Hypertension Research in Pregnancy最新文献_第8页

A minimally invasive hemostatic strategy in obstetrics aiming to preserve uterine function and enhance the safety of subsequent pregnancies 微创止血策略在产科旨在保护子宫功能和提高后续妊娠的安全性

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2018-013

S. Takeda, J. Takeda, S. Makino

{"title":"A minimally invasive hemostatic strategy in obstetrics aiming to preserve uterine function and enhance the safety of subsequent pregnancies","authors":"S. Takeda, J. Takeda, S. Makino","doi":"10.14390/JSSHP.HRP2018-013","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-013","url":null,"abstract":"Numerous trial-and-error approaches have been taken to achieve effective hemostasis for difficult obstetrical uterine hemorrhage cases. In the field of obstetrics, transcatheter arterial embolization (TAE) is known to be highly effective for controlling uterine hemorrhage and hematoma. This procedure achieves a high hemostasis rate, and the frequency of hysterectomy has thus sharply decreased. Although arterial ligation for massive hemorrhage at the time of cesarean section may fail to control bleeding in a number of cases due to an abundance of collateral circulation pathways, various new hemostatic techniques such as compression sutures of the uterus, uterine tamponade with gauze or a balloon, and intraoperative TAE have become available. However, complications including subsequent endometrial hypoplasia, menstruation disorder, infertility, pregnancy loss, placenta accreta, and uterine rupture have been reported even in cases undergoing successful hemostasis with TAE using absorbable embolus. Against this backdrop, we reconsidered fertility-preserving hemostatic strategies for critical obstetrical hemorrhage under these circumstances, and herein discuss how to select the optimal strategy based on our knowledge of and experience with various hemostatic procedures.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2018-013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43962552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Congress President 国会主席

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Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.1093/acprof:oso/9780195647518.003.0019

B. Nanda

引用次数: 0

Critical appraisal of the role of applying uterine fundal pressure in labour: First, do no harm 对分娩中应用宫底压力作用的批判性评价：首先，不要造成伤害

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2019-007

K. Papadakis

{"title":"Critical appraisal of the role of applying uterine fundal pressure in labour: First, do no harm","authors":"K. Papadakis","doi":"10.14390/JSSHP.HRP2019-007","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2019-007","url":null,"abstract":"Aim: Fundal pressure during labour is a frequently used manoeuvre for expediting delivery in cases of fetal distress, dystocia and maternal exhaustion. It is often underreported and therefore challenging to accurately estimate its prevalence. It remains a highly controversial topic, having been abandoned in many countries due to its potentially harmful consequences. Still, some health care professionals consider it safe and effective in life-threatening obstetric emergencies. Our objective was to evaluate the evidence behind the merits and drawbacks of its implementation into clinical practice. Methods: This is a critical review based on utilising high-quality references on whether it is justifiable to insist on using fundal pressure in contemporary obstetrics. Results: Fundal pressure is understudied with significant variations worldwide. Reports documenting of any substantial benefit are sparse in the literature. Nevertheless, there is a clear association with various adverse outcomes. An increasing number of experts suggest that fundal pressure should be relinquished. Conclusions: Unless future randomised controlled trials change our views on traditional methods for shortening labour when needed, practitioners should be extra vigilant in avoiding dubious techniques, as deviation from national guidelines could jeopardise aspirations for optimal intrapartum care. In the time being, fundal pressure should be limited for research purposes only within well-designed studies.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":"2013 36","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41331727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New definition and classification of “Hypertensive Disorders of Pregnancy (HDP) 妊娠期高血压疾病(HDP)的新定义及分类

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/jsshp.hrp2019-010

S. Makino, J. Takeda, S. Takeda, Kazushi Watanabe, K. Matsubara, O. Nakamoto, J. Ushijima, A. Ohkuchi, K. Koide, K. Mimura, M. Morikawa, K. Naruse, Kanji Tanaka, T. Nohira, H. Metoki, I. Kawabata, K. Takagi, M. Yamasaki, A. Ichihara, T. Kimura, S. Saito, H. Seki

引用次数: 8

Development of new therapeutic agents for preterm birth by glycosaminoglycan chain remodeling of urinary trypsin inhibitor 尿胰蛋白酶抑制剂糖胺聚糖链重构治疗早产新药的研制

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2018-011

Seigo Tanaka, I. Kakizaki, Kanji Tanaka, T. Kodama, Asami Ito-Fukuyama, S. Suto, R. Takahashi, Y. Yokoyama

{"title":"Development of new therapeutic agents for preterm birth by glycosaminoglycan chain remodeling of urinary trypsin inhibitor","authors":"Seigo Tanaka, I. Kakizaki, Kanji Tanaka, T. Kodama, Asami Ito-Fukuyama, S. Suto, R. Takahashi, Y. Yokoyama","doi":"10.14390/JSSHP.HRP2018-011","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-011","url":null,"abstract":"Aim: This study aimed to examine the effects of the glycosaminoglycan (GAG) chain in urinary trypsin inhibitor (UTI) on uterine cervical fibroblasts (UCFs) and to apply the findings to the development of more effective therapeutic drugs for the management of preterm birth. Methods: We prepared GAG chain-remodeled UTIs by hydrolysis and/or transglycosylation by testicular hyaluronidase. These UTIs were added to UCFs obtained from gynecology operations, and the effects of UTIs on the release of IL-8, IL-6, MMP-8, and MMP-9 were examined. Results: UTIs that were not hydrolyzed tended to reduce IL-8 release more strongly than GAG chain-hydrolyzed UTIs. IL-6 was not affected by GAG chain hydrolysis of UTIs. GAG chain-hydrolyzed UTIs tended to reduce MMP-8 and MMP-9 release more strongly than non-hydrolyzed UTIs. Conclusions: Our findings suggest that the GAG chain of UTI might reduce hyaluronan during cervical ripening by reducing IL-8 release and has opposite effects on reducing MMP-8 and MMP-9 release related to collagen degradation. This insight may be helpful in the development of more effective therapeutic drugs for the management of preterm birth.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2018-011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41344139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Impaired endometrial function and unexplained recurrent pregnancy loss 子宫内膜功能受损和原因不明的复发性妊娠丢失

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2018-012

K. Kuroda

引用次数: 9

Video image: Ultrasound findings of a novel subtype of atonic postpartum hemorrhage: is it still a diagnosis of exclusion? 视频图像：一种新型亚型无张力产后出血的超声检查结果：它仍然是排除性诊断吗？

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2019-001

E. Kondoh, Yoshitsugu Chigusa, Akihiko Ueda, Baku Nakakita, Haruta Mogami, M. Mandai

引用次数: 3

Peripartum asymptomatic cerebral hemorrhage (PEACH) 围产期无症状脑出血（PEACH）

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Hypertension Research in Pregnancy Pub Date : 2019-03-30 DOI: 10.14390/JSSHP.HRP2019-002

Y. Kubota, Yoshie Shibata, Shunji Suzuki

引用次数: 0

Committee for Academic Affairs JSSHP Research Award 2018 Basic Research Establishment of advanced maternal age model mice: novel biomarker profiles in advanced maternal age with hypertensive disorders of pregnancy 学术委员会JSSHP研究奖2018高龄产妇模型小鼠基础研究建立：妊娠期高血压疾病高龄产妇的新生物标志物图谱

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Hypertension Research in Pregnancy Pub Date : 2018-11-30 DOI: 10.14390/JSSHP.6.39

K. Furuya, K. Kumasawa, H. Nakamura, T. Kimura

引用次数: 0

The 7th Committee Meeting of Pregnancy Associated Stroke Proceedings 妊娠相关脑卒中会议记录第7次委员会会议

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Hypertension Research in Pregnancy Pub Date : 2018-11-30 DOI: 10.14390/jsshp.6.41

引用次数: 0