Turkish Journal of Endocrinology and Metabolism最新文献

{"title":"Do We Neglect the Risk of Fracture","authors":"B. E. Bilir, B. Bilir","doi":"10.25179/tjem.20182202-p098","DOIUrl":"https://doi.org/10.25179/tjem.20182202-p098","url":null,"abstract":"Objective: Osteoporosis is a common metabolic bone disease. All women over the age of 65, all men over the age of 70 and the younger cases having some other risk factors are recommended to be screened for osteoporosis. In this study, we tried to show how much of the cases that were recommended to be screened had already been evaluated by DEXA. Methods: The age, height, weight and osteoporosis risk factors data of 125 cases, who admitted to our endocrinology out-patient clinics between October 2017 and February 2018 and must already been screened, were recorded. The cases were questioned whether their bone mineral density was assessed with DEXA previously. Fracture risk situations were analyzed by means of Fracture Risk Assessment Tool (FRAX) adapted for Turkey. The mean calculated risk of hip and major osteoporotic fractures and the frequency of each risk factor were assessed using the SPSS-21 statistical software program. Results: A total of 125 cases (106 female and 19 male) aged between 47 and 85 were evaluated with a mean age of 68. The means of weight and height were 76.08 kg and 155.2 cm respectively, 92% of the patients were non-smokers and any of the cases did not use alcohol regularly. Four cases were on glucocorticoid treatment and six cases were diagnosed with rheumatoid arthritis, 59.2% of cases had a secondary cause (8 cases were on aromatase inhibitor therapy for breast cancer, 1 had hypoparathyroidism, 4 had primary hyperparathyroidism, 15 had premature ovarian failure, 14 cases were thyrotoxic that 5 of them were iatrogenic thyrotoxicosis because of differentiated thyroid carcinoma treatment). While there was a personal history of fractures in 27.2% of cases, the parental fracture history was present in 8% of cases. While the mean 10-year-major osteoporotic fracture risk calculated by the FRAX scoring system was 6.05% (2.5-49), the mean risk of hip fracture was 1.6% (0.2-40). The percentage of those evaluated with DEXA previously despite the current indication for osteoporosis screening was only 55.5%. According to the FRAX calculation system, 24.8% of our cases were in high risk group for fracture, but only 48.4% of these cases were evaluated with DEXA. Conclusion: In our outpatient clinics, we neglect evaluating the risk of fracture which has so severe economical and emotional burden after it develops.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"1 1","pages":"44-44"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75650103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vandetanib Experience in a Patient with Ectopic Cushing Syndrome in Metastatic Medullary Thyroid Cancer","authors":"Ş. Akın, S. Akın, O. Kupik","doi":"10.25179/TJEM.20182202-P188","DOIUrl":"https://doi.org/10.25179/TJEM.20182202-P188","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"63 3 1","pages":"66-66"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77585701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Nontraditional Biochemical Markers and Their Relation to the Level of Fasting Glycemia in Patients with Type 2 Diabetes Mellitus","authors":"H. Nimmanapalli, Pullaiah Pasupuleti, Suresh Vakkakara, S. Pvln","doi":"10.25179/TJEM.2018-61752","DOIUrl":"https://doi.org/10.25179/TJEM.2018-61752","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"56 1","pages":"225-230"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84527985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: The Efficacy of Zolendronic Acid in Patients with Osteogenesis Imperfecta","authors":"M. Keskin, A. Koca, M. Dağdeviren, D. Ertuğrul, M. Altay","doi":"10.25179/TJEM.20182202-P89","DOIUrl":"https://doi.org/10.25179/TJEM.20182202-P89","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"49 1","pages":"43-43"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72894632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Papillary and Medullary Carcinoma in the Thyroid Gland","authors":"R. Uçler, G. Sönmez, S. Yıldız","doi":"10.25179/TJEM.20182202-P128","DOIUrl":"https://doi.org/10.25179/TJEM.20182202-P128","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"37 1","pages":"52-52"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76010497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Saffron (Crocus sativus) Aqueous Extract on TNF-α Levels in Liver, Kidney, and Lens Tissues of Diabetic Rats","authors":"M. Ashrafi, Zahra Afsar, H. Erjaee, S. Nazifi","doi":"10.25179/TJEM.2018-59710","DOIUrl":"https://doi.org/10.25179/TJEM.2018-59710","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"136 1","pages":"217-224"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86402319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Preoperative Treatment with Plasmapheresis of Patients with Hyperthyroidism","authors":"S. Bahsi, A. Uzay, Nigar Rustemova, F. Onder, O. Celik","doi":"10.25179/tjem.2017-56533","DOIUrl":"https://doi.org/10.25179/tjem.2017-56533","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"13 1","pages":"0-0"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88828238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint Involvement in Patients with Acromegaly and the Association Between Arthropathy and Disease Remission","authors":"Özlem Haliloğlu, Merve Nur Alçiçek, F. Çetinkaya, S. Şahin, Ozge Polat Korkmaz, S. Uğurlu, P. Kadıoğlu","doi":"10.25179/TJEM.20182202-S31","DOIUrl":"https://doi.org/10.25179/TJEM.20182202-S31","url":null,"abstract":"Aim: To evaluate joint complaints, physical examinations and X-rays of acromegalic patients and investigate association between arthropathy and disease remission and effects of arthropathy on quality of life. Method: Acromegalic patients followed at Endocrinology clinic of Cerrahpasa Medical Faculty between 2015-2017 were screened. Demographic and disease status, physical examinations and quality of life scales (Acro-QoL) were recorded. The symptoms and examination findings of patients consulted with Rheumatology or Physical Therapy-Rehabilitation departments and X-rays were evaluated, retrospectively. Results: Ninety-seven patients were assessed, 38 patients (F/M:31/7; p=0.006) had joint complaints and 59 (60.8%; F/M: 40/19; p>0.05) had pathological joint findings. Pathological joint signs were found in 30 patients with no symptoms, whereas 9 out of 38 patients who declared joint symptoms had no signs at rheumatological examination. Patients with symptoms and signs were older (47.6±11.5 vs 53.3±11.9; p=0.02 and 44.3±9.1 vs 53.4±12.3; p<0.001, respectively). When patients were evaluated according to remission status as remission with medical treatment (n=43), remission after surgery(n=27) and active disease (n=18); duration of disease in active disease group was shorter (p=0.01). Other parameters were similar between groups. There was a significant correlation between AcroQoL and shoulder and AcroQoL and small hand joints involvements (p=0.007, r=-0.2 vs p=0.004, r=-0.3), whereas no correlation was found between AcroQoL and knee or elbow involvements. No association found between disease duration and symptoms, examination findings, radiological findings or AcroQoL. Conclusion: Joint degenerative changes detected in 60% of acromegalic patients, and affect quality of life, Regular evaluation of joint symptoms is recommended in the management of acromegalic patients. S-31","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"25 1","pages":"7-7"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79466949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular Adrenal Rest Tumor","authors":"B. Balsak, Z. Pekkolay, Mehmet Güven, A. Tuzcu","doi":"10.25179/tjem.20182202-s19","DOIUrl":"https://doi.org/10.25179/tjem.20182202-s19","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"1 1","pages":"19-19"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80603019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two cases of bullous pemphigoid induced by vildagliptin","authors":"A. Unal, O. Tarçin, G. Demirci, E. Demiralay, A. Mansur, Şemsi Yıldız, N. G. Demirag","doi":"10.25179/TJEM.2017-56526","DOIUrl":"https://doi.org/10.25179/TJEM.2017-56526","url":null,"abstract":"","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"11 2 1","pages":"0-0"},"PeriodicalIF":0.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80627851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}