{"title":"Comparison of red blood corpuscle indices versus hemoglobin high-performance liquid chromatography as a screen for hemoglobinopathies in pregnant women","authors":"JasvinderKaur Bhatia, Arnab Sengupta, Jasdeep Singh, Manisha Agarwal, Brajesh Singh, RavjotSingh Bhatia","doi":"10.4103/jmms.jmms_21_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_21_23","url":null,"abstract":"Introduction: Beta-thalassemia plagues India and thalassemia screening of pregnant women is crucial. Hemoglobin (Hb) high-performance liquid chromatography (HPLC) (Hb-HPLC) is the gold standard, however in distant places it is rarely an option. While data on the use of red blood cell (RBC) indices to screen pregnant women for thalassemia trait is still developing, a sensitive and specific RBC index is needed to test for beta thalassemia. In service situations, these affordable indices may be useful without HPLC. Objective: We aimed to determine the role of red blood corpuscle indices as a screening tool to differentiate between iron deficiency anemia (IDA) and hemoglobinopathies in pregnant women and to find out the most sensitive and the most specific index. Methods: With ethical approval, 500 patients were evaluated from February 2020 to August 2021. Complete blood Counts and peripheral blood smears were performed. Participants with microcytic hypochromic anemia were included. On these patients, the RBC indices (i) Shine and Lal, (ii) Mentzer’s index, (iii) red cell distribution width index, and (iv) Srivastava were calculated. Ferritin, iron, and total iron-binding capacity levels were also tested. Hb-HPLC was utilized as the gold standard. The Mann– Whitney U-test was used to compare continuous variables between groups. Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were calculated for various metrics. A P < 0.05 was statistically significant. Results: Hb-HPLC showed 29 (5.8%) heterozygous beta thalassemia and 471 (94.2%) IDA. Based on the updated cutoff value (4.727), Srivastava Index was the best screening tool. Conclusion: RBC indices can distinguish IDA from beta thalassemia in pregnant women and are valuable screening tools in service settings.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"138 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136202327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prospective audit of requisitions for transfusion at a rural tertiary care hospital in central India as a step to improve transfusion practices","authors":"VitaladevuniBalasubramanyam Shivkumar, VihankaDevchand Vaidya, AbhayVilas Deshmukh, ManishArun Meshram","doi":"10.4103/jmms.jmms_16_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_16_23","url":null,"abstract":"Introduction: A blood requisition form is the sign of final clinical decision for the transfusion. It provides all the clinical details of the patient. The missing and incorrect information in blood request form can be the cause of error and transfusion reactions. This study was aimed to evaluate blood transfusion request form for its correctness and completeness. Based on its findings and results, the clinicians will be asked to take corrective measures. Methods: The blood requisition forms were evaluated in the blood centre at central India during the period of October 2019 to June 2021 and were analysed. Results: 15022 blood requisition forms were received for 19904 units of blood and blood products during the study period. Majority of the requisitions were for single unit. 10.75% forms were without demographic details, 14.58% were without priority, 18.91% were without mentioning of blood group, 32.69% were without mentioning of indication, 24.23% forms were without history of previous transfusion and 23.47% forms were without proper clinical history. Conclusion: The requests for whole blood was much more than packed red cells. More than 60% forms were not properly filled and without proper clinical information. The indication for transfusion of blood and blood components were not mentioned in 33% of the forms. The forms in which indications were mentioned, more than 30% had inappropriate indications. Thus, it is important to sensitize the clinicians about the importance of correctness and completeness of blood transfusion request forms to ultimately improve the clinical practices.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136202933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Rai, K. Yasaswi, Rishi Raj, R. Hiremath, Smakshi Singh
{"title":"Can intrauterine infusion of granulocyte colony-stimulating factor or platelet-rich plasma increase implantation rate in women undergoing in vitro fertilization with normal endometrium: boon or bane?","authors":"S. Rai, K. Yasaswi, Rishi Raj, R. Hiremath, Smakshi Singh","doi":"10.4103/jmms.jmms_89_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_89_22","url":null,"abstract":"Objective: The objective of this study was to investigate if intrauterine infusion of granulocyte colony-stimulating factor (G-CSF) or platelet-rich plasma (PRP) can improve endometrial parameters and the pregnancy rate in patients undergoing fresh embryo transfer with normal endometrial thickness. Materials and Methods: We conducted a retrospective observational study, at one of the assisted reproductive technique centers in central India. Data were collected from the institutional record system which was established as per the standard protocols. Data on a total of 225 patients who had an endometrial thickness >7 mm without any adjunct and underwent fresh embryo transfer in their first in vitro fertilization cycle during the past 2 years were collected and were categorized into three groups: Group A who had received intrauterine infusion of G-CSF (n = 75), Group B who received intrauterine infusion of PRP (n = 75), and Group C who (control group) received no intervention (n = 75). Results: The implantation rate was significantly higher in Group A (37.24%) than in Groups B and C (21.91% and 21.37%, respectively). No significant difference was found in the clinical pregnancy rate among Groups A, B, and C (50.68%, 40.54%, and 37.84%, respectively). Endometrial thickness increased significantly in Group A by approximately 2.3 mm. No significant change in other endometrial parameters in the three groups. The number of biochemical pregnancies was higher in the G-CSF group compared to the other two groups. Conclusion: Intrauterine infusion of G-CSF in women receiving fresh embryo transfer with normal endometrial thickness can increase endometrial thickness and the implantation rate without affecting other endometrial parameters and the cumulative pregnancy rate.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"81 - 87"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41587628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josemine Davis, D. Dwivedi, Sadhan Sawhney, A. Rai, A. Dua, Satyen Singh
{"title":"A comparison of two techniques of internal jugular vein cannulation: Landmark-guided technique versus ultrasound-guided technique","authors":"Josemine Davis, D. Dwivedi, Sadhan Sawhney, A. Rai, A. Dua, Satyen Singh","doi":"10.4103/jmms.jmms_13_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_13_22","url":null,"abstract":"Background: This study was designed to compare the overall success rates and complications of two techniques of internal jugular vein (IJV) catheterization, namely the landmark (LM)-based technique and ultrasound (US)-guided technique in a heterogeneous Indian population at an Armed Forces Tertiary Care Hospital. Methods: Ninety consenting patients were assigned to two groups: LM and US groups. Patients with known coagulation abnormalities, body mass index > 30, infection at the insertion site, known vascular abnormalities, burn contractures, and other dermatologic conditions that precluded an LM technique were excluded. Central venous catheterizations during the code blue scenarios were excluded due to the emergent nature of the procedure. Three operators from the author group with requisite experience in LM and US techniques performed the 90 catheterizations. In LM group, a finder needle with a 2 ml syringe was used to aspirate venous blood from the IJV. A 16G needle was guided in the same direction as the finder needle till venous blood was aspirated, followed by guidewire insertion and cannulation. In the US group, a 6–12 MHz linear US probe was used to identify the IJV in real time and a 16G needle was used to access the IJV under US guidance in the cross-sectional view. Results: The overall success rate was 84.4% in LM group and 100% in US group (P = 0.0059). The first attempt success rate was similar in both groups (71.1% and 86.6%, P = 0.07). The overall complication rates in LM group were 20%, whereas complications in the US group were 2.2% (P = 0.0073). Notably, vascular complications occurred less frequently in US group with fewer arterial punctures and hematomas. Hemothorax and pneumothorax did not occur in any group. The mean cannulation time decreased by 69 s, i.e., from 276 s in the LM group to 207 s in the US group (P < 0.001). Conclusion: US-guided central venous catheter insertion to IJV improves the overall success rate and reduces cannulation time as compared to conventional LM-based technique.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"31 - 36"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47237552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priya Ranjan, V. Jha, V. Nair, Sibi Eranki, O. Singh
{"title":"Clinical Spectrum of Gossypiboma: Case Series and Review of Literature","authors":"Priya Ranjan, V. Jha, V. Nair, Sibi Eranki, O. Singh","doi":"10.4103/jmms.jmms_75_21","DOIUrl":"https://doi.org/10.4103/jmms.jmms_75_21","url":null,"abstract":"Gossypiboma is a term used to describe retained surgical sponge after surgery. This is an avoidable clinical condition causing significant morbidity and mortality. The clinical presentation is variable and often a diagnostic enigma. The consequences of gossypiboma are undesirable, disappointing, and have medicolegal implications for the surgical team. We report three cases of gossypiboma with varying clinical spectrums. The first case had gastric outlet obstruction due to retained surgical sponge after open cholecystectomy. It had eroded both into the first part of the duodenum and transverse colon. Endoscopic and radiological evaluation helped to establish the diagnosis of duodenocolic fistula with gastric outlet obstruction. The second patient was treated for penetrating abdominal wound and presented with persistent fever with discharging sinus at the wound site. The third patient had undergone exploratory laparotomy for recurrent hydatid cyst of the liver and, in addition to recurrent hydatid cyst, a surgical sponge was also found. All these patients had retained surgical sponges but different clinical presentations. These patients underwent exploratory laparotomy and surgical removal of the retained surgical item (RSI) followed by a successful recovery. Gossypiboma should be considered as a differential diagnosis in all unexplained postoperative sepsis, intestinal obstruction, and intra-abdominal mass. Standard surgical safety measures in the operative room help to prevent the incidence of RSIs.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"93 - 96"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44372842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study to carry out always better control and vital, essential, and desirable analysis in the dispensary of a tertiary care teaching hospital","authors":"Neelesh Patel, Balpreet Kaur, Neeraj Garg, Vasudev Gad","doi":"10.4103/jmms.jmms_183_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_183_22","url":null,"abstract":"Introduction: Due to the advancement of medical technology, it is difficult to monitor the vast inventory in hospitals. Thirty-three percentage of the hospital operating budget are spent on buying materials and supplies. Out of all the inventory control measures, Always better control (ABC) and Vital, essential, and desirable (VED) are the most used inventory control techniques. The present study was conducted at a tertiary care specialty hospital to study drug management through the application of inventory control techniques. Aim and Objectives: The present study aimed at studying the drug management system by application of ABC and VED analysis and to give recommendations for an efficient inventory management system. Materials and Methods: It was an observational study conducted at the dispensary of a tertiary care teaching hospital. The data of annual consumption and expenditure incurred on each item of the dispensary for the fiscal year 2021–2022 were collected. The annual expenditure of individual items was arranged in descending order. The cumulative cost percentage and the cumulative percentage of number of items were calculated, and the list was then categorized into three subdivisions: A, B, and C categories. For classifying drugs into VED, inputs from the concerned clinicians were sought. Data were analyzed using statistical tools of MS Excel. ABC-VED matrix was formed to couple the items into various categories and groups so that managers can efficiently monitor them. Results: Of the 291 items used, 15% of the items were A items which need strict monitoring by the top-level management as they are the costliest. VED analysis revealed 37% of the items as vital which should be present at all times in the hospital and are inescapable requirements. ABC-VED matrix analysis showed 10% of the items as A items from ABC and vital items from VED (AV) items which are costly and should be present at all times at the hospital, thereby demanding strict managerial control. Conclusion: Using inventory control techniques, substantial improvement could be brought about in patient care by ensuring the uninterrupted availability of vital and essential medicines all the time. It can also be used to identify drugs that require stringent control for the optimal use of financial resources and the elimination of out-of-stock conditions at the dispensary.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136202538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quiz in PG teaching: Are we adapted to new methods in learning?","authors":"Anuj Singhal, Rajat Shukla, SubashChandra Shaw, Mahesh Manthene, Shrimukta Sahoo, Aditya Singhal","doi":"10.4103/jmms.jmms_8_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_8_23","url":null,"abstract":"Introduction: Traditional methods of teaching residents in medicine are lectures, symposiums, case presentations and CMEs. Students have different levels of attitude about learning and responses to specific environments. A sound understanding of the changing trends in medical education is crucial to the accurate implementation of adequate training protocols which helps in good perception of subject by students. Novel ideas and concepts must pave way for modern methodologies of teaching. Methodology: We administered the peer validated questionnaire to 30 Junior residents(JRs) who participated in the quiz on Diabetes. JRs were informed about quiz 10 days prior and adequate material was shared with them. Results: More than half of the students (56.7%) responded that the quiz was better enjoyed than discussing the similar topic in class room teaching, maximum students (86.7%) responded that the quiz should be inculcated in postgraduate curriculum. Conclusion: This kind of novel methods helps the students to have good understanding and perception of the subject rather than routine teaching methods and helps to make an impact.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136203267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcome of single and double intrauterine insemination techniques in infertility cases","authors":"Mustajib Ali, Arunav Sharma, Rajesh Sharma","doi":"10.4103/jmms.jmms_50_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_50_23","url":null,"abstract":"Background: Primary infertility is a serious condition that has a profound impact on the mental and physical health of the couple, and the condition forms a significant proportion of cases seeking treatment at gynecological centers across the world. Intrauterine insemination (IUI) forms the cornerstone in the management of most of such cases. However, there has been an ongoing debate regarding whether single IUI or double IUI: which is better. This randomized control trial aims at comparing the outcomes of both the techniques. Materials and Methods: In this randomized control trial, 150 couples having a valid indication for IUI were randomized into two groups. In the first group, single IUI was done at 36 h after human chorionic gonadotropin (HCG) trigger, and in the second group, double IUI was done at 24 and 48 h post-HCG trigger. The outcome measured was pregnancy which was confirmed by urine pregnancy test done on the 18th day after IUI and later followed up till appearance of gestation sac with fetal pole on ultrasound. The Fisher’s exact test for statistical analysis was used to analyze the data for statistical significance. Results: In the single IUI cohort of 75 women, 11 tested positive for urine beta-HCG on day 18 and all had confirmed pregnancy (gestational sac with fetal pole). The pregnancy positivity rate for this cohort was 14.67% (11/75 × 100%). In the double IUI cohort of 75 women, 13 tested positive for urine beta-HCG on day 18 and all had confirmed pregnancy (gestational sac with fetal pole); the pregnancy positivity rate for this cohort was 17.33% (13/75 × 100%). Although the double IUI group had a higher yield of positive outcomes, the result was not statistically significant (statistic test value is 0.8242). Conclusion: The outcome of single versus double IUI is almost similar. In a resource-poor situation, it will be prudent to stick to single IUI in all cases requiring IUI. However, in a resource-rich situation, one might resort to double IUI in male factor abnormalities such as asthenozoospermia or borderline oligozoospermia.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136202095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}