Byulleten Sibirskoy Meditsiny最新文献

{"title":"Электрокинетические свойства, растворение in vitro, потенциальная биосовместимость оксидных и оксинитридных пленок титана для сердечно-сосудистых стентов","authors":"I. A. Khlusov, V. Pichugin, A. A. Pustovalova, M. E. Konischev, A. N. Dzyuman, Matthias Epple, Mathias Ulbricht, E. Cicinskas, V. S. Gulaya, V. V. Vikhareva","doi":"10.20538/1682-0363-2015-2-55-66","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-2-55-66","url":null,"abstract":"A state of titanium oxide and oxynitride coatings on L316 steel has been studied before and after their contact with model biological fluids. Electrokinetic investigation in 1 mmol potassium chloride showed significant (more than 10 times) fall of magnitude of electrostatic potential of thin (200–300 nm) titanium films at pH changing in the range of 5–9 units during 2 h. Nevertheless, zeta-potential of all samples had negative charge under pH > 6.5. Long-term (5 weeks) contact of samples with simulated body fluid (SBF) promoted steel corrosion and titanium oxide and oxynitride films dissolution. On the other hand, sodium and chloride ions precipitation and sodium chloride crystals formation occurred on the samples. Of positive fact is an absence of calcification of tested artificial surfaces in conditions of long-term being in SBF solution. It is supposed decreasing hazard of fast thrombosis and loss of materials functional properties. According to in vitro experiment conducted, prospective biocompatibility of materials tested before and after their contact with SBF lines up following manner: Ti–O–N (1/3) > Ti–O–N (1/1), TiO2 > Steel. It may be explained by: 1) the corrosion-preventive properties of thin titanium oxide and oxynitride films; 2) a store of surface negative charge for Ti–O–N (1/3) film; 3) minor augmentation of mass and thickness of titanium films connected with speed of mineralization processes on the interface of solution/solid body. At the same time, initial (before SBF contact) differences of samples wettability became equal. Modifying effect of model biological fluids on physicochemical characteristics of materials tested (roughness enhancement, a reduction or reversion of surface negative potential, sharp augmentation of surface hydrofilicity) should took into account under titanium oxide and oxynitride films formation and a forecast of their optimal biological properties as the materials for cardiovascular stents.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OPTIMIZATION OF DIAGNOSTIC IMAGING IN BREAST CANCER","authors":"S. Velichko, Yury Tyukalov, I. Frolova, D. G. Bukharin, Ye. Ye. Bober","doi":"10.20538/1682-0363-2015-4-12-16","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-4-12-16","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CLINICAL AND SOCIAL RISK FACTORS OF TARDIVE DYSKINESIA IN PATIENTS WITH SCHIZOPHRENIA DURING ANTIPSYCHOTIC TREATMENT","authors":"Ye. G. Kornetova, A. Semke, Ye. G. Dmitrieva, Y. Borodyuk, A. Boyko","doi":"10.20538/1682-0363-2015-1-32-39","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-1-32-39","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTERNATIONAL ASPECTS OF EDUCATION AND TRAINING IN TELEMEDICINE","authors":"R. Engelbrecht, A. Hasman, J. Mantas, L. Nicholson","doi":"10.20538/1682-0363-2015-3-63-67","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-3-63-67","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE ROLE OF PROTEIN OXIDATIVE MODIFICATION IN REDOX-REGULATION OF CASPASE-3 ACTIVITY IN BLOOD LYMPHOCYTES DURING OXIDATIVE STRESS IN VITRO","authors":"O. L. Nosareva, Y. A. Stepovaya, N. Ryazantseva, Ye. V. Shakhristova, O. Vesnina, V. V. Novitsky","doi":"10.20538/1682-0363-2015-14-6-61-67","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-14-6-61-67","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE METHODS OF CHOLEDOCHOLITHIASIS TREATMENT","authors":"N. V. Merzlikin, V. F. Podgornov, Ye. V. Semichev, P. Bushlanov, V. D. Talacheva","doi":"10.20538/1682-0363-2015-4-99-109","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-4-99-109","url":null,"abstract":"The methods of choledocholithiasis treatment, which are currently used in clinics of the Russian Federation, has been presented. The problems of diagnosis and treatment of gallstones (GSD) in individuals of different age groups are spotlighted. In the study of treatment of cholelithiasis and choledocholithiasis, including arising complications, it can be concluded that so far the ideal method of treatment of this pa-thology has not been found. Up to now, the majority of doctor’s main treatment is surgical removal of gall stones by some method or other. This article also considers a conservative approach (drug: antispasmodics (selective and nonselective), and non-pharmacological: treatment, diet), describes the criteria and assessment of the effectiveness of therapeutic interventions that help in the question of further treatment: the continuation of drug therapy or assignment of surgical treatment. Invasive techniques that are covered in the article, namely, a tech-nique of remote and endoscopic lithotripsy, are high-tech and in demand at the moment, which, along with high efficiency removal of a stone, reduced the number and severity of postoperative complications. Additionally, in the analysis of the features of a particular method of treatment, advantages and disadvantages of different treatment methods are described, indications and contraindications (absolute and relative) together with complications, possible outcomes, and further prognosis are high-lighted .","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPACT OF A SINGLE AND CONTINUOUS AUDIOVISUAL STIMULATION ON HEART RATE VARIABILITY AND MECHANISMS OF AUTONOMIC REGULATION IN ATHLETES-CYCLICS","authors":"R. Aizman, M. Golovin","doi":"10.20538/1682-0363-2014-6-113-120","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-6-113-120","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2014-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"БИОМЕХАНИКА ФАЗЫ ПОЛЕТА ПРИ ВЫПОЛНЕНИИ ПРЫЖКА В ДЛИНУ С МЕСТА У СПОРТСМЕНОВ РАЗЛИЧНОЙ КВАЛИФИКАЦИИ","authors":"A. V. Razuvanova, Ye. V. Koshelskaya, V. I. Andreyev, I. V. Kapilevich","doi":"10.20538/1682-0363-2014-6-174-179","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-6-174-179","url":null,"abstract":"Biomechanical features of flight phase when running long jump from place of different qualification sportsmen were investigated by method of Motion Tracking. The obtained results showed that the effective control of body position during the phase of flight can improve the effectiveness of jump actions.. This control is performed by moving parts of the body – bending legs at the knee, extension in the hip joints, the joints of the spine, shoulder joints and, as a consequence, any additional torque, contributing to increase the range of the jumping. In untrained persons the effectiveness of the management body in flight is reduced due to weak coordination and a predominance of actions aimed at safe. All the patterns can be viewed as the result of formation of a particular movement pattern, based on the interaction of vestibular and statokinetic reflexes.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2014-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Пальмитиновая, олеиновая кислоты и их роль в патогенезе атеросклероза","authors":"V. N. Titov, A. M. Dygai, M. Y. Kotlovskiy, Ye. V. Kurdoyak, A. V. Yakimenko, I. Y. Yakimovich, N. Aksyutina, Y. V. Kotlovskiy","doi":"10.20538/1682-0363-2014-5-149-159","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-5-149-159","url":null,"abstract":"On the basis of phylogenetic theory of general pathology, the cause of a noninfectious disease whose occurrence in a population is more than 5–7% is an impaired biological function or reaction to the environment. From the general biology viewpoint, high mortality rate related to cardio-vascular diseases and atherosclerosis (intercellular deficiency of polyenic fatty acids (PFA)) is just extinction of the  Homo sapiens  population upon adaptation to new environmental factors. The biological function of throphology (feeding) and biological reaction of exotrophy (external feeding) are impaired in several aspects, the major of which is nonphysiologically high dietary content of saturated fatty acids, primarily, of palmitic fatty acid (FA). The lipoprotein system formed at early stages of phylogenesis cannot transport and provide physiological deposition of great amounts of palmitic FA, which leads to the development of an adaption (compensatory) and accumulation disease. This results in hypermipidemia, impaired bioavailability of PFA to cells, compesatory production of humoral mediators from ω-9 eicosatrienoic mead FA, disorders in physiological parameters of cell plasma membrane and integral proteins, nonphysiological conformation of apoВ-100 in lipoproteins, formation of ligandless lipoproteins (biological litter) and impairments in the biological function of endoecology, utilization of ligandless lipoproteins in arterial intima by phylogenetically early macrophages that do not hydrolyze polyenic cholesterol esters, increase in the intensity of the biological reaction of inflammation, and destructive and inflammatory lesions in arterial intima of an atheromatosis or atherothrombosis type. Atheromatous masses are catabolites of PFA which were not internalized by phylogenetically late cells via receptor-mediated pathway.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2014-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MOODLE – СИСТЕМА КОМПЬЮТЕРНОЙ ПОДДЕРЖКИ ДИСТАНТНОГО ОБУЧЕНИЯ","authors":"V. A. Tunda, E. A. Tunda","doi":"10.20538/1682-0363-2014-4-123-128","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-4-123-128","url":null,"abstract":"Moodle (Modular Object-Oriented Dynamic Learning Environment) is the system developed by the English-speaking community around the world for more than 10 years, supports both, offline and online training. In most cases, Moodle is used to support and connect learning face-to-face with online training, as well as with other types of learning. Moodle allows you to ask all sorts of questions and assess responses in a variety of ways. The central concept of Moodle is a course in which one or more teachers offer students resources (such as files, folders, Web pages) and participate in interactive activities (such as forums, wikis, blogging, lessons, seminars, assignments, examinations). Students and teachers can change roles, mutually assess each other, share knowledge on the topics of study in the glossary and database system. In the English-speaking world, there are public sites with detailed documentation on Moodle, which is constantly verified and modified in accordance with emerging new versions of the system; Russian versions do not have public sites with detailed translation of the English-language documentation. On what and to whom you want to perform actions in the daily practice of the modern versions, only the barest of outlines on paid seminars and presentations to those who started the implementation of Moodle in your organization are given. And this despite the fact that the system has a great variety of Moodle (over 500) settings with different levels of functionality to be performed, to maintain and develop specially organized by the team of specialists. The question is not only about creating a training course in Moodle. It's about maintaining the health of the system within the institution, such as a University. Under the \"health maintenance\" means: availability and preservation of up-to-date documentation on system and manuals on Moodle separately for administrators, managers, teachers and students at their level, training consultants for each level and help Moodle users to carry out their work in an ever-growing versions of this system. The second important feature of the group is to perform administrative work on authentication of users and transfer/expulsion from the course assignment and modification of the roles, responsibilities and opportunities of users of Moodle, backing up, and take the necessary measures to ensure the confidentiality and security, implement the necessary measures for transfer students with the course on the course, at the end of the semester or school year, maintaining the required accounting and reporting documents, and so on. This article tries to understand the enormous potential of Moodle in transposition on the duties of the officers of the ad hoc group support this system within the University as a whole. Only competent and timely response to the needs of the teachers involved in the conduct of training courses in Moodle environment can allow to achieve a high level of educational services.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2014-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}