Le Journal médical libanais. The Lebanese medical journal最新文献

{"title":"Migration intravésicale d’un dispositif intra-utérin Cas clinique et revue de la littérature.","authors":"Jawad Feghali,&nbsp;Ali Bourgi,&nbsp;Khalil Armache","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intravesical migration of intrauterine device (IUD) is a rare complication. We report a case of IUD that migrated into the bladder of a 31-year-old woman who had it for four years, and presented with irritative bladder symptoms following a miscarriage. The diagnosis was first suspected by an ultrasound and confirmed by cystoscopy. Treatment consisted by removing the IUD endoscopically. This case shows the importance of following the medical instructions for the placement of an intrauterine device, and regularly verifying its localization in order to reduce the incidence of uterine perforation and extra-uterine migration.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 4","pages":"238-41"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36174928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SYNDROME DES ANTIPHOSPHOLIPIES. À PROPOS DE 30 CAS.","authors":"Olga Nahas,&nbsp;Lina Serhal,&nbsp;Myrna Germanos,&nbsp;Stéphanie Abou Nakad,&nbsp;Georges Maalouly,&nbsp;Fady Haddad,&nbsp;Aline TohmÉ","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze clinical and immuno- logic manifestations of Lebanese patients with the antiphos- pholipid syndrome (APS).</p><p><strong>Patients and methods: </strong>Our study was retrospective and was done on hospitalized patients be- tween 2001 and 2013. All these patients fulfilled the interna- tional criteria for diagnosis (Sydney criteria).</p><p><strong>Results: </strong>Of the 30 patients selected, we noticed a female predominance (sex ratio: 2.75). The age at diagnosis ranged between 9 and 72 years with a mean age of 43 - 17 years. \"Primary\" APS was present in 70% of patients; APS was associated with systemic lupus erythematosus (SLE) in 23% of patients, with a mixed connective tissue disease in 3% and systemic vasculitis in 3%. A catastrophic APS occurred in 3 cases (10%). The most com- mon presenting manifestations were deep venous thrombosis (53%), pulmonary embolism (33%) and stroke (13%). Eleven patients (37%) had venous thrombosis, 7 (23%) had arterial thrombosis alone and 7 (23%) both arterial and venous throm- bosis. Deep venous thrombosis occurred mostly in the lower limbs (70%) whereas arterial thrombosis occurred in cerebral arteries in 50% of cases. The most common fetal complica- tions were early fetal loss (62.5%). Anticardiolipin antibodies were the most frequently identified antibodies (83%), followed by anti-p2GPI (70%) and anticoagulant lupus (11%). An effec- tive anticoagulation by anti-vitamin K was performed in 29 pa- tients. Corticosteroids were prescribed in 13 cases and were associated to immunosuppressant drugs in 6 cases of second- ary APS and the 3 catastrophic APS. The patients with cat- astrophic APS received also intravenous immunoglobulin. Response to treatment was favorable in 86% of patients with a mean follow up of 6 4 years. We deplored 4 deaths, 2 with- in the catastrophic APS.</p><p><strong>Conclusion: </strong>The APS does not seem to have particular features in Lebanon. The primary form seems to be the most common. It is important to diagnose this syn- drome earlier before the onset of serious complications.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"78-83"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CIRCULATING microRNAs: POTENTIAL BIOMARKERS IN CANCER DETECTION, DIAGNOSIS AND PROGNOSIS.","authors":"Nader Makarem,&nbsp;Ahmad Mourad,&nbsp;Farah J Nassar,&nbsp;Rihab Nasr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A large family of small 18-25 nucleotide long non coding RNA molecules now known as microRNA (miRNA) was described two decades ago, and has been recently es- tablished as post-transcriptional gene regulators. miRNAs were shown to be involved in the regulation of diverse phys- iological and developmental processes. Moreover, dysregula- tion of specific miRNAs has been implicated later in several pathologies including cancer. Owing to their presence and stability in body fluids, miRNAs have been investigated as novel circulating non-invasive biomarkers. Accordingly, their role as potential diagnostic, prognostic or predictive biomark- ers for many cancer types has recently emerged. This review tackles the use of circulating miRNAs in cancer detection, diagnosis and prognosis, giving examples using common solid tumors and discussing the advantages of their use, the challenges facing this novel circulating biomarker and recorn- mendatidns to overcome them.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"116-122"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36685664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AN ATTEMPT TO HALT THE EVER-INCREASING PREVALENCE OF MORBIDITIES RESULTING FROM EXCESS DIETARY SODIUM INTAKE. The Lebanese Experience.","authors":"Mohamad M Almedawar,&nbsp;Hussain A Isma'Eel,&nbsp;Lara Nasreddine,&nbsp;Ammar Olabi,&nbsp;Kamal F Badr,&nbsp;M Samir Arnaout","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"63-64"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36696971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AUTISM IN REVIEW.","authors":"Simone Khalifeh,&nbsp;Walid Yassin,&nbsp;Silva Kourtian,&nbsp;Rose-Mary Boustany","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autism spectrum disorders are a group of neurodevelopmental disorders characterized by impaired verbal and/or nonverbal communication in addition to repeti- tive stereotypical behaviors. We present a review article on this topic. Criteria for diagnosis are defined by the Diagnos- tic and Statistical Manual of Mental Disorders Fifth Edition (DSM 5). Abnormalities at the level of synapses, including newly described genetic perturbations, have been implicated in the pathogenesis of autism. Non-invasive modalities like Diffusion Tensor Magnetic Resonance Imaging have identi- fied white matter tract involvemeht in the brains of autistic in- dividuals. Early and intensive intervention impact prognosis. Risperidone and aripiprazole are FDA approved for irritability in autism although no known medication relieves core symp- toms of social and communication impairment. Fluoxetine is used to decrease anxiety in autistic patients.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"110-115"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RELATIONSHIP OF PERSONALITY TRAITS WITH ANXIETY, DEPRESSIVE AND PTSD SYMPTOMATOLOGY AND ACADEMIC PERFORMANCE. Experience with an Arab college student sample.","authors":"Fawziyah A Al-Turkait,&nbsp;Jude U Ohaeri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The objective was to highlight the profile of Eysenck Personality Questionnaire traits of a sample of Arab college students, and assess the relationship of trait scores with gender, age and symptoms of anxiety, depression, PTSD and grade point average (GPA) score. Similar reports from the Arab world were restricted to neuroticism/extraversion and rarely involved traumatic experience and psychosocial performance.</p><p><strong>Methods: </strong>Participants (N = 624) were Kuwaiti national college students who completed, in class, the EPQ- 90, Hopkins Symptoms Checklist, and the PTSD Checklist.</p><p><strong>Results: </strong>Men had higher psychoticism (p < 0.004) and extra- version (p <0.03) scores, while women had higher neuroticism (p < 0.001) and lie scale scores (p < 0.001). Students with the lowest GPA had the highest scores for psychoticism (p< 0.01). Psychoticism and neuroticism were significantly correlated with each other, but negatively with extraversion and lie scale. The correlations of psychopathology were strongest with neu- roticism and psychoticism; and negative with extraversion and the lie scale. In regression analyses, the dominant predictor of psychopathology was neuroticism. With neuroticism as covari- ate, the sex difference in depression scores was no longer sig- nificant.</p><p><strong>Conclusions: </strong>Our findings support the usefulness of neuroticism as reflecting characteristic level of distress; and a combination of high neuroticism and low extraversion as vul- nerability marker for psychopathology. Psychoticism needs further study as a marker of psychosocial underachievement.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"100-106"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATION OF MULTIDISCIPLINARY TEAM MEETINGS IN URO-ONCOLOGY.","authors":"Raghid El Khoury,&nbsp;Mario Chahrouri,&nbsp;Charbel Hachem,&nbsp;Joseph Abi Zeid,&nbsp;Paul El Alam,&nbsp;Maher Abdessater","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to examine the impact of multidisciplinary team meetings on the management decisions for urological cancers. A pro- spective study was conducted.</p><p><strong>Methods: </strong>The study popu- lation is cases presented to multidisciplinary teams at Notre- Dame de Secours University Medical Center between July 2012 and July 2014. Data was collected by a standard pro forma.</p><p><strong>Results: </strong>189 cases were presented in multidisci- plinary meetings during the study period. Results of this study showed that multidisciplinary team meetings change management decisions in 40.7% of cases. Change in man- agement decisions was mainly significant in testicular can- cer (57.1%), prostate cancer (42.7%) and bladder cancer (38.2%), with less important changes in renal cancer (33.3%). Prostate cancer cases with Gleason score 7 (51.7%) and bladder tumors with TNM ;t T2 (85.7%) were the most mod- ified in their respective groups.</p><p><strong>Conclusion: </strong>Multidiscipli- nary team meetings have a major impact in therapeutic de- cisions taken by urologists for newly diagnosed urological cancers.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"84-90"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EARLY INCREASE of CA 19-9 in ADVANCED PANCREATIC CANCER RECEIVING FOLFIRINOX. Is it a sign of efficacy?.","authors":"Samer Tabchi,&nbsp;Hampig R Kourie,&nbsp;Fadi Farhat,&nbsp;Joseph Kattan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Advanced pancreatic cancer (APC), one of the most aggressive tunors, was considered to be resistant to chemotherapy for decades. FOLFIRINOX (5-FU, leucovorin, iNinotecah and oxaliplatin) regimen showed an improvement of quality of life and overall sUrvival.ir APb patients with good performance status (ECOG < 2).</p><p><strong>Material and methods: </strong>Seven patients diagnosed with APO, during a six-month period, received FOLFIRINOX as first line treat- ment. Tumor measurement Was assesed every two months and CA 19-9, tHe specific tumor marker of pahcteatid can6er, was assessed every two wedks at every cycle.</p><p><strong>Results: </strong>Three patients ouf of seven receiving FOLFiRINOX dtpe- riented an early And transitory increase of CA 19-9 after th6 first two cybles resulting ih a considerable response with a median survival of 15 mnths and suggesting a fhdel of fdmor release syndrome.</p><p><strong>Conclusion: </strong>This phenoMenon of early and transitory increase of CA 19-9 in APC could reflect the high efficacy of FOLFIRINOX and could predict better out- come in these patients.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"97-99"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Not Available].","authors":"Edgard Gédéon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"107-109"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Not Available].","authors":"Maya Sammour,&nbsp;Fouad Fayad,&nbsp;Nelly Ziadé,&nbsp;Rami Abiad,&nbsp;Soha Haddad-Zebouni","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Musculoskeletal ultrasound has evolved throughout the last decade. This procedure allows accurate corticosteroid injections guidance. Precision is much higher than the infiltration performed blindly or under fluoro- scopy. The purpose of our approach is to describe our tech- nique in ultrasound-guided infiltration of the shoulder with an overview of the results.</p><p><strong>Material and method: </strong>123 cases of ultrasound-guided infiltration of the shoulder were selected in our institution from July 2011 to June 2012. They are divided into sub-acromial sub-deltoid bursitis, biceps tenosynovitis, acromioclavicular osteoarthritis, adhesive capsulitis and cal- cific tendinosis lavage and aspiration.</p><p><strong>Results: </strong>The infiltra- tion technique and the sonographic appearance in each con- dition are described. The rate of improvement is estimated between 70 and 80%.</p><p><strong>Conclusion: </strong>The ultrasound-guided infiltration provides an accurate and minimally invasive thera- peutic option before any surgery. Recovery and socio-profes- sional integration prove to be optimal and fast.</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"64 2","pages":"91-96"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36684677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}