前列腺癌患者放射治疗引起的勃起功能障碍的现状:一个叙述性的回顾

IF 0.4 Q4 MATHEMATICS, APPLIED

Trudy Instituta Matematiki i Mekhaniki UrO RAN Pub Date : 2023-04-01 DOI:10.3390/uro3020013

Connie Labate, A. Panunzio, Francesco De Carlo, F. Zacheo, Sara De Matteis, M. Barba, U. Carbonara, F. Rizzo, S. Leo, S. Forte, P. Ditonno, A. Tafuri, V. Pagliarulo

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引用次数: 0

摘要

前列腺癌是美国男性中最常见的癌症。在不同的可用治疗方案中，建议对局部甚至晚期疾病进行放射治疗。放射治疗后，由于神经、血管和内分泌机制导致动脉张力改变，阴部神经失用，最后发生纤维化，常发生勃起功能障碍。考虑到生活质量对患者治疗选择的影响，放射治疗性ED的预防和治疗是主要问题。在这篇叙述性的综述中，我们从病理生理学和可用的治疗方案方面简要地总结和讨论了前列腺癌患者放射治疗诱导ED的现状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Current Knowledge on Radiation-Therapy-Induced Erectile Dysfunction in Prostate-Cancer Patients: A Narrative Review

Prostate cancer is the most frequently diagnosed cancer in men in the United States. Among the different available treatment options, radiation therapy is recommended for localized or even advanced disease. Erectile dysfunction (ED) often occurs after radiation therapy due to neurological, vascular, and endocrine mechanisms resulting in arterial tone alteration, pudendal-nerve neuropraxia, and lastly fibrosis. Considering the influence of quality of life on patients’ treatment choice, radiation-therapy-induced ED prevention and treatment are major issues. In this narrative review, we briefly summarize and discuss the current state of the art on radiation-therapy-induced ED in PCa patients in terms of pathophysiology and available treatment options.

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来源期刊

Trudy Instituta Matematiki i Mekhaniki UrO RAN MATHEMATICS, APPLIED-

CiteScore

0.80

自引率

20.00%

发文量