Indian Journal of Sexually Transmitted Diseases and AIDS最新文献

{"title":"A case report of genital Crohn's disease with a brief review of Indian cases reported.","authors":"Mahendra M Kura, Sakshi Santosh Malpani, Isha Kiran Kane","doi":"10.4103/ijstd.ijstd_55_23","DOIUrl":"10.4103/ijstd.ijstd_55_23","url":null,"abstract":"<p><p>Crohn's disease (CD) is a type of inflammatory bowel disease, which presents with extraintestinal manifestations in some cases, skin being one of the organs involved. Vulvar and perianal involvement leads to significant morbidity and has an adverse effect on the quality of life. We report a case of genital CD affecting the vulva, perianal region, and oral cavity, due to its rarity and diagnostic difficulty.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"54-58"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An infant with acral peeling of skin: A curious case of congenital syphilis.","authors":"Rashid Shahid, Swetalina Pradhan, Gaurav Dash","doi":"10.4103/ijstd.ijstd_15_24","DOIUrl":"10.4103/ijstd.ijstd_15_24","url":null,"abstract":"<p><p>Congenital syphilis (CS) is a vertically transmitted infection caused by the spirochete <i>Treponema pallidum</i>. It is seen rarely due to proper antenatal screening. Signs and symptoms appear within the first 2 years of life in early CS and after 2 years in late CS. Failure to diagnose and treat CS in its early stages can result in higher morbidity and mortality. Skin manifestations can guide toward the diagnosis of CS at an early stage. Here, we report a 2-day-old neonate who presented with acral peeling of skin along with respiratory distress and hepatosplenomegaly. Clinical suspicion of CS was made and subsequently confirmed by a positive venereal disease research laboratory test in both mother and child. The child was treated with aqueous crystalline penicillin G as per the CDC guidelines.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"67-69"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IJSTD editorial.","authors":"Rajesh Rajagopalan","doi":"10.4103/ijstd.ijstd_53_24","DOIUrl":"https://doi.org/10.4103/ijstd.ijstd_53_24","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"1"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra-meatal urethral warts: Clinical and dermatoscopic perspectives.","authors":"Prakhar Srivastava, Prachi Srivastava, Niti Khunger","doi":"10.4103/ijstd.ijstd_17_23","DOIUrl":"10.4103/ijstd.ijstd_17_23","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"85-86"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to \"Trends in genital ulcer disease: An observational study at a tertiary care teaching hospital\".","authors":"Ishita Kaushal, Tarun Narang, Bhushan Kumar","doi":"10.4103/ijstd.ijstd_18_24","DOIUrl":"10.4103/ijstd.ijstd_18_24","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"90-91"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual duo: Immunodeficiency disorder and scleroderma.","authors":"Ishwarya Ramadoss, PonniahSubramanian ArulRajamurugan, Mythili Seetharaman Varadhan, Ramesh Ramamoorthy, S Vishnu Priya","doi":"10.4103/ijstd.ijstd_63_23","DOIUrl":"10.4103/ijstd.ijstd_63_23","url":null,"abstract":"<p><p>A 45-year-old woman on treatment for HIV infection with highly active antiretroviral therapy for the past 10 years presented to us with a history of Raynaud's phenomenon and hyperpigmentation of the skin for 2 years. She was diagnosed to have pulmonary arterial hypertension 8 months ago. On examination, she had salt-and-pepper pigmentation and sclerodactyly. Her biochemical workup was normal. She had positive antinuclear antibody by indirect immunofluorescence method. Skin biopsy was consistent with systemic sclerosis. HIV has its own musculoskeletal manifestations. The paradox of autoimmunity in the background of immunodeficiency was intriguing. Treating autoimmunity in the presence of immunodeficiency was challenging. The attribution and differentiation of pulmonary hypertension were difficult. There has been a homology identified between human immunodeficiency virus 1 (HIV 1) and centromere B protein (CENP B). This case is reported because of the unusual occurrence of systemic sclerosis in an HIV patient.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"52-54"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follmann balanitis - A very rare presentation of primary syphilis.","authors":"Sankaranantham Murugan","doi":"10.4103/ijstd.ijstd_39_24","DOIUrl":"https://doi.org/10.4103/ijstd.ijstd_39_24","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"93"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional study of the factors influencing adherence to antiretroviral therapy among adults with human immunodeficiency virus infection in a tertiary care hospital in Puducherry, India.","authors":"Settipalli Surendereddy, M Vijaikumar, Ramesh Jayaraman, P Kavita Vasudevan","doi":"10.4103/ijstd.ijstd_50_23","DOIUrl":"10.4103/ijstd.ijstd_50_23","url":null,"abstract":"<p><strong>Context: </strong>Combating human immunodeficiency virus/acquired immunodeficiency syndrome epidemic has been possible due to advances in prevention strategies and Antiretroviral therapy (ART). Optimal adherence to ART is a major factor in achieving the desired immunological, virological, and patient well-being outcomes. Several socio-demographic, patient, treatment, and health-care system-related factors influence nonadherent behavior to ART.</p><p><strong>Aims: </strong>This study was planned to assess (1) ART adherence level, (2) factors and reasons associated with nonadherence, and (3) impact of suboptimal adherence on treatment outcomes.</p><p><strong>Settings and design: </strong>This was a cross-sectional analytical study of 300 patients in a tertiary care hospital in Puducherry, India.</p><p><strong>Methods: </strong>Random sampling was used to collect data from patient treatment cards and a predesigned structured questionnaire. The pill count method was used to calculate adherence level.</p><p><strong>Statistical analysis used: </strong>Nonadherence was chosen as a dependent variable and factors affecting adherence were chosen as independent variables. Test for significance was carried out by Chi-square test and Fisher's exact test.</p><p><strong>Results: </strong>Optimal adherence was seen in 68.3%. Factors significantly associated with nonadherence were lower education level, high prior CD4 count, irregular follow-up, missing doses in the past, and being late for pharmacy pill refills. Adherence was positively associated with mean increase in CD4 count over 6 months.</p><p><strong>Conclusions: </strong>In our study, the adherence rate is suboptimal which can lead to failure of ART. Nonadherence was associated with a decrease in CD4 count overtime. Most of the factors significantly affecting ART adherence were patient behavior related. These factors can be used for target intervention during reinforcement adherence counseling.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"19-24"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prospective observational study on species differentiation and antifungal susceptibility pattern in patients with genital candidiasis.","authors":"S Sivagamasundari, K Mahadevan, Reena Rai, Sriramajayam Lavanya","doi":"10.4103/ijstd.ijstd_58_23","DOIUrl":"10.4103/ijstd.ijstd_58_23","url":null,"abstract":"<p><strong>Background: </strong>Candidial balanitis, balanoposthitis and vulvovaginitis can be diagnosed by direct microscopy, culture and treated with antifungals. Resistance to antifungals is emerging. Hence, we conducted a study to identify the causative species and antifungal susceptibility.</p><p><strong>Aim: </strong>To observe the species differentiation and antifungal susceptibility pattern in patients with genital candidiasis.</p><p><strong>Materials and methods: </strong>A prospective observational study was carried out that included 54 patients of age group (18-60 years) diagnosed clinically and direct microscopically (KOH) for genital candidiasis. Culture was done using Sabouraud dextrose agar. Species identification and antifungal susceptibility were tested. Descriptive data were expressed in the form of frequency and percentage.</p><p><strong>Results: </strong>Out of 54 patients, 41 had culture positive candidiasis. Among the isolated species, 68.3% were <i>Candida albicans</i> (28/41) and 31.7% were non<i>- albicans Candida spp</i>. Among non-<i>albicans Candida</i> species (13/41), <i>Candida glabrata</i> (19.5%), <i>Candida tropicalis</i> (7.3%), <i>Candida guilliermondii</i> (2.4%), <i>Candida parapsilosis</i> (2.4%) were identified. Antifungal susceptibility was tested for fluconazole (FLU), clotrimazole (CLTZ), itraconazole (ITZ), ketoconazole (KTZ), voriconazole (VOR), amphotericin-B (AMPH-B). Except <i>C. glabrata</i> and <i>C.parapsilosis</i>, all other species were sensitive to all tested antifungals. All isolated species were sensitive to KTZ, VOR, AMPH-B, and CLTZ. Nearly 22% of isolates were resistant to fluconazole.</p><p><strong>Conclusion: </strong><i>C. glabrata</i> causes complicated, severe recurrent vulvovaginitis which is fluconazole resistant. Drug sensitivity prior prescribing antifungal agent identifies appropriate drug, decreases patient's disease morbidity and cross resistance.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"11-14"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical presentation of molluscum contagiosum infection in a human immunodeficiency virus-positive patient.","authors":"Agnes Ramadimetja Sema-Ramashala, Ooko Francis","doi":"10.4103/ijstd.IJSTD_104_18","DOIUrl":"10.4103/ijstd.IJSTD_104_18","url":null,"abstract":"<p><p>Molluscum contagiosum (MC) is a skin infection caused by a virus of the poxvirus family. The infection is usually innocuous and inconsequential, occasionally resolving spontaneously. It is rarely associated with such severe physical and psychological morbidity. The clinical lesions are usually painless papules or nodules with central umbilication. Painful anogenital tumors exhibiting a cerebriform surface have rarely been reported. MC infection in human immunodeficiency virus (HIV)-infected patients may present with generalized papules and papulonodules, and sometimes, progression to tumorous lesions. Early detection and effective treatment of the infection in HIV patients will go a long way in preventing progression to tumors, which are known to be resistant to treatment. The tumors responded well to X-ray external beam radiotherapy.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 1","pages":"44-46"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}