Kamil Nurczyk, Norbert Nowak, Tomasz Orczykowski, Dariusz Duma, Renata Gieroba, Grzegorz Wallner, Tomasz Skoczylas
{"title":"ApoA-I and ApoB levels, and ApoB-to-ApoA-I ratio as candidate pre-treatment biomarkers of pathomorphological response to neoadjuvant therapy in gastric and esophago-gastric junction adenocarcinoma","authors":"Kamil Nurczyk, Norbert Nowak, Tomasz Orczykowski, Dariusz Duma, Renata Gieroba, Grzegorz Wallner, Tomasz Skoczylas","doi":"10.5604/01.3001.0053.8925","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8925","url":null,"abstract":"Background: Neoadjuvant chemotherapy (NAC) is a part of the current standard of care in a locally advanced gastric adenocarcinoma (GA) and esophago-gastric junction adenocarcinoma (EGJA), but only patients with good pathomorphological response (pR) to NAC benefit from prolonged overall survival. The study aims to evaluate ApoA-I and ApoB as candidate pre-treatment biomarkers of pR to NAC in patients with GA and EGJA.Method: Serum samples were collected from 18 patients with GA and 9 with EGJA before the initiation of NAC to determine the ApoA-I and ApoB levels. After NAC tumor regression grade (TRG) was evaluated in resected specimens according to Mandard’s tumor regression grading system and correlated with pre-treatment ApoA-I and ApoB serum concentration, and ApoB-to-ApoA-I serum concentration ratio.Results: We found a positive correlation of ApoA-I level and pR (95% CI: -0.863 to -0.467; p < 0.0001), a negative correlation of ApoB level and pR (95% CI: 0.445 to 0.857; p < 0.0001), a negative correlation of ApoB-to-ApoA-I ratio and pR (95% CI: 0.835 to 0.964; p < 0.0001).Conclusions: ApoA-I and ApoB levels, and ApoB-to-ApoA-I ratio are candidate pre-treatment predictors of pR to NAC in GA and may help to guide personalized therapy.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"166 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136378999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomasz Banasiewicz, Waldemar Machała, Maciej Borejsza Wysocki, Maciej Lesiak, Sebastian Krych, Małgorzata Lange, Piotr Hogendorf, Adam Durczyński, Jarosław Cwaliński, Tomasz Bartkowiak, Adam Dziki, Wojciech Kielan, Stanisław Kłęk, Łukasz Krokowicz, Krzysztof Kusza, Piotr Myśliwiec, Michał Pędziwiatr, Piotr Richter, Jacek Sobocki, Marek Szczepkowski, Wiesław Tarnowski, Wojciech Zegarski, Michał Zembala, Krzysztof Zieniewicz, Grzegorz Wallner
{"title":"Principles of minimize bleeding and the transfusion of blood and its components in operated patients – surgical aspects","authors":"Tomasz Banasiewicz, Waldemar Machała, Maciej Borejsza Wysocki, Maciej Lesiak, Sebastian Krych, Małgorzata Lange, Piotr Hogendorf, Adam Durczyński, Jarosław Cwaliński, Tomasz Bartkowiak, Adam Dziki, Wojciech Kielan, Stanisław Kłęk, Łukasz Krokowicz, Krzysztof Kusza, Piotr Myśliwiec, Michał Pędziwiatr, Piotr Richter, Jacek Sobocki, Marek Szczepkowski, Wiesław Tarnowski, Wojciech Zegarski, Michał Zembala, Krzysztof Zieniewicz, Grzegorz Wallner","doi":"10.5604/01.3001.0053.8966","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8966","url":null,"abstract":"One of the target of perioperative tratment in surgery is decreasing intraoperative bleeding, which increases the number of perioperative procedures, mortality and treatment costs, and also causes the risk of transfusion of blood and its components. Trying to minimize the blood loss(mainly during the operation) as well as the need to transfuse blood and its components (broadly understood perioperative period) should be standard treatment for a patient undergoing a procedure. In the case of this method, the following steps should be taken: 1) in the preoperative period: identyfication of risk groups as quickly as possible, detecting and treating anemia, applying prehabilitation, modyfying anticoagulant treatment, considering donating one's own blood in some patients and in selected cases erythropoietin preparations; 2) in the perioperative period: aim for normothermia, normovolemia and normoglycemia, use of surgical methods that reduce bleeding, such as minimally invasive surgery, high-energy coagulation, local hemostatics, prevention of surgical site infection, proper transfusion of blood and its components if it occurs; 3) in the postoperative period: monitor the condition of patients, primarily for the detection of bleeding, rapid reoperation if required, suplementation (oral administration preferred) nutrition with microelements (iron) and vitamins, updating its general condition. All these activities, comprehensively and in surgical cooperation with the anesthesiologist, should reduce the blood loss and transfusion of blood and its components.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136375666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomasz Banasiewicz, Jarosław Kobiela, Jarosław Cwaliński, Piotr Spychalski, Patrycja Przybylska, Karolina Kornacka, Dagmara Bogdanowska-Charkiewicz, Magdalena Leyk-Kolańczak, Maciej Borejsza-Wysocki, Dominika Batycka-Stachnik, Rafał Drwiła
{"title":"Recommendations on the use of prehabilitation, i.e. comprehensive preparation of the patient for surgery","authors":"Tomasz Banasiewicz, Jarosław Kobiela, Jarosław Cwaliński, Piotr Spychalski, Patrycja Przybylska, Karolina Kornacka, Dagmara Bogdanowska-Charkiewicz, Magdalena Leyk-Kolańczak, Maciej Borejsza-Wysocki, Dominika Batycka-Stachnik, Rafał Drwiła","doi":"10.5604/01.3001.0053.8854","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8854","url":null,"abstract":"Prehabilitation is a comprehensive preparation of a patient for primarily surgical treatments. Its aim is to improve the patient'sgeneral condition so as to reduce the risk of complications and ensure the fastest possible recovery to full health. Thebasic components of prehabilitation include: improvement of nutritional status, appropriate exercises to improve functioning,psychological support, and help in eliminating addictions. Other important aspects of prehabilitation are: increasinghemoglobin levels in patients with anemia, achieving good glycemic control in patients with diabetes, treatment or stabilizationof any concurrent disorders, or specialist treatment associated with a specific procedure (endoprostheses, ostomyprocedure). This article organizes and outlines the indications for prehabilitation, its scope, duration, and the method to conductit. Experts of various specialties related to prehabilitation agree that it should be an element of surgery preparationwhenever possible, especially in patients with co-existing medical conditions who have been qualified for major procedures.Prehabilitation should be carried out by interdisciplinary teams, including family physicians and various specialists in thetreatment of comorbidities. Prehabilitation requires urgent systemic and reimbursement solutions.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"207 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Iljin, Bogusław Antoszewski, Tomasz Szewczyk, Aneta Sitek
{"title":"Selected factors affecting the rate of reduction of body weight components during the first six months after bariatric surgery: cohort study","authors":"Aleksandra Iljin, Bogusław Antoszewski, Tomasz Szewczyk, Aneta Sitek","doi":"10.5604/01.3001.0053.8609","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8609","url":null,"abstract":"Purpose: To determine whether the rate of slimming following bariatric surgery depends on the sex, type of bariatric surgery, time elapsed from surgery and body weight components.Materials and methods: The material comprises the results of three series of anthropometric measurements in 91 obese patients (before bariatric surgery, after about 3 months and after about 6 months from bariatric surgery). Inclusion criteria: all patients of Polish origin who were admitted to hospital from July 1, 2017 to January 31, 2019 for the purpose of surgical treatment of obesity, and who expressed written consent for surgery and participation in the study. Measurements included: body weight components assessed by electric bioimpedance metod. Results: Reduction of all features was higher after SG than GB (p<0.0001), higher in the first quartile than in the secondo quartile after surgery (p<0.0001) and higher for fat mass than for other components of body weight (p<0.0001). Sex of patients, type of bariatric surgery, time elapsed from operation and type of body weight component constitute interactive modifiers of the reduction rate.Conclusion: After bariatric surgery the reduction of fat mass is quicker in men than in women. SG and RYGB lead to higher reduction of fat mass GB. Only after SG among all three analyzed operative procedures the rate of body weight components reduction does not decrease in the second quartile after surgery. The above information should be taken into account when creating an algorithm for handling a patient after bariatric surgery.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135487029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sajad Ahmad Salati, Lamees Sulaiman Alsulaim, Mohammed Ahmed Elmuttalut, Mohammed Alfehaid, Saleh Ahmad Alsuwaydani
{"title":"Tumoral pseudoangiomatous stromal hyperplasia (PASH) of the male breast: a systematic analysis.","authors":"Sajad Ahmad Salati, Lamees Sulaiman Alsulaim, Mohammed Ahmed Elmuttalut, Mohammed Alfehaid, Saleh Ahmad Alsuwaydani","doi":"10.5604/01.3001.0053.8610","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8610","url":null,"abstract":"ABSTRACTAim: The study was conducted to systematically analyze the recent peer-reviewed literature related to tumoral pseudoangiomatous stromal hyperplasia (PASH) in males. Materials and methods: Articles published in peer-reviewed journals of repute from 2012–2023 were evaluated for eight variables, including: [i] age of the patient; [ii] clinical presentation; [iii] laterality (unilateral or bilateral); [iv] associated breast disorder; [v] systemic co-morbidity if any; [vi] imaging modalities that helped in diagnosis; [vii] treatment; and [viii] recurrence.Results: There were 10 cases ranging in age from 1 year to 67 years (mean 34.5 years). 8 cases (80%) had breast lumps, and 2 cases (20%) had axillary lumps at presentation. Pain was not a prominent symptom. Six cases (60%) had another breast disorder at presentation, and three cases (30%) had significant systemic co-morbidities, including diabetes and renal insufficiency. The greatest dimension of the lumps ranged from 2 cm to 12 cm, with 80% of the lumps being below 5 cm in size. Imaging modalities utilized in evaluation included breast ultrasound (USG), mammograms, computerized tomography (CT), and magnetic resonance imaging (MRI). All the cases were treated surgically, and the final diagnosis was made only after the analysis of the surgical specimen. Recurrence was recorded in two (20%) cases.Conclusion: Tumoral PASH is a benign myofibroblastic proliferation disorder rarely reported in males. This condition should be considered a differential diagnosis of breast or axillary lumps, and evaluation accordingly should be initiated. The recommended course of treatment is adequate surgical excision with regular clinical and radiological follow-up.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Pietrzak, G. Rydzewska, K. Neubauer, T. Banasiewicz, W. Tarnowski
{"title":"One-year cyclic therapy with rifaximin-α is effective in the treatment of SUDD (Symptomatic Uncomplicated Diverticular Disease) also in patients with a history of complicated diverticulitis","authors":"A. Pietrzak, G. Rydzewska, K. Neubauer, T. Banasiewicz, W. Tarnowski","doi":"10.5604/01.3001.0053.8079","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8079","url":null,"abstract":"Introduction: The treatment of diverticulosis symptoms in patients with a history of diverticulitis is a challenge in everyday clinical practice. Aim: Efficacy assessment of a cyclic, year-long treatment with rifaximin-α in patients with symptomatic uncomplicated diverticular disease (SUDD) and a history of past diverticulitis. Material and methods: This study is a multicenter, retrospective, observational study involving 48 centers. The study group included patients who reported to the outpatient clinic within a month with SUDD symptoms, who had a history of diverticulitis, and who were given a cyclic rifaximin-α treatment of 2 x 400 mg/day for 7 days and then once a month for 12 months. Epidemiological and demographic data, the course of diverticulosis, the number of inflammation episodes and their diagnoses, complications, symptoms of SUDD, and its treatment were evaluated. The efficacy of rifaximin-α therapy was assessed on a 4-point scale (0 – no symptoms, 3 – severe symptoms) every 3 months, and analyzed: pain, tenderness, bloating, bowel movements, and recurrence of inflammation during the 12-month treatment. Results: 178 patients (67% women, median age 65 years [34–92]) were included in the study. The average duration of diverticulosis was 6.4 years (3–20), and 59% of patients had more than one episode of diverticulitis during this period. In total, 87% of patients had symptoms of SUDD after or between episodes of diverticulitis. Abdominal pain was the most common symptom (92%). An inflammation episode was diagnosed using imaging in 50.5% of cases, and the rest – based on typical clinical symptoms. As many as 46.2% of patients required hospitalization, and complications were diagnosed in 44% of cases. One hundred and seventy (95%) patients completed the 12-month rifaximin-α therapy. Changes in the severity of pain, abdominal tenderness, diarrhea, constipation, and bloating were assessed every 3 months. After 12 months of treatment with rifaximin-α, there was a statistically significant reduction in the severity of symptoms overall (median from 1.5 [0–3 points] to 0.2; P<0.001) and each symptom evaluated individually. Regardless of the previous diagnostic method of diverticulitis (imaging or typical clinical presentation) or its complications (e.g. perforation, abscess), treatment with rifaximin-α was equally effective. Conclusions: Cyclic therapy with rifaximin-α is effective in treating SUDD symptoms and in preventing the recurrence of symptoms, also in patients with a history of diverticulitis – regardless of how the diagnosis was made and disease complications. The extended treatment regimen leads to a gradual resolution of symptoms during 12 months of observation. Cyclic use of rifaximin-α is necessary to maintain symptom remission.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49243710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Zangouri, Negin Nourinejad, Souzan Soufizadeh Balaneji, Ali Ghaeini Hesarooeih, Seyed Amin Mousavi, Aliey Ranjbar, Morteza Amestejani, M. Ghoddusi Johari, M. Shariat, Maral Mokhtari
{"title":"Comparison of clinicopathologic characteristics of Invasive Papillary Carcinoma with Invasive Ductal Carcinoma and their survival outcome","authors":"V. Zangouri, Negin Nourinejad, Souzan Soufizadeh Balaneji, Ali Ghaeini Hesarooeih, Seyed Amin Mousavi, Aliey Ranjbar, Morteza Amestejani, M. Ghoddusi Johari, M. Shariat, Maral Mokhtari","doi":"10.5604/01.3001.0053.7691","DOIUrl":"https://doi.org/10.5604/01.3001.0053.7691","url":null,"abstract":"Background: Invasive Papillary Carcinoma (IPC) of the breast is a rare breast cancer subtype. This study aimed to evaluate the clinicopathologic characteristics of IPC of the breast, its differences from Invasive Ductal Carcinoma (IDC), and their survival outcomes.Materials and Methods: The medical records of 6599 patients were retrospectively reviewed at the Breast Disease Research Center from December 1993 to December 2021. The patients were divided into two groups: IPC and IDC. The tumor size, lymph node metastasis, pathologic stage, nuclear and histological grade, hormonal receptor status, and survival were reviewed and compared between the IPC and IDC groups.Results: Of the 6599 patients, 27 had IPC, and 6572 had IDC. The mean age of patients with IPC and IDC was 58.5 and 49 years, respectively (P=0.02). Patients with IPC were more likely to have a positive node status and had a significantly higher incidence of lymphovascular invasion (14.9% for IPCs and 53.3% for IDCs, P<0.001). ER status was positive in 66.6% of IPCs and 78.1% of IDCs (P=0.23). Additionally, 62.5% of patients with IPC and 94.9% of those with IDC received adjuvant chemotherapy (P<0.001). Disease-free survival (DFS) and overall survival (OS) were better in IPC patients for stage I (5-year DFS: 69% vs. 81%, P=0.008; 5-year OS: 75% vs. 85%, P=0.001).Conclusion: IPC is a rare tumor type that presents unique clinicopathological characteristics and is associated with a higher rate of breast-conserving surgery and a favorable prognosis than IDC","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"46 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Ejtehadi, Ali Reza Taghavi, Farshid Ejtehadi, I. Shahramian, R. Niknam, Maryam Moini, Masoud Tahani
{"title":"Prevalence of Colonic Polyps Detected by Colonoscopy in Symptomatic Patients and Comparison Between Different Age Groups. What Should Age be Considered for Investigation?","authors":"F. Ejtehadi, Ali Reza Taghavi, Farshid Ejtehadi, I. Shahramian, R. Niknam, Maryam Moini, Masoud Tahani","doi":"10.5604/01.3001.0053.3997","DOIUrl":"https://doi.org/10.5604/01.3001.0053.3997","url":null,"abstract":"Introduction: The Burden of Colorectal cancer (CRC) as one of the most common malignancies is considerable worldwide, with 1.8 million diagnoses each year. Although it is well established that most CRCs arise from colonic polyps, guidelines and recommendations indicate different ages as starting points for endoscopic examination of the colon, either as cancer screening programs or in symptomatic patients. Most standard guidelines adapt the cut-off age of 50. However, this has been challenged by the results of recent studies. This multicentric prospective study aimed to investigate the frequency, distribution, and histopathological findings of colonic polyps in patients who underwent colonoscopy with special attention to the age group of 40–49-year-olds compared with 50–59 in the population. Material and methods: This multicentric, prospective study was designed to enroll adult patients referred to three universityaffiliated endoscopy units. As many as 723 patients met all the inclusion criteria. Data analysis was performed on endoscopic and histopathological characteristics of all detected lesions, including colonic polyps and neoplastic lesions. Results: A total of 723 patients with a mean age of 46.03 (16.8) years were included in this study. Rectal bleeding was the most frequent symptom (40.9%). One hundred and thirteen patients (15.6%) were found to have colonic polyps, and 11 cases (1.52%) of CRC were detected. Most polyps were located in the left colon (67.5%). There was no statistical difference in the prevalence of adenomatous polyps between the age group of 40–49 years and 50–59 years (P = 0.77). Detailed examination of data using receiver operating characteristic (ROC) curve analysis not only showed age is a risk factor for the presence of colonic polyps but also revealed the cut-off age of 42.5 for the presence of all types of colonic polyps (44.5 years for adenomatous polyps). Conclusion: This study has showed a similar polyp prevalence in the age group of 40-49 years as compared to 50-59. Our study suggests that appropriate colon examination should be performed at a younger age to achieve early detection of colonic polyps, specifically in patients with red flag symptoms.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"370 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139360371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Principles for the use of non-steroidal anti-inflammatory drugs with proton pump inhibitors","authors":"A. Pietrzak","doi":"10.5604/01.3001.0053.7274","DOIUrl":"https://doi.org/10.5604/01.3001.0053.7274","url":null,"abstract":"Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in numerous areas of medicine. By inhibiting the prostaglandin synthesis pathway, they contribute to the development of injuries to the mucous membranes within the gastrointestinal tract, possibly leading to gastrointestinal bleeding. Proton pump inhibitors (PPIs) are used to prevent such events in high-risk groups. The bleeding risk is highest in patients above the age of 65, patients with a history of gastrointestinal bleeding, and patients with a history of peptic ulcer disease. The efficacy of bleeding prevention could not be proven in other groups. Notably, PPIs are associated with serious side effects, including acute kidney injury, malabsorption syndrome, and osteoporosis. Therefore, recommending the use of PPIs within the framework of prevention should be approached with caution. The widespread belief that IPP should be automatically prescribed together with NSAIDs is false and harmful to patients.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41667628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bartosz Wilczyński, Jan Śnieżyński, Małgorzata Nowakowska, Grzegorz Wallner
{"title":"Neurological complications in patients undergoing general surgery - a literature review","authors":"Bartosz Wilczyński, Jan Śnieżyński, Małgorzata Nowakowska, Grzegorz Wallner","doi":"10.5604/01.3001.0053.6869","DOIUrl":"https://doi.org/10.5604/01.3001.0053.6869","url":null,"abstract":"Surgical procedures are extremely burdensome for patients, as in addition to complications directly related to the intervention, they expose the patient to complications resulting from the disturbance of key functions for maintaining homeostasis of the body's systems, particularly the circulatory, respiratory, and nervous systems. Furthermore, they may contribute to the exacerbation of symptoms of chronic diseases present in the patient before surgical treatment. This paper focuses on the most common possible neurological complications that may occur after surgical procedures and includes topics such as stroke, chronic pain, neuropathy, and delirium. The risk factors for neurological deficits, their known or possible etiology, the most characteristic symptoms, and potential preventive actions are discussed. The paper analyzed articles from PubMed, ResearchGate, and Scopus databases. A surgeon's knowledge of possible complications that may occur in the perioperative period enables early recognition and effective reduction of their negative impact on the patient's functioning and quality of life after surgery, contributing to better overall treatment outcomes.","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136367704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}