{"title":"Transanal endoscopic resection of rectal neoplasms","authors":"A. Ilkanich, Y. Voronin, F. Aliev","doi":"10.25789/ymj.2023.81.11","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.11","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"12 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84223607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of COVID-19 on Gognitive change","authors":"R. Mustafin, A. Kazantseva, E. Khusnutdinova","doi":"10.25789/ymj.2023.81.25","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.25","url":null,"abstract":"We hypothesize that cognitive impairment in humans after COVID-19 is due to a change in the epigenetic regulation of brain neurons due to the activation of retroelements under the influence of SARS-CoV-2 virus. In order to confirm the role of transposons in changing the functioning of the brain in patients with COVID-19, the scientific literature and the results of meta-analyses over the past 3 years were studied. As a result, we found that SARS-CoV-2 affects the brain not only through its direct effect, induction of inflammation and coagulopathy, but also through the activation of retroelements, the transcripts of which are processed into microRNAs. This is reflected in changes in the epigenetic regulation of genes in brain neurons, which is reflected in cognitive functions. The mechanisms of integration of the cDNA of SARS-CoV-2 virus into the human genome with the help of retroelement enzymes are described, which is reflected in the development of long-term changes in cognitive functions after COVID-19.","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85439301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. M. Sivtseva, T. M. Klimova, R. Zakharova, E. Ammosova, V. Osakovsky
{"title":"The role of FADS gene polymorphic variants in adaptation to the Northern climatic conditions and metabolic disorders","authors":"T. M. Sivtseva, T. M. Klimova, R. Zakharova, E. Ammosova, V. Osakovsky","doi":"10.25789/ymj.2023.81.26","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.26","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"98 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79834657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intercellular interactions and the level of aggregation of blood cells in the area of inflammation in people living in the European North of Russia","authors":"L. Dobrodeeva, S. N. Balashova, A. Samodova","doi":"10.25789/ymj.2023.81.22","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.22","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"9 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89324042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Savvina, T. Nelunova, T. Burtseva, T. M. Klimova, V. Egorova, V. Chasnyk
{"title":"The role of social factors in the formation of congenital heart disease in the Republic of Sakha (Yakutia)","authors":"M. Savvina, T. Nelunova, T. Burtseva, T. M. Klimova, V. Egorova, V. Chasnyk","doi":"10.25789/ymj.2023.81.27","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.27","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"32 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87946450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sofronova, A. Romanova, V. Nikolaev, M. P. Kirillina
{"title":"The frequency of metabolic syndrome and its components in the non-indigenous population of South Yakutia","authors":"S. Sofronova, A. Romanova, V. Nikolaev, M. P. Kirillina","doi":"10.25789/ymj.2023.81.08","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.08","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"12 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83467329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship of lipid profile and blood pressure in men in the European North of Russia","authors":"L. B. Kim, A. Putyatina","doi":"10.25789/ymj.2023.81.24","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.24","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"2 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75309381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Ushnitsky, T. V. Alekseeva, E. Nikiforova, M. Solovyova, I. Savvina
{"title":"Structural characteristics of dental anomalies in schoolchildren due to the vault height of the hard palate with different degrees of severity of connective tissue dysplasia","authors":"I. Ushnitsky, T. V. Alekseeva, E. Nikiforova, M. Solovyova, I. Savvina","doi":"10.25789/ymj.2023.81.05","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.05","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"16 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76009926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Ishchenko, E. Voropaeva, E. Kazachkova, Yu.V. Khaydukova, E. Kazachkov, T. Shamaeva, D. D. Voropaev, A. Voropaeva, Y. Ishchenko
{"title":"Frequency and outcomes of extremely early preterm birth in pregnant women with new coronavirus infection COVID-19","authors":"L. Ishchenko, E. Voropaeva, E. Kazachkova, Yu.V. Khaydukova, E. Kazachkov, T. Shamaeva, D. D. Voropaev, A. Voropaeva, Y. Ishchenko","doi":"10.25789/ymj.2023.81.20","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.20","url":null,"abstract":"The frequency of extremely early preterm birth (ERPR), their obstetric and perinatal outcomes, morphological features of the placenta in pregnant women in the city of Chelyabinsk and the Chelyabinsk region (CO) with a new coronavirus infection (NCI) in periods 1-2 and 3-4 waves of the COVID pandemic were studied. -19. The results obtained indicate that there is no increase in the frequency of ERPR in pregnant women with NCI. Delivery by caesarean section is associated mainly with the increase in acute respiratory distress syndrome (ARDS) of the mother. In the period of waves 3-4 of the COVID-19 pandemic, an increase in the perinatal mortality rate was noted compared to the period of waves 1-2 without statistical significance of these indicators. At the same time, antenatal fetal death during the 3rd-4th wave of the NCI pandemic was observed statistically significantly more often (p=0.033). The features of placental damage to the placentas in patients with NCI with ERPR and antenatal fetal death during the 3rd-4th wave of the pandemic are severe maternal and fetal vascular malperfusion and severe acute inflammatory lesions of the placenta (2,3 stages and 2,3 degrees).","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"36 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81137149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Prokopiev, S. P. Zorina, M. Vinokurova, O. D. Kondratieva, L. P. Yakovleva
{"title":"Distribution of clinical forms of newly detected pulmonary tuberculosis among adult population of the Sakha Republic (Yakutia) during the pandemic of novel coronavirus infection","authors":"E. Prokopiev, S. P. Zorina, M. Vinokurova, O. D. Kondratieva, L. P. Yakovleva","doi":"10.25789/ymj.2023.81.17","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.17","url":null,"abstract":"The article analyzes the epidemic situation of tuberculosis and the clinical structure of newly diagnosed pulmonary tuberculosis among the adult population, both in general on the territory of the Republic of Sakha (Yakutia) and with the allocation of the Arctic zone during the period of restrictive measures organized to combat the pandemic of a new coronavirus infection COVID- 19. During the period of strengthening anti-epidemic and sanitary measures, there was a significant decrease in the main epidemic indicators for tuberculosis, but at the same time, the situation with the timely detection of tuberculosis among the population worsened. The proportion of newly diagnosed adult patients with destructive forms of pulmonary tuberculosis and bacterial excretion increased when self-referencing to medical organizations. A statistically significant correlation was found between the indicators of the volume and quality of preventive examinations of the population for tuberculosis and the aggravated clinical structure of newly diagnosed patients with tuberculosis.","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"21 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84058311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}