APOS Trends in Orthodontics最新文献

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Effect of leukocyte platelet-rich fibrin on the rate of canine movement – A prospective and randomized control trial 富血小板白细胞纤维蛋白对犬运动速率的影响——一项前瞻性随机对照试验
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-06-13 DOI: 10.25259/apos_42_2023
Seema Gupta, Eenal Bhambri, Monika Sorokhaibam, Namit Nagar, Deepali Agarwal, M. Sharma
{"title":"Effect of leukocyte platelet-rich fibrin on the rate of canine movement – A prospective and randomized control trial","authors":"Seema Gupta, Eenal Bhambri, Monika Sorokhaibam, Namit Nagar, Deepali Agarwal, M. Sharma","doi":"10.25259/apos_42_2023","DOIUrl":"https://doi.org/10.25259/apos_42_2023","url":null,"abstract":"\u0000\u0000The present study was conducted to investigate the effects of leukocyte and platelet-rich fibrin (L-PRF) on the rate of maxillary canine retraction for a period of 5 months.\u0000\u0000\u0000\u0000A split-mouth study was conducted on 16 patients (32 extraction sockets) (Nine males and seven females; age ranging 17–25 years) with Class II Div 1 malocclusion or Class I bimaxillary protrusion, requiring therapeutic extraction of bilateral maxillary first premolars. After the initial leveling and alignment, L-PRF plugs were placed immediately in the randomly selected socket (Experimental Group) and the other side served as control for secondary healing (Control Group). This was followed by the activation of nickel-titanium closed coil springs for canine retraction. The rate of canine movement, canine rotation, tipping, root resorption, and molar movement was assessed at monthly intervals for 5 months (T0–T5). Data were collected from study models. Assessment of pain accompanying the procedure was done using a Likert scale. The trial was registered at the Clinical Trials Registry of India (REF/2022/02/051837).\u0000\u0000\u0000\u0000The study revealed that there was a significant increase in the rate of canine movement on the experimental side in the first 2 months and significant molar anchorage loss was seen only in the 1st month. There were statistically non-significant differences in canine rotation, tipping, probing depth, root resorption, and pain perception between the groups.\u0000\u0000\u0000\u0000The use of L-PRF plugs in the extraction sockets enhanced the rate of canine movement in the first 2 months of treatment with less anchorage loss and no deleterious effects on periodontium.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"35 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81260653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is the most effective technique and composite for bonding aligner attachments to primary enamel? 什么是最有效的技术和复合材料粘合牙釉质对准器附着物?
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-06-13 DOI: 10.25259/apos_57_2023
S. Çokakoğlu, R. Nalçacı, Murat Tozlu, S. Altıntaş
{"title":"What is the most effective technique and composite for bonding aligner attachments to primary enamel?","authors":"S. Çokakoğlu, R. Nalçacı, Murat Tozlu, S. Altıntaş","doi":"10.25259/apos_57_2023","DOIUrl":"https://doi.org/10.25259/apos_57_2023","url":null,"abstract":"\u0000\u0000This in vitro study evaluated the shear bond strength (SBS) of aligner attachments bonded to primary teeth with different techniques and composites.\u0000\u0000\u0000\u0000Eighty attachments were prepared using five composites: An aligner composite (GC aligner connect [GAC]), two flowable restorative composites (G-aenial universal injectable and Estelite universal super low flow), and two one-step orthodontic composites integrated with primer (GC ortho connect flow and GC ortho connect). Aligner and restorative composites were applied with self- or total-etch (SE or TE) modes of universal adhesive (G-Premio Bond). Self-adhering composites integrated with primer were applied after acid etching. Excessive composites were removed with tungsten carbide burs after the polymerization of resin attachments. All primary teeth were exposed to thermocycling. Bond strength was determined with a universal testing machine. Remnant resin attachment was scored with the resin attachment remnant index. Kruskal–Wallis, Mann–Whitney, and Chi-square tests were used for statistical analyses.\u0000\u0000\u0000\u0000The self-etching technique demonstrated lower SBS values compared to total-etching and self-adhering groups regardless of composite type. The highest SBS was found with aligner composite (GAC) and the total-etching technique. Self-adhering composites showed sufficiently high SBS values comparable with GAC and TE bonding techniques. The amount of remnant attachment was significantly higher in the total-etching and self-adhering groups compared to SE bonding with GAC (P < 0.05).\u0000\u0000\u0000\u0000Self-adhering orthodontic composites can be preferred to simplify the bonding of aligner attachments to primary enamel after acid etching.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"203 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77016349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of TGFB3 and FGFs gene polymorphisms with cleft lip with or without cleft palate a systematic review TGFB3和FGFs基因多态性与唇裂伴或不伴腭裂的相关性:系统综述
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-20 DOI: 10.25259/apos_198_2022
Andrea Soledad Quizhpi-Quito, Ebingen Villavicencio Caparó, Diego Maurício Bravo-Calderón
{"title":"Association of TGFB3 and FGFs gene polymorphisms with cleft lip with or without cleft palate a systematic review","authors":"Andrea Soledad Quizhpi-Quito, Ebingen Villavicencio Caparó, Diego Maurício Bravo-Calderón","doi":"10.25259/apos_198_2022","DOIUrl":"https://doi.org/10.25259/apos_198_2022","url":null,"abstract":"\u0000\u0000The objective of this study was to conduct a systematic review of the possible association between transforming growth factor B3 (TGFB3) and fibroblast growth factors (FGFs) gene polymorphisms and nonsyndromic cleft lip with or without cleft palate (NSCL/P).\u0000\u0000\u0000\u0000Two reviewers independently screened studies by examining all titles and abstracts. Studies were included if they met the following criteria: The outcome of interest was NSCL/P; the polymorphisms studied were TGFB3 and FGF; they presented sufficient data, that is, allele/genotype frequency between cases and controls; or their odds ratio with 95% confidence interval. Study quality was independently assessed by a risk of bias assessment for genetic association studies.\u0000\u0000\u0000\u0000Based on the inclusion criteria, we have selected a total of six articles (four for TGFB and two for FGF). Particularly for the TGFB gene, we have found significant results in exon 4 in the variant g.15812T>G, and in the single-nucleotide polymorphisms rs2300607 A/T, in the distribution between cases and controls. On the other hand, for the FGF gene, we observed a statistically significant in the genotype rs34010 CA.\u0000\u0000\u0000\u0000None of the genetic variations that show the association is verified in different populations; therefore, there is not enough scientific validation regarding the association between TGFB and FGF polymorphism and NSCL/P. The findings of the different studies suggest the need for further investigations with samples composed of a larger number of individuals in different populations, which should be performed with all the standards for genetic studies, thus allowing an understanding of the molecular basis of the disease.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"8 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84037365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of alignment efficacy and arch dimensions changes with superelastic-, heat-activated-, and seven stranded coaxial nickel-titanium archwires during fixed orthodontic treatment – A double-blind randomized clinical trial 超弹性、热激活和七股同轴镍钛弓线在固定正畸治疗期间对准效果和弓尺寸变化的比较——一项双盲随机临床试验
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-20 DOI: 10.25259/apos_44_2023
Shivani Sharma, S. Verma, Vinay Kumar, R. Verma, S. Singh
{"title":"Comparison of alignment efficacy and arch dimensions changes with superelastic-, heat-activated-, and seven stranded coaxial nickel-titanium archwires during fixed orthodontic treatment – A double-blind randomized clinical trial","authors":"Shivani Sharma, S. Verma, Vinay Kumar, R. Verma, S. Singh","doi":"10.25259/apos_44_2023","DOIUrl":"https://doi.org/10.25259/apos_44_2023","url":null,"abstract":"\u0000\u0000The objectives of this study were to compare the alignment efficacy, changes in arch dimensions, and pain experience with three different nickel-titanium (NiTi) archwires.\u0000\u0000\u0000\u0000Forty-five subjects were subjected to indirect bonding in the mandibular arch, and allocated to three groups using block randomization; Group 1 (0.014” Superelastic NiTi), Group 2 (0.014” 27° Copper NiTi), and Group 3 (0.016” seven stranded coaxial NiTi archwire). The mandibular study models were retrieved periodically at 4-week intervals for 12 weeks, which were blinded to measure the change in Little’s irregularity index (LII) and dental arch dimensions. Pain and discomfort were recorded with visual analog scale at five different time intervals, namely, immediately after bonding (0) and at 1-, 4-, 8-, and 12-h for initial 7 days. Repeated analysis of variance, Wilcoxon Signed-Rank test, post hoc Bonferroni test, and Friedman’s test was applied for the comparison and was used for data analysis.\u0000\u0000\u0000\u0000A significant reduction of LII score and increase inarch length, intercanine, interpremolar, and intermolar width (P ≤ 0.001) were observed after 12 weeks among all groups. However, intergroup comparison showed significant mean changes only for intercanine width (Group 1 versus 3) and interpremolar width (Groups 1 and 3; Groups 2 and 3). All other variables were found to be insignificant at all-time intervals when compared among each group. The increase in pain score was maximum with Group 1and least with Group 3.\u0000\u0000\u0000\u0000All archwires were found to be effective in reducing the LII score. Nevertheless, Group 3 archwire could achieve reduction of LII to zero in 14% of subjects than Groups 1 and 2.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"22 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81181890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cephalometric evaluation of posterior airway space in Chinese and Egyptian races 中国和埃及人种后气道空间的头颅测量评价
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-12 DOI: 10.25259/apos_17_2023
Abdel-rahman Mohamed, Yaosen Chen, Khaled Wafaie, Maher Al-balaa, Bayan M. Abusafia, O. M. Mohammed, Yan Yang, Yiqiang Qiao
{"title":"Cephalometric evaluation of posterior airway space in Chinese and Egyptian races","authors":"Abdel-rahman Mohamed, Yaosen Chen, Khaled Wafaie, Maher Al-balaa, Bayan M. Abusafia, O. M. Mohammed, Yan Yang, Yiqiang Qiao","doi":"10.25259/apos_17_2023","DOIUrl":"https://doi.org/10.25259/apos_17_2023","url":null,"abstract":"\u0000\u0000The aim of this study was to evaluate the size of posterior airway space (PAS) and hyoid bone position in Chinese and Egyptian races in both genders using cephalometry.\u0000\u0000\u0000\u0000Lateral Cephalometric X-ray were collected from 195 healthy young adults (96 Chinese subjects and 99 Egyptian subjects). Twenty cephalometric measurements (linear and angular) of the nasopharynx, oropharynx, hypopharynx, tongue, and hyoid bone were recorded. Considering gender, according to the ANB angle, the subjects were classified into three types of skeletal malocclusion: class I (1° ≤ ANB ≤ 3°), class II (ANB > 3°), and class III (ANB < 1°). Probability (P) ≤ 0.05 was considered statistically significant. Confident intervals of 95% were used and P < 0.05 was considered to represent statistically significant differences.\u0000\u0000\u0000\u0000Significant differences were founded in (PNS-V) (P ≤ 0.01), (TT-V) (P ≤ 0.05), ([Hy-Me-MP] [P ≤ 0.01] [Hyoid–MP-Prep] [P ≤ 0.05] [Hy-C3] [P ≤ 0.01] and [Hy-S] [P ≤ 0.05]), and (PNS-U) between Class II and Class III (P ≤ 0.05) in Chinese group. Significant differences were founded in (TT_FH) (P < 0.001), (Hy_RGn) (P < 0.001), Hyoid bone and C3 (Hy_C3) (P < 0.05), (DeepPharyxatPog) (P < 0.05), and (Hy_C3) between Class I and Class II (P < 0.05) in Egyptian group.\u0000\u0000\u0000\u0000There is no direct clinical implication of this study. However, the study shows a reference of the average size of PAS in both genders of Egyptian and Chinese races. Gender showed a significant influence on the PAS dimensions in both Chinese and Egyptian individuals. Sexual dimorphism may account for larger airway dimensions and hyoid bone geometry in both Chinese and Egyptian males.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"31 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81124090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of an adult patient with severe crowding using lingual appliances and mini-screw anchorage: A case report 使用舌部矫治器和微型螺钉固定治疗严重拥挤的成人患者1例报告
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-12 DOI: 10.25259/apos_46_2023
T. M. Son, V. Ngoc, Nguyen Viet Anh
{"title":"Management of an adult patient with severe crowding using lingual appliances and mini-screw anchorage: A case report","authors":"T. M. Son, V. Ngoc, Nguyen Viet Anh","doi":"10.25259/apos_46_2023","DOIUrl":"https://doi.org/10.25259/apos_46_2023","url":null,"abstract":"At present, more adult patients seek orthodontic treatment so orthodontists are more likely to face periodontal patients and esthetic appliance demand increases. This case report presents the management of an adult patient with mild periodontitis and severe crowding using lingual appliances and mini-screw anchorage. Interproximal stripping was performed to create space and correct the triangular tooth shape and gingival black triangles. Four mini-screws were implanted in the palatal alveolar bone and mandibular buccal shelf to distalize the entire upper and lower arch. According to the case report, interproximal stripping in combination with mini-screw-assisted entire arch distalization and lingual appliances may be an effective space-creation approach in patients treated with non-extraction way.","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"66 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81133425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closure of first molar extraction spaces and correction of Class II malocclusion using anterior bite turbo and Class II elastics: A case report 第一磨牙拔牙间隙封闭及II类牙合矫治1例
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-12 DOI: 10.25259/apos_54_2023
Nguyen Viet Anh, V. Ngoc, T. M. Son
{"title":"Closure of first molar extraction spaces and correction of Class II malocclusion using anterior bite turbo and Class II elastics: A case report","authors":"Nguyen Viet Anh, V. Ngoc, T. M. Son","doi":"10.25259/apos_54_2023","DOIUrl":"https://doi.org/10.25259/apos_54_2023","url":null,"abstract":"At present, orthodontists are treating more adult patients with missing or hopeless first molars as these teeth have the highest incidence of decay in permanent dentition. This case report presented the closure of extraction spaces of four first molars in a patient with Class II malocclusion. High torque self-ligating brackets were used combined with anterior bite turbo and Class II elastics. According to the case report, the combination of anterior bite turbo and Class II elastics may have the possibility to correct bite deepening during space closure and allow further upper incisor retraction and Class II correction.","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"46 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76044089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporomandibular joint and skeletal changes in response to Twin block and Advansync appliance therapy – A three dimensional study Twin block和Advansync矫治器治疗后颞下颌关节和骨骼的变化-一项三维研究
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-12 DOI: 10.25259/apos_39_2023
S. Arumugam, Haritha Pottipalli Sathyanarayana, S. Padmanabhan
{"title":"Temporomandibular joint and skeletal changes in response to Twin block and Advansync appliance therapy – A three dimensional study","authors":"S. Arumugam, Haritha Pottipalli Sathyanarayana, S. Padmanabhan","doi":"10.25259/apos_39_2023","DOIUrl":"https://doi.org/10.25259/apos_39_2023","url":null,"abstract":"\u0000\u0000This study aimed to analyze and compare the temporomandibular joint (TMJ) and skeletal changes three dimensionally in growing patients with Class II malocclusion treated with the Twin block (TB) and Advansync appliance.\u0000\u0000\u0000\u0000This prospective study included 20 patients with Class II Division 1 malocclusion of which ten patients comprised the TB group and ten patients the Advansync group. Cone-beam computed tomographs were taken before treatment, and at the end of the functional phase (6–8 months). The condyle, glenoid fossa, and skeletal changes were assessed in all the three planes and the measurements were made using CARESTREAM software.\u0000\u0000\u0000\u0000The TB group demonstrated a significant increase in the condylar dimensions, superior joint space, mandibular length (P = 0.005), and decrease in anterior joint space (P = 0.001) in response to treatment and the Advansync group showed a significant increase in the condylar dimensions, mandibular length, and a significant restriction in the maxillary length. Comparison between the two groups showed a significant increase in the fossa depth in the TB group and restriction in the maxillary growth in the Advansync group.\u0000\u0000\u0000\u0000TB and Advansync group showed TMJ and skeletal changes. However, the Advansync showed more headgear effect but less glenoid fossa changes compared to the TB group.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"28 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89378649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the accuracy and precision of digital model transfer methods used in virtual orthognathic planning 比较了虚拟正交规划中数字模型转换方法的精度和精度
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-05-12 DOI: 10.25259/apos_25_2023
Ceylan Güzel, A. Özel, Mantas Vaitiekūnas, S. Grybauskas, S. Uçkan
{"title":"Comparing the accuracy and precision of digital model transfer methods used in virtual orthognathic planning","authors":"Ceylan Güzel, A. Özel, Mantas Vaitiekūnas, S. Grybauskas, S. Uçkan","doi":"10.25259/apos_25_2023","DOIUrl":"https://doi.org/10.25259/apos_25_2023","url":null,"abstract":"\u0000\u0000The hard and soft tissues of the head and neck, dentition, and temporomandibular joint are the determining elements in orthognathic surgery planning. The accuracy and precision of the relationship between the jaws at the beginning of treatment and their final position depend on an accurate dentition record. The aim of this study was to determine the simplest and most feasible virtual dental model transfer method for three-dimensional orthognathic planning according to clinical applicability, technical difficulty, effective costs, accuracy, and precision.\u0000\u0000\u0000\u0000A total of ten spherical porcelain markers were placed in plaster models of the maxilla and mandible of a patient. The models were scanned using an intraoral optical scanner, an extraoral digital model scanner, and cone-beam computerized tomography. To evaluate reliability, each measurement was repeated 10 times at 1-week intervals and the distances between points were measured horizontally and vertically. The findings obtained in the study were evaluated statistically using IBM SPSS Statistics 2.2 program.\u0000\u0000\u0000\u0000Measurements obtained with the extraoral model scanner did not differ from the digital caliper method (P > 0.05), while there were significant differences between the digital caliper and the other methods (intraoral 3D scanner P = 0.000; CBCT P = 0.001).\u0000\u0000\u0000\u0000Although all of the measurements showed high consistency among all methods, the most accurate results were obtained with the extraoral digital model scanner. (r = 0.99, P = 0.01, P < 0.05).\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"19 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85078326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum osteocalcin – A biochemical marker for pubertal growth assessment 血清骨钙素-青春期生长评估的生化标志物
IF 0.4
APOS Trends in Orthodontics Pub Date : 2023-04-19 DOI: 10.25259/apos_20_2023
A. Yezdani, K. Kumar, K. Padmavathy
{"title":"Serum osteocalcin – A biochemical marker for pubertal growth assessment","authors":"A. Yezdani, K. Kumar, K. Padmavathy","doi":"10.25259/apos_20_2023","DOIUrl":"https://doi.org/10.25259/apos_20_2023","url":null,"abstract":"\u0000\u0000Growth evaluation methods have made great strides in the shift from radiologic to non-radiologic biomarkers. Osteocalcin (OC), a bone protein, has been reportedly used as a biomarker for osteoblastic bone formation. The present study aimed at evaluation of serum OC in Class II skeletal patterns for accurate assessment of pubertal growth spurt to facilitate functional jaw orthopedics during the growth period.\u0000\u0000\u0000\u0000Eighty subjects, comprising 38 males and 42 females with skeletal Class II malocclusion in the age range of 11–18 years, were recruited for the study. Human serum OC was quantitatively assessed with enzyme-linked immunosorbent assay. The cervical vertebral stages were assessed from lateral cephalograms. Statistical analysis for gender-wise comparison of mean serum levels of OC at each cervical stage (CS) and in the intervals of the CSs was carried out using Kruskal–Wallis test and for intergroup comparisons, Mann–Whitney U-test with Bonferroni’s correction was done.\u0000\u0000\u0000\u0000Gender-wise comparison of mean serum OC levels revealed that it was highest in CS2 in both males (72.24 ng/mL) and females (74.71 ng/mL) with another discernible peak in CS5 in males (66.82 ng/mL) and in CS6 in females (63.78 ng/mL), exhibiting thereby a circadian rhythm in bone modeling during the entire adolescent growth spurt.\u0000\u0000\u0000\u0000Despite a pre-pubertal and a late pubertal spike in both the genders, the mean OC serum levels actually exhibited a circadian rhythmicity across all the CSs, exhorting thereby the importance of bone remodeling during the complete circumpubertal growth period.\u0000","PeriodicalId":42593,"journal":{"name":"APOS Trends in Orthodontics","volume":"34 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82060514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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