Molecular Imaging and Radionuclide Therapy最新文献

{"title":"Isolated Diffuse Bone Marrow Metastases From Signet-ring Cell Gastric Carcinoma","authors":"T. Chow","doi":"10.4274/mirt.galenos.2023.17037","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2023.17037","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"162 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139849013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Diffuse Bone Marrow Metastases From Signet-ring Cell Gastric Carcinoma","authors":"T. Chow","doi":"10.4274/mirt.galenos.2023.17037","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2023.17037","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" 10","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/CT and 68Ga-DOTATATE PET/CT Findings of Polycystic Kidney-derived Paraganglioma","authors":"Zehranur Tosunoğlu, Sevim Baykal Koca, N. Ergül, T. Çermik, E. Arslan","doi":"10.4274/mirt.galenos.2024.03264","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.03264","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"16 2","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139850560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Performance Evaluation of Commonly Used Colormaps for Image Display in Myocardial Perfusion Imaging: Analysis based on Perceptual Metrics","authors":"Mohsen Qutbi","doi":"10.4274/mirt.galenos.2024.34711","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.34711","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"19 5","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139849455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lincoln Sign: A Rare Presentation of Medication-related Osteonecrosis of the Jaw","authors":"T. Chow, Jocelyn Chu","doi":"10.4274/mirt.galenos.2023.37980","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2023.37980","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" 10","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139788557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revision of the Histopathological Examination Following 68Ga- DOTA-FAPI-04 PET/CT of a Breast Tumor Diagnosed as Invasive Ductal Carcinomatosis","authors":"N. Alan Selçuk, Kaan Akçay, Gamze Beydağı, Ömer Sönmez, Serkan Çelik, B. Öven, L. Kabasakal","doi":"10.4274/mirt.galenos.2024.89106","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.89106","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" 7","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139790138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revision of the Histopathological Examination Following 68Ga- DOTA-FAPI-04 PET/CT of a Breast Tumor Diagnosed as Invasive Ductal Carcinomatosis","authors":"N. Alan Selçuk, Kaan Akçay, Gamze Beydağı, Ömer Sönmez, Serkan Çelik, B. Öven, L. Kabasakal","doi":"10.4274/mirt.galenos.2024.89106","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.89106","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"104 2","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139849870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celebrating the 50^th Anniversary of Nuclear Medicine in Türkiye Along with the 100^th Anniversary of Turkish Republic.","authors":"Murat Fani Bozkurt","doi":"10.4274/mirt.galenos.2023.38233","DOIUrl":"10.4274/mirt.galenos.2023.38233","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"32 3","pages":"191-194"},"PeriodicalIF":0.9,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/3d/MIRT-32-191.PMC10600549.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumonia with Intense ⁶⁸Ga-FAPI Uptake Mimicking Metastasis on ⁶⁸Ga-FAPI PET/CT in a Patient with Rectal Cancer.","authors":"Özge Erol Fenercioğlu,&nbsp;Ediz Beyhan,&nbsp;Nilay Şengül Samancı,&nbsp;Tevfik Fikret Çermik,&nbsp;Nurhan Ergül","doi":"10.4274/mirt.galenos.2023.07830","DOIUrl":"10.4274/mirt.galenos.2023.07830","url":null,"abstract":"<p><p>A 70-year-old man with newly diagnosed rectum adenocarcinoma was referred to ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) for staging, and ⁶⁸Ga-fibroblast activation protein inhibitor (FAPI)-04 PET/CT for ongoing trial. Both ¹⁸F-FDG PET/CT and ⁶⁸Ga-FAPI-04 PET/CT showed intense uptake in the primary rectal tumor, and also in nodular areas in the right lung. Due to intense ⁶⁸Ga-FAPI-04 and ¹⁸F-FDG uptake, the lung lesions were considered as metastases. However the lesions were reduced in size on CT after 20 days antibiotherapy and diagnosed as pneumonia.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"32 3","pages":"237-238"},"PeriodicalIF":0.9,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/bb/MIRT-32-237.PMC10600547.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Findings on the Use of [²²⁵Ac]Ac-DOTATATE Therapy as a Theranostic Application in Patients with Neuroendocrine Tumors.","authors":"Emre Demirci,&nbsp;Nalan Alan Selçuk,&nbsp;Gamze Beydağı,&nbsp;Meltem Ocak,&nbsp;Türkay Toklu,&nbsp;Kaan Akçay,&nbsp;Levent Kabasakal","doi":"10.4274/mirt.galenos.2023.38258","DOIUrl":"10.4274/mirt.galenos.2023.38258","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the stability, safety, and efficacy of alpha-targeted therapy with [²²⁵Ac]Ac-DOTATATE in patients with grade 1/2 metastatic neuroendocrine tumors (NETs).</p><p><strong>Methods: </strong>This retrospective cohort included patients (n=11) with metastatic NETs from different primary sites (bronchial, pancreatic, nonpancreatic gastroenteropancreatic NETs, paraganglioma, and unknown primary site) treated with [²²⁵Ac]Ac-DOTATATE with a mean activity of 8.2±0.6 MBq (range: 7.5-10.0 MBq) at our institution between November 2019 and March 2022. The <i>in vivo</i> and <i>in vitro</i> stability of [²²⁵Ac]Ac-DOTATATE was calculated. The safety profile was evaluated according to the CTCAE-v5.0. Treatment efficacy was evaluated according to [⁶⁸Ga] Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) images and the RECIST 1.1 criteria.</p><p><strong>Results: </strong>Patients had 73% (n=8) lymph node metastases, 91% (n=10) liver metastases, 36% (n=4) lung metastases, and 73% (n=8) bone metastases. All but one patient was refractory to treatment with [¹⁷⁷Lu]Lu-DOTATATE. [²²⁵Ac]Ac-DOTATATE was stable for at least 5 h in vitro (in saline) and 3 h <i>in vivo</i> (urine and blood samples). Grade 2 renal toxicity and grade 2 hematotoxicity were observed in one patient. No grade 3-4 toxicities were reported. According to post-treatment [⁶⁸Ga]Ga-DOTATATE PET/CT (n=9), 11% (n=1) had progressive disease, 44.4% (n=4) had stable disease, and 44.4% (n=4) had a partial response. The disease control rate was 89% (n=8). The median progression-free survival estimated according to Kaplan-Meier analysis was 12 months.</p><p><strong>Conclusion: </strong>The preliminary results of this study suggest that [²²⁵Ac]Ac-DOTATATE is stable, safe, and effective for treating advanced and [¹⁷⁷Lu] Lu-DOTATATE-refractory NETs. However, prospective studies are needed to determine the impact of treatment on overall survival and to uncover potential side effects.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"32 3","pages":"226-232"},"PeriodicalIF":0.9,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fe/5c/MIRT-32-226.PMC10600558.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}