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Comments on difficult questions in the JSHI certification paper test 2018 2018年JSHI认证纸考试题点评
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/MHC.24.101
A. Kimura
{"title":"Comments on difficult questions in the JSHI certification paper test 2018","authors":"A. Kimura","doi":"10.12667/MHC.24.101","DOIUrl":"https://doi.org/10.12667/MHC.24.101","url":null,"abstract":"Japanese Society for Histocompatibility and Immunogenetics (JSHI) has a certification system for HLA technologist and Director for Histocompatibility testing, in which ability and knowledge about the Histocompatibility and Immunogenetics is required. To evaluate the ability and knowledge, a paper examination is obliged. Here I will comment on several questions of which percentage of correct answer was below 40% in the last year 2018.","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124248076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of cat MHC genes and application for veterinary medicine field 猫MHC基因的特征及其在兽医学领域的应用
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.26.204
Masaharu Okano, T. Moritomo, T. Shiina
{"title":"Characteristics of cat MHC genes and application for veterinary medicine field","authors":"Masaharu Okano, T. Moritomo, T. Shiina","doi":"10.12667/mhc.26.204","DOIUrl":"https://doi.org/10.12667/mhc.26.204","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125787397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-human MHC genotyping methods using next generation sequencing 使用下一代测序的非人类MHC基因分型方法
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/MHC.26.115
Kousuke Tanimoto, T. Naruse, A. Kimura
{"title":"Non-human MHC genotyping methods using next generation sequencing","authors":"Kousuke Tanimoto, T. Naruse, A. Kimura","doi":"10.12667/MHC.26.115","DOIUrl":"https://doi.org/10.12667/MHC.26.115","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121488154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Population specific positive selection acted on the HLA class II region in Papuans 人群特异性阳性选择作用于巴布亚人HLA II类区域
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.27.53
Mariko Isshiki, J. Ohashi
{"title":"Population specific positive selection acted on the HLA class II region in Papuans","authors":"Mariko Isshiki, J. Ohashi","doi":"10.12667/mhc.27.53","DOIUrl":"https://doi.org/10.12667/mhc.27.53","url":null,"abstract":"The first colonization into Oceania occurred about 47 thousand years ago. Modern Papuans are the descendants of the first immigrants and considered to have adapted to Oceanian environment over the years. The Human Leukocyte Antigen ( HLA ) plays an important role in acquired immunity and has been reported to have undergone natural selection in human populations. In this study, we examined whether natural selection has acted on the HLA region in modern Papuan genomes. We estimated integrated Haplotype Score (iHS) across the chromosome 6 and detected a signal of a strong positive selection acted on HLA class II region. A high linkage disequilibrium between a SNP with the strongest signal (rs200439840) and haplotype DRB1*15:01-DQA1*01:02-DQB1*06:02 was observed. The haplotype DRB1*15:01-DQB1*06:02 was commonly observed in Melanesia populations. Our results indicate that this haplotype was adaptive to Oceanian environment and increased by positive selection.","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130478883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Overview of HLA DNA typing technology HLA DNA分型技术综述
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.28.83
F. Azuma
{"title":"Overview of HLA DNA typing technology","authors":"F. Azuma","doi":"10.12667/mhc.28.83","DOIUrl":"https://doi.org/10.12667/mhc.28.83","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131737898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood tests for transplant and blood transfusion; Excluding HLA testing 为移植和输血进行血液检查;排除HLA检测
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.29.111
Koki Fujiwara
{"title":"Blood tests for transplant and blood transfusion; Excluding HLA testing","authors":"Koki Fujiwara","doi":"10.12667/mhc.29.111","DOIUrl":"https://doi.org/10.12667/mhc.29.111","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125991644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A haplotype of Toll-like receptor 1 is associated with resistance to Buerger disease in Japanese toll样受体1的单倍型与日本人对伯格病的抗性有关
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.26.189
Shinya Koizumi, T. Naruse, A. Kimura
{"title":"A haplotype of Toll-like receptor 1 is associated with resistance to Buerger disease in Japanese","authors":"Shinya Koizumi, T. Naruse, A. Kimura","doi":"10.12667/mhc.26.189","DOIUrl":"https://doi.org/10.12667/mhc.26.189","url":null,"abstract":"Buerger disease (BD) is a vascular disease of unknown etiology characterized by thrombotic occlusion of peripheral arteries. Smoking is a well-known risk factor of BD, but genetic factors may also play an etiological role. Because chronic infection such as oral periodontitis is suggested to be involved in the pathogenesis of BD, polymorphisms in genes responsible for infectious immunity might be associated with BD as genetic factors. In this study, 87 patients and 312 healthy controls were investigated for 26 polymorphisms in the genes for Toll-like receptor (TLR). It was found that single nucleotide polymorphism (SNP) rs5743599 (G>A) in TLR1 showed a nominal association, where the A allele frequency was increased in the patients (0.200 in the patients vs. 0.133 in the controls, odds ratio (OR)=1.63, 95% confidence interval (95%CI)=1.01– 2.62, p=0.042). When the GG genotype was taken as a reference, the GA genotype conferred significantly high risk (OR=1.81, 95%CI=1.03–3.17, p=0.038). In addition, haplotype analysis of TLR1 locus showed that the frequency of a haplotype containing the G allele of rs5743599 was significantly decreased in the patients (0.003 in the patients vs. 0.028 in the controls, OR=0.10, 95%CI=0.01–0.99, permutation p=0.048), suggesting a TLR1 haplotype-linked genetic factor in association with BD. These findings implied that the pathogenesis of BD was at least in part controlled by the innate immunity via TLR10/ TLR1 locus.","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130808295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comments in the JSHI certification paper test 2022 JSHI认证试卷测试2022中的评论
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.29.98
Taeko K Naruse
{"title":"Comments in the JSHI certification paper test 2022","authors":"Taeko K Naruse","doi":"10.12667/mhc.29.98","DOIUrl":"https://doi.org/10.12667/mhc.29.98","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131190535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gene structure, expression and polymorphism of the HLA-G locus HLA-G位点的基因结构、表达和多态性
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.28.102
Shingo Suzuki, Y. Kametani, T. Shiina
{"title":"Gene structure, expression and polymorphism of the HLA-G locus","authors":"Shingo Suzuki, Y. Kametani, T. Shiina","doi":"10.12667/mhc.28.102","DOIUrl":"https://doi.org/10.12667/mhc.28.102","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132407844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of BoLA-DRB3 with bovine leukemia virus BoLA-DRB3与牛白血病病毒的关系
Major Histocompatibility Complex Pub Date : 1900-01-01 DOI: 10.12667/mhc.29.158
Chieh-Wen Lo, Y. Aida
{"title":"Association of BoLA-DRB3 with bovine leukemia virus","authors":"Chieh-Wen Lo, Y. Aida","doi":"10.12667/mhc.29.158","DOIUrl":"https://doi.org/10.12667/mhc.29.158","url":null,"abstract":"","PeriodicalId":426753,"journal":{"name":"Major Histocompatibility Complex","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131177342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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