Transfusion Medicine (Oxford, England)最新文献

{"title":"Transfusion transmitted infections in thalassaemics: need for reappraisal of blood screening strategy in India.","authors":"V Shyamala","doi":"10.1111/tme.12110","DOIUrl":"https://doi.org/10.1111/tme.12110","url":null,"abstract":"<p><p>The aim of the study was to assess the blood safety in India through prevalence in thalassaemic population. Safety of the blood supply is a subject of great concern for all recipients. This review attempts to assess the relevance and format of tests for viruses in the context of transfusion transmitted infection (TTI) prevalence in India. Serological marker testing for human immunodeficiency virus-1/2 (HIV-1/2), hepatitis C virus (HCV) and hepatitis B virus (HBV) is mandatory in India. Numerous TTI incidents in the repeat recipients supported by results from nucleic acid technology (NAT) testing indicate the deficiencies in blood safety. The β-thalassaemic population (3-17%) in India has been used to reflect on blood safety. The prevalence of HIV-1/2, HCV and HBV in the Indian donor population, the limitations in accessing safe donors, quality of serological tests and the impact on repeat recipients is evaluated. The reports point to prevalence of ˜2% of viral diseases in the blood donor population, and the insufficiency of serology testing resulting in up to 45% TTIs in thalassaemics. The revelation by individual donation (ID) NAT testing, of 1 per 310 units being serology negative-NAT reactive is alarming. Extrapolating the serology negative NAT reactive yields, for an annual blood supply of 7.9 million units, 23,700 units or nearly 100,000 blood components are likely to be infectious. Though the cost for ID-NAT testing is considered unaffordable for a medium development country such as India, the enormity of TTIs will place an unmanageable cost burden on the society.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"79-88"},"PeriodicalIF":1.5,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40292646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a blood group genotyping platform (BLOODchip(®) Reference) in Japanese samples.","authors":"M Tanaka,&nbsp;I Kamada,&nbsp;J Takahashi,&nbsp;F Hirayama,&nbsp;Y Tani","doi":"10.1111/tme.12085","DOIUrl":"https://doi.org/10.1111/tme.12085","url":null,"abstract":"<p><strong>Background: </strong>Blood-group genotyping arrays have been widely used in Caucasian and African American populations, but have not been thoroughly tested in Japanese subjects.</p><p><strong>Aim: </strong>To evaluate, using the BLOODchip(®) Reference genotyping system, the concordance of previously typed samples with expected phenotypes and the coverage of the Japanese variants.</p><p><strong>Methods: </strong>Blood samples from 100 Japanese donors were obtained. DNA was extracted with QIAsymphony (Qiagen, Hilden, Germany). Samples were typed by serological methods and processed with the BLOODchip(®) . When a non-concordant result was identified, further sequencing by polymerase chain reaction-single specific primer (PCR-SSP) was performed.</p><p><strong>Results: </strong>Concordance between systems was 98% (736/751), and 98.8% (742/751) if only non-software-related non-concordances were considered. In the ABO group, 6 'No Call' (NC, inability of the BLOODchip(®) to assign a result) were ascribed to a variant of blood subtype A1 (A102; 467C>T), a common subtype in Asian populations, whereas three NC presented additional polymorphisms not contained in the BLOODchip(®) (A102/A205, A102/O06 and A204/O02). In the RhD group, one discrepancy was correctly genotyped as RHD*1227A (Del phenotype) by the BLOODchip(®) (phenotyped as partial D, RHD*DIVb). Another was phenotyped as D+ by the BLOODchip(®) (phenotyped weak D by serology) and confirmed as RHD*D-CE(2)-D heterozygous by sequencing. The 3 RhD NC can be solved by further software update. For RhCE, one discrepancy was correctly genotyped for both systems; however, only the BLOODchip(®) was able to detect RHCE*CX allele.</p><p><strong>Conclusions: </strong>By programming the A102 ABO variant into the system software with the new allele combinations, the BLOODchip(®) Reference is a suitable genotyping tool to be applied to Asian samples.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"39-44"},"PeriodicalIF":1.5,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40259744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional-motivational barriers to blood donation among Togolese adults: a structural approach.","authors":"K Alinon,&nbsp;K Gbati,&nbsp;P C Sorum,&nbsp;E Mullet","doi":"10.1111/tme.12082","DOIUrl":"https://doi.org/10.1111/tme.12082","url":null,"abstract":"<p><strong>Background: </strong>Although the number of blood donors has been rapidly increasing in Togo since 2003, it is nevertheless insufficient to cover the demand.</p><p><strong>Objectives: </strong>To increase needed blood donation in Togo, it is necessary to understand why most people are reluctant to do it.</p><p><strong>Methods: </strong>A sample of 400 adult volunteers in Lomé, mostly university educated, rated, on a scale of 0-10, the relevance to them of a comprehensive list of reasons that might deter people from donating blood. The ratings of 250 participants were subjected to factor analysis, and the resulting factorial structure was confirmed on the ratings of the other 150 participants.</p><p><strong>Results: </strong>The resulting six factors were labelled (in order of their ratings of a representative sample of items): Lack of Courage and Lack of Information (mean 5·43 of 10), Concerns about the Use of Blood (4·72), Risk Aversion (4·37), Fear of Medical Settings (2·41), Conformity with Tradition (1·88) and Indifference to Others and Hostility to the Procedure (1·69).</p><p><strong>Conclusion: </strong>To increase blood donation, a public information campaign should address the emotional-motivational barriers found even in the most educated segment of Togolese society.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"21-6"},"PeriodicalIF":1.5,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12082","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40259916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Deferasirox for the treatment of iron overload in Chinese thalassaemia major patients: results from a prospective, open-label, multicentre clinical trial.","authors":"Y-R Lai,&nbsp;R-R Liu,&nbsp;C-F Li,&nbsp;S-L Huang,&nbsp;Q Li,&nbsp;D Habr,&nbsp;N Martin,&nbsp;Z-X Shen","doi":"10.1111/tme.12077","DOIUrl":"https://doi.org/10.1111/tme.12077","url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy and safety of deferasirox in Chinese thalassaemia major (TM) patients</p><p><strong>Background: </strong>EPIC (Evaluation of Patients' Iron Chelation with Exjade(®)) was a large multi-national study and, notably, the first clinical trial of an iron chelator registered with the Chinese State Food and Drug Administration.</p><p><strong>Methods: </strong>Efficacy and safety of deferasirox were compared in Chinese (n = 117) and non-Chinese (n = 998) TM patients. Deferasirox was initiated at 20 mg kg(-1)  day(-1), with titration increments of 5-10 mg kg(-1) day(-1), based on serum ferritin trends and safety parameters.</p><p><strong>Results: </strong>At baseline, Chinese patients were younger than non-Chinese (mean age 6·8 versus 19·5 years), with higher median serum ferritin (4519 vs 3058 ng mL(-1)). Over 1 year, mean actual deferasirox dose was similar for Chinese and non-Chinese patients (24·6 and 24·0 mg kg(-1)  day(-1), respectively); median serum ferritin did not change significantly from baseline in Chinese patients (+340 ng mL(-1), P = 0·102) and significantly decreased in non-Chinese patients (-220 ng mL(-1); P < 0·001). In the 1-year extension in Chinese patients, (mean actual deferasirox dose 33·6 mg kg(-1)  day(-1)), median serum ferritin decreased (-756 ng mL(-1); P = 0·0397), with a numerically higher reduction in patients aged ≥6 to  < 12 than <6 years (-982 vs -457 ng mL(-1), respectively). The safety profile of deferasirox in Chinese patients was similar to the overall population with respect to clinically-relevant findings.</p><p><strong>Conclusion: </strong>Age and deferasirox exposure influenced study findings, supporting the need for longer-term treatment and dose escalation to ≥30 mg kg(-1)  day(-1) to achieve neutral or negative iron balance in heavily iron overloaded and younger Chinese patients.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"389-96"},"PeriodicalIF":1.5,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40256941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ALT cut-off value for blood donor screening should be established for servicemen separately.","authors":"X Deng,&nbsp;D Wang","doi":"10.1111/tme.12035","DOIUrl":"https://doi.org/10.1111/tme.12035","url":null,"abstract":"Dear Sir, Recently, the Chinese new standard GB 18467-2011 Health examination criteria of blood donors was put in practice from 1 July 2012. This new version made some amendments, such as the health consulting, donation intervals and volume. For the plasma alanine transaminase (ALT) screening test, requirements changed from <40 IU L−1 to ‘Meets related requirements’. There are still some controversies about whether it is suitable or even necessary for donor blood ALT screening since the 1980s (Silverstein et al., 1984; Khedmat et al., 2007). Owing to the low specificity of ALT activity and the application of nucleic acid test (NAT), the ALT screening of blood donors seems valueless. But in China and some European countries, it is recommended or even required by law (Brinkmann et al., 2003). Usually, the upper limit of ALT activity for blood donors are determined according to the upper limit of the reference intervals for normal person (from 1·5 to 3·0 times) (Brinkmann et al., 2003). In our department, for the old version of GB 18467-2001 required ALT < 40 IU L−1, just fit the upper limit of the reference interval which we used to make it as the cut-off value for blood donor screening. As military hospital was operated and serviced by the PLA army, our department was authorised to collect whole blood from servicemen. In the past few years, we examined the plasma ALT activity of both servicemen and local donors. Results showed that from 2005 to 2007, the discard rate for simply elevated ALT activity of service and local donors were 7·24% (1553/21453) and 3·51% (504/14351), respectively (χ2 = 220·588, P = 0·000). The elevated ALT activity of serviceman may be due to their strenuous physical exertion. The reference interval of plasma ALT activity of the army men needs to be established separately. In 2008, 1720 servicemen were involved in the investigation about plasma ALT activity after obtaining their informed consent. Three millitres of venous blood was collected using lithium heparinate; plasma was separated and analysed within 4 h of blood draw by ADVIA2400 (Semens, Germany). Reference interval was established according to standard Clinical and Laboratory Standards Institute (CLSI) CA28-2 and the work done by Chan et al. (2008). All data were processed by spss 11.0 using non-parametric program for descriptive. The distribution of plasma ALT activity (Fig. 1) does not follow-up the normal","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"281-2"},"PeriodicalIF":1.5,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40226155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variation of motivation between weekday and weekend donors and their association with distance from blood donation centres.","authors":"C M Poon,&nbsp;S S Lee,&nbsp;C K Lee","doi":"10.1111/tme.12034","DOIUrl":"https://doi.org/10.1111/tme.12034","url":null,"abstract":"<p><strong>Background: </strong>Maintenance of an effective pool of regular donors is important for protecting public health. In planning the development of blood donation services, motivation for repeat donation would need to be considered in context of the location of blood donation centres in the community.</p><p><strong>Study design and methods: </strong>Donors giving blood in January 2012 were invited to participate in a cross-sectional study by completing an anonymous online questionnaire. Residence and work/school locations were collected together with demographics and donation histories. Motivated donors were compared with less motivated ones in terms of their timing of blood donation and the spatial relationship with the donor centres.</p><p><strong>Results: </strong>A total of 3744 questionnaires were completed, representing a response rate of 16.4%. Weekday centre donors were less likely to have returned for blood donation within a year [odds ratio (OR) = 0.79, 95% confidence interval (CI) = 0.65-0.96] and intend to donate in the following 6 months (OR = 0.69, 95% CI = 0.49-0.97). Living further away from the donor centres gave a higher OR for giving blood during weekdays among motivated centre donors, but such association was absent among less motivated centre donors. Regardless of the level of donors' motivation for blood donation, fewer weekday donations were made if the distance between location of school or workplace and donor centre increased.</p><p><strong>Conclusion: </strong>Blood donation behaviour was associated with both the accessibility of donor centres and daily commuting patterns of the residents. Motivated centre donors were making more donations, regardless of the distance.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"152-9"},"PeriodicalIF":1.5,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40225986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intention of future donations: a study of donors versus non-donors.","authors":"J D Martín-Santana,&nbsp;A Beerli-Palacio","doi":"10.1111/tme.12005","DOIUrl":"https://doi.org/10.1111/tme.12005","url":null,"abstract":"<p><strong>Background: </strong>Recent years have seen the level of blood donation at a world level come to a standstill or even decline. This situation requires blood donation services to make efforts to increase donor recruitment and retention, as well as to increase the frequency of donations among current donors. In order to obtain good results, it is essential to understand the factors that affect intention to donate.</p><p><strong>Objectives: </strong>To determine the explanatory power of a set of factors on intention to donate blood, as well as evaluating the ability of current donors to motivate others.</p><p><strong>Methods/materials: </strong>A questionnaire was administered to a sample of 1015 Spanish individuals.</p><p><strong>Results: </strong>Results indicate that (i) motivations and hindering factors have the greatest explanatory power on intention to donate, (ii) experience as a donor is the most explanatory factor on future intention and (iii) there are significant behavioural and sociodemographic differences between donors and non-donors.</p><p><strong>Conclusion: </strong>These findings suggest that it is necessary (i) to enhance the donor retention for maintaining the donation system using a personal and frequent communication with donors not only to remind them to schedule their next donation, but also to attract more donors; (ii) to recapture temporarily deferred donors, as they are less reluctant towards donation; (iii) to describe in detail how donation affects donors and clarify the importance of donation for society and (iv) to develop member get member programs in which current donors act as motivators amongst friends, coworkers and family.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"77-86"},"PeriodicalIF":1.5,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/tme.12005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40203271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful treatment of pure red cell aplasia with a single low dose of rituximab in two patients after major ABO incompatible peripheral blood allogeneic stem cell transplantation.","authors":"W Zhidong,&nbsp;Y Hongmin,&nbsp;W Hengxiang","doi":"10.1111/j.1365-3148.2012.01156.x","DOIUrl":"https://doi.org/10.1111/j.1365-3148.2012.01156.x","url":null,"abstract":"Dear Sir, Pure red cell aplasia (PRCA) occurs in 10–20% patients who underwent ABO-incompatible allogeneic haematopoietic stem cell transplantation (allo-HSCT). The mechanism for PRCA has been presumed to be persistence of recipient isohaemagglutinins, produced by residual host B lymphocytes or plasma cells, which are directed against donor erythroid progenitors (Sahovic et al., 1991). However, optimal treatment of PRCA after HSCT is not well established. Rituximab is a chimeric IgG1 monoclonal antibody directed against the CD20 surface antigen expressed by most human B lymphocytes and may eradicate B cells in vivo (Carton et al., 2004). Here, we report two patients with PRCA after ABO incompatible allogeneic peripheral blood stem cell transplantation (PBSCT) successfully treated with a single low dose of rituximab.","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"302-4"},"PeriodicalIF":1.5,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-3148.2012.01156.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40189078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The current need for family and replacement donation in sub-Saharan Africa should not hide the difficulties of its management.","authors":"C T Tagny","doi":"10.1111/j.1365-3148.2012.01157.x","DOIUrl":"https://doi.org/10.1111/j.1365-3148.2012.01157.x","url":null,"abstract":"Dear Sir, Family replacement donation was initially described as a type of donation which is more risky than the voluntary not remunerated (VNR) donation and even during the last decade (Cunha et al., 2007; Mbanya & Tayou, 2005). For many years, this has consolidated WHO in the promotion of VNR donation (WHO, 2001, 2004). Currently, the majority of the countries having chosen exclusively the strategy of supply from VNR donation still do not have sufficient blood supply, in spite of the considerable assistance of international partners (Tagny et al., 2011). Family replacement donation still constitutes for several countries, an essential source of blood, notably when VNR blood donors are not available during school or university holidays. Blood supply from family replacement donation reduces the significant needs caused particularly by infectious diseases, anaemia from traumatic or obstetrical origins. Moreover, the cost of the exclusive supply from VNR donation remains hard to bear by the limited budget of the countries which adopted it. Indeed, the cost of a blood bag from a VNR donation is two to four times higher than that of a unit from a family replacement donation because of a high cost of the activities of promotion, mobile collection and quality system (Allain, 2011; Bates et al., 2007). Recently, some studies also asserted a weighty argument in favour of the family replacement donation: contrary to preceding information, it would be as much at risk as the VNR donation in first time donors (Allain, 2011). Only regular donation, family replacement as well as voluntary non-remunerated, are more capable to provide a supply at low risk. The combined use of the two types of donation is necessary but must gradually leave the place to a pool of regular donors capable to provide sustainable supply at lower risk. So, currently the family replacement donation remains useful; however, its daily management is problematic.","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"298-9"},"PeriodicalIF":1.5,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-3148.2012.01157.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40188941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient involvement in blood transfusion safety: patients' and healthcare professionals' perspective.","authors":"R Davis,&nbsp;M F Murphy,&nbsp;A Sud,&nbsp;S Noel,&nbsp;R Moss,&nbsp;M Asgheddi,&nbsp;I Abdur-Rahman,&nbsp;C Vincent","doi":"10.1111/j.1365-3148.2012.01149.x","DOIUrl":"https://doi.org/10.1111/j.1365-3148.2012.01149.x","url":null,"abstract":"<p><strong>Background: </strong>Blood transfusion is one of the major areas where serious clinical consequences, even death, related to patient misidentification can occur. In the UK, healthcare professional compliance with pre-transfusion checking procedures which help to prevent misidentification errors is poor. Involving patients at a number of stages in the transfusion pathway could help prevent the occurrence of these incidents.</p><p><strong>Objectives: </strong>To investigate patients' willingness to be involved and healthcare professionals' willingness to support patient involvement in pre-transfusion checking behaviours.</p><p><strong>Measures: </strong>A cross-sectional design was employed assessing willingness to participate in pre-transfusion checking behaviours (patient survey) and willingness to support patient involvement (healthcare professional survey) on a scale of 1-7.</p><p><strong>Participants: </strong>One hundred and ten patients who had received a transfusion aged between 18 and 93 (60 male) and 123 healthcare professionals (doctors, nurses and midwives) involved in giving blood transfusions to patients.</p><p><strong>Results: </strong>Mean scores for patients' willingness to participate in safety-relevant transfusion behaviours and healthcare professionals' willingness to support patient involvement ranged from 4.96-6.27 to 4.53-6.66, respectively. Both groups perceived it most acceptable for patients to help prevent errors or omissions relating to their hospital identification wristband. Neither prior experience of receiving a blood transfusion nor professional role of healthcare staff had an effect on attitudes towards patient participation.</p><p><strong>Conclusion: </strong>Overall, both patients and healthcare professionals view patient involvement in transfusion-related behaviours quite favourably and appear in agreement regarding the behaviours patients should adopt an active role in. Further work is needed to determine the effectiveness of this approach to improve transfusion safety.</p>","PeriodicalId":442504,"journal":{"name":"Transfusion Medicine (Oxford, England)","volume":" ","pages":"251-6"},"PeriodicalIF":1.5,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-3148.2012.01149.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40169659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}