Sante Mentale au Quebec最新文献

{"title":"[The data and metadata repository of the Québec Mental Health Alliance].","authors":"Arina Ujevco, Cécile Le Page, Marc Corbière, Stéphane Guay, Martin Lepage, Marc Hébert, Robert-Paul Juster, Enzo Cipriani, Charles-Édouard Giguère, Lionel Cailhol, Pierre Orban, Stéphane Potvin, Andrée-Ann Baril, Thomas Beaudry, Sophie Blais-Michaud, Mallar Chakravarty, Alyssa Dai, Simon Ducharme, Pierre Marquet, Clara Morin, Naguib Mechawar, Jean-Baptiste Poline, Martin Roy, Claudia Savard, Sebastian Urchs, Vincent Taschereau-Dumouchel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objectives In the era of artificial intelligence, our understanding of mental health challenges depends heavily on our ability to generate and analyze large-scale datasets. Accordingly, the Data Valorization Axis of the Québec Mental Health Alliance (ASMQ) was established in 2024 to create a comprehensive repository of open mental health data and metadata in Québec. This initiative's mandate is to facilitate the indexing and discoverability of data and metadata collected in Québec, notably at the 3 main mental-health research centers of the Fonds de recherche du Québec: the Centre de recherche de l'Institut universitaire en santé mentale de Montréal (CR-IUSMM), the Centre de recherche CERVO and the Centre de recherche Douglas. Methods To build the Alliance repository, researchers and clinicians at ASMQ affiliated institutions were directly invited to index the datasets available in their laboratories. Nine databases were identified, and some are currently accessible via online-sharing platforms: Neurobagel, Maelstrom, and the Atlas of Longitudinal Datasets. Here, we present a description of the data contained in the various databases. Results To date, the data and metadata of 11,570 participants (26% psychosis and schizophrenia, 21% personality disorder, 19% mood disorder, 12% substance use, 10% bipolar disorder, 9% anxiety disorder) across 8 biobanks and datasets have been shared online through the Alliance repository. The biobank metadata includes various demographic (e.g. age, sex, gender, level of education), medical (e.g. psychiatric and physical diagnoses, medication use), psychosocial (e.g. social functioning, quality of life, depressive symptoms), anthropometric (e.g. height, weight), metabolic, behavioral (e.g. sleep, consumption of non-food products), cognitive (e.g. performance on neurophysiological tests), and medical-imaging data. Additionally, general information on governance and procedures for accessing and contributing new data to the repository is provided. Impact The Québec Mental Health Alliance repository enhances the visibility and accessibility of mental-health data in Québec, facilitating the sharing and dissemination of domain-specific data and metadata. The repository also aims to facilitate the harmonization of access procedures and experimental protocols. By advancing open science in Québec, the Alliance repository can catalyze scientific breakthroughs that rely on the analysis of large-scale datasets. This initiative could eventually be extended to other health institutions across Québec.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"205-232"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated, Neuronavigated Neuromodulation for Negative Symptoms in Schizophrenia: Protocol for a Randomized Controlled Pilot Trial.","authors":"Ashley Choucroun, Olivier Roy, Stéphane Potvin, Lena Palaniyappan, Nadia Zeramdini, Aryamman Aiyaar, Katherine Picard, Samaneh Zanjani, Deven Parekh, Mariza Markessinis, Timothy Friesen, Tihare Zamorano, Andreea Diaconescu, Martin Lepage, Albert Powers, Jai Shah, Elissa Zavaglia, David Benrimoh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Background Negative symptoms (NS) of schizophrenia, including avolition, anergia, and social withdrawal cause major functional impairment and have limited treatment options. Repetitive transcranial magnetic stimulation (rTMS) targeting the left dorsolateral prefrontal cortex (LDLPFC) shows promise in alleviating NS, though response remains modest, and multi-week protocols are often burdensome. A five-day, high-dose intermittent theta burst stimulation (iTBS) protocol using fMRI-guided neuronavigation has demonstrated rapid and sustained effects in major depression. Given the overlap between depressive lassitude and NS domains, accelerated neuronavigated iTBS may hold promise in schizophrenia with NS. Methods This multisite, randomized, patient- and rater-blinded trial evaluates the feasibility, safety, and preliminary efficacy of such a protocol in individuals with schizophrenia spectrum disorders. Seventy-five adults with clinically significant NS will receive either: (1) neuronavigated active iTBS targeting LDLPFC regions most anti-correlated with the subgenual anterior cingulate cortex (sgACC) (2) non-neuronavigated active iTBS using scalp-based coordinates; or (3) neuronavigated sham stimulation over 10 daily sessions spanning 5 consecutive days (90,000 pulses total), with follow-ups at 1 week, 1 month, and 3 months. Résultats Outcomes include a reduction in NS; Efficacy comparisons between neuronavigation and non-neuronavigation; Feasibility and safety; Change in social and affective information processing; Change in depressive symptoms. Conclusion Results will inform future trials, while comparison of targeting strategies will clarify the utility of neuronavigation. If successful, this trial will offer a time-efficient, personalized intervention for NS.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"233-250"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Post-traumatic stress injuries in firefighters: The differential role of critical incident types].","authors":"Constance Boulé, Stéphane Guay, Eugénie Samson-Daoust, Steve Geoffrion","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objectives Firefighters are repeatedly confronted with critical incidents (CIs) at work, which are events that significantly disrupt an individual's normal functioning (e.g. failed interventions, serious accidents, media criticism). Repeated exposure to such incidents increases their vulnerability to developing post-traumatic stress injuries (PTSIs). In Canada, approximately 30% of firefighters meet the clinical thresholds for at least one PTSI; the most commonly observed being depression, post-traumatic stress disorder (PTSD), anxiety, alcohol use, and suicidal ideations. The objectives of this study are to 1) describe the frequency of CIs that firefighters encounter at work and 2) identify the different types of CIs associated with PTSIs. Method This research is based on secondary use of cross-sectional data collected in 2018 as part of a partnership with a Quebec fire department. In this context, 690 firefighters responded to a survey designed to assess their overall psychological health. Participants reported on the CIs they had experienced during their careers. Standardized questionnaires were used to measure symptoms of depression, generalized anxiety, post-traumatic stress disorder, alcohol use disorder, substance use, and suicidal ideations. Results The results indicate that rare and serious incidents, particularly critical equipment failure, are strongly linked to various PTSI, while frequent incidents are associated with generalized anxiety and depression. Negative media criticism also appears to be a major stress factor associated with several PTSIs. Conclusion Given firefighters' increased vulnerability to PTSIs, this study highlights the importance of considering the diversity of CIs encountered at work as well as the influence of contextual factors such as media criticism. It also emphasizes the need for transdiagnostic approaches and intervention measures rooted in the professional reality of these workers to better support their mental health.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"101-124"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The Professional Peer-Supporter: An Emerging Lever for Mental Health at Work].","authors":"Imaine Sahed, Siham Sahed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mental health in the workplace represents a growing challenge at the intersection of performance imperatives and well-being. Facing the limitations of traditional psychosocial risk prevention frameworks, the figure of the professional peer-supporter is emerging, grounded in the valuation of experiential knowledge as an intervention resource. By mobilizing their lived experience of distress or recovery, these hybrid actors support their colleagues, foster the recognition of lived experiences, and contribute to the cultural transformation of organizations. Drawing on French and Canadian contexts, this study highlights the potentialities and tensions inherent in this role: professionalization, institutional recognition, ethical issues, and the risks of instrumentalization. Thus, the professional peer-supporter appears as a strategic lever for social innovation, promoting a participatory and inclusive approach to mental health at work, yet requiring further empirical and ethical consolidation to be sustainably embedded in professional practices.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"289-297"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Towards the development of technologies to improve clinical decision-making: The example of Tadeus].","authors":"Marc J Lanovaz, Johana Monthuy-Blanc","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although new technologies and artificial intelligence promise to improve mental health care, few scientifically validated applications are available, particularly in French. To address this issue, Centre de recherche de l'Institut universitaire en santé mentale de Montréal founded the Axel Center to accelerate the digital health strategy and to facilitate technological innovation for mental health research and care. The Axel Center thus addresses a tripartite ecosystem composed of research, clinical practice, and entrepreneurship. The purpose of this article is to introduce an example of an application developed in collaboration with the Axel Center and to present how the center can meet the needs of research teams. This example is Tadeus, a bilingual web application that allows mental health specialists and their partners (e.g. family members, caregivers, service recipients) to enter and share data to more rigorously monitor mental health interventions. In addition to presenting the application, the article discusses the challenges that can arise in the development, sustainability and dissemination of such applications, as well as how the Axel Centre can support research teams in overcoming these challenges.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"153-164"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Allostatic Load and Transdiagnostic Dimensions in Patients Admitted to the Psychiatric Emergency Department: A Research Protocol Using the Signature Biobank].","authors":"Robert-Paul Juster, Cécile Le Page, Nevena Chuntova, Enzo Cipriani, Clara Morin, Claudia Trudel-Fitzgerald, Marie-France Marin, Ahmed Jerome Romain, Steve Geoffrion, Stéphane Guay, Vincent Taschereau-Dumouchel, Stéphane Potvin, Naguib Mcchawar, Caroline Ménard, Eugénie Samson-Daoust, Charles-Édouard Giguère, Janick Boissonneault, Helen Findlay, Jasmine Boulette, Michelle Lonergan, Bahram Armoon, Alain Lesage, Alexandre Hudon, Christophe Longpré-Poirier, Emmanuel Stip","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective People in acute crisis who seek psychiatric emergency services are clearly in great distress and likely already show signs of chronic stress. But how can we best measure chronic stress physiologically? Our study aims to assess allostatic load (AL), the \"wear and tear\" on biological systems that we can measure using different biological marker called biomarkers. Method We aim to assess biological and psychosocial dimensions related to psychiatric symptom changes among psychiatric emergency patients repeatedly evaluated at four-time points: (T1) 48-hours upon admission, (T2) end of hospitalization (about 2 weeks later), (T3) external follow-up (about 2 months), and (T4) 1 year later. We expect that (1) AL at T1 will distinguish psychiatric conditions, (2) higher AL will predict symptom trajectories over time, and (3) that combinations of modifiable risk and protective factors (e.g. health-related behaviors, psychosocial experiences) will boost or buffer these associations. We acquired funding in order analyze hair, saliva, and blood samples that have already been collected as part of the Signature Biobank that offers measures at T1 (N=1,984; 40% women; mean age 41 with a range from 18-81) as well as at T2 (n=685), T3 (n=606), & T4 (n=370). Results In the proposed project, we acquired funding to analyze biobanked tissues to index AL among all PEP and 149 healthy controls. Among subsamples with T2, T3, and T4 measures, we will assess prospectively changes in AL and psychiatric symptoms trajectories simultaneously. Conclusion From admission to remission, the study of psychiatric emergency patients is a unique opportunity to assess extreme profiles that can help refine precision medicine. The Signature Biobank will provide unique insights on the biological signatures of psychiatric conditions and changes over time while also providing unique knowledge and training opportunities for years to come supported by a transdisciplinary team.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"165-195"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Reinventing Care: Collaborative Innovation at the Heart of Mental Health Between Interdisciplinary Practices and the Voices of Patient Partners].","authors":"Novembre Mercier, Jillian Mills","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Collaboration with patient partners (PP) in mental health has become an essential practice, spurred by public policy and participatory research methods. Alliance en Santé Mentale du Québec, inspired by the principles of open science, actively promotes this involvement within the Centre de recherche de l'Institut universitaire en santé mentale de Montréal (CR-IUSMM). To mark the occasion of the CR-IUSMM's 30th anniversary, a committee of PPs conducted a series of interviews with key stakeholders involved with the Centre to explore their experiences, challenges, and perspectives regarding the patient-research partnership. In this article, we highlight the transformations and lessons learned from these collaborations.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 2","pages":"263-268"},"PeriodicalIF":0.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Schizo-obsessive disorder in a South Asian context: A case report highlighting religious obsessions and psychosis.","authors":"Rahemeen Yusuf, Rabia Munir, Asad Tamizuddin Nizami, Ifrah Javed Malik, Mahadd Asad Nizami, Syed Fahad Javaid","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Background The co-occurrence of schizophrenia and obsessive-compulsive disorder has attracted increasing clinical and research attention, yet it is not recognised as a distinct diagnostic entity in current psychiatric classification systems. This overlap is associated with greater symptom severity, increased suicide risk, and poorer treatment outcomes. Despite its clinical relevance, reports from South Asia remain scarce. This case contributes regional data and supports the conceptualisation of a schizo-obsessive subtype, challenging existing nosological boundaries. Case Presentation We report the case of a 29-year-old man with progressive social withdrawal, persecutory beliefs, and second-person auditory hallucinations. Symptoms emerged insidiously following a relational stressor and included religious-themed command hallucinations leading to a suicide attempt. Concurrently, he experienced intrusive, ego-dystonic religious images during prayer, accompanied by compulsive hand-washing and mental neutralising rituals related to blasphemous fears. There was no history of prior psychiatric treatment, substance use, or neurological illness. Mental state examination and structured assessments supported a diagnosis of schizophrenia with co-morbid moderate obsessive-compulsive symptoms. Treatment with olanzapine, followed by escitalopram, resulted in symptomatic improvement. Exposure and response prevention therapy showed sustained benefit in follow-up. Conclusions This case highlights the clinical importance of recognising co-occurring schizophrenia and obsessive-compulsive symptoms, regardless of medication or neurological issues. Prominent religious themes suggest considering cultural and religious contexts, especially in highly religious societies. As a rare detailed report from Pakistan, it provides valuable regional data and indicates schizo-obsessive presentations may be under-recognised in South Asia. Recognising this profile can improve diagnosis, foster culturally sensitive treatments, and encourage further research.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 1","pages":"105-117"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[When virtual reality gives voice to silence: A case report of a patient with schizoaffective disorder and progressive bilateral deafness treated with Avatar therapy].","authors":"Laetitia Stip, Sabrina Giguère, Julie-Manon Deslongchamps, Kingsada Phraxayavong, Alexandre Dumais","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Auditory verbal hallucinations (AVH) are a common and often debilitating symptom of psychotic disorders. Despite pharmacological treatments, approximately 30% of patients continue to experience resistant AVH. Avatar therapy (AT), a virtual reality therapy, is an innovative approach aimed at changing the relationship between the patient and their voices. This case report describes the clinical course of a 72-year-old man with schizoaffective disorder and bilateral hearing loss with almost total deafness in the right ear, who reported AVH in both ears, but more intense on the right side. This atypical clinical presentation raises specific issues regarding the understanding of perceptual mechanisms and the adaptation of therapeutic interventions. The patient participated in a AT protocol consisting of nine weekly sessions at the Montreal University Institute of Mental Health. Pre- and post-therapy clinical assessments showed a significant decrease in the frequency and distress associated with AVH, improved emotional regulation and quality of life, and an overall reduction in psychiatric symptoms. Clinical interviews confirmed a greater sense of control and a less threatening relationship with the voices. This case highlights the potential of AT in patients with sensory impairments and emphasises the importance of personalised therapeutic approaches that incorporate immersive technologies in mental health.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 1","pages":"175-188"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quand la singularité fait science : les kèzes riportes (case report) en santé mentale : aux frontières du clinique : cas rares, pratiques innovantes et savoirs émergents.","authors":"Emmanuel Stip","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"51 1","pages":"17-24"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}