and AECOPD[Formula: see text]CAC medication. The t-test and nonparametric test were used for analyzing the lung function, arterial blood gas, routine blood and lipid between groups. Results: Compared with the AECOPD group, Lym% were significantly higher ([Formula: see text]) in both the AECOPD[Formula: see text]CAC nonmedication and the AECOPD[Formula: see text]CAC medication. The AECOPD[Formula: see text]CAC medication group also had significantly higher PaO2 ([Formula: see text]). WBC, Neu, and Neu% in the AECOPD[Formula: see text]CAC medication group were significantly lower ([Formula: see text]) compared to the AECOPD group. Conclusions: Aspirin and statins for the treatment of cardiovascular diseases may be linked to improving lung function, normalizing blood gas levels, and reducing inflammation in patients with AECOPD and CAC. Further, randomized controlled trials are needed to explore this topic.","PeriodicalId":44929,"journal":{"name":"Nano Life","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2020-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44477917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Mechanisms Underlying Therapeutic Benefits of Stem Cell for Heart Failure 干细胞治疗心力衰竭的潜在机制

IF 0.8

Nano Life Pub Date : 2019-09-19 DOI: 10.1142/S1793984419410046

X. Xiong, F. Savira, Kevin W. Huang, Zuoren Yu, B. Wang

引用次数: 0

Advances of Stem Cell Therapy to Treat Heart Failure 干细胞治疗心力衰竭的研究进展

IF 0.8

Nano Life Pub Date : 2019-09-19 DOI: 10.1142/S1793984419410022

Yan-bin Fu, Zhiying He, Chao Zhang

引用次数: 1

Cell Therapy and 3D Regenerative Tissue to Remodel Heart Failure 细胞疗法和3D再生组织重塑心力衰竭

IF 0.8

Nano Life Pub Date : 2019-09-19 DOI: 10.1142/S1793984419410010

Tianxiao Mei, Wenjun Le, H. Cao, Zhan Wang, Wenjie Tang, Zhongmin Liu, Donglu Shi

{"title":"Cell Therapy and 3D Regenerative Tissue to Remodel Heart Failure","authors":"Tianxiao Mei, Wenjun Le, H. Cao, Zhan Wang, Wenjie Tang, Zhongmin Liu, Donglu Shi","doi":"10.1142/S1793984419410010","DOIUrl":"https://doi.org/10.1142/S1793984419410010","url":null,"abstract":"Heart failure (HF) remains the major cause of morbidity and mortality in the world with an alarming rapid rise in heart diseases. Myocardial infarction (MI), depriving of blood flow to the heart muscle, causes myocardial necrosis and apoptosis resulting in decrease of myocardial quantity and ventricular remodeling, which is the main cause of HF. As mature cardiomyocytes (CMs) are incapable of differentiation and proliferation, cardiomyocytes damage is not likely to be reversed. Recent research has advanced to the point where damaged CMs or myocardium can be repaired by exogenous cells or artificial tissue. This review provides the most up-to-date information on the current status of cell therapy and tissue three-dimensional (3D) bioprinting for the treatment of HF. Requirements on 3D printing of biomaterials will be provided including biophysical properties, biocompatibility and biodegradable absorption in vivo that are key factors on the survival and proliferation of transplanted cells in the MI area. Also discussed are the current challenges in cell-based HF therapies and future perspectives in clinical applications.","PeriodicalId":44929,"journal":{"name":"Nano Life","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1142/S1793984419410010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64072681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1