Subungual squamous cell carcinoma leading to arm amputation

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Ovidiu V Fabian, Emilia Maria Pătruţ, Mădălina Șteţca, Radu Mircea Galasiu, Vlad Zolog, Adriana Zolog, Iacob Domşa, Ioan Șimon, Anca Mihailov, Olga Hilda Orăşan, Flaviu Mureşan
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引用次数: 0

Abstract

Although rare, subungual carcinoma is the most common malignant nail tumor. The symptomatology is not characteristic, being very similar to that of other nail and periungual diseases. For this reason, early diagnosis is usually established by performing a biopsy. With appropriate treatment, subungual carcinoma usually has a favorable prognosis. Metastatic cases are rarely encountered, but they usually have a poor therapeutic result. This article presents the case of a patient with subungual carcinoma (diagnosed by histopathological exam), initially treated by amputation of the distal and middle phalanges of the fourth finger. Two years after the operation, a recurrence in the epitrochlear nodes was diagnosed, for which epitrochlear lymphadenectomy and postoperative chemotherapy were performed. At 7 months, metastases were detected in the axillary nodes, which were treated with radiotherapy and chemotherapy. The appearance and development of the tumor at the elbow and the lower third of the arm led the patient to accept scapulohumeral disarticulation. The patient finally adapted to the physical infirmity, having a good general condition and an optimistic attitude.
甲下鳞状细胞癌导致手臂截肢
甲下癌虽罕见,但却是最常见的恶性指甲肿瘤。其症状无特征性,与其他指甲及口周疾病非常相似。由于这个原因,早期诊断通常是通过进行活检来确定的。经适当治疗,甲下癌通常有良好的预后。转移病例是罕见的,但他们通常有较差的治疗效果。这篇文章提出了一个病例的患者与甲下癌(通过组织病理学检查诊断),最初治疗截肢远端和中指骨的第四指。术后2年诊断为耳蜗上淋巴结复发,行耳蜗上淋巴结切除术及术后化疗。7个月时发现腋窝淋巴结转移,给予放疗和化疗。肿瘤在肘部和手臂下三分之一处的出现和发展导致患者接受肩胛骨肱骨分离术。患者最终适应了身体的虚弱,总体状况良好,态度乐观。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Mind and Medical Sciences
Journal of Mind and Medical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
61.10%
发文量
37
审稿时长
8 weeks
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