Archives of Otolaryngology and Rhinology最新文献

{"title":"Errors in the Assumptions of Bekesy's Traveling Wave Theory","authors":"Myjkowski Jan","doi":"10.17352/2455-1759.000154","DOIUrl":"https://doi.org/10.17352/2455-1759.000154","url":null,"abstract":"This article examines the fundamental statements of Bekesy's traveling wave theory in hearing and proposes an updated perspective on auditory information processing mechanisms. It argues that the traditional theory does not adequately account for non-mammalian auditory mechanisms, as many species effectively perceive sound without a basilar membrane or cochlear fluids. It suggests alternative pathways for sound signal reception directly to the receptor, bypassing traditional structures like the basilar membrane. This reevaluation raises significant doubts about the resonance capability and the actual role of the basilar membrane in hearing, suggesting that current understandings of auditory processing may be fundamentally limited and not universally applicable across different species.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"106 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141820362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profiling ACE2 and TMPRSS2 expression in sinonasal mucosa","authors":"Price Michael E, Nallani Rohit, Bodine Jared S, Gaur Gunjan, Arnold Levi, Humphrey Bryan, Ottemann Brendan, O’Neil Maura F, Sykes Kevin J, Beahm D David, Qiu Jianming, Chiu Alexander G, Thomas Sufi Mary","doi":"10.17352/2455-1759.000148","DOIUrl":"https://doi.org/10.17352/2455-1759.000148","url":null,"abstract":"Rhinologists may be one of the highest-risk subspecialties in otolaryngology for exposure to SARS-CoV-2 as the sinonasal passage seems to be a reservoir for the virus. Previous data indicate nasal epithelial cells express the primary receptor for SARS-CoV-2, Angiotensin-Converting Enzyme-2 (ACE2). However, no data exist profiling the regional expression of ACE2 or the expression of transmembrane serine protease 2 (TMPRSS2), an additional protease necessary for SARS-CoV-2 viral entry, within the sinonasal cavity. We sought to assess for anatomic expression of ACE2 and TMPRSS2 throughout the nasal cavity and paranasal sinuses. We hypothesize that ACE2 and TMPRSS2 are expressed throughout the nasal cavity and paranasal sinuses. To test this hypothesis, we sampled various regions of the sinonasal cavity from patients undergoing rhinology procedures and used immunohistochemical staining to profile ACE2, compare ACE2 expression between regions, and compare ACE2 expression between patients and patient characteristics. We found ACE2 and TMPRSS2 are present throughout the sinonasal cavity without a regional pattern among anatomic regions in our patients. We found no statistically significant correlation in ACE2 expression with patient characteristics such as age, sex, or BMI. We also did not find a statistically significant correlation between ACE2 and TMPRSS2 quantitative expression. ACE2 expression trended higher in males compared to females for six out of seven regions excluding the nasal floor. In conclusion, ACE2 and TMPRSS2 are expressed ubiquitously throughout the sinonasal cavity. ACE2 expression may be higher in the sinonasal cavity in males compared to females. These data implicate that SARS-CoV-2 is unlikely to discriminate between anatomic regions as a point of entry and that anatomic regions likely are similar in viral load. Thus, all rhinology and skull base surgeries, independent of encounter of the anatomic region in the sinonasal cavity, predicate screening for SARS-CoV-2, and necessary personal protective equipment.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129192810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of smell exercise after smell dysfunction related to COVID-19 in Alahsaa, Saudi Arabia","authors":"A. Khalid A, Aldrweesh Abdulrahman Khalid, Aldoughan Alghaydaa Fouad, Alarfaj Sumaia Mohammed, Alabdulqader Fatimah Khalid, A. Abdullah A","doi":"10.17352/2455-1759.000147","DOIUrl":"https://doi.org/10.17352/2455-1759.000147","url":null,"abstract":"Introduction: Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome. Globally, COVID-19 has infected more than 573 million people, with over 6.3 million deaths on July 27, 2022. The symptoms range from cold-like symptoms, cough, fever, shortness of breath, and sore throat; additionally, studies show that patients frequently have problems with smell and taste disorders (STD). Aim: We aim to estimate the prevalence of COVID-19-related anosmia, hyposmia, and parosmia in Alahssa, Saudi Arabia and establish the level of awareness of smell exercises. Patients and methods: This is a cross-sectional study conducted among adults aged 18–60 living in Alahssa, Saudi Arabia. An online questionnaire containing an informed consent form and a survey to collect demographic data, vaccination status, level of loss of smell and taste, and the level of awareness about smell exercises was distributed among all participants who agreed to participate in this study. Results: Five hundred twenty-four adults agreed to participate in this study. When we assessed their awareness of the smelling exercise, it was found that only 115 patients (21.9%) were aware. About 49 patients (61.3%) practiced the smelling exercise, and 55% reported improvements afterward. Conclusion: The prevalences of olfactory and gustatory dysfunction were found to be 54.6% and 52.5%, respectively. Awareness of olfactory training was moderately low among those infected with COVID-19, while 28% of the patients who had experienced olfactory disturbances were aware of this training. Active, collaborative research is essential for describing the natural history and effective therapy of chemosensory impairment in COVID-19.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128048048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of smoking on status of hearing: A cross-sectional study","authors":"Gautam Nandita, K. Shivalingesh, Kushwaha Anushtha, Singh Varnika, Singh Siddhant, Kumar Shashank","doi":"10.17352/2455-1759.000146","DOIUrl":"https://doi.org/10.17352/2455-1759.000146","url":null,"abstract":"Introduction: Smoking is a common tendency among all social classes around the globe, especially in the working population. Objective: To assess the significant link between tobacco and cigarette smoking and its effect on hearing among smokers as there is limited study on this aspect of the Indian population particularly with a high-frequency hearing threshold. Methodology: Cross-sectional study carried out on patients attending the OPD in ENT and Head & Neck Surgery Department of Rohilkhand Medical College & Hospital. The sample size came to be 90. Results: In smokers, there were 72 (80%) males and 18 (20%) females while in the non-smoker group, there were 53 (58.8%) males and 37 (41.11%) females, and 39 (43.3%) subjects belonging to the rural population while 51 (56.7%) subjects belong to an urban population. out of 90 subjects, 43 (30.3%) had cochlear deafness followed by 40 (28.2%) who had normal hearing and 7 (4.9%) had retrocochlear deafness. Conclusion: Tobacco has the power to reduce the ability to hear, mainly causing a sensorineural hearing loss at higher frequencies.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123160894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remarks on the theory of hearing-a traveling wave part two","authors":"Myjkowski Jan","doi":"10.17352/2455-1759.000145","DOIUrl":"https://doi.org/10.17352/2455-1759.000145","url":null,"abstract":"In the paper, attention was paid to the procedure of reception and transforming auditory information, which does not comply with Bekesy’s traveling wave theory. This concerns the sound reception below the hearing threshold in some animals and birds. Discussed are some issues related to the traveling wave theory with an explanation of directional hearing. Indicated was a possibility of reception, especially, of high frequencies, directly on the receptor, without the basilar membrane, due to the conduction of sound waves through soft tissues and a bone.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125052069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of olfactory training program in conjunction with nasal steroid irrigation in treating persistent smell loss in COVID-19 patients","authors":"A. Marwa, Ali Elkholi Safaa Mostafa","doi":"10.17352/2455-1759.000144","DOIUrl":"https://doi.org/10.17352/2455-1759.000144","url":null,"abstract":"Background: Smell loss is a challenging clinical problem. There is still no evidence-based medical intervention to treat patients with persistent smell loss as a result of Coronavirus Disease 2019 (COVID-19). The aim is to analyze the efficacy of treating patients with persistent smell loss due to COVID-19 using olfactory training (OT) combined with nasal steroid irrigation. Methods: A cross-sectional study enrolled 196 COVID-19 patients with persistent smell loss were recruited. All patients underwent two testing sessions. At the first session, patients were examined by a history taking followed by an Otorhinolaryngological examination including, a thorough nasal endoscopy. In addition, an olfactory performance assessment was performed to assess the severity of smell loss. All patients were then treated with OT and nasal steroid irrigation with budesonide for 12 weeks. The second session includes an olfactory performance assessment to assess if there is an improvement in olfactory function. Results: Patients after treatment showed improvement in overall Threshold-Detection-Identification (TDI) score, odor detection threshold score, odor discrimination score, and odor identification score, which were higher than before treatment. Statistically significant differences before and after treatment results were very pronounced for the overall TDI score (p = 0.014) and odor detection threshold score (p = 0.003). There was no significant difference in odor discrimination (p = 0.08) or odor identification (p = 0.126) scores before and after treatment. Conclusion: The results of this study support the efficacy of the combination of budesonide nasal irrigation and OT in treating persistent smell loss due to COVID-19 infection.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116029943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of the pathophysiology of chronic mucosal diseases of allergic rhinitis, asthma and otitis media as seen by an otolaryngologist","authors":"Hurst David S, McDaniel Alan B","doi":"10.17352/2455-1759.000143","DOIUrl":"https://doi.org/10.17352/2455-1759.000143","url":null,"abstract":"Otolaryngologists, like Pediatricians, often see patients with chronic rhino-sinusitis and draining ears. Surgeons can offer various procedures, from simple tympanostomy tubes to advanced sinus and turbinate operations, in which significant portions of bone and mucosa are removed. The rates of reinfection are often reduced [1] but failures occur.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"44 37","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120865042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial laryngeal tumor “embolus”creating respiratory difficulty during surgery: A case report","authors":"Ray Dieter","doi":"10.17352/2455-1759.000142","DOIUrl":"https://doi.org/10.17352/2455-1759.000142","url":null,"abstract":"Unusual laryngeal and tracheobronchial obstructing lesions are seen on occasion [1-3]. A patient was evaluated by his primary physician and pulmonologist due to symptoms referable to his chest including a cough and shortness of breath. Evaluation, including lexible bronchoscopy, revealed a primary carcinoma of the left upper lobe of the long.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130639230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of mode of presentation and mode of speech on listener perceptions of voice, speech and personality following supracricoid laryngectomy","authors":"Paul M. Evitts, Heather M. Starmer, Kim Webster","doi":"10.17352/2455-1759.000138","DOIUrl":"https://doi.org/10.17352/2455-1759.000138","url":null,"abstract":"There is a paucity of information on listener perceptions of Individuals with a Laryngectomy (IWL) based on different modes of speech, in particular, speech following Supracricoid Laryngectomy (SCL).","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128053992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of sinusitis associate with filling material of the maxillary sinus by endonasal endoscopic sinus surgery simultaneous sinus-lifting and dental implantation","authors":"G. Hakobyan, G. Khachatryan, L. Khachatryan, L. Yessayan, Davit Mathevosyan","doi":"10.17352/2455-1759.000136","DOIUrl":"https://doi.org/10.17352/2455-1759.000136","url":null,"abstract":"Optimization of the sinus-lifting in patients with filling material in maxillary sinus cavity by a one-stage endonasal endoscopic elimination of the sinus pathology and carrying out a sinus-lifting.","PeriodicalId":440305,"journal":{"name":"Archives of Otolaryngology and Rhinology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128185178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}