{"title":"Determination of the Maximum Nonlethal Dose of Lidocaine and Epinephrine Based on Subcutaneous Injection in Rabbits","authors":"Leonardo Dalo","doi":"10.53902/mrprs.2022.02.000523","DOIUrl":"https://doi.org/10.53902/mrprs.2022.02.000523","url":null,"abstract":"Background: The objective of the present study was to determine the maximum nonlethal dose of epinephrine, lidocaine, and both substances diluted in saline subcutaneously injected in rabbits. Methods: The animals were divided into three groups. The first group received a maximum dose of subcutaneous epinephrine diluted in 30mL of saline with decreasing doses of epinephrine: 10.01mg/kg, 7.25mg/kg, 5.32mg/kg, 2.51mg/kg, 1.85mg/kg, 2.8mg/kg, and 1.21mg/kg. The second group received 30mL of saline with decreasing doses of lidocaine 250, 200, 150, 125, 100, 75, and 50mg/kg, respectively. The animals were observed from 48 hours to 7 days after receiving the injection. The third group also received 30mL of saline containing a fixed dose of 0.03mg of epinephrine and the same decreasing doses of lidocaine as the second group. After receiving the injection, the animals were observed for 48 hours for adverse reactions, death, and absence of vital signs. Results: In the first group, the dose of 1.21mg/kg of epinephrine has proved to be nonlethal. In the second group, a dose of 50mg/kg of lidocaine subcutaneously injected to rabbits caused neither visible reactions nor death. Finally, in the third group, lidocaine plus epinephrine at a dose of 75mg/kg plus 0.03mg in the saline did not cause visible reactions or death. Conclusion: Lidocaine injected into the subcutaneous tissue of rabbits at a dose of 50mg/kg did not cause visible reactions or death.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122093281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Modification in Transabdominal Approach for Breast Augmentation (TABA) in Combined Surgery Patients","authors":"Güçer T","doi":"10.53902/mrprs.2023.03.000527","DOIUrl":"https://doi.org/10.53902/mrprs.2023.03.000527","url":null,"abstract":"In combined surgery candidates, the transabdominal way to locate breast implants are preferred and applied with the abdominoplasty, aspiration lipoplasty and breast augmentation together in indicated cases. In 46 cases, very rare complication rate is observed as 3 cases with seroma in upper epigastric area and no infection or tissue circulation or nervous (sensorial) problems are observed. The technique contains a lower plane abdominoplasty incision, the wet technique saline infiltration to the abdominal area, aspiration lipoplasty following excess skin of the belly and undermining the central line, reaching medial breast regions, and fish hook shaped dissections from the medial supra fascial pectoral areas for the estimated volume of the breast implants differently from the previously described technique. Following the application of the implants, the skin between the breasts over the sternum, reattached to the base of the prepared hole with a fixation suture to facilitate the tunnel obliteration, and plication of rectus fascia and closing the incision of abdominoplasty completes the operation. A drainage provided by flat (7 or 10 mm Jackson-Pratt) drains applied for 48 hours following surgery. External combined garment for abdominoplasty and breast augmentation is applied for six weeks. By this vertical midline single tunneling technique, the previously described TABA surgery can be performed in a shorter operation time and lesser deformity and complication rate. EBM is accepted as Level V, Opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126644215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Double-Advance Technique for the Closure of Inferior Cleft Lip","authors":"G. D.","doi":"10.53902/mrprs.2022.02.000520","DOIUrl":"https://doi.org/10.53902/mrprs.2022.02.000520","url":null,"abstract":"The Objective is present a case of a medial cleft of the lower lip with associated ankyloglossia and a proposal for a double-advance local flap technique for its closure who attended the Oral and Maxillofacial Surgery Service of the Madre Rafols Hospital, Venezuela. A 4-month-old female patient, presenting a medial cleft of the lower lip with an associated aberrant frenulum of the tongue causing ankyloglossia (Tessier 30). Lingual frenectomy and primary cheiloplasty were performed with a double-advance local flap technique to close the lower labial cleft. A wedge-shaped incision along the labial cleft, with lateral extensions towards the mentolabial sulcus extending bilaterally were performed in order to advance both flaps and place the wound at the limit of the esthetic subunit, as well as a Z-plasty in the vermilion of the lower lip. Postoperative follow-ups did not reveal local complications or tissue dehiscence. Due to the rarity of this entity, relevant surgical techniques for this type of anomaly have not been established or evaluated. The technique presented here proved its usefulness, achieving harmonious and favorable functional and aesthetic results in our patient.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122747960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aesthetic Otoplasty, Reduction of Shell, Neo-antihelixplasty, Ear Shell Mastoid Reangulation Procedures","authors":"P. V","doi":"10.53902/mrprs.2021.01.000508","DOIUrl":"https://doi.org/10.53902/mrprs.2021.01.000508","url":null,"abstract":"This study aims to demonstrate the technical approach for the correction of antihelix flattening (Kaye’s Method), for shell reduction by wedge resection and for skull reangulation.(Frank Welsh).","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125948225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overgrowth Syndrome and Multi-Stage Reconstruction of Hand and Feet Deformations","authors":"E. Vrabič","doi":"10.53902/mrprs.2020.01.000501","DOIUrl":"https://doi.org/10.53902/mrprs.2020.01.000501","url":null,"abstract":"A case of asymmetric overgrowth of feet, fingers and toes is presented and the performed diagnostic and multi-stage surgical reconstruction described. The condition in hands and feet was already present at birth. The hypertrophic growth advanced progressively, and histological investigation of the affected tissues revealed no pathology. The examination of inner organs, skin, subcutaneous tissue, nerves and vessels showed no deviations, the girl's karyotype was normal, 46 xx, no mosaicism was confirmed. In view of the new diagnostic criteria, this case cannot be assigned to any of the overgrowth syndromes. The most suitable classification would be in the group of Proteus-like syndrome. At this time only isolated hypertrophy of soft tissues and skeleton is present. According to the data from the literature, later development of anomalies is possible, so Proteus-like syndrome cannot be completely excluded.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126354910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Necrotizing Cellulitis Post Thighs Liposuction","authors":"A. de","doi":"10.53902/mrprs.2021.01.000513","DOIUrl":"https://doi.org/10.53902/mrprs.2021.01.000513","url":null,"abstract":"A serious complication post liposuction is presented. The patient with a necrotizing cellulitis of a thigh and a nerve injury due to the debridement done before she was referred to our hospital. She needed multiple surgical and intensive care procedures to save her life. Two years after the incident, the residual defect was repaired with multiple consecutive expansions.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132258525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT Angiography in the Preoperative Evaluation as a Predictor of Surgical Time for DIEP","authors":"Moraes Pithon Napoli JV","doi":"10.53902/mrprs.2021.01.000506","DOIUrl":"https://doi.org/10.53902/mrprs.2021.01.000506","url":null,"abstract":"Computed tomography angiography (CT-angiography) provides a clear view of the perforating vessels and their course, being essential in the preoperative evaluation of mastectomies. In the case of DIEP (deep lower epigastric artery), the prior identification of these vessels is of great importance for breast reconstruction, because in addition to being a predictor of surgical time, it helps in the correct approach of the arteries. Objective: To analyze CT angiography as a predictor of the surgical time for DIEP, when performed in the preoperative evaluation. Methods: A database from the Royal Perth Hospital in Australia was analyzed, with a total of 104 mastectomies performed during the period from January to December 2017. Among them, 19 were for breast reconstruction by DIEP. The patients had an average of 47 years, ranging from 31 to 69 years. Results: We obtained that when the average number of arteries in the CT angiography is less than four, there will be an average decrease of 34 minutes in the total time of surgery. However, if the number is greater than or equal to five arteries, there will be an average increase of 34 minutes, totaling an average of 452 and 551 total minutes of surgery, respectively. Conclusion: Angio-CT is an important predictor to predict the average time of surgery, one of the main factors related to complications when prolonged.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132126644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment Strategies and Outcomes of Medication Related Osteonecrosis of the Jaw (MRONJ)","authors":"Goldfield Eb","doi":"10.53902/mrprs.2021.01.000510","DOIUrl":"https://doi.org/10.53902/mrprs.2021.01.000510","url":null,"abstract":"Medication Reliated Osteonecrosis of The Jaws (MRONJ); Caused by maxillofacial surgical procedures performed during or after antiresorptive, antiangiogenic and bisphosphonate treatments; It is a newly defined disease and its etiopathogenesis is still not fully understood. Studies on the definition, staging and treatment approaches of the disease are evaluated by the commission formed by the American Association of Maxillofacial Surgeons, and guidelines expressing opinions on these issues are published; Discussions still continue on the treatment approaches of the disease. Conservative, surgical, alternative and their combinations methods are used in the treatment of the disease, depending on the level of bone and soft tissues affected.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130957009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pubic to Scalp F.U.E. Hair Transplant for Transgender","authors":"V. V","doi":"10.53902/mrprs.2021.01.000512","DOIUrl":"https://doi.org/10.53902/mrprs.2021.01.000512","url":null,"abstract":"A male to female Transgender. She has bitemporal receding from androgenic alopecia, which is not very desirable. She seeks some kind of camouflage, after female hormone, Minoxidil and Finasteride particular hairstyle, hairpieces, etc. Her last resource is Hair Transplant to cure her baldness. FUE from the occipital scalp (927FU) and pubic (405FU) area then transplant to the bald spot is the final solution. 1,332FU was done. Hairline construction follows the “Line Thai Micro Hairline principle.” Nine months later, she comes back with a very soft, smooth heart shape feminine hairline.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133545846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Level of Hetero Perception of the “T” Graft for the Management of Punta Nasal in a Group of Mexican Patients","authors":"Mónica Mariana Paz Alonso","doi":"10.53902/mrprs.2022.02.000524","DOIUrl":"https://doi.org/10.53902/mrprs.2022.02.000524","url":null,"abstract":"Material and Method: Retrospective descriptive study of the records of patients operated on for rhinoplasty with T-graft placement. Seven independent specialists of recognized prestige in Nasal Surgery were asked to analyze the pre-surgical and post- surgical photographs at 20 weeks, and to carry out the evaluation. From each case, granting a score, the one that evaluated with the highest qualification and the one that evaluated with the lowest qualifications were eliminated. Objective: To determine the efficacy of the \"T\" graft for the management of the nasal tip in mestizo patients. Results: 22 cases were included in the analysis, 19 women and 3 men aged between 16 and 64 years. Only one case involved secondary surgery. Improvement was observed in the projection, rotation and definition of the tip in all cases, also observing improvement in the following: the wing-columnella ratio in 86.4%, symmetry in 92.7%, obtaining a natural appearance in 92.7%, the double columnar break in 86.3% and the obtaining of luminous points in 99%. No patient had significant tip asymmetry after the surgical procedure; No patient had postoperative complications or postoperative aesthetic or functional discomfort. Conclusions: The \"T\" graft can be used successfully in cases where it is necessary to increase the projection, definition and rotation of the nasal tip that cannot be achieved only by sutures or other types of grafts, it is especially useful in cases of skin thick, and being above the domes, favors a natural aesthetic result. In addition, it is a useful graft in cases of asymmetry of alar cartilages and for correction in some cases of the wing-columnella relationship.","PeriodicalId":445602,"journal":{"name":"Modern Research in Plastic and Reconstructive Surgery","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115766540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}