{"title":"Полиномиальная аппроксимируемость асимметричной задачи о покрытии графа ограниченным числом циклов","authors":"М. Ю. Хачай, Е. Д. Незнахина, К. В. Рыженко","doi":"10.21538/0134-4889-2023-29-3-261-273","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-261-273","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49539315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Задача быстродействия обхода нескольких точек машиной Дубинса","authors":"А. М. Майер, А. А. Галяев","doi":"10.21538/0134-4889-2023-29-3-42-61","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-42-61","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46029152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Барьеры и симметричная регуляризация функции Лагранжа при анализе несобственных задач линейного программирования","authors":"Леонид Дмитриевич Попов","doi":"10.21538/0134-4889-2023-29-3-138-155","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-138-155","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46396349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Power Degrees in Dynamic Multi-Agent Systems","authors":"Leon Petrosyan, David Yeung, Y. Pankratova","doi":"10.21538/0134-4889-2023-29-3-128-137","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-128-137","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49381944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Замкнутые отображения и построение моделей расширения","authors":"Александр Георгиевич Ченцов","doi":"10.21538/0134-4889-2023-29-3-274-295","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-274-295","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44016645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Бикомпозиция конусных проекций","authors":"Е. А. Нурминский","doi":"10.21538/0134-4889-2023-29-3-73-87","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-73-87","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42528312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
С. С. Аблаев, Федор Сергеевич Стонякин, М. С. Алкуса, Александр Владимирович Гасников
{"title":"Адаптивные субградиентные методы для задач математического программирования с квазивыпуклыми функциями","authors":"С. С. Аблаев, Федор Сергеевич Стонякин, М. С. Алкуса, Александр Владимирович Гасников","doi":"10.21538/0134-4889-2023-29-3-7-25","DOIUrl":"https://doi.org/10.21538/0134-4889-2023-29-3-7-25","url":null,"abstract":"","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45646351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Sebastiani, C. D’Alterio, Cristina Vocca, L. Gallelli, F. Palumbo, Tommaso Cai, A. Palmieri
{"title":"Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione, and Escin on Human Health: A Narrative Review","authors":"Francesco Sebastiani, C. D’Alterio, Cristina Vocca, L. Gallelli, F. Palumbo, Tommaso Cai, A. Palmieri","doi":"10.3390/uro3030022","DOIUrl":"https://doi.org/10.3390/uro3030022","url":null,"abstract":"Background: Recently, the role of nutraceutical compounds in the prevention of human diseases has been rapidly increasing. Here, we aim to evaluate the beneficial effect of dietary supplementation with seven active principles, i.e., lycopene, sulforaphane, silymarin, glutathione, escin, tryptophan, and green tea catechins, on human health. Methods: An extensive search of PubMed and Medline database was performed with the following keywords: “silymarin”, “sulforaphane”, “lycopene”, “green tea catechins”, “tryptophan”, “glutathione” and “escin” accompanied by the keywords “supplement”, “supplementation”, and “nutraceutics”. All preclinical and clinical trials were considered for this review. Results: One hundred and eighteen full-text articles were eligible for inclusion in this review. The papers examined presented considerable variability due to the wide heterogeneity of dosages administered, population involved, and outcomes pursued. Conclusion: Nutritional supplementation with lycopene, sulforaphane, silymarin, glutathione, escin, tryptophan, and green tea catechins appears to exert a wide range of benefits on human health, ranging from mood and cognition to cardiovascular health, fertility, metabolism, antioxidant, and anti-inflammatory capabilities, as well as potential anticancer effects. Further studies are required to better define the potential synergic effect, optimal dosage, mechanism of action, and tolerability profiles of these substances.","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88157639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Lambertini, Alessandro Sandulli, Vincenzo Salamone, M. Bacchiani, S. Giudici, Eleana Massaro, A. Cadenar, R. Mariottini, Simone Coco, Laia Bardina, Elena Ciaralli, Marco Saladino, A. Romano, F. Valastro, A. Grosso, F. di Maida, G. Siena, S. Scelzi, A. Mari
{"title":"Efficacy and Safety of a Natural Supplement Containing Serenoa Repens, Solanum Lycopersicum, Lycopene, and Bromelain in Reducing Symptoms of Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Cohort Study in 250 Patients","authors":"L. Lambertini, Alessandro Sandulli, Vincenzo Salamone, M. Bacchiani, S. Giudici, Eleana Massaro, A. Cadenar, R. Mariottini, Simone Coco, Laia Bardina, Elena Ciaralli, Marco Saladino, A. Romano, F. Valastro, A. Grosso, F. di Maida, G. Siena, S. Scelzi, A. Mari","doi":"10.3390/uro3030021","DOIUrl":"https://doi.org/10.3390/uro3030021","url":null,"abstract":"Background: Chronic Prostatitis/Chronic Pelvic Pain syndrome NIH-class III is a widespread condition affecting men universally, with existing treatments showing limited success. This study evaluated the efficacy and safety of a natural supplement, composed of Serenoa repens, Solanum lycopersicum, lycopene, and bromelain, in managing symptoms of this condition among a substantial patient group. Methods: In this prospective study, 245 patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain syndrome NIH-class III were treated with the aforementioned supplement, alongside lifestyle alterations, such as refraining from spicy foods, alcohol, caffeine, and cycling, for a duration of three months. Patients’ progress was assessed at one and three months using the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), the International Prostate Symptom Index (IPSS), quality of life (QoL) scores, and changes in total prostate-specific antigen (PSA) levels. Results: The supplement was well received with no serious adverse events reported. Significant improvements were observed in NIH-CPSI scores, IPSS, QoL scores, and a substantial decrease in total PSA levels at three months compared to baseline, with a positive trend noted from one-month to three-month evaluations. This was consistent in either patients with predominantly voiding or storage urinary symptoms. Conclusions: Our results suggest that this natural supplement in conjunction with lifestyle changes could offer a safe and effective alternative treatment for patients suffering from Chronic Prostatitis/Chronic Pelvic Pain syndrome NIH-class III. However, these findings require validation through further large-scale randomized controlled trials.","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84893418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Deceased Transplant Recipients: A Forgotten Source of Organ Donors","authors":"D. Nghiem","doi":"10.3390/uro3030020","DOIUrl":"https://doi.org/10.3390/uro3030020","url":null,"abstract":"Background: Organ transplantation is the most successful therapy for end-stage organ disease since it increases the quality of life and life expectancy. For these reasons, over 107,000 patients were on the waitlist in the United States for a transplant in 2022. Unfortunately, only 42,887 transplants were performed, and annually, over 7000 patients on the kidney list die or are too sick to transplant. To solve this severe organ shortage, the use of the deceased transplant recipients with functioning organs, whether transplanted or native, is explored as a new source of organ donors. Methods: To assess the feasibility of this option, first, we will review the rate of kidney transplant recipients dying with functioning grafts (DWGF), their re-use, the organ allocation system, the technical aspects of the organ procurement, and the transplantation of the DWGF kidneys. Then, we will consider the larger group of all deceased transplant recipients as potential donors for all functioning, native, or transplanted organs. Conclusions: (1). All functioning kidney transplants explanted from the deceased transplant recipients have excellent long-term function after re-transplantation. (2). The other functioning organs constitute a large unrecognized pool of transplantable organs. (3). The intensivists and the transplant community should be educated about these new options to improve the organ shortage.","PeriodicalId":44555,"journal":{"name":"Trudy Instituta Matematiki i Mekhaniki UrO RAN","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81445385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}