Eurasian Journal of Pulmonology最新文献

{"title":"Comparing respiratory symptoms and spirometry disorders among healthy people and workers of indoor swimming pools: A case–control study","authors":"Z. Yazdi, M. Zohal, S. Abkenar","doi":"10.4103/ejop.ejop_3_19","DOIUrl":"https://doi.org/10.4103/ejop.ejop_3_19","url":null,"abstract":"BACKGROUND: The water disinfection of swimming pools through chlorination method causes unwanted changes such as chlorine-containing byproducts within the air, which might affect the swimming pool workers' respiratory health. The present study is aimed to determine the frequency of respiratory symptoms and spirometry abnormalities among the workers of indoor swimming pools (instructors and lifeguards). MATERIALS AND METHODS: The present case–control study was conducted on forty individuals working in indoor swimming pools and forty others working at chlorine-exposure-free jobs as the control group. A questionnaire, including demographic information, smoking information, respiratory symptoms, and years of employment in the swimming pool, was completed for every participant. All the personnel, as well as the participants in the control group, underwent pulmonary examinations and spirometry tests. Then, the obtained data were analyzed using the SPSS 16 software as well as the statistical tests, including t-test, Chi-square test, correlation coefficient, and regression analysis. RESULTS: The mean age of the participants in the case and control groups was 32.3 and 32.5 years, respectively. Both the case and control groups consisted of 18 males (45%) and 22 females (55%). Among the respiratory symptoms, lacrimation, rhinorrhea, sneeze, throat irritation, and chest tightness were significantly higher in the case group than that of the control group (15%, 80%, 35%, 57.5% and 72.5% vs. 0%, 40%, 12.5%, 2.5% and 27.5%, respectively). The pulmonary examinations indicated a statistically significant difference between the two groups in terms of the prevalence of wheeze and rhonchi (P = 0.014 and 0.006, respectively). Moreover, showing a statistically significant difference, the forced vital capacity (FVC) and forced expiratory volume in 1 s/FVC indicators were lower in the case group than the control group (P = 0.04 and 0.016). CONCLUSION: Regarding the findings, there was a direct relationship between working in indoor swimming pools and the prevalence of respiratory symptoms and pulmonary dysfunction.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"14 - 18"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47282248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and tolerability of antifibrotic agents in idiopathic pulmonary fibrosis: An experience from Turkey","authors":"O. Turan, Bunyamin Sertoğullarından","doi":"10.4103/ejop.ejop_74_20","DOIUrl":"https://doi.org/10.4103/ejop.ejop_74_20","url":null,"abstract":"INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease associated with poor prognosis. Antifibrotic drugs have come into use in the treatment of IPF, for which no effective therapeutic option existed until recently. This study makes an evaluation of IPF patients receiving pirfenidone or nintedanib as treatment. MATERIALS AND METHODS: This retrospective study included IPF patients who received antifibrotic therapy in our outpatient clinic between 2017 and 2020. The demographics, clinical symptoms, spirometric results, modified Medical Research Council (mMRC) and Leicester Cough Questionnaire (LCQ) scores, drug-related side effects, and treatment responses (at 6 months) were recorded. RESULTS: There were 52 patients (32:male-61.5% and 20:female-38.5%) with mean age of 70.65 ± 9.18. The most common presenting symptoms were dyspnea (86.5%) and cough (61.5%). The patients received pirfenidone (n = 31) and nintedanib (n = 21) therapies. The rate of side effects was 53.1%. At the 6-month control examination, 66% of the patients reported symptom relief. No significant difference was found in clinical symptoms, mMRC, respiratory parameters, or occurrence of side effects between the two treatment groups (P = 0.936, 0.393, 0.124, and 0.962, respectively). There was a stastistically significant improvement at LCQ score in patients treated with pirfenidone (P < 0.01). At the 6th month of the treatment process, there was a statistically significant improvement in the mMRC, LCQ scores, and forced vital capacity level (P < 0.01 all). CONCLUSION: The outcomes of antifibrotic therapy in IPF are particularly promising in terms of relieving clinical symptoms and the preservation of lung capacity. IPF patients receiving pirfenidone as a treatment seems to have a significant improvement in cough-related health quality.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"59 - 63"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43773559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could FEF 25–75 levels or blood eosinophil counts predict the presence or absence of bronchial hyperreactivity?","authors":"K. Aksu, Ali Fırıncıoğluları, Ezgi Erdem, F. Aksu","doi":"10.4103/ejop.ejop_64_21","DOIUrl":"https://doi.org/10.4103/ejop.ejop_64_21","url":null,"abstract":"BACKGROUND AND AIM: The relationship between bronchial hyperreactivity (BHR) and lung function parameters and blood eosinophilia in suspected asthmatics is not clear. This study aimed to investigate the relationship between FEF 25-75 values and blood eosinophilia levels and BHR in patients with asthma symptoms. MATERIALS AND METHODS: Demographic and spirometric data and blood eosinophil counts were compared between patients with and without significant BHR. Receiver operating characteristic (ROC) curve analysis was performed to evaluate FEF25–75 and blood eosinophil count cutoff values to distinguish BHR in these patients. RESULTS: According to the data of 894 patients, with BHR in 182 (20.4%), FEF25%–75% were significantly lower and blood eosinophil counts were significantly higher in patients with BHR. The best discriminatory values to assess the nonevident BHR were 64.5% for FEF25–75 (sensitivity: 94.2% and specificity: 18.7%) and 164/μL for blood eosinophil count (sensitivity: 59.6% and specificity 60.2%). The rate of nonevident BHR was significantly different between patients with FEF25–75 <65% and ≥65% (54.7% and 81.9%, respectively, P < 0.001). Although significant, the rates of nonevident BHR in patients with blood eosinophil counts below and above the cutoff (85.5% and 72.6%, respectively, P = 0.012) were not as different as the rates in patients with FEF25–75 values below and above the cutoff. CONCLUSION: FEF25–75 is associated with BHR in patients with asthma symptoms. Nonevident BHR is more likely if FEF25–75 ≥65 in suspected asthmatics. However, blood eosinophil count is not helpful in predicting the absence of BHR in suspected asthmatics.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of ultrasound in the assessment of diaphragm function in patients with chronic obstructive pulmonary disease","authors":"P. Ramachandran, U. Devaraj, Louis Varghese, K. Venkatanarayana, U. Krishnaswamy, G. D'Souza","doi":"10.4103/ejop.ejop_39_19","DOIUrl":"https://doi.org/10.4103/ejop.ejop_39_19","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) characterized by irreversible airway obstruction, has numerous systemic complications including skeletal muscle dysfunction. Diaphragm, an important muscle of respiration, is also affected and it has far-reaching impact on morbidity. The study of diaphragm in individuals with COPD is challenging. Although the use of ultrasonography to study the function of diaphragm is in its nascent stage, it seems to be a promising tool for a comprehensive evaluation of diaphragm in COPD patients. This article reviews the available literature on the use of US in study of diaphragm on individuals with stable COPD.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"1 - 9"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45912150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitrofurantoin-related interstitial lung disease: Case report and literature review","authors":"Emine Arguder, Osama Abuzaina, A. Karalezli","doi":"10.4103/ejop.ejop_7_19","DOIUrl":"https://doi.org/10.4103/ejop.ejop_7_19","url":null,"abstract":"Nitrofurantoin is an antimicrobial agent commonly used for urinary tract infections. This drug may cause pulmonary toxicities, the manifestations of which range from acute self-limiting reactions to chronic pathologies. Here, we report the case of a 72-year-old male who was admitted with progressive cough and dyspnea for 4 months. On physical examination, his respiratory rate was 26/min and oxygen saturation was 84% at rest while breathing room air. Chest examination revealed bilaterally fine crackles. His thorax computed tomography showed bilateral widespread ground-glass opacities and interlobular and intralobular septal thickening. His blood test revealed antinuclear antibody positivity. He had been using nitrofurantoin for a long time for urinary tract infection. He had a high score on Naranjo Adverse Drug Reaction Probability Scale. When he was a diagnosed, he had a respiratory failure due to lung damage. Patients using nitrofurantoin should be followed up closely for drug toxicity.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"64 - 66"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48487576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of autologous blood pleurodesis versus talc pleurodesis in symptomatic pleural effusions: A randomized trial","authors":"M. Metintaş, H. Yıldırım, A. Guntulu, Gulden Sari, S. Metintaş","doi":"10.4103/ejop.ejop_23_20","DOIUrl":"https://doi.org/10.4103/ejop.ejop_23_20","url":null,"abstract":"PURPOSE: This study aimed to compare the efficacy and safety of autologous blood pleurodesis with talc pleurodesis in patients with symptomatic pleural effusion. METHODS: This is a prospective, randomized, noninferiority trial. The smallest sample size was determined as 26 for each group by power analyses. For pleurodesis, 5 g of talc and 2 ml/kg blood were administered through the chest catheter. The success rate and complication were recorded in the 1st month after the procedures. The effect of the procedure on the successful pleurodesis was analyzed by univariate and then multivariate logistic regression analysis. RESULTS: A total of 60 patients were randomized. After randomization, 6 patients withdrew from the study. The overall success rate of pleurodesis was 72.0% in the autologous blood group and 69.0% in the talc group (P = 0.903). The most common complications were fever and pain, and both were higher in the talc group (P = 0.030 and P = 0.001, respectively). For successful pleurodesis, complete lung expansion and catheter duration (<7 days) were important factors in the talc group and in the autologous blood group, respectively (P = 0.001 and P = 0.034). The effect of the procedure on pleurodesis success was not significant (odds ratio [95% confidence interval): 1.51 [0.40–5.77]; P = 0.548) after adjustment for lung expansion and catheter duration. CONCLUSION: Autologous blood pleurodesis is a simple, inexpensive, effective procedure and no related to significant adverse events for patients with recurrent symptomatic pleural effusion. Especially, it can be preferred in patients with incomplete lung expansion. Further studies are required to confirm the results of this study.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"25 - 31"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47858606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The frequency of hyponatremia during the course of small cell lung cancer and its effect on prognosis","authors":"M. Şener, Ayperi Öztürk, M. Gürbüz, A. Yılmaz","doi":"10.4103/ejop.ejop_44_21","DOIUrl":"https://doi.org/10.4103/ejop.ejop_44_21","url":null,"abstract":"BACKGROUND AND AIM: Small‐cell lung cancer (SCLC) is fast‐growing disease with high mortality and prognosis is worse when hyponatremia develops. In our study, we aimed to determine the frequency of hyponatremia in SCLC and the relationship with the prognosis. MATERIALS AND METHODS: Patients diagnosed with SCLC between 2012 and 2017 were retrospectively screened. Stages, hyponatremia levels, and survival times were recorded. RESULTS: A total of 466 patients diagnosed with SCLC, 423 (90.8%) of whom were male were included in the study. The average age was 67 ± 10 years. About 126 (27%) of the patients were hyponatremic and 340 (73%) were normonatremic. Hypertonic saline treatment was performed in 52 (41.3%) patients. In total, hyponatremia improved in 49.2% (n = 62). While the expected survival means were 12.6 months in those with improved hyponatremia, 5.0 months in those with not improved, and 12.3 months in the normonatremic group. Survival in the group of whom hyponatremia could not be corrected was found to be statistically different (P < 0.05). CONCLUSION: The improvement of hyponatremia was found to be a positive independent factor on the survival of SCLC.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemotherapy given lung cancer in intensive care unit","authors":"Aybuke Kekecoglu, B. Fikri, Özkan Devran, M. Haliloğlu, A. Kosar","doi":"10.4103/ejop.ejop_7_20","DOIUrl":"https://doi.org/10.4103/ejop.ejop_7_20","url":null,"abstract":"Lung cancer is the leading cause of cancer-related death among all types of cancers. In lung cancer patients, hospitalization rates in intensive care units (ICUs) are gradually increasing due to both illness- and treatment-related complications. A 61-year-old male patient who had undergone radiotherapy for small cell lung cancer (SCLC) was admitted to the ICU on the 3rd day of his treatment because of hypercapnic respiratory failure. High-flow oxygen therapy was started. The mass lesion showed rapid progression. Chemotherapy was performed for SCLC which is a chemosensitive tumor.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"23 1","pages":"72 - 75"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44505722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the sleep quality of patients admitted to the internal medicine outpatient clinic","authors":"I. Kirhan, Fatih Uzer","doi":"10.4103/ejop.ejop_15_20","DOIUrl":"https://doi.org/10.4103/ejop.ejop_15_20","url":null,"abstract":"AIM: This study aimed to determine the sleep quality and the factors affecting sleep quality in patients admitted to the internal medicine outpatient clinic. MATERIALS AND METHODS: The study was conducted between July 1, 2019, and July 15, 2019, with a face-to-face questionnaire administered to the patients who applied to the internal medicine outpatient clinic of Harran University. A descriptive questionnaire, Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were used in the study. RESULTS: One-hundred and twelve (48.0%) male and 121 (51.9%) female patients with a mean age of 38.5 ± 16.3 years (18–86 years) were included in the study. The total PSQI mean was 4.9 ± 3.0 and the score range was 0–15. The rate of those with poor sleep quality was 48.9%. The mean score of ESS was 5.0 ± 3.6, and 12 (30%) patients admitted to the outpatient clinic experienced excessive sleepiness during the day. Gender of the participants (P = 0.800), income level (P = 0.113), the size of the house they were living in (P = 0.783), body mass index (BMI) (P = 0.491), and comorbid diseases (P = 0.803) did not affect the sleep quality; the number of people living in the same house affected the sleep quality (P CONCLUSION: We found that almost half of the patients admitted to the internal medicine outpatient clinic had poor sleep quality. We also found that as the number of people living in the same home decreases, sleep quality deteriorates.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"22 1","pages":"163"},"PeriodicalIF":0.2,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43948268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated pulmonary artery vasculitis","authors":"M. Ağca, B. Yıldızeli, E. Bozkurtlar, S. Yavuz, T. Sevim","doi":"10.4103/ejop.ejop_93_19","DOIUrl":"https://doi.org/10.4103/ejop.ejop_93_19","url":null,"abstract":"We present a unique case of a 26-year-old woman, which first evaluated as sarcoma or thromboembolic events with their clinical and radiological similarities of the pulmonary artery but diagnosed as isolated pulmonary artery vasculitis after endarterectomy with the help of histopathological examinations. After the endarterectomy procedure, the other causes that may lead to vasculitis had been excluded. The patient had the immunosuppressive therapy after the procedure, and her control computerized tomography revealed that the lumen of the pulmonary artery was wide open. Isolated pulmonary artery vasculitis must be considered as a differential diagnosis when a filling defect of the pulmonary artery had been detected without other systemic findings.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"22 1","pages":"180"},"PeriodicalIF":0.2,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42784274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}