International Journal of Health and Pharmaceutical (IJHP)最新文献

{"title":"Administration of Eucalyptus to Inhibit the Skin Aging Process of Rats (Rattus Norvegicus) Wistar Strains Exposed to Ultraviolet-B Light","authors":"Asira Mahrahmi, Tan Suyono, Ali Napiah Nasution","doi":"10.51601/ijhp.v4i2.340","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.340","url":null,"abstract":"Ageing weakens the skin's protective layer, causing pigmentation, inflammation, and cancer. Environmental hazards like pollution and UV radiation harm the skin. Antioxidants, like Eucalyptus globulus, protect against free radicals, making them valuable in medicinal use. The study aimed to investigate the efficacy of Eucalyptus administration in inhibiting skin ageing in rats exposed to ultraviolet-B light. A true experiment was conducted to examine the effectiveness of Eucalyptus in reducing skin ageing in Wistar rats exposed to ultraviolet-B radiation. The study used the \"3R Principle\" and SPSS to analyse the relationship between collagen quantity, Eucalyptus, and UVB radiation. The study found normal distribution for the control and treatment groups, with a significance of 0.200 and 0.091, respectively. The Levene test showed homogeneity and a T-test result 0.000, indicating a significant difference. The control group had a moderate collagen density, while the treatment group with Eucalyptus extract had a tighter collagen density. The study concludes that the Eucalyptus tree extracts, including tannins, saponins, and flavonoids, have been found to have anti-ageing and collagen-increasing effects in mice exposed to UVB light. The treatment group showed significantly increased collagen density, indicating potential anti-ageing properties in the treatment group.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"224 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141386875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Celery (Apium graveolens L.) Extract Administration on Kidney Function of White Rats (Rattus norvegicus) Wistar Strains Exposed to Lead","authors":"Shella Selviana Barus, Ali Napiah Nasution, Wienaldi Wienaldi","doi":"10.51601/ijhp.v4i3.339","DOIUrl":"https://doi.org/10.51601/ijhp.v4i3.339","url":null,"abstract":"Lead significantly affects health because of its sensitivity to the central nervous system and rapid absorption rate. The phytochemicals included in celery, such as flavonoids, may mitigate lead-induced kidney damage. This research aimed to determine how administering celery extract affected the expression of the Caspase-3 gene and the kidney TNF-α gene in Rattus Norvegicus Wistar white rats exposed to lead. The research method true experiment examined the effects of 80 mg/day celery extract on Caspase-3 gene expression and renal TNF-α gene expression in rats exposed to lead. Each of the three groups will include six rats; there will be eighteen male Wistar rats in the study. The study used SPSS 26.0 and the Saphiro Wills test to analyze data on TNF-α and Caspase 3 expression in rats exposed to lead acetate (Pb). The results showed a normal distribution for the negative control group (K-) and the positive control group (K+) and a normal distribution for the treatment group (P). However, the paired t-test showed significant differences in all treatment groups (p <0.05), indicating a normal distribution in the data. The study concludes the impact of celery extract on kidney function in lead-exposed Wistar rats, revealing various active compounds like flavonoids. Despite insignificant caspase 3 reduction, flavonoids showed potential in mitigating lead-induced kidney damage.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"208 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Covid-19 Vaccination And The Incidence Of Covid-19 At The Hospital Putri Hijau Hospital, Medan","authors":"Eva Sartika Dasopang, Desy Natalia Siahaan, Fenny Hasanah, Salmah Handayani Lubis, Yohana Yuni M, Ramona Pane","doi":"10.51601/ijhp.v4i2.338","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.338","url":null,"abstract":"Vaccination is the process of entering vaccines to stimulate the body's immune system, as a preventive effort in reducing morbidity and mortality caused by the coronavirus. Putri Hijau Hospital in Medan City, which participated in the second dose of Covid-19 vaccination, confirmed that the respondents who were still affected by Covid-19 needed to be developed, so in particular knowing the number of cases of Covid-19 that appeared in respondents who had been infected. received a second dose of vaccination. The purpose of this study was to see whether there was a relationship between vaccination and the incidence of Covid-19 at Putri Hijau Hospital in Medan.This type of research uses a quantitative approach method by using a questionnaire distributed through the Google Form platform on a smartphone to store all the answers that have been filled in by the respondent based on the questionnaire guidelines that have been made previously with the target of respondents who have vaccinated the second dose of Covid-19.The results showed that from 100 respondents there were 28 male patients (28%) and 72 female patients (72%). Judging from the age of most patients at the age of 15 to 25 years. There were 8 people and 92 people who were not exposed. With the symptoms of Covid-19, such as fever, cough, sore throat, and loss of sense of smell. This is because the respondents had antibodies that were formed slightly after vaccination, were active outside the home, did not apply health protocols and maintained their immune system so that they were exposed to Covid-19.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"78 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usage Of Government Formulary For BPJS Inpatients With Ischemic Stroke In Indonesia","authors":"Lukman Prayitno, Novita Novita, Sonya Esther, Erlina Puspitaloka Mahadewi","doi":"10.51601/ijhp.v4i3.347","DOIUrl":"https://doi.org/10.51601/ijhp.v4i3.347","url":null,"abstract":"Introduction: Ischemic stroke patients tend to use some medicine. In National Health Security (JKN), the government has created a government formulary as quality control and cost control. The study aims to determine the percentage of government formulary in Hospitals and the affected factors. Method: It was cross sectional quantitative research. It used retrospective data from medical record and prescription of ischemic stroke inpatients from January to June 2019. The data collected include hospital characteristics, patient characteristics, supporting characteristics and treatment costs. Result: The data cames from 17 hospitals. Based on the inclusion and exclusion criteria, 257 medical records were analyzed. The average percentage of drug use was 73.22%. Its was influenced by the hospital class, the number of supporting examinations, the number of drug items. Type B and C hospitals used non government formulary. There were citicolin, mecobalamin, piracetam, neurotropic multivitamin, flunarizine. Conclusion: The average percentage of drug use was still less than 100%. There were still non government formulary drugs used for the therapy of inpatient ischemic stroke. The use of non government formulary drugs was influenced by the hospital class, the number of supporting examinations, the number of drug items.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"40 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results from an Obesity Model in White Male Wistar Rats After Administration of Telang Flower (Clitoria Ternatea) Extract on Pancreatic Function and Histopathological Characteristics","authors":"Weni Yulisandra Rini, Fahrul Azmi Tanjung, Wilvia Wilvia","doi":"10.51601/ijhp.v4i2.323","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.323","url":null,"abstract":"Diabetes mellitus (DM) is a chronic disease affecting 95% of diabetics, characterized by high blood glucose levels due to decreased insulin production. Bioactive chemicals from plants like butterfly pea flower and Clitoria Ternatea can potentially treat DM, inhibit carbohydrate-digesting enzymes, and potentially regenerate pancreatic beta cells. This study tests butterfly pea flower extract on obesity-related pancreatic function in white rats. In obese rats given varied dosages of butterfly pea flower extract, the study evaluates pancreatic tissue histopathology and ethanol extract properties. The study examines male Wistar rats' acclimatization before treatment with butterfly pea flower extract, a high-fat diet, and butterfly pea flower extract, comparing the effects of the extract on rats. Pancreatic function is examined using enzymes amylase and lipase. Histopathological observation of pancreatic organs involves several steps, including fixation, washing, infiltration, embedding, cutting, attaching, deparaffinization, dealcoholization, staining, mounting, and scoring. A post-test-only control group design compared butterfly pea flower extract and pancreatic function in male white rats. Butterfly pea flower extract improved pancreatic histology in obese white rats at 600mg/KgWB, closer to the normal group. The extract contains secondary metabolites that repair cell tissue damaged by the rats' high-fat diet and obesity.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"1027 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140445755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison Of Buerger Allen Exercise With 3 Physical Therapy Modalities On The Value Of Ankle Brachial Index In Patients With Type Ii Diabetes Mellitus","authors":"Ikhsan Ibrahim, Nur Aisyah, Suaib Suaib","doi":"10.51601/ijhp.v4i2.329","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.329","url":null,"abstract":"Hyperglycemia is one of the problems of people with Diabetes Mellitus, poorly controlled hyperglycemia conditions can cause complications, one of which is impaired peripheral vascular flow which can cause diabetic wounds. Vascularization disorders can be prevented by Buerger Allen Exercise therapy and 3 Physical Therapy Modalities to increase Ankle Brachial Index (ABI) values. The purpose of this study was to compare the effect of Buerger Allen Exercise and 3 Physical Therapy Modalities on ABI values in people with type II Diabetes Mellitus. The design of this study was Quasi Experiment Pre and post test two groups with 15 respondents of group A given Buerger Allen Exercise intervention and 15 respondents of group B given 3 Physical Therapy Modalities intervention. The results showed that there was an increase in ABI values after intervention in both groups with the difference in the Buerger Allen Exercise group increase of 0.050 while the Modaliatas Physical Therapy group amounted to 0.113. In conclusion, there was an increase in ABI values in both groups after the intervention but group 3 Modaliatas Physical Therapy had a higher increase. Intervention 3 Modaliatas Physical Therapy can be recommended as one of the alternative therapies as a prevention of complications of peripheral arterial disease.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"37 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140449120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Education Factors, Parents' Occupation and Economic Status on the Incidence of Early Marriage in Young Women in Sigedong Village, Bumijawa District, Tegal Regency","authors":"Tika Nur Arifin, Elfira Sri Futriani","doi":"10.51601/ijhp.v4i2.241","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.241","url":null,"abstract":"Background: Marriage is a physical and spiritual bond between a man and a woman as husband and wife with the aim of forming a prosperous familyPurpose of Writing: To find out the relationship between educational factors, parents' occupation and economic status on the incidence of early marriage among young women in Sigedong Village, Bumijawa District, Tega Regency. by researchers in collecting data that is using secondary data. Research Results: There is a relationship between education, occupation, parents' economic status on the incidence of early marriage in young women in Sigedong Village, Bumijawa District, Tegal Regency. Conclusions and Suggestions: It is hoped that the results of this study can be used as a reference for female students about providing health education about early marriage and risks that occur for parents who are too early to marry their children so that they can be applied in community service.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"971 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140446456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Parents' Knowledge of Dental and Oral Health and the Incidence of Dental Caries in Nurul Hayat Islamic Kindergarten School Children in Kapuk Village, Cengkareng District North Jakarta","authors":"Syarina Ria, Olivia Nency","doi":"10.51601/ijhp.v4i2.294","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.294","url":null,"abstract":"Background Parents, especially mothers, have an important role in developing children's positive behavior towards dental and oral health. Parents' participation in maintaining children's dental and oral health can be implemented by paying attention to children's behavior regarding dental and oral health and children's eating patterns. Writing Objective: to determine the relationship of knowledge about oral and dental health with the incidence of dental caries in Islamic Kindergarten students at Nuruk Hayat, Kapuk Village, Cengkareng District, North Jakarta. Research Methods: The sample size in this study used a total side of 50 students of Nurul Hayat Islamic Kindergarten in Kapuk Village, Cengkareng District, North Jakarta. This study was to determine parents' knowledge about dental and oral health using a questionnaire conducted by interviewing parents and children of Nurul Hayat Islamic Kindergarten in Kapuk Village, Cengkareng District, North Jakarta. The data analysis used was univariate and bivariate analysis using the chi square test. Research Results The results showed that parents' knowledge of dental and oral health on the incidence of caries on the Chy-square test resulted in a P value of 0.00 <0.05, so the analysis was that there was a relationship between the history of parental knowledge about dental and oral health and the incidence of caries. The results of the OR calculation were 0.583, which means that the incidence of caries was 0.583 times lower with good parental knowledge about dental and oral health compared to parents with less knowledge (95% CI 0.362-0.941). Conclusions and Suggestions: It is hoped that the results of this study can be used as a reference for students about providing education to parents and children about oral and dental health.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"43 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140447539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Lavender Aromatherapy in First Trimester Pregnant Women with Emesis Gravidarum at TPMB Megawati in 2023","authors":"Olivia Nency, Megawati Megawati","doi":"10.51601/ijhp.v4i2.296","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.296","url":null,"abstract":"Background: Pregnant women with emesis gravidarum who use acupressure can reduce or even avoid the use of anti-nausea drugs which have the potential to have side effects. This can be considered as an effective non-pharmacological alternative in treating emesis gravidarum. Purpose of Writing: Knowing the Effectiveness of Lavender Aromatherapy in First Trimester Pregnant Women with Emesis Gravidarum at TPMB Megawati in 2023. Research Method: quasi-experimental research with pretest posttest with control group design. The independent variable in this study was lavender aromatherapy and the dependent variable was Emesis Gravidarum. taken by purposive sampling. Data analysis was carried out univariately and bivariately, to find out the difference in the Emesis Gravidarum score in the intervention and control groups in each group using wicoxo. Research Results The research results are known Asymp. Sig (2 – Talled) has a value of 0.000 because 0.000 <0.05, it can be concluded that the hypothesis is accepted. This means that there is a difference before and after giving lavender aromatherapy. The research results are known Asymp. Sig (2 – Talled) has a value of 1,000 because 0.000 > 0.05, it can be concluded that the hypothesis is rejected. This means that there is no difference before and after in the control group.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"47 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140447684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence Of Booklet On The Success Of Toilet Training In Children Aged 2-3 Years At Ra Bintang Zhafira Tulang Bawang Regency","authors":"Ranti Wulandari M, Sonda Nur Assyaidah","doi":"10.51601/ijhp.v4i2.327","DOIUrl":"https://doi.org/10.51601/ijhp.v4i2.327","url":null,"abstract":"Background: According to the Child Development Institute Toilet training, it is reported that 10 -20% of children aged 5 years, 5% of children aged 10 years, almost 2% of children aged 12-14 years, and 1% of children aged 18 years still wet the bed. Toilet training is an effort to train children to be able to control defecation (BAB) and urination (BAK) in their place (toilet). Education is one way to increase mothers' or parents' intellectual knowledge about toilet training. Education or health education can be provided using various methods and media, including: lectures, discussions, giving leaflets, booklets or direct practice related to the mother's needs. A booklet is a small book that contains writing, pictures or both. Research objective: to determine the effect of booklets on the success of toilet training in children aged 2-3 years at RA Bintang Zhafira, Tulang Bawang Regency. Research method: This research uses quantitative with a Quasy Experiment design with a one group pretest and posttest design. The population in this study was 32 mothers who had children aged 2-3 years and the sample taken was 32 respondents. The research was carried out at RA Bintang Zhafira, Tulang Bawang Regency in December 2023-January 2024. Data analysis was carried out univariate and bivariate (t test). Research results: it is known that the average success of toilet training before intervention was given to children aged 2-3 years was 8.0 and after intervention was given to children aged 2-3 years was 12.1. There is an influence of the booklet on the success of toilet training in children aged 2-3 years at RA Bintang Zhafira, Tulang Bawang Regency with p-value = 0.000 or p ≤ α (0.05). Conclusions and Suggestions: There is an influence of the booklet on the success of toilet training in children aged 2-3 years at RA Bintang Zhafira, Tulang Bawang Regency and suggestions for RA Bintang can provide health education to mothers who have toddler age children regarding the implementation of toilet training.","PeriodicalId":432290,"journal":{"name":"International Journal of Health and Pharmaceutical (IJHP)","volume":"137 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140445315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}