Oncology Journal of India最新文献_第10页

Prevention of cervical cancer: Role of vaccination and screening 预防子宫颈癌:疫苗接种和筛检的作用

Oncology Journal of India Pub Date : 2019-01-01 DOI: 10.4103/OJI.OJI_24_19

P. Priyadarshini, S. Majumdar, D. Parida

引用次数: 1

Accuracy of magnetic resonance imaging in evaluation of sellar and juxtasellar tumors 磁共振成像在鞍区及鞍旁肿瘤诊断中的准确性

Oncology Journal of India Pub Date : 2019-01-01 DOI: 10.4103/OJI.OJI_20_18

Pratisruti Hui, S. Parida, J. Mohanty, Mamata Singh, Pradosh Kumar Sarangi

{"title":"Accuracy of magnetic resonance imaging in evaluation of sellar and juxtasellar tumors","authors":"Pratisruti Hui, S. Parida, J. Mohanty, Mamata Singh, Pradosh Kumar Sarangi","doi":"10.4103/OJI.OJI_20_18","DOIUrl":"https://doi.org/10.4103/OJI.OJI_20_18","url":null,"abstract":"Background: Sellar and parasellar/juxtasellar regions are complex areas of the brain, and different varieties of tumors can occur in this area. Preoperative noninvasive diagnosis with magnetic resonance imaging (MRI) is essential for treatment planning. Aim of the Study: The aim of this study is to characterize MRI features of the sellar and juxtasellar tumors and to correlate MRI diagnosis with histopathological diagnosis in order to evaluate the efficiency of MRI. Materials and Methods: Patients with sellar and juxtasellar lesions who were operated during September 2015–August 2017 and the pathological reports were compared with the MRI findings retrospectively. Results: A total of 50 patients were enrolled in the study, and the mean age of presentation was 34.6 years. MRI-based radiological diagnosis showed 21 cases of pituitary macroadenoma, 15 cases of craniopharyngioma, 9 cases of meningioma, 2 cases of germinoma, 1 case of glioma, and 2 cases of epidermoid cysts. Histopathological correlation revealed MRI accuracy of 94.12%, 94%, 100%, 98%, 100%, and 100% for the diagnosis of pituitary macroadenoma, craniopharyngioma, meningioma, germinoma, glioma, and epidermoid cyst, respectively. One case each of pituitary macroadenoma and germinoma diagnosed on MRI comes out to be as craniopharyngioma after final histopathological correlation, whereas one case of craniopharyngioma turned out to be macroadenoma after final histopathological examination. Conclusions: The present study revealed a strong correlation between MRI and histopathological diagnosis for sellar and juxtasellar tumors. MRI is the modality of choice for characterizing sellar and suprasellar lesions.","PeriodicalId":431823,"journal":{"name":"Oncology Journal of India","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131174919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Squamous cell carcinoma arising from mature cystic teratoma of the ovary 由卵巢成熟囊性畸胎瘤引起的鳞状细胞癌

Oncology Journal of India Pub Date : 2019-01-01 DOI: 10.4103/OJI.OJI_3_19

Y. Devi, S. Mohanty, Deep Das, V. Sekar

引用次数: 0

Solid pseudopapillary tumor of head and body of pancreas with pure solid component – A case report with diagnostic dilemma 胰腺头体实性假乳头状瘤伴纯实性成分1例诊断困境

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/oji.oji_37_18

I. Dhal, S. Saxena, Mitali Swain

引用次数: 0

Metaplastic carcinoma of breast: A series of nine cases from a regional cancer center in Northeast India 乳腺癌的化生性癌:来自印度东北部地区癌症中心的9例病例

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_39_18

S. Mohanty, Y. Devi, Daffilyne Lyngdoh Nongrum, L. Singh, V. Sekar, Deep Das

{"title":"Metaplastic carcinoma of breast: A series of nine cases from a regional cancer center in Northeast India","authors":"S. Mohanty, Y. Devi, Daffilyne Lyngdoh Nongrum, L. Singh, V. Sekar, Deep Das","doi":"10.4103/OJI.OJI_39_18","DOIUrl":"https://doi.org/10.4103/OJI.OJI_39_18","url":null,"abstract":"Background: Metaplastic carcinoma of the breast (MCB) is a rare histological subtype of breast carcinoma containing glandular and nonglandular components with mixed epithelial and mesenchymal differentiations. Aim of the Study: The study aimed to report clinical, radiological and pathological profiles, treatment and outcome of patients diagnosed with MCB from a tertiary care institute along with literature review. Materials and Methods: Diagnosed cases of MCB were obtained from the record over a period of January 2010 to December 2017, and data were recorded in a structured pro forma. Results: A total of 9 (0.9%) cases of MCB were identified out of 1031 breast cancer patients with the median age of presentation of 53 years. The palpable lump was the most common presentation (77.78%). The mean tumor size was 4.9 cm in greatest dimension. Sonographically, most of the lesions were solid (44.44%) followed by cystic (33.33%). Mammographically, microcalcifications were absent in eight cases. Histologically, 55.56% of cases were purely epithelial subtype (3: pure squamous and 2: adenosquamous) and 4 (44.44%) cases were mixed epithelial and mesenchymal subtypes (3: carcinosarcoma and 1: invasive lobular carcinoma with sarcomatous component and osseous metaplasia). All the cases were having triple-negative receptor status. Modified radical mastectomy (MRM) was performed in all cases and 33.33% of cases had axillary node positive. About 77.88% and 88.89% of cases received adjuvant chemotherapy and adjuvant radiotherapy, respectively. At median follow-up of 27 months, local recurrence and distant metastases were seen in 1 and 3 cases, respectively. At present, 33.33%, 22.22%, and 44.45% of patients were died, alive, and lost for follow-up, respectively. Conclusion: MCB is a rare histologic subtype of breast cancer with larger tumor size at presentation and MRM is the preferred surgical procedure over breast conservation surgery. Long-term and regular follow-up is necessary to know the outcome.","PeriodicalId":431823,"journal":{"name":"Oncology Journal of India","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129563683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Radioimmunotherapy: Is it future? 放射免疫疗法:是未来吗?

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_41_18

T. Sahoo

引用次数: 0

Patterns of lymph node involvement and role of common iliac lymphadenectomy in early-stage cervical cancers: A retrospective analysis from tertiary care cancer center in Eastern India 淋巴结受累模式和普通髂淋巴结切除术在早期宫颈癌中的作用:来自印度东部三级保健癌症中心的回顾性分析

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_34_18

M. Mohapatra, Rohini V. Kulkarni, B. Nayak, Swathi Pai, A. Padhy, S. Giri, Janmejay Mahapatra, J. Parija

{"title":"Patterns of lymph node involvement and role of common iliac lymphadenectomy in early-stage cervical cancers: A retrospective analysis from tertiary care cancer center in Eastern India","authors":"M. Mohapatra, Rohini V. Kulkarni, B. Nayak, Swathi Pai, A. Padhy, S. Giri, Janmejay Mahapatra, J. Parija","doi":"10.4103/OJI.OJI_34_18","DOIUrl":"https://doi.org/10.4103/OJI.OJI_34_18","url":null,"abstract":"Aims: The aim of the study was to analyze the patterns of lymph node metastasis in early cervical cancer cases operated and to measure the metastatic burden in common iliac nodes and subsequently assess the need for its dissection. Materials and Methods: The study included all the cases of early carcinoma of cervix (Stage IA to IIA) that were operated in our institute. The cases with positive (metastatic) lymph nodes were isolated incorporating the data in tabular form and the patterns of lymph node metastasis analyzed with special reference to common iliac node involvement. Results: A total of 250 patients were operated in our study cohort and 50 cases (20%) had positive lymph node metastasis. External iliac nodes (58%) were most commonly involved, whereas 20% of cases had common iliac nodal involvement and isolated common iliac nodal involvement was seen only in 8% of these cases. Among all the lymph node positive cases, 74% had two or more of the three intermediate-risk factors including deep stromal invasion, lymphovascular space invasion positivity, or large-sized lesion (>4 cm). All the isolated common iliac lymph node positive cases had either positive parametrium or at least two intermediate-risk factors. Conclusion: Isolated common iliac nodal involvement being very low (8%), and this isolated involvement having been demonstrated only in cases with other risk factors; the role of common iliac lymph node dissection in early-stage cancer cervix becomes questionable.","PeriodicalId":431823,"journal":{"name":"Oncology Journal of India","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129633902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extrapulmonary inflammatory myofibroblastic tumor at different sites with histopathology and immunohistochemical analysis: A case series 肺外炎性肌纤维母细胞瘤不同部位的组织病理学和免疫组织化学分析:一个病例系列

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_38_18

S. Saxena, I. Dhal, Anisha Mohanpuria, J. Garg, S. Karnik, Bhushan Khedkar

{"title":"Extrapulmonary inflammatory myofibroblastic tumor at different sites with histopathology and immunohistochemical analysis: A case series","authors":"S. Saxena, I. Dhal, Anisha Mohanpuria, J. Garg, S. Karnik, Bhushan Khedkar","doi":"10.4103/OJI.OJI_38_18","DOIUrl":"https://doi.org/10.4103/OJI.OJI_38_18","url":null,"abstract":"Background: Inflammatory myofibroblastic tumor (IMT) is a rare entity and has wide anatomical sites of origin. Because of overlapping clinical and radiological features, histopathology study followed by immunohistochemistry (IHC) analysis is necessary for confirmation of the diagnosis. Aim of the Study: This study aimed to present the demographic, histopathological, and IHC analysis of patients diagnosed with extrapulmonary IMT. Materials and Methods: Patients diagnosed with extrapulmonary IMT were analyzed from January 2017 to July 2018. Results: A total of six cases were included in our series, with the mean age of presentation being 37 years. Male-to-female ratio was 1:2. The primary site of origin was distributed as follows: two cases of face and neck (one mandible and one naso-orbital), three cases of abdominal location (one spleen, one periaortic node, and one paraaortic node), and one case of cervix. There was no local invasion or metastasis found. Microscopically, all the cases revealed a common pattern of finding of the presence of intersecting fascicles of spindle cells with intervening collagenous to myxoid matrix along with infiltration of plasma cells and aggregates of lymphocytes. There were no atypical cells or mitosis in all the cases. All six cases were smooth muscle actin and vimentin positive and S100, desmin, and cytokeratin negative on IHC study. All the cases were anaplastic lymphoma kinase (ALK) negative, except one case with cervical primary where it was positive for ALK-1. Conclusion: Extrapulmonary IMT is a rare entity with diagnosis by exclusion on histopathological examination, and IHC should be done for confirmation of the diagnosis as well as ALK expression status.","PeriodicalId":431823,"journal":{"name":"Oncology Journal of India","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121237960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Papillary cystic variant of acinic cell carcinoma of parotid with preoperative diagnostic difficulty on fine-needle aspiration cytology: A case report 腮腺腺泡细胞癌乳头状囊性变异体术前细针穿刺细胞学诊断困难1例

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_35_18

S. Dhar, S. Rautray, S. Majumdar, Asaranti Kar, D. Parida

引用次数: 0

Unicentric hyaline vascular type of castleman disease of the renal hilum with diagnostic dilemma: A case report and review of literature 肾门单中心透明血管型castleman病诊断困境:1例报告及文献复习

Oncology Journal of India Pub Date : 2018-10-01 DOI: 10.4103/OJI.OJI_36_18

A. Adhya, Manas Ranjan Pradhan

引用次数: 0