Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine最新文献

{"title":"Saliva and its value as a diagnostic material","authors":"Magdalena Potempa-Jeziorowska, Paweł Jonczyk, E. Świętochowska, M. Kucharzewski","doi":"10.15557/pimr.2022.0005","DOIUrl":"https://doi.org/10.15557/pimr.2022.0005","url":null,"abstract":"In recent years, because of huge advances in medicine and technological progress, coupled with the application of increasingly accurate diagnostic tests, the use of saliva for medical purposes has become increasingly important. Saliva is a natural digestive secretion of the major and minor salivary glands that ensures, among other things, the proper functioning of the occlusion system. Other functions include the protection of dental surfaces from various external influences, and involvement in the formation of the food bolus and in the acts of swallowing, digestion, and speech. The composition of saliva is varied. In addition to water, which is found in saliva in far greater quantities than in any other substance, it also contains various substances which are also present in the blood. Their determination in saliva often has a great diagnostic potential in the early detection of both oral and systemic diseases. The diagnosis of selected systemic diseases using saliva is becoming the subject of a growing number of scientific studies. In this paper, the authors have focused on providing the reader with basic information about the physiology of saliva and on presenting the possibilities for its diagnostic application in selected systemic diseases.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42143792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicella with secondary skin bacterial complications: case reports","authors":"L. Levytska, I. Nezgoda","doi":"10.15557/pimr.2022.0013","DOIUrl":"https://doi.org/10.15557/pimr.2022.0013","url":null,"abstract":"Chickenpox is a very contagious childhood disease with a self-limited course. It is most common in children up to 10 years old, but can infect a person at any age. Varicella presents with itchy pseudo-polymorphic rash (macula, papula, vesicle, crust) and mild intoxication syndrome. The disease is benign and uncomplicated in general, but complications can occur regardless of immune status and concomitant diseases. Neurological and respiratory are among the most common complications. In the patients described in this article, we can observe secondary bacterial superinfection (pyoderma and phlegmon). These are the third most common complications of varicella, and may have serious consequences. These cases are presented to call attention to proper skincare in a patient with chickenpox and to the choice of an appropriate antipyretic to control fever. It is also important to emphasise the importance of vaccination against this disease and to combat the misconceptions of anti-vaxxers.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44989360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intramuscular haemangioma in a child","authors":"Izzah Akashah, J. Saniasiaya","doi":"10.15557/pimr.2022.0014","DOIUrl":"https://doi.org/10.15557/pimr.2022.0014","url":null,"abstract":"Aim of the study: To outline the challenge faced in diagnosing intramuscular haemangioma of the masseter in a child. Intramuscular haemangioma is an unusual type of haemangioma and is oftentimes overlooked or misdiagnosed by health care professionals. Case report: Herein, we discuss a complex case of a 9-year-old girl referred to otorhinolaryngology department for unilateral preauricular swelling, initially treated as parotitis and finally diagnosed as intramuscular masseter haemangioma following imaging and biopsy. However, the patient had to complete several courses of antibiotics and fine needle aspiration, which was inconclusive, for almost a year prior to attaining diagnosis. Conclusion: We would like to highlight early imaging and image-guided biopsy especially in children to avoid delay in diagnosis and prompt management.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47064380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An assessment of short- and long-term efficacy of local corticosteroid injection in patients with lateral epicondylitis","authors":"Piotr Geisler, B. Kisiel, A. Bachta, Sylwia Elert-Kopeć, Weronika Pasińska, W. Tłustochowicz","doi":"10.15557/pimr.2022.0009","DOIUrl":"https://doi.org/10.15557/pimr.2022.0009","url":null,"abstract":"Aim of the study: An assessment of short- and long-term efficacy of local corticosteroid injection in patients with lateral epicondylitis (tennis elbow) based on The Disabilities of the Aim, Shoulder and Hand (DASH) questionnaire and Visual Analogue Scale (VAS), as well as an assessment of long-term treatment efficacy depending on baseline ultrasound disease activity. Materials and methods: A total of 32 patients presenting with tennis elbow and increased blood flow on ultrasound who were treated with local corticosteroid injection were included in the study. Baseline increase in blood flow, pain severity, upper limb function and the subjective response to treatment at 2 weeks (short-term outcomes) and 6 months (long-term outcomes) were assessed. Results: Short-term improvement was achieved in all patients. Long-term improvement was observed in 24 (75%) patients with lower baseline DASH and VAS. Long-term improvement was achieved in 15 (94%) patients in the group with low to moderate baseline disease activity on power Doppler ultrasound (16 patients) and in only 9 (54%) patients in the group with high baseline Doppler disease activity (16 patients). Conclusions: Local corticosteroid injection in patients with tennis elbow who present with increased baseline vascularity on ultrasound seems show short-term efficacy. Negative long-term prognostic factors seem to include significantly increased baseline vascularisation and high baseline DASH and VAS scores. Therefore, it seems reasonable to evaluate these factors before treatment onset, and if abnormalities are found, intensification of treatment or switch to another therapeutic option should be considered.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48210447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric autoimmune neuropsychiatric syndrome in recurrent acute bacterial pharyngitis – a case report","authors":"Renata Pepaś, Łukasz Przysło, R. Bieda, W. Konopka","doi":"10.15557/pimr.2022.0011","DOIUrl":"https://doi.org/10.15557/pimr.2022.0011","url":null,"abstract":"Pharyngitis and tonsillitis, regardless of their aetiology, are one of the most frequent reasons for visiting a family doctor or a paediatrician. Nearly 85% of pharyngitis cases are viral. It is estimated that bacterial throat infection occurs in 15% of schoolage children and in 4–10% of adult patients. Streptococcus pyogenes is the most common cause of bacterial pharyngitis. PANDAS stands for paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. The term is used to describe a subgroup of children and adolescents who develop acute obsessive-compulsive disorder or tics as a result of group A streptococcal infection, such as tonsillitis. The aim of the paper is to describe a case of a 4-year-old boy who presented to the Laryngology Clinic due to recurrent tonsillitis, time-correlated with obsessive-compulsive disorder.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43177740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possibilities of using determination of allelic polymorphism of interleukin-6 G174C and tumour necrosis factor-α G308A genes for the prediction of cardiovascular disorders in children with juvenile idiopathic arthritis","authors":"A. Artsymovych, O. Oshlianska, O. Okhotnikova, Z. Rossokha, O. Popova, N. Medvedeva, Victoriia Vershigora, I. Chaikovsky, O. Kryvova","doi":"10.15557/pimr.2022.0008","DOIUrl":"https://doi.org/10.15557/pimr.2022.0008","url":null,"abstract":"Objectives: Juvenile idiopathic arthritis is a chronic disease that affects the synovial membrane of the joints, but can also lead to secondary lesions of the cardiovascular system. The most important mechanism of myocardial damage is associated with the effect of proinflammatory cytokines. The aim of the study was to propose a method of early detection of cardiovascular system changes and lesions in patients with juvenile idiopathic arthritis based on the determination of allelic polymorphism combined with electrocardiography data. Materials and methods: 102 patients with juvenile idiopathic arthritis underwent a general clinical examination. The overall activity of juvenile idiopathic arthritis was assessed using the Juvenile Arthritis Disease Activity Score. In addition, the patients underwent an electrocardiographic evaluation using the software and hardware complex “Cardioplus P,” which is a portable electrocardiograph providing “signal-averaged” electrocardiography performing the recognition and measurement of amplitude-time parameters, and calculation of secondary electrocardiography parameters. The genotypes of patients were additionally determined by alleles of the TNF-α (G308A) and IL6 (G174C) genes by polymerase chain reaction. Results: The overall number of mutations affects the course of the disease, with two or more mutations being associated with a more aggressive course of the disease, a more pronounced degree of inflammation, and a higher frequency of extra-articular lesions. The complex indicator of the functional state of the myocardium according to the electrocardiography data differed significantly (p = 0.00001) in clusters. Conclusion: Patients with juvenile idiopathic arthritis with two or more mutations in different genes of proinflammatory cytokines have a higher activity of the inflammatory process and a higher frequency of cardiovascular changes according to 4th generation electrocardiography. The determination of polymorphism may be useful in evaluating the risk of development of cardiovascular system abnormalities.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41516057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A quick glance at docosahexaenoic acid fortification in formulated milk for infants, from animal models to clinical studies: a review","authors":"Irwanto, Ilham Ikhtiar","doi":"10.15557/pimr.2022.0004","DOIUrl":"https://doi.org/10.15557/pimr.2022.0004","url":null,"abstract":"Docosahexaenoic acid is a fatty acid found naturally in plants oil, fish oil, fish meat, seafood flaxseed, algae, and egg yolk. It is one of the long-chain unsaturated fatty acids that are important for human biochemistry. As an important component of grey matter, docosahexaenoic acid is subject to intense research in the field of neurodevelopmental study. It is needed mainly in the third trimester of pregnancy for optimal foetal brain growth and mother’s docosahexaenoic acid intake is known to be important in supplying the foetal needs. However, arguments still exist on whether docosahexaenoic acid status is essential or non-essential for infants, especially in the preterm infant population. In the past, strong arguments coming from translational studies showed the benefits of supplementation of docosahexaenoic acid in developing foetuses and infants. Hence, docosahexaenoic acid supplementation has long existed as commercially available docosahexaenoic acid-fortified formula milk. However, the benefit of this supplementation remains controversial after follow-up in human-based studies and clinical trials. The discovery of the fatty acid desaturase gene and its significance in regulating human docosahexaenoic acid and polyunsaturated fatty acids levels also seemed to give new evidence basis for docosahexaenoic acid supplementation in infants. This literature review attempts to explain the current understanding of clinical benefit of docosahexaenoic acid-fortified milk for infants, starting from the translational study level to clinical trials.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44072012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of diet in the pathogenesis and treatment of acne vulgaris","authors":"Bartosz Pałdyna, Damian Dyńka, Magdalena Pałdyna","doi":"10.15557/pimr.2022.0002","DOIUrl":"https://doi.org/10.15557/pimr.2022.0002","url":null,"abstract":"Acne vulgaris is a common, chronic, multifactorial inflammatory skin disease. Although the disorder occurs primarily in young people, with a peak incidence in adolescence, it quite often persists into adulthood. The views on the impact of diet on the development and course of acne have changed dramatically over the years. Since the 1930s, patients have been advised to avoid chocolate and other sugar-containing products, fatty foods and sugar, and even reduce the overall intake of carbohydrates. Research in the years that followed undermined the influence of nutrition on acne, hence the use of specialised diets was not recommended. Since the beginning of the 21st century, there has been a certain renaissance in research on this relationship and a growing body of evidence has been accumulated to support the important role of different food products in the etiopathogenesis of acne. Most investigations focus on products with a high glycaemic index, as well as chocolate and dairy products. While the current research cannot be used as a basis for developing clear recommendations for patients, there is evidence that low-glycaemic index meals with reduced dairy, sugar, saturated fat and salt consumption, as well as increased omega-3 intake and probiotic supplementation may have a positive effect on the course of acne and its treatment. It should be remembered that although dietary interventions may support the therapeutic process, they will not replace appropriate pharmacological treatment adjusted to the severity of acne.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42052462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sepsis and Streptococcus agalactiae meningitis in a 3-month-old boy","authors":"A. Będzichowska, Karolina Piotrowska-Lis, Paulina Rychcik, B. Kalicki, A. Rustecka, A. Tomaszewska","doi":"10.15557/pimr.2022.0010","DOIUrl":"https://doi.org/10.15557/pimr.2022.0010","url":null,"abstract":"Streptococcus agalactiae bacteria are a common cause of neonatal sepsis and meningitis. Universal screening of pregnant women for carriage and intrapartum antibiotic prophylaxis has significantly reduced the disease prevalence in children up to 7 days of age. However, it is to be remembered that group B streptococcal infection can also affect older children, even if their mothers have tested negative for Streptococcus agalactiae during pregnancy or underwent complete perinatal antibiotic prophylaxis. This paper presents a clinical case of a 3-month-old boy treated for sepsis and Streptococcus agalactiae meningitis. The baby was born on time, with normal body weight. The infection occurred despite full maternal ampicillin perinatal therapy in the mother.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49383453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-office drainage of a frontoethmoidal mucocele with non-axial proptosis: an alternative to operating-room drainage","authors":"R. Thomas, S. Hitam, N. E. Hassan, F. Zahedi","doi":"10.15557/pimr.2021.0060","DOIUrl":"https://doi.org/10.15557/pimr.2021.0060","url":null,"abstract":"Mucocele of the paranasal sinus is a cystic lesion with accumulation of mucus within the sinus walls, which is capable of expansion. The frontal sinus is most commonly involved, whereas ethmoidal, sphenoid, and maxillary mucoceles are rare. The floor of the frontal sinus is shared with the superior orbital wall, which explains orbital displacement in enlarging frontal mucoceles. This article presents a case of a spontaneous right frontoethmoidal mucocele with non-axial proptosis in a 26-year-old male patient who was referred by an ophthalmologist to our ENT (ear, nose, throat) clinic for a biopsy to rule out a sinonasal malignancy. An intranasal endoscopic approach was done to obtain a tissue biopsy in a clinic setting, which turned out to be a both diagnostic and therapeutic procedure with complete resolution of symptoms.","PeriodicalId":42380,"journal":{"name":"Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48162610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}