Journal of Mind and Medical Sciences最新文献

Prevalence of depression, anxiety and stress after the COVID-19 pandemic period among students at the Medical University of Sofia; Significance of demographic, educational, and pandemic-related variables 索菲亚医科大学学生在2019冠状病毒病大流行期后抑郁、焦虑和压力的流行情况人口统计、教育和流行病相关变量的重要性

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1376

Nadya Avramova

{"title":"Prevalence of depression, anxiety and stress after the COVID-19 pandemic period among students at the Medical University of Sofia; Significance of demographic, educational, and pandemic-related variables","authors":"Nadya Avramova","doi":"10.22543/2392-7674.1376","DOIUrl":"https://doi.org/10.22543/2392-7674.1376","url":null,"abstract":"This cross-sectional study aimed to determine the prevalence of depression, anxiety, and stress among undergraduate dental students at Sofia Medical University and to investigate its associations with some demographic, educational and pandemic-related variables. A self-reported questionnaire that included the validated DASS-21 scale was administered to a group of 2nd, 3rd, 4th, and 5th year students (n=70, response rate 95.7%). Results indicated abnormal levels of depression, anxiety, and stress in 34.3%, 65.7% and 59.7% of the participants, respectively. A much larger proportion of females suffered from abnormal levels of anxiety (56.6%) as compared with males (9%), p=.003. Single students exhibited significantly higher level of depression (25.4%) than those having a partner (9%), p=.037. Third-year dental students demonstrated higher level of depression (19.4%) compared to 5th year students (1.5%), p=.007 as well as higher stress scores (25.4%) than 2nd year students (17.9%), p=.035. Academic performance (assessed by GPA in this study), dentistry as the first students’ choice when applying for MUS, financial responsibilities, and pandemic-related academic responses were not found significant factors for depression, anxiety, and stress (p>.05). These outcomes highlight the need to provide psychological support programs with special attention on susceptible groups. Dental students should implement preventive measures and adopt coping strategies to manage stress and reduce levels of anxiety and depression.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135928521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcopenic obesity, pathogenesis, and treatment with a focus on exercise and protein intake 肌肉减少性肥胖，发病机制和治疗的重点是运动和蛋白质摄入

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1419

Yasemin Karaağaç

引用次数: 0

Sentinel node biopsy for personalized breast cancer management; advances and controversies 前哨淋巴结活检的个体化乳腺癌管理;进步与争议

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1440

Rahim Al Moushaly, Daniel Ion, Octavian Andronic, Bogdan Socea, Alexandru Cosmin Palcau, Dan Nicolae Paduraru

{"title":"Sentinel node biopsy for personalized breast cancer management; advances and controversies","authors":"Rahim Al Moushaly, Daniel Ion, Octavian Andronic, Bogdan Socea, Alexandru Cosmin Palcau, Dan Nicolae Paduraru","doi":"10.22543/2392-7674.1440","DOIUrl":"https://doi.org/10.22543/2392-7674.1440","url":null,"abstract":"Sentinel lymph node biopsy (SLNB) has become the gold standard for axillary lymph node staging, providing valuable prognostic information while minimizing complications compared to axillary lymph node dissection. However, there are ongoing debates and controversies surrounding SLNB in specific cases. Studies have explored the use of SLNB in neoadjuvant chemotherapy, emphasizing the need for customized therapy decisions. Factors such as age, tumor characteristics, and treatment response influence the selection of SLNB or axillary lymph node dissection. Additionally, the presence of extranodal extension, micrometastases, and isolated tumor cells has been evaluated to determine the need for lymphadenectomy. The importance of accurate oncological staging by thorough pathological evaluation has been highlighted, particularly with regards to invasion depth and lympho-vascular invasion. The significance of biological tumor status, such as hormone receptor and HER2 status, in axillary management decisions has been emphasized. Moreover, discussions have emerged regarding SLNB in the context of local recurrence, with differing perspectives on its utility. Future extensive studies are needed to refine protocols and incorporate these concepts related to SLNB into breast cancer management guidelines.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"19 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Follow-up care after metabolic surgery – a prospective study in the North-Eastern region of Romania 代谢手术后的随访护理——罗马尼亚东北地区的一项前瞻性研究

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1415

Sorina Boariu, Ana Maria Scutariu, Adrian Cureniuc, Anamaria Meuca, Roxana Adriana Stoica, Anca Mihaela Pantea Stoian, Delia Reurean Pintilei

{"title":"Follow-up care after metabolic surgery – a prospective study in the North-Eastern region of Romania","authors":"Sorina Boariu, Ana Maria Scutariu, Adrian Cureniuc, Anamaria Meuca, Roxana Adriana Stoica, Anca Mihaela Pantea Stoian, Delia Reurean Pintilei","doi":"10.22543/2392-7674.1415","DOIUrl":"https://doi.org/10.22543/2392-7674.1415","url":null,"abstract":"Background. Anti-obesity therapeutic strategies are continuously evolving. Bariatric procedures or metabolic surgery are among the most effective and long-lasting therapies for obesity and its complications. Our objective was to investigate the clinical and biological evolution after metabolic surgery in a group of patients from North-Eastern Romania and to evaluate a nutritional intervention plan for this population. Materials and Methods. Our clinic surveyed 50 patients who received nutritional counselling before and after bariatric surgery. The patient's weight loss, metabolic markers, and lifestyle changes from January to December 2021 were recorded. SPSS Statistics v.18 was used for statistical analyses. Results and Discussions. Patients had a mean age of 37.70 ± 11.38 years, with an initial body mass index (BMI) of 42.98 ± 6.12 kg/m2. One month after surgery, longitudinal gastrectomy patients lost 12.6 kg (114.33 ± 19.26 vs 101.73±17.27 kg), and gastric bypass patients lost 10.86 kg (119.33 ± 20.83 vs 108.47±17.96 kg). Body composition improved in the first six months after the intervention due to adipose (mean value 37.83±6.42 from 46.38±6.63) and visceral (mean value 8.50 ± 4.42 from 13.72±5.67) tissues decrease. Muscle tissue increased from 35.54±12.63 to a mean value of 39.95±17.96. HbA1c values improved from 5.90±0.63% to 5.30±0.30% in the first month after the intervention. The nutritional intervention was safe without significant deficits after 1 and 6 months. Conclusions. Metabolic surgery is associated with a weight loss of 10.8 to 12.6 kg and improved body composition. Patients require follow-up and further dietary counseling to sustain long-term results.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant renal cell carcinoma in a patient with ipsilateral lower limb hypertrophic lichen planus; Case report and literature review 巨肾细胞癌伴同侧下肢增生性扁平苔藓1例病例报告及文献复习

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1425

Silvia Popescu, Dumitru Peța, Zoltan Janos Kövér, Dumitru Toma, Ioan-Teodor Cristea, Mihaela Anca Popescu, Oana-Denisa Bălălău, Romina-Marina Sima, Gabriel-Petre Gorecki, Călin Giurcăneanu

{"title":"Giant renal cell carcinoma in a patient with ipsilateral lower limb hypertrophic lichen planus; Case report and literature review","authors":"Silvia Popescu, Dumitru Peța, Zoltan Janos Kövér, Dumitru Toma, Ioan-Teodor Cristea, Mihaela Anca Popescu, Oana-Denisa Bălălău, Romina-Marina Sima, Gabriel-Petre Gorecki, Călin Giurcăneanu","doi":"10.22543/2392-7674.1425","DOIUrl":"https://doi.org/10.22543/2392-7674.1425","url":null,"abstract":"Renal cell carcinoma is the most common type of primary urogenital cancer, usually resistant to radiotherapy and chemotherapy. Hypertrophic lichen planus is an inflammatory dermatosis characterized by the presence of papulosquamous and intensely pruritic lesions. The association of these two conditions is unusual, being reported in the specialized literature only in a few rare cases with the onset of lichenoid lesions after patients have undergone various forms of treatment. The case of a 62-year-old male patient who was admitted for severe abdominal pain due to a giant renal tumor associated with a hypertrophic plaque located on the anterior part of the left calf is presented. After (clinical, biochemical, imaging) diagnosis, surgery was performed for en bloc removal of the entire mass, adrenal gland, and spleen. The histopathological exam established the diagnosis of a moderately differentiated T2b clear cell Grawitz tumor, without regional lymph node metastasis (stage II). The patient continued local corticosteroid therapy in the hospital for hypertrophic lichen planus lesions, being referred to the oncology department after discharge.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"66 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of inflammation in age-related macular degeneration 炎症在老年性黄斑变性中的作用

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1421

Diana Florina Tricorache, Ana Maria Dascalu, Crenguta Serboiu, Anca Bobirca, Dragos Cretoiu, Dan Bratu, Corneliu Tudor, Laura Carina Tribus

引用次数: 0

Prevalent distribution of conscious processes on either side of the brain 意识过程在大脑两侧的普遍分布

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1382

Sohail Adnan, Mubasher Shah, Muhammad Fateen Rashed, Sadaf Nawab

{"title":"Prevalent distribution of conscious processes on either side of the brain","authors":"Sohail Adnan, Mubasher Shah, Muhammad Fateen Rashed, Sadaf Nawab","doi":"10.22543/2392-7674.1382","DOIUrl":"https://doi.org/10.22543/2392-7674.1382","url":null,"abstract":"Objectives. The brain has an intrinsic tendency for the lateralization of its functions. For instance, the left hemisphere assists in the comprehension and motor expression of language. What remains uncertain is whether conscious processes are also more prevalent in one hemisphere of the brain than the other. The epistemic goal of this research was to address this particular issue. Materials and Methods. We observed the rare pathological event of proximal occlusion of the middle cerebral artery (MCA), which halts blood flow to the central two-thirds of a hemisphere, and examined its effects on consciousness. We aggregated individual scores for eyes-opening and limb-motor responses from the Glasgow Coma Scale (GCS) to determine the conscious level, and used brain computed tomography imaging to identify the whole-territory infarcts of MCA. Results. Being a rare condition, we managed to recruit 35 patients from two centers (average age: 64.54 ± 13 years, 45.71% females). Whole-territory infarcts of the MCA occurred more frequently in the left hemisphere (22 versus 13, frequency: 62.85%). Unconsciousness was also more common with left hemisphere infarctions (16 versus 2 unconscious patients of the right hemisphere, Frequency: 72%, GCS: 2/10=3/22 cases, GCS: 5/10=1/22 cases, GCS: 6-7/10=12/22 cases). The difference in unconsciousness proved significant in Fisher’s exact analysis (p-value = 0.001) and remained independent of age (p-value=0.7247) and gender (p-value=0.3145). Moreover, six conscious patients with left hemisphere involvement exhibited a loss of conscious control for normal responses, implying a strong link between consciousness and cognition. Unconsciousness also correlated with stroke outcomes (16 Unconscious: 56.25% deceased within the hospital). Conclusion. Conscious processes are more predominant in the brain's left hemisphere. Our observations indicate that only a gross unilateral insult to the brain can lead to unconsciousness.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric cancer; actualities and perspectives of early diagnosis and targeted therapy 胃癌;早期诊断与靶向治疗的现状与展望

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1444

Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Anca Dumitriu, Stana Paunica, Cristian Balalau, Stefăniță Tenea Cojan, Dragos Epistatu, Vlad Denis Constantin

{"title":"Gastric cancer; actualities and perspectives of early diagnosis and targeted therapy","authors":"Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Anca Dumitriu, Stana Paunica, Cristian Balalau, Stefăniță Tenea Cojan, Dragos Epistatu, Vlad Denis Constantin","doi":"10.22543/2392-7674.1444","DOIUrl":"https://doi.org/10.22543/2392-7674.1444","url":null,"abstract":"Gastric cancer is an extremely aggressive form of malignancy that, if left untreated, is life-threatening. Improved survival rates depend on early detection of the disease, as well as on the combination of different forms of treatment (surgery, chemotherapy, radiotherapy, immunotherapy, etc.). Screening methods have brought real benefit in early detection of malignancies, but many cases are still diagnosed at advanced stages. The current study is a review related to actualities and perspectives of early diagnosis and targeted therapy of gastric cancer. After an extensive review of the literature, epidemiological, diagnostic and treatment data are presented. The open surgical approach is used in emergency centers or with a low surgical activity, while the minimally invasive approach (laparoscopic, robotic) is possible in large centers dedicated to the treatment of gastric cancer. In the near future, new diagnostic and therapeutic tools are expected to appear, not only to cure cancer definitively, but also to be able to prevent it, if possible, without radically changing the lifestyle of the population.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135928524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Best therapeutic practices in the management of obstetric sepsis 产科败血症管理的最佳治疗方法

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1436

Gabriel Petre Gorecki, Oana Denisa Balalau, Diana Elena Comandasu, Anca Daniela Stanescu, Dana Rodica Tomescu

{"title":"Best therapeutic practices in the management of obstetric sepsis","authors":"Gabriel Petre Gorecki, Oana Denisa Balalau, Diana Elena Comandasu, Anca Daniela Stanescu, Dana Rodica Tomescu","doi":"10.22543/2392-7674.1436","DOIUrl":"https://doi.org/10.22543/2392-7674.1436","url":null,"abstract":"Background . Physiological changes that occur during pregnancy make maternal sepsis a difficult condition to diagnose and treat, still having a fairly high mortality rate. Consequently, an early diagnosis and prompt therapeutic management of sepsis can significantly decrease mortality. The purpose of this study is to review literature data that present current practices in the management of obstetric sepsis. Methods . To collect the data required for the study, we performed a search of published articles in the PubMed and Google Scholar databases related to obstetric sepsis. Research paper articles from the period 2012-2022 were included in the analysis. In addition, 145 articles from the period 2012-2022 were evaluated, with the aim of finding out in which situations the risk of maternal death is higher. Thus, the analysis included a total number of 151 articles, which were divided into two distinct stages. Results . The risk of maternal death is higher among patients with the human immunodeficiency virus (HIV), followed by Escherichia coli, genital tract infection, cancer, drug users and in the case of patients with chronic liver disease. Conclusions . After analyzing the data, we found that prompt and focused antibiotic therapy as well as fluid resuscitation are essential to increase the chances of survival of these patients.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subungual squamous cell carcinoma leading to arm amputation 甲下鳞状细胞癌导致手臂截肢

Journal of Mind and Medical Sciences Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1404

Ovidiu V Fabian, Emilia Maria Pătruţ, Mădălina Șteţca, Radu Mircea Galasiu, Vlad Zolog, Adriana Zolog, Iacob Domşa, Ioan Șimon, Anca Mihailov, Olga Hilda Orăşan, Flaviu Mureşan

{"title":"Subungual squamous cell carcinoma leading to arm amputation","authors":"Ovidiu V Fabian, Emilia Maria Pătruţ, Mădălina Șteţca, Radu Mircea Galasiu, Vlad Zolog, Adriana Zolog, Iacob Domşa, Ioan Șimon, Anca Mihailov, Olga Hilda Orăşan, Flaviu Mureşan","doi":"10.22543/2392-7674.1404","DOIUrl":"https://doi.org/10.22543/2392-7674.1404","url":null,"abstract":"Although rare, subungual carcinoma is the most common malignant nail tumor. The symptomatology is not characteristic, being very similar to that of other nail and periungual diseases. For this reason, early diagnosis is usually established by performing a biopsy. With appropriate treatment, subungual carcinoma usually has a favorable prognosis. Metastatic cases are rarely encountered, but they usually have a poor therapeutic result. This article presents the case of a patient with subungual carcinoma (diagnosed by histopathological exam), initially treated by amputation of the distal and middle phalanges of the fourth finger. Two years after the operation, a recurrence in the epitrochlear nodes was diagnosed, for which epitrochlear lymphadenectomy and postoperative chemotherapy were performed. At 7 months, metastases were detected in the axillary nodes, which were treated with radiotherapy and chemotherapy. The appearance and development of the tumor at the elbow and the lower third of the arm led the patient to accept scapulohumeral disarticulation. The patient finally adapted to the physical infirmity, having a good general condition and an optimistic attitude.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0