Revista Colombiana de Quimica最新文献_第2页

Acoplamiento molecular y modelado tridimensional por homología de flavonoides derivados de amentoflavona con las neuraminidasas H1N1 y H5N1 del virus de gripe aviar 门冬黄酮衍生物类黄酮与禽流感病毒H1N1和H5N1神经氨酸酶的分子对接和三维同源性建模

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Revista Colombiana de Quimica Pub Date : 2022-06-29 DOI: 10.15446/rev.colomb.quim.v50n3.97430

Ricardo Vivas Reyes, Alejandro Morales, Johana Márquez Lázaro, Roger Varela, Leandro Herrera, Catalina Vivas Gómez

{"title":"Acoplamiento molecular y modelado tridimensional por homología de flavonoides derivados de amentoflavona con las neuraminidasas H1N1 y H5N1 del virus de gripe aviar","authors":"Ricardo Vivas Reyes, Alejandro Morales, Johana Márquez Lázaro, Roger Varela, Leandro Herrera, Catalina Vivas Gómez","doi":"10.15446/rev.colomb.quim.v50n3.97430","DOIUrl":"https://doi.org/10.15446/rev.colomb.quim.v50n3.97430","url":null,"abstract":"El virus de la influenza A es el responsable de la gripe aviar, condición patológica que afecta principalmente aves, caballos y mamíferos marinos, sin embargo, el subtipo H5N1 tiene la capacidad de infectar a los humanos de forma rápida, exponiéndolos a un posible evento pandémico. Por tanto, el objetivo de este estudio fue realizar el acoplamiento molecular y modelado tridimensional por homología de flavonoides derivados de amentoflavona con las neuraminidasas H1N1 y H5N1 del virus de gripe aviar. Inicialmente, se obtuvo por homología la estructura 3D de la neuraminidasa H1N1. Seguido, se realizó un acoplamiento molecular de H1N1 con seis ligandos (F36, Ginkgetin, 3S,3R, 5S,5R, 6S y 6R), y más adelante H5N1 y los ligandos F36, Ginkgetin, 5R y 6R. Finalmente, a los complejos obtenidos se les realizó un análisis de interacciones. Los resultados dejaron en evidencia una relación entre la actividad inhibitoria y las interacciones tipo puente de hidrógeno e hidrofóbicas formadas entre el sitio activo de las neuraminidasas y los ligandos. Además, se observó una mejora en la actividad inhibitoria de los ligandos para la estereoquímica tipo R y sustituyentes poco voluminosos. De ahí que se propongan la evaluación experimental de los ligandos 5R y 6R como potenciales inhibidores de H5N1.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42183617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoprotective action, antioxidant activity, and toxicity of aqueous extracts of Campomanesia sessiliflora O. Berg 水提物的光保护作用、抗氧化活性和毒性

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Revista Colombiana de Quimica Pub Date : 2022-06-29 DOI: 10.15446/rev.colomb.quim.v50n3.97095

Thiago Luis Aguayo de Castro, Bianca Duarte Ferreira, C. Cardoso

引用次数: 3

Síntesis del hidróxido de níquel (II) con disolución multicomponente de la lixiviación de sulfuro de la tecnología Caron 卡隆硫化浸出技术多组分溶解合成氢氧化镍（II）

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Revista Colombiana de Quimica Pub Date : 2021-08-25 DOI: 10.15446/rev.colomb.quim.v50n2.89644

Deisy Cisneros-Sánchez, Alexis Otero-Calvi, Omaida Quesada-González, Mercedes Sosa-Martínez, Neicis Capote-Flores

{"title":"Síntesis del hidróxido de níquel (II) con disolución multicomponente de la lixiviación de sulfuro de la tecnología Caron","authors":"Deisy Cisneros-Sánchez, Alexis Otero-Calvi, Omaida Quesada-González, Mercedes Sosa-Martínez, Neicis Capote-Flores","doi":"10.15446/rev.colomb.quim.v50n2.89644","DOIUrl":"https://doi.org/10.15446/rev.colomb.quim.v50n2.89644","url":null,"abstract":"Se determinaron las condiciones más favorables para la síntesis de hidróxido de níquel (II) por precipitación química a partir de la disolución lixiviada del sulfuro de níquel de la tecnología Caron. La disolución lixiviada de fuerza iónica igual a 4,6 mol·L–1 fue tratada con hidróxidos de amonio y sodio. Se calcularon las propiedades termodinámicas como entalpía, entropía y energía libre y se construyeron diagramas de zona de predominancia. Se demostró la conveniencia de realizar el proceso a 303 K, pH entre 11 y 13 y concentración de amoníaco de 0,5 a 1,0 mol·L-1. En estas condiciones fueron obtenidas altas eficiencias de precipitación de los cationes metálicos de la disolución inicial. El sólido precipitado se caracterizó mediante espectrometría de absorción atómica y difracción de rayos X. Se obtuvo un beta-hidróxido de níquel (II) con la siguiente composición química: 58,5 ≤ Ni ≤ 59,1%, 1,7 ≤ Co ≤ 2,1%, 0,5 ≤ Fe ≤ 0,6%, Cu, Zn, Mn y Mg ≤ 0,2%.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44454999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A dual perspective (conventional and solar-enhanced) on advanced oxidation processes for the treatment of Agave cocui vinasses 龙舌兰果醋高级氧化工艺的双重视角（传统和太阳能强化）

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Revista Colombiana de Quimica Pub Date : 2021-08-25 DOI: 10.15446/rev.colomb.quim.v50n2.93101

J. Ferrer-Gutiérrez, Jovanny Angelina Santos-Luna, Jhonny Edgar Pérez-Rodríguez, J. Marcheno-Revilla, F. Cuenca-Mayorga

{"title":"A dual perspective (conventional and solar-enhanced) on advanced oxidation processes for the treatment of Agave cocui vinasses","authors":"J. Ferrer-Gutiérrez, Jovanny Angelina Santos-Luna, Jhonny Edgar Pérez-Rodríguez, J. Marcheno-Revilla, F. Cuenca-Mayorga","doi":"10.15446/rev.colomb.quim.v50n2.93101","DOIUrl":"https://doi.org/10.15446/rev.colomb.quim.v50n2.93101","url":null,"abstract":"Agave cocui vinasse was physicochemically characterized with reference to the relevant environmental regulations. The following results were obtained: COD: 71,000 mg.L-1, total solids: 21,000 mg.L-1, dissolved solids: 17,000 mg.L-1; pH: 4.06, conductivity: 9.45 mhoscm-1, total Fe: 48.83 mg.L-1, total phenols: 8.66 mg.L-1; BOD: 30,000 mg.L-1. Fenton and photo-Fenton reactions were applied to treat the wastewater produced. For the Fenton process, the optimal oxidation conditions found were pH = 3.48, [COD]:[H2O2] mass ratio = 1:5, and [Fe+2]: [H2O2] mass ratio = 1:6. For the photo-Fenton process, the optimal parameters found were: pH = 3.98, [COD]:[H2O2] = 1:7.86, and [Fe+2]: [H2O2] = 1:5. The experimental data were adjusted to fit second order polynomial models with R2 = 0.88 for the Fenton process and R2 = 0.91 for the photo-Fenton process, respectively. The sludge produced featured the following characteristics: average COD: 41,000 mg.L-1, total Fe: 296,000 mg.L-1, pH: 7.7. The variables with the greatest influence in both processes were [Fe+2]:[H2O2] and [COD]:[H2O2].","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47080258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identificación de una triparedoxina peroxidasa citoplasmática en Leishmania braziliensis 巴西利什曼原虫细胞质三氧化二氮过氧化物酶的鉴定

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Revista Colombiana de Quimica Pub Date : 2021-08-25 DOI: 10.15446/rev.colomb.quim.v50n2.91721

Sharon Eliana Villamil-Silva, Lesly Johanna Ortiz-Joya, Luis Ernesto Contreras-Rodríguez, Gonzalo Jair Díaz- Gonzalez, María Helena Ramírez-Hernández

{"title":"Identificación de una triparedoxina peroxidasa citoplasmática en Leishmania braziliensis","authors":"Sharon Eliana Villamil-Silva, Lesly Johanna Ortiz-Joya, Luis Ernesto Contreras-Rodríguez, Gonzalo Jair Díaz- Gonzalez, María Helena Ramírez-Hernández","doi":"10.15446/rev.colomb.quim.v50n2.91721","DOIUrl":"https://doi.org/10.15446/rev.colomb.quim.v50n2.91721","url":null,"abstract":"Los sistemas de defensa anti-oxidante utilizados por el parásito intracelular Leishmania braziliensis durante el proceso de infección permiten eliminar especies reactivas de oxígeno y nitrógeno a expensas de equivalentes reductores derivados de la tripanotiona, evitando daños celulares del patógeno. Con el objetivo de identificar potenciales blancos moleculares para el desarrollo de fármacos contra este parásito, se realizó la detección de la enzima triparedoxina peroxidasa citoplasmática de L. braziliensis (LbTXNPxII), la cual es esencial para disminuir concentraciones tóxicas de peróxido de hidrógeno en el contexto de infección. Para esto se generaron anticuerpos policlonales en modelo aviar, partiendo de la clonación, expresión y purificación de la proteína recombinante 6xHis-SUMO-LbTXNPxII (37kDa) en el sistema heterólogo Escherichia coli. La proteína purificada se utilizó como antígeno para la producción de anticuerpos IgY, cuya implementación en estudios in situ permitió detectar y localizar la enzima LbTXNPxII endógena (22kDa) en el citoplasma de promastigotes fijados y verificar su interacción molecular con la nicotinamida/nicotinato mononucleótido adenilil transferasa, enzima involucrada en la síntesis del NAD. De este modo, se reporta el desarrollo de una herramienta bioquímica para la identificación y estudio de la enzima LbTXNPxII y su participación en vías del metabolismo energético y de defensa anti-oxidante.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48209126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Estudio estructural y supramolecular del ácido 2-E-((4-hidroxifenil) diazenil) benzoico 2-E-（（4-羟基苯基）二氮杂）苯甲酸的结构和超分子研究

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Revista Colombiana de Quimica Pub Date : 2021-08-25 DOI: 10.15446/rev.colomb.quim.v50n2.90173

Richard F. D’Vries, Camila A. García-Carreño, Camila Cardona-Restrepo, Elizabeth Castro-Giraldo, Oscar E. Rojas-Alvarez, Javier Ellena

{"title":"Estudio estructural y supramolecular del ácido 2-E-((4-hidroxifenil) diazenil) benzoico","authors":"Richard F. D’Vries, Camila A. García-Carreño, Camila Cardona-Restrepo, Elizabeth Castro-Giraldo, Oscar E. Rojas-Alvarez, Javier Ellena","doi":"10.15446/rev.colomb.quim.v50n2.90173","DOIUrl":"https://doi.org/10.15446/rev.colomb.quim.v50n2.90173","url":null,"abstract":"La estructura cristalina del compuesto ácido 2-E-((4-hidroxifenil) diazenil) benzóico se resolvió por medio del método de fase intrínseca usando datos de difracción de rayos X de monocristal, encontrando que la molécula cristaliza en el sistema cristalino ortorrómbico con grupo espacial Pbca. Dentro de su celda unidad hay cuatro moléculas por unidad asimétrica que son confórmeros moleculares. Estos confórmeros forman hélices beta a lo largo de la dirección [010]. A partir de los datos estructurales se realizó el cálculo de superficies de Hirshfeld determinando, a partir de ellas, sus correspondientes diagramas de huellas dactilares bidimensionales, lo que permitió estudiar las interacciones intermoleculares que más contribuyen al empaquetamiento cristalino. Así, se pudo determinar que la principal contribución a la superficie general está dada por los contactos H···H (34,8%), seguida de interacciones O···H/H···O (27%) y C···H/H···C (18,6%). También fueron calculadas las redes energéticas de interacción con un nivel de teoría DFT/B3LYP/6-31G(d,p), permitiendo cuantificar los valores de cada componente que aportan a la energía total, siendo las interacciones de dispersión (-57,5 kJ/mol) las que más contribuyen en la formación del empaquetamiento cristalino para este compuesto.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45270033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ácido L-poliláctico (PLA) y nanotubos de carbono de pared múltiple (NTCPM) con potenciales aplicaciones industriales 聚乳酸（PLA）和多壁碳纳米管（NTCPM）具有潜在的工业应用

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Revista Colombiana de Quimica Pub Date : 2021-03-25 DOI: 10.15446/REV.COLOMB.QUIM.V50N1.89838

Jose-Roberto Vega-Baudrit, Fabian Murillo Vargas, Guillermo Jiménez Villalta, Marianelly Esquivel Alfaro

{"title":"Ácido L-poliláctico (PLA) y nanotubos de carbono de pared múltiple (NTCPM) con potenciales aplicaciones industriales","authors":"Jose-Roberto Vega-Baudrit, Fabian Murillo Vargas, Guillermo Jiménez Villalta, Marianelly Esquivel Alfaro","doi":"10.15446/REV.COLOMB.QUIM.V50N1.89838","DOIUrl":"https://doi.org/10.15446/REV.COLOMB.QUIM.V50N1.89838","url":null,"abstract":"The quality of some polymers to change their final physical and chemical properties by adding nanoparticles to the polymer matrix to produce a composite material (MC) is well known. This research is based on obtaining a MC from polylactic acid (PLA) and multi-walled carbon nanotubes (CNTMW), widely used in the packaging industry and biomedical devices, in order to expand its industrial profile.\u0000Four mixtures of PLA and CNTMW were developed, and polyethylene glycol (PEG) was used as a plasticizer. Their morphological, thermal, mechanical, thermo-mechanical, spectroscopic, contact angle, and crystallographic properties were evaluated. It was observed that the composites showed thermal degradation at temperatures below the matrix without CNTMW, as well as an increase in the modulus of flexion and tension in some of the samples. Likewise, it was observed that the CNTMW can increase the crystallinity of the material and that, in some cases, its rigidity is increased, acting as a useful additive for applications of greater mechanical stress than the matrix.\u0000From the effect of adding PEG in the composites, the CNTMW do not restrict the mobility of the polymer chains and a plasticizing effect occurs, which allows greater mobility of the amorphous zone of the polymer chains. In general terms, it was concluded that at higher CNTMW contents, better values were generated in the flexural modulus, maximum flexural stress, elongation modulus, maximum load stress and rupture stress, among other evaluated properties.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45572815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Regulación de la actividad enzimática de la NMNAT de Leishmania braziliensis por péptidos representativos de su extremo N-terminal 用代表巴西利什曼原虫N端的肽调节巴西利什曼原虫NMNAT的酶活性

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Revista Colombiana de Quimica Pub Date : 2021-03-25 DOI: 10.15446/REV.COLOMB.QUIM.V50N1.89863

Santiago Ávila-Jiménez, Luis Ernesto Contreras-Rodríguez, Carmen Giovana Granados-Ramírez, Z. J. Rivera-Monroy, María Helena Ramírez-Hernández

{"title":"Regulación de la actividad enzimática de la NMNAT de Leishmania braziliensis por péptidos representativos de su extremo N-terminal","authors":"Santiago Ávila-Jiménez, Luis Ernesto Contreras-Rodríguez, Carmen Giovana Granados-Ramírez, Z. J. Rivera-Monroy, María Helena Ramírez-Hernández","doi":"10.15446/REV.COLOMB.QUIM.V50N1.89863","DOIUrl":"https://doi.org/10.15446/REV.COLOMB.QUIM.V50N1.89863","url":null,"abstract":"The intracellular parasite Leishmania braziliensis is the etiological agent of cutaneous leishmaniasis, an endemic disease in the tropics, whose pharmacological treatments are toxic and for which there is currently no vaccine. For this reason, the study of proteins related to the energy metabolism of the parasite is relevant given its importance for its survival. In this study, based on the first 18 residues of the N-terminal end of the nicotinamide/nicotinate mononucleotide adenylyl transferase protein from L. braziliensis (Lb-NMNAT) as a template, peptides were synthesized implementing the Fmoc/tert-Butyl strategy in a Rink amide MBHA resin. The peptides were purified by C18 column chromatography and characterized by RP-HPLC. The recombinant 6xHisLb-NMNAT protein was expressed in Escherichia coli M15 cells and partially purified using immobilized metal affinity chromatography. The enzymatic activity of the protein was confirmed through direct enzymatic assays analyzed by RP-HPLC. The synthesized peptides were used to evaluate their effect on the enzymatic activity of the 6xHisLb-NMNAT protein, observing a differential modulation, which is promising for the design of chemotherapeutic tools based on the N-terminal sequence of the Lb-NMNAT protein.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47295697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microencapsulación mediante secado por atomización a partir de un extracto de los cálices de Hibiscus sabdariffa L. 从木槿花萼中提取的喷雾干燥微胶囊化。

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Revista Colombiana de Quimica Pub Date : 2021-03-25 DOI: 10.15446/REV.COLOMB.QUIM.V50N1.88424

Mercedes Campo Fernández, Donna Fiorella Granja Rizzo, Nubia Lisbeth Matute Castro, Osmany Cuesta Rubio, Ingrid Márquez Hernández

{"title":"Microencapsulación mediante secado por atomización a partir de un extracto de los cálices de Hibiscus sabdariffa L.","authors":"Mercedes Campo Fernández, Donna Fiorella Granja Rizzo, Nubia Lisbeth Matute Castro, Osmany Cuesta Rubio, Ingrid Márquez Hernández","doi":"10.15446/REV.COLOMB.QUIM.V50N1.88424","DOIUrl":"https://doi.org/10.15446/REV.COLOMB.QUIM.V50N1.88424","url":null,"abstract":"The objective of the research was to define the best conditions for ultrasound-assisted extraction of H. sabdariffa L. calyces, and to obtain microencapsulated powders, by spray drying. The extracts were analyzed, considering as variables: extracting solvent (water and water/ethanol) and the temperature /extraction time ratio (25 oC/60 min and 60 oC/30 min). Inlet air temperature (150 oC; 190 oC) and the mixture of gum arabic (G) and maltodextrin (MD) as encapsulating agents (G40/MD60; G60/MD40) were the variables studied. The parameters used for the analysis were: yield, pH, °Bx, chemical composition (phenols and total anthocyanins, HPLC-MS), and antioxidant capacity (DPPH). The best polyphenols extraction conditions were water:ethanol (80:20), at 60 °C for 30 min. The presence of phenolic acids, flavonol glycosides, and anthocyanins (delphinidin-3-sambubioside and cyanidin-3-sambubioside) were identified as the signals of highest intensity. Inlet air temperature at 150 °C and G60/MD40 allowed the highest total phenols and anthocyanins content. However, the antioxidant capacity was better at 150 °C and G40/MD60. The microparticle obtained could be used as an ingredient for the preparation of phytopharmaceuticals or functional foods, considering their easy handling, and antioxidant capacity.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45749374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of C60 and C70 acetylacetone monoadducts and study of their photochemical properties for potential application in solar cells C60和C70乙酰丙酮单加合物的合成、表征及其光化学性质的研究

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Revista Colombiana de Quimica Pub Date : 2021-03-25 DOI: 10.15446/REV.COLOMB.QUIM.V50N1.88545

Á. Duarte-Ruiz, H. Iuele, Sergio Alejandro Torres, A. Melendez, J. Velásquez, M. Chaur, A. Duarte-Ruiz, H. Iuele, S. A. Torres-Cortés, A. Melendez, J. Velásquez, M. N. Chaur

{"title":"Synthesis and characterization of C60 and C70 acetylacetone monoadducts and study of their photochemical properties for potential application in solar cells","authors":"Á. Duarte-Ruiz, H. Iuele, Sergio Alejandro Torres, A. Melendez, J. Velásquez, M. Chaur, A. Duarte-Ruiz, H. Iuele, S. A. Torres-Cortés, A. Melendez, J. Velásquez, M. N. Chaur","doi":"10.15446/REV.COLOMB.QUIM.V50N1.88545","DOIUrl":"https://doi.org/10.15446/REV.COLOMB.QUIM.V50N1.88545","url":null,"abstract":"We report on the synthesis of C60 and C70 monoadducts at room temperature through the Bingel reaction; employing acetylacetone as ligand; in presence of DBU (1,8-Diazabicyclo [5.4.0] undec-7-ene), carbon tetrabromide (CBr4), and o-dichlorobenzene. Diacetylmethane-[C60-Ih]-fullerene-[5,6] and diacetylmethane-[C70-D5h]-fullerene-[5,6] monoadducts were obtained with yields of 69% and 44%, respectively. The products were purified by column chromatography (CC, on silica gel, using hexane, carbon disulfide, and chloroform as eluents at room temperature) and characterized by Nuclear Magnetic Resonance (1H and 13C), Fourier-Transform Infrared (FT-IR) and UV-Visible spectroscopies, Matrix-assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) Mass spectrometry, Cyclic Voltammetry (CV), and Osteryoung Square Wave Voltammetry (OSWV). Both compounds showed irreversible reduction peaks controlled by diffusion, with LUMO energy levels of -3.09 eV, -3.13 eV for C60, and C70 monoadducts, respectively. These values are comparable with the -3.99 eV of PC61BM. The synthetized adducts were incorporated into inverted-type perovskite solar cells and were used as electron transporting materials (ETM) obtaining power conversion efficiencies (PCE) of 8.5% and 14.0% for the C60 and C70 monoadducts, respectively. When C60 is replaced by a lower symmetrical fullerene such as C70 an improved light absorption in the visible region is observed.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44208318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0