Section on Pediatric Trainees Program最新文献

{"title":"Hemolytic Uremic Syndrome Associated with Entamoeba Histolytica","authors":"Alina Bahlavouni, Aleena Paul","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.866","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.866","url":null,"abstract":"Introduction: Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized by progressive kidney injury from damage to the renal microvasculature, microangiopathic hemolytic anemia, and thrombocytopenia secondary to destruction and consumption of platelets. In most cases, HUS occurs after a severe bowel infection with certain toxic strains of the bacteria E. coli; however rarer causative organisms have also been reported, as in this patient. Case Presentation: A two-year-old male presented with three days of fever, watery diarrhea, and decreased oral intake in the setting of recent freshwater pond exposure one …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122655001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Necrotizing Pneumonia and Persistent Bacteremia in a Teenager with a History of Vaping","authors":"Nathaniel K. Breslin, Issa Hanna, Nizar F. Maraqa","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.881","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.881","url":null,"abstract":"A 15-year-old previously healthy male with a history of vaping and electronic cigarette (e-cigarette) use was hospitalized due to worsening breathing difficulty and hypoxemia. He had tested positive for influenza B a few days earlier but his condition acutely worsened despite symptomatic management. During hospitalization, he required intensive care management of acute hypoxic respiratory failure secondary to a necrotizing pneumonia with bilevel positive airway pressure (BiPAP) support and broad-spectrum …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125709029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NTRK Fusion-Positive Congenital Spinal Glioblastoma treated with Carboplatin, Etoposide, and Larotrectinib","authors":"G. Vallis","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.874","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.874","url":null,"abstract":"Introduction Primary spinal glioblastoma multiforme (GBM) is a rare central nervous system tumor accounting for less than 3% of pediatric central nervous system tumors. The congenital form of this malignancy is even more unusual. Here we present a case of a newborn diagnosed at birth with an advanced spinal cord congenital glioblastoma and successfully treated with etoposide/carboplatin chemotherapy and Larotrectinib. Case Description The patient was born full term via induced vaginal delivery due to decreased fetal movement. She was noted to have decreased tone in the delivery room, with a postured right arm; MRI of the brain and spine revealed an infiltrative mass in …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129785999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bone to Pick: A Case of Infantile Cortical Hyperostosis","authors":"L. Rosenberg, Amy M Beeson, N. Ma","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.841","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.841","url":null,"abstract":"","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131359834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Cause of Acute Onset Movement Disorder In An Adolescent: A Rare Pediatric Presentation Of Chorea-Hyperglycemia-Basal Ganglia Syndrome","authors":"J. Elkin, J. Tencer, S. Yum","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.849","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.849","url":null,"abstract":"","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115899635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Upper Gastrointestinal Hemorrhage in a Coronavirus Disease of 2019 Positive Pediatric Patient with Sickle Cell Disease","authors":"Silvia Schibeci Oraa, Tian Liang, J. Patel, Shipra Jain, N. Bhurji, S. Hassan, Reem Saadoon, Dalia Arostegui, Katherine Vaidy, R. Sinert, V. S. Shah","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.845","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.845","url":null,"abstract":"Background: SARS CoV-2, the virus that causes Coronavirus Disease of 2019 (COVID-19), most commonly presents as a febrile respiratory illness Atypical symptoms are being increasingly recognized including myalgias, anosmia, vomiting, and diarrhea Pediatric COVID-19 infections are usually mild, self-limiting, and rarely require hospitalization We describe a case of severe upper gastrointestinal bleeding as the only initial symptom of COVID-19 infection in a child with sickle cell disease (SCD) Case: A 12-year-old male with SCD, HbSS subtype, with a history of splenectomy presented to our Emergency Department (ED) with acute onset progressively worsening hematemesis for the past 24 hours He denied fever, cough, melena, peptic ulcer disease, family history of excessive bleeding, or regular nonsteroidal anti-inflammatory drug use Upon arrival, the patient had tachycardia, hypotension (HR 150, BP 86/40), and cool extremities with delayed capillary refill His temperature was 100 0F with an oxygen saturation of 100% on room air His initial laboratory results were significant for hemoglobin of 4 1 g/dL, (baseline 7-8 g/dL), reticulocytes 13 7%, venous blood gas pH of 7 17, lactate of 7 3, white blood cell count of 21 7 K/uL, and prothrombin time (PT) of 19 9 seconds / INR of 1 7 His hepatic and renal function tests were within normal limits In the ED, the patient received a normal saline bolus, two units of packed red blood cells, pantoprazole, famotidine, ondansetron, tranexamic acid, and ceftriaxone His chest X-ray was unremarkable A nasopharyngeal COVID-19 swab was sent Pediatric gastroenterology and hematology were consulted, and he was admitted to the pediatric intensive care unit The following day he underwent esophagogastroduodenoscopy which showed diffuse hemorrhagic gastropathy with superficial mucosal bleeding and without frank ulcers (Figure 1) An abdominal ultrasound revealed a normal gallbladder, no portal hypertension, and known absent spleen His nasopharyngeal swab was positive for COVID-19 Helicobacter pylori testing was sent and reported negative He received Vitamin K and two units of fresh frozen plasma for his coagulopathy resulting in normalization in his PT/INR He did not have any further hematemesis but developed melena which improved, and he was discharged with a hemoglobin of 9 3 g/dL Discussion: To date, we have not seen reports of either upper gastrointestinal bleeding as the only initial presenting symptom of COVID-19 or endoscopic visualization of gastric lumen during acute infection The petechial hemorrhaging located at the body of the greater curvature and fundus of the stomach is an unusual site and indicated the underlying coagulopathy as the cause for bleeding Our patient's mild coagulopathy is consistent with other reports of critically ill COVID-19 patients This case highlights the importance of maintaining a high index of suspicion for COVID-19 infection in an immunocompromised pediatric patient with severe bleeding or ","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126710328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Child with Pulmonary Hemorrhage and Severe Anemia: An Unusual Presentation of Celiac Disease","authors":"A. Reed, C. Karwowski","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.858","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.858","url":null,"abstract":"Introduction: Celiac disease is an autoimmune disease affecting ∼1% of the general population, in which there is an abnormal mucosal response to the gluten protein in the duodenum. Celiac disease and its manifestations completely recede when gluten is removed from the diet. It is now more common to present with atypical consequences of celiac disease than with abdominal pain and diarrhea. These consequences include, but are not limited to, neurological problems, infertility, compromised dental enamel, and pulmonary hemorrhage. Pulmonary hemorrhage in the setting of celiac disease is known as Lane …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131774221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incomplete Kawasaki Disease with Evidence of Prior COVID-19 Infection","authors":"J. Fisher, Vivian Lee","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.868-A","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.868-A","url":null,"abstract":"Introduction: Currently the United States is the most affected country worldwide with COVID-19. Initial data found the majority of pediatric cases to be mild or asymptomatic, with decreased hospitalizations compared to adults. Recently there are reports demonstrating systematic inflammatory illnesses in children with COVID-19, including toxic shock syndrome and Kawasaki Disease (KD). The following case describes a pediatric patient with incomplete KD and evidence of previous COVID-19 infection. Case: A healthy 2-year-old female presented with 5 days of fever, polymorphous rash, and conjunctivitis. She was found to have elevated CRP …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"357 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115941153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lupus-associated Angioedema Successfully Treated with C1 Esterase Inhibitor Concentrate in an Adolescent Female: A Case Report","authors":"Meng-Mei Li, Jeffrey Shirts, Kanishk Jha, K. Y. Chen, Jennifer Rammel","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.872","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.872","url":null,"abstract":"Introduction: Acquired angioedema is a rare complication of systemic lupus erythematosus (SLE). This type of angioedema is bradykinin-mediated and thought to be due to an acquired antibody against C1 esterase inhibitor (C1-INH). It can be difficult to manage and is often refractory to standard therapies. This case aims to describe the presentation of refractory angioedema as a presenting feature of SLE in a patient and her clinical course. She was treated with intravenous C1-INH and had a dramatic clinical improvement. The use of intravenous C1-INH in lupus-associated angioedema has …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117311795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Presentation of T-Cell Acute Lymphoblastic Leukemia: Syncope and Hypercalcemia of Malignancy","authors":"A. L. Mason, Victoria Mitre, S. Yusuf","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.850","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.850","url":null,"abstract":"Introduction: Hypercalcemia is an exceedingly rare presentation of T-cell acute lymphoblastic leukemia (ALL) in children. While often varied and nonspecific, the clinical manifestations of hypercalcemia can provide a clue to severe underlying disease, making prompt diagnosis imperative. Case Description: A previously healthy 14-year-old girl presented to the emergency department after multiple witnessed syncopal episodes. The events were preceded by dizziness and lasted approximately 10-15 seconds. She had no associated abnormal movements, incontinence, or subsequent confusion. Review of systems revealed one episode of emesis; left rib pain, polyuria, and polydipsia for …","PeriodicalId":446959,"journal":{"name":"Section on Pediatric Trainees Program","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121509258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}