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Alkoholizm i Narkomania-Alchoholism and Drug Addition最新文献

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MicroRNAs as biomarkers in alcohol use disorder: from diagnostics to therapy. Review of  literature microrna作为酒精使用障碍的生物标志物:从诊断到治疗文献综述
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.104815
A. Mach, G. Gromadzka
{"title":"MicroRNAs as biomarkers in alcohol use disorder: from diagnostics to therapy. Review of  literature","authors":"A. Mach, G. Gromadzka","doi":"10.5114/AIN.2020.104815","DOIUrl":"https://doi.org/10.5114/AIN.2020.104815","url":null,"abstract":"The aim of this paper is to present the current state of knowledge about microRNAs in alcohol use disorder (AUD). Particular emphasis was placed on estimating the possibility of using microRNA molecules as biomarkers of diagnostic, prognostic and predictive significance as well as potential therapeutic targets in alcohol-related disorders. For this purpose the PubMed, Science Direct and Wiley Online Library medical databases were reviewed using the following phrases: “ncRNA”, “microRNA”, “circulating microRNA”, “miRNA”, “alcohol use disorder”, “alcohol addiction”, “alcohol abuse”, “alcoholism”, “bioStreszczenie","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effect of ethanol on the mechanisms of liver antioxidant defence – a review of rodent model studies 乙醇对肝脏抗氧化防御机制的影响——啮齿动物模型研究综述
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.95981
A. Kołota
{"title":"The effect of ethanol on the mechanisms of liver antioxidant defence – a review of rodent model studies","authors":"A. Kołota","doi":"10.5114/AIN.2020.95981","DOIUrl":"https://doi.org/10.5114/AIN.2020.95981","url":null,"abstract":"The consumption of ethanol disturbs oxida-tive-reductive balance in the liver leading to oxidative stress, which plays an glutathione, as well as increased activity of glutathione reductase, while in the case of catalase and glutathione peroxidise, depending on the study, there is either an increase or decrease of these enzymes activity in the liver. This may be due to the age and gender of animals, different experimental conditions, exposure time, ethanol solution dosage and concentration as well as the methods of administration of the ethanol solution. It should be noted that the experiments were conducted mainly on male rats or mice, which, compared to females, are less susceptible to alcohol-induced damage, and more to oxidative stress, which may have also affected the observed results.","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Scale of Excessive Use of Social Networking Sites – the psychometriccharacteristics and validity of a proposed tool 过度使用社交网站的规模——一个拟议工具的心理测量特征和有效性
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/ain.2020.101800
Martyna Kotyśko, M. Michalak
{"title":"The Scale of Excessive Use of Social Networking Sites – the psychometric\u0000characteristics and validity of a proposed tool","authors":"Martyna Kotyśko, M. Michalak","doi":"10.5114/ain.2020.101800","DOIUrl":"https://doi.org/10.5114/ain.2020.101800","url":null,"abstract":"Introduction: The paper describes the process of developing a tool to measure social networking site addiction among adolescents, that is the Scale of Excessive Use of Social Networking Sites (SEUS). Material and methods: Three studies (Study 1, N = Study 2, N = 351; Study 3, N = 1054) were performed to establish psychometric properties, construct and criterion validity of SEUS Słowa among Polish high school students. Two different versions of SEUS were developed (48- and 30-item). Their results were correlated with the Bergen Facebook Addiction Scale (BFAS) and standardised questionnaires for measuring psychological variables. Results: SEUS construct validity was checked with Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) procedures. The long 48-item version was reduced to 14 items on which SEUS-14 is based. The final one-factor solution explained 57.7% of variance. The reliability measured with Cronbach’s α is very good. SEUS-14 correlates with BFAS and psychological measures of personality traits, narcissism, self-esteem and Behavioural Activation System, which confirms the scale criterion validity. Discussion: The presented study findings are consistent with the results of other research on Facebook or internet addiction. Regarding the construct validity, one-factor solution turned out to be the best while correlation analysis confirmed SEUS criterion validity. Conclusions: SEUS-14 has demonstrated good psychometric properties in a national sample of Polish adolescents. The measure, treated as a screening tool, can be used for scientific purpose though further studies on the broader use of the scale are necessary.","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A systematic review and meta-analysis of three clinical trials with Acceptance and Commitment Therapy for problematic pornography use 接受与承诺疗法治疗问题性色情使用的三个临床试验的系统回顾与荟萃分析
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/ain.2020.101802
M. Ghazanfarpour, Masoudeh Babakhanian, A. Keshtkar, M. Kiani
{"title":"A systematic review and meta-analysis of three clinical trials with Acceptance and Commitment Therapy for problematic pornography use","authors":"M. Ghazanfarpour, Masoudeh Babakhanian, A. Keshtkar, M. Kiani","doi":"10.5114/ain.2020.101802","DOIUrl":"https://doi.org/10.5114/ain.2020.101802","url":null,"abstract":"","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"33 1","pages":"275-282"},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/ain.2020.101802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mobile applications for alcohol dependent persons as tools supporting the recovery process 为酒精依赖者提供的移动应用程序，作为支持康复进程的工具
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.95978
J. Klingemann, M. Wróblewski, Łukasz Wieczorek
{"title":"Mobile applications for alcohol dependent persons as tools supporting the recovery process","authors":"J. Klingemann, M. Wróblewski, Łukasz Wieczorek","doi":"10.5114/AIN.2020.95978","DOIUrl":"https://doi.org/10.5114/AIN.2020.95978","url":null,"abstract":"Introduction: The objective of the study was to assess the potential of publicly available mobile applications created as tools supporting the recovery of alcohol-dependent persons. Material and methods: Fifteen mobile applications were analysed in domains liketype of included functionalities and their educational content, engagement and aesthetics, scope and privacy concern. Modified versions of Self-Help Model Scale (SHMS) and Mobile Application Rating Scale (MARS) were used for evaluation. Results: All applications got a low score on SHMS (1-18 points); the average score was only Streszczenie Wprowadzenie: Celem badania była ocena potencjału dostępnych w domenie publicznej aplikacji mobilnych do uzależnionych alkoholu jako narzędzi wspierających proces leczenia alkoholu. Słowa 4 points (min. = 1, max. = 7.7). Most applications received points on educational and motivational level, only two applications contained functionalities related to development of coping strategies in high risk situations. Results of scoring on MARS subscales (min. 1, max. 5 points) were higher. The functionality of applications was as-sessed as rather high (average score 4 points), the lowest score was related to the quality of information (average score 2 points). The average score of app features directly related to coping with alcohol use disorder (AUD) was 3 points (min. = 1.2, max. = 4.1). Applications which were scored high on the MARS were also scored relatively highest on SHMS. Researchers were unable to identify any scientific studies conducted in order to assess the efficacy of those applications as tools supporting the persons with AUD in their recovery process. Conclusions: Mobile applications for persons ex-periencing alcohol-related problems are focused mainly on self-monitoring. It seems important that other domains like the motivational, educational, and related to crisis intervention and forms of social support are being developed as well. The concern about lack of privacy has been identified as one of major challenges.","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Plasma ghrelin in alcohol-dependent patients treated in addiction inpatientcentres – preliminary research 在成瘾住院中心治疗的酒精依赖患者血浆胃饥饿素的初步研究
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/ain.2020.101801
D. Czarnecki, M. Ziółkowski, J. Budzyński, B. Góralczyk, E. Żekanowska
{"title":"Plasma ghrelin in alcohol-dependent patients treated in addiction inpatient\u0000centres – preliminary research","authors":"D. Czarnecki, M. Ziółkowski, J. Budzyński, B. Góralczyk, E. Żekanowska","doi":"10.5114/ain.2020.101801","DOIUrl":"https://doi.org/10.5114/ain.2020.101801","url":null,"abstract":"Introduction: Ghrelin is an orexigenic peptide produced mainly in gastric mucosa that may increase food hunger and likely psychoactive substance, including alcohol, craving. The aim of the study was to estimate blood ghrelin con-Streszczenie centration in alcohol-dependent patients (ADP) centres. Material and methods: Blood ghrelin concentration was examined twice in 67 alcoholics at the beginning of the study and after four weeks of alcohol abstinence, and in 61 social drinkers (control group) at the beginning of the study. Clinical, biochemical and anthropometric parameters of nutritional status were determined in all the study participants. Results: At the beginning of the study, ghrelin blood concentration was significantly lower in the studied persons than those from the control group. The ghrelin concentration in alcohol-de-pendent patients during four-week therapy increased. The independently to changes of ghrelin concentration alcohol craving did not increase and hunger remained stable. These changes of ghrelin were accompanied by an increase in body mass index (BMI) and mid muscle circumference as state of protein nutrition. Discussion: Further studies are needed to explain the clinical importance of the reverse relationships between blood ghrelin concentration and nutritional status in alcohol-dependent patients. Conclusions: The concentration of endogenus ghrelin in blood probably does not seem to be associated with alcohol craving but only with the intensity of drinking and alcohol-dependent patients’ nutritional status.","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
FTO gene variants and consumption of  alcoholic beverages FTO基因变异与酒精饮料的消费
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.104816
A. Flaga, A. Mach, G. Gromadzka
{"title":"FTO gene variants and consumption of  alcoholic beverages","authors":"A. Flaga, A. Mach, G. Gromadzka","doi":"10.5114/AIN.2020.104816","DOIUrl":"https://doi.org/10.5114/AIN.2020.104816","url":null,"abstract":"Authors’ contribution/Wkład pracy autorów: Study design/Koncepcja badania: A.K. Flaga, A. Mach, G. Gromadzka; Data collection/ Zebranie danych: A.K. Flaga, A. Mach, G. Gromadzka; Data interpretation/Interpretacja danych: A.K. Flaga, A. Mach, G. Gromadzka; Acceptance of final manuscript version/Akceptacja ostatecznej wersji pracy: A. Mach, G. Gromadzka; Literature search/Przygotowanie literatury: A.K. Flaga, G. Gromadzka","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risks of alcohol abuse, alcoholism and stress-related drinking during the COVID-19 pandemic COVID-19大流行期间酒精滥用、酒精中毒和压力相关饮酒的风险
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.95762
J. D. Silva, G. Testino
{"title":"Risks of alcohol abuse, alcoholism and stress-related drinking during the COVID-19 pandemic","authors":"J. D. Silva, G. Testino","doi":"10.5114/AIN.2020.95762","DOIUrl":"https://doi.org/10.5114/AIN.2020.95762","url":null,"abstract":"Alcohol consumption in the COVID-19 era is a health emergency Loneliness and social distancing cause alcohol abuse Alcohol consumption through a continuum during the isolation period has created new cases of alcohol use disorders To all this, we must add the increased risk of infection and deteriorating symptoms In fact, it is known that ethanol reduces the activity of adaptive and acquired immunity and promotes the expression of ACE2 receptors Healthcare institutions are required to inform citizens properly about alcohol-related problems in this emergency period","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Analysis of employee’s sick leave from Poland in 2012-2017 due to mental and behavioural disorders 2012-2017年波兰员工因精神和行为障碍请病假的分析
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/AIN.2020.95980
S. Leonik, Michał Smoczok
{"title":"Analysis of employee’s sick leave from Poland in 2012-2017 due to mental and behavioural disorders","authors":"S. Leonik, Michał Smoczok","doi":"10.5114/AIN.2020.95980","DOIUrl":"https://doi.org/10.5114/AIN.2020.95980","url":null,"abstract":"In recent years, there has been a disturbing increase in the number of cases of sick leave due to mental and behavioural disorders taken by employees in Europe. This has also been noted in Poland and our study attempts to analyse the trend and investigate it in the light of related current knowledge. In qualitative terms, sick leave can serve as a measurable indicator of the social state of health and be accepted complementary to quantitative analysis. In the context of mental and behavioural disorders, it clearly emphasises the increase in patient self-awareness and shows the deficiencies in this sector of health care. Between 2012 and 2017, an increase in the number of days of absence due to mental and behavioural disorders in Poland was detected. Between 2012 and 2016, a significant Streszczenie","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71046738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forecasting trends in hospitalisations due to drug poisoning in Semnan, Iran up to 2021: time series modelling 预测到2021年伊朗Semnan因药物中毒住院的趋势:时间序列模型
IF 0.3
Alkoholizm i Narkomania-Alchoholism and Drug Addition Pub Date : 2020-01-01 DOI: 10.5114/ain.2020.99871
M. Moosazadeh, M. Afshari, Somayeh Rezaie, Zahra Sahraie, M. Ghazanfarpour, Masoudeh Babakhanian
{"title":"Forecasting trends in hospitalisations due to drug poisoning in Semnan, Iran up to 2021: time series modelling","authors":"M. Moosazadeh, M. Afshari, Somayeh Rezaie, Zahra Sahraie, M. Ghazanfarpour, Masoudeh Babakhanian","doi":"10.5114/ain.2020.99871","DOIUrl":"https://doi.org/10.5114/ain.2020.99871","url":null,"abstract":"Introduction: Investigating and forecasting the changes in the frequency of referrals to the treatment centres of the patients with drug poisoning can aid the assessment of the burden of health problems and planning of appropriate intervention programmes. The aim of this study is to predict the trend of drug poisoning case referrals to the Iranian hospitals up to 2021. Material and methods: The Box & Jenkins model was applied in a longitudinal study to forecast the frequency of drug and alcohol poisoning surveys, which showed that drug abuse prevalence in Iran is higher than the global mean, were also confirmed by our research. The limitation of our study is the lack of access to the full information on psychoactive substance consumption as well as classified information like police and national registry system da-tabases. Conclusions: Our study revealed a rising trend for drug poisoning patients referred to the studied hospitals. The forecasting also suggested that the trend will continue up to 2021 without suitable intervention.","PeriodicalId":42147,"journal":{"name":"Alkoholizm i Narkomania-Alchoholism and Drug Addition","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71047409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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