Global Cardiology Science and Practice最新文献_第3页

Aswan Heart Centre: Fundamental values 阿斯旺心脏中心：基本价值观

Global Cardiology Science and Practice Pub Date : 2023-12-07 DOI: 10.21542/gcsp.2024.1

Ingi Farid

引用次数: 0

Determining whether LV filling time contributes to HF symptoms in different widths of QRS in LBBB patients: a clinical study 确定 LV 充盈时间是否对 LBBB 患者不同 QRS 宽度的房颤症状有影响：一项临床研究

Global Cardiology Science and Practice Pub Date : 2023-12-07 DOI: 10.21542/gcsp.2024.8

Masoumeh Ahmadzadeh, Mehran Rahimi, Mehrnoush Toufan-Tabrizi, Kamran Mohammadi

{"title":"Determining whether LV filling time contributes to HF symptoms in different widths of QRS in LBBB patients: a clinical study","authors":"Masoumeh Ahmadzadeh, Mehran Rahimi, Mehrnoush Toufan-Tabrizi, Kamran Mohammadi","doi":"10.21542/gcsp.2024.8","DOIUrl":"https://doi.org/10.21542/gcsp.2024.8","url":null,"abstract":"Objectives: Accurate assessment of left ventricular (LV) function is essential for managing patients with left bundle branch block (LBBB). This study aimed to evaluate the relationship between LV systolic function, left ventricular diastolic filling time (LVFT), QRS duration, and heart failure symptoms in patients with LBBB.\u0000Methods: This study was conducted between June 2021 and June 2022. Patients with LBBB and sinus rhythm who were referred to the echocardiography department were included in the study. All the patients underwent electrocardiogram-gated echocardiography using the same machine. In this study, the LVFT value was measured in absolute terms and as a ratio to the R-R interval (LVFT/RR).\u0000Results: A total of sixty-five patients were included, forty-two (64.6%) were women, and the mean age was 60.71 ± 8.72. We performed three one-way ANOVA tests that showed that LV filling time/RR ratio, QRS duration, and ejection fraction were significantly different between heart failure classes (p=0.008, p=0.001, and p<0.001, respectively). A weak correlation was observed between LVEF and LVFT/RR (r= 0.349, p=0.004). Additionally, QRS duration was negatively correlated with LVEF (r = -0.395, p=0.004) and LVFT/RR (r = -0.350, p=0.004), although these correlations were weak.\u0000Conclusion: We showed that LVFT/RR ratio differed significantly between HF functional classes and was lower in patients with more severe HF symptoms. Additionally, QRS duration was negatively correlated with LVEF and LVFT/RR, and patients with more severe HF symptoms had longer QRS durations.","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138590223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural aortic wall abnormalities following the Nikaidoh operation, which could be reversible and include a healing process 尼凯多手术后主动脉壁结构异常，这可能是可逆的，包括一个愈合过程

Global Cardiology Science and Practice Pub Date : 2023-12-07 DOI: 10.21542/gcsp.2024.3

Magdi Yacoub, A. Afifi, Hatem Hosny, Ahmed Nahgoub, Mohamed Nagy, Sanida Vaz, P. Sarathchandra, N. Latif

引用次数: 0

Navigating the challenges of bicuspid aortic valve-aortopathy 导航二尖瓣主动脉瓣病变的挑战

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.27

Sai Gautham Kanagala, Aanchal Sawhney, Kinna Parikh, Vasu Gupta, Talha Mahmood, FNU Anamika, Rohit Jain, Nikita Garg

{"title":"Navigating the challenges of bicuspid aortic valve-aortopathy","authors":"Sai Gautham Kanagala, Aanchal Sawhney, Kinna Parikh, Vasu Gupta, Talha Mahmood, FNU Anamika, Rohit Jain, Nikita Garg","doi":"10.21542/gcsp.2023.27","DOIUrl":"https://doi.org/10.21542/gcsp.2023.27","url":null,"abstract":"Bicuspid aortic valve (BAV) is a congenital heart defect that affects 0.5-2% of the general population with familial predominance. The modifications in hemodynamics and structure change at cellular level contribute to the dilation of aorta, resulting in bicuspid aortopathy, which can result in catastrophic aortic events. The American Heart Association recommends screening first-degree relatives of patients with bicuspid aortic valve and aortic root disease. BAV may or may not be associated with a syndrome, with the non-syndromic variety having a higher chance of predisposition to congenital and vascular abnormalities. Many genes have been implicated in the etiology of non-syndromic aortic aneurysm such as ACTA2, MYH11, FLNA, and SMAD3. Common diagnostic modalities include transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), multi system computer tomography (MSCT), and cardiac MRI. Medical management reduces the rate of disease progression and surgical management is indicated based on the diameter of the ascending aorta, which differs in American and European guidelines. Our article aims to explore the current understanding of the pathophysiology, clinical aspects, and surgical management of bicuspid aortic valve disease. Additionally, we have included a discussion on the management of this condition in special populations, such as athletes and pregnant women, who require distinct treatment recommendations.","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136072887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocarditis and COVID-19 related issues 心肌炎和COVID-19相关问题

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.28

Michele Ciabatti, Chiara Zocchi, Iacopo Olivotto, Leonardo Bolognese, Maurizio Pieroni

{"title":"Myocarditis and COVID-19 related issues","authors":"Michele Ciabatti, Chiara Zocchi, Iacopo Olivotto, Leonardo Bolognese, Maurizio Pieroni","doi":"10.21542/gcsp.2023.28","DOIUrl":"https://doi.org/10.21542/gcsp.2023.28","url":null,"abstract":"   The recent COVID-19 (Coronavirus Disease 2019) pandemic by SARS-CoV2 infection has caused millions of deaths and hospitalizations across the globe. In the early pandemic phases, the infection had been initially considered a primary pulmonary disease. However, increasing evidence has demonstrated a wide range of possible cardiac involvement. Most of systemic and cardiac damage is likely sustained by a complex interplay between inflammatory, immune-related and thrombotic mechanisms. Biventricular failure and myocardial damage with elevation of cardiac biomarkers have been reported in COVID-19 patients, although histological demonstration of acute myocarditis has been rarely documented. Indeed while cardiac magnetic resonance findings include different patterns of myocardial involvement in terms of late gadolinium enhancement, histological data from necropsy and endomyocardial biopsy showed peculiar inflammatory patterns, mostly composed by macrophages. On the other hand COVID-19 vaccines based on mRN technology have been also associated with increased risk of myocarditis. COVID-19 and mRNA vaccine-related myocarditis present different clinical and imaging presentations and recent data suggest the presence of distinctive immunological mechanisms involved.  ","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136072889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The catastrophic association of prosthetic mitral valve thrombosis and hemorrhagic stroke 假体二尖瓣血栓形成与出血性中风的灾难性关联

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.31

Humberto Morais, Mauer Gonçalves

引用次数: 0

Reoperative CABG in a patient with prior concomitant lung transplantation and two-vessel CABG 既往合并肺移植和双血管冠脉搭桥患者的再手术

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.25

Emily Larson, Anson Lee, Jennifer Lawton, Hamza Aziz

{"title":"Reoperative CABG in a patient with prior concomitant lung transplantation and two-vessel CABG","authors":"Emily Larson, Anson Lee, Jennifer Lawton, Hamza Aziz","doi":"10.21542/gcsp.2023.25","DOIUrl":"https://doi.org/10.21542/gcsp.2023.25","url":null,"abstract":"Background: Lung transplants (LTx) are being offered to increasingly older patients, and as a result, more concomitant coronary artery disease is being encountered in LTx candidates. While concurrent coronary artery bypass grafting (CABG) and LTx have become more common, the long-term considerations of reoperative CABG in patients following CABG with concomitant LTx are not fully understood. Case presentation: A 75-year-old man with a history of bilateral LTx and concomitant CABG X 2 15 years prior presented to the emergency room with tachycardia and chest discomfort radiating to the left upper extremity. Emergent coronary angiography revealed severe three- vessel coronary artery disease with two occluded saphenous vein grafts, severe distal obtuse marginal (OM) and left circumflex disease, a collateralized chronic total occlusion of the mid LAD, and tortuosity of the proximal right innominate artery. The patient underwent a complex redo sternotomy and CABG X 2 due to dense adhesions in the mediastinum and pleura bilaterally. The postoperative course was complicated by left leg SVG harvest site cellulitis treated with IV antibiotics and hypervolemia treated with diuresis. The patient was discharged postoperatively on day 13. Discussion: To our knowledge, this is the first reported successful reoperative CABG in a patient with a history of concomitant LTx and CABG. This case demonstrates feasibility, though additional caution is required due to the technical complexity and risk of immunosuppression in such complex patients.","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136072888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stress cardiomyopathy as a cardiovascular manifestation of COVID-19 应激性心肌病作为COVID-19的心血管表现

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.29

Khaled Abdullah, Mohamad Bakir, Danielle Greenberg, Eyad Almasri

引用次数: 0

Early detection of reduced left ventricular systolic function by 2D speckle tracking echocardiography in patients with primary mitral regurgitation in a Vietnamese cohort 二维斑点跟踪超声心动图早期检测原发性二尖瓣反流患者左心室收缩功能减退

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.26

Anh Vu Nguyen, Thi Diem Nguyen, Thi To Linh Ong, Viet An Tran, Lam Thai Bao Tran, Minh Chau Tran

{"title":"Early detection of reduced left ventricular systolic function by 2D speckle tracking echocardiography in patients with primary mitral regurgitation in a Vietnamese cohort","authors":"Anh Vu Nguyen, Thi Diem Nguyen, Thi To Linh Ong, Viet An Tran, Lam Thai Bao Tran, Minh Chau Tran","doi":"10.21542/gcsp.2023.26","DOIUrl":"https://doi.org/10.21542/gcsp.2023.26","url":null,"abstract":"Background: Mitral regurgitation (MR) is a common heart valve disease, causing many serious complications in several organ systems, especially the cardiovascular system. The 2D speckle tracking echocardiography (STE) is a new technique for detecting potential cardiac dysfunction when only tissue function abnormalities are present. The study aimed to assess left ventricular (LV) systolic function early by STE in patients with primary MR through global LV deformity along the global longitudinal strain (GLS). Methods: An analytical cross-sectional study was performed on 46 patients with moderate to severe primary MR as recommended by the American Society of Echocardiography (ASE) 2017. Results: The prevalence of patients with GLS reduction with ejection fraction (EF) >60%, New York Heart Association (NYHA) I, and left ventricular internal diameter systolic (LVIDs) <40mm was 38.1%, 35.7%, and 39.5%, respectively. 100% of patients with EF<60% and LVIDs40mm had reduced GLS (<16%). The GLS index strongly correlates with the NYHA classification, degree of MR, EF, and echocardiographic parameters. Conclusion: GLS index gives a significant sign in the early detection of cardiac function abnormalities before symptoms or other echocardiographic parameters in patients with MR.","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136072882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary analysis of REPRISE III trial: The Lotus valve's persistence after withdrawal REPRISE III试验的二次分析:莲花瓣膜停药后的持续性

Global Cardiology Science and Practice Pub Date : 2023-09-10 DOI: 10.21542/gcsp.2023.30

Susy Kotit

{"title":"Secondary analysis of REPRISE III trial: The Lotus valve's persistence after withdrawal","authors":"Susy Kotit","doi":"10.21542/gcsp.2023.30","DOIUrl":"https://doi.org/10.21542/gcsp.2023.30","url":null,"abstract":"Introduction: Aortic stenosis (AS) is the leading heart valve disease in developed countries, often caused by calcific degeneration. In low-and-middle-income countries, it's primarily due to RHD. Prevalence of AS increases with age and up to 22.8% of those affected over the age of 75. While surgical aortic valve replacement is standard treatment for AS, many older individuals are not ideal candidates. Transcatheter aortic valve replacement (TAVR) offers an alternative. The REPRISE III trial showed the Lotus valve outperformed the CoreValve/EvolutR TAVR valves in various metrics over 2 years. Despite its success and over 10,000 implantations, the Lotus valve was pulled from the market, highlighting the need to understand its long-term outcomes. Study and results: In the REPRISE III trial, the long-term outcomes of TAVR using the Lotus valve were compared to the CoreValve/EvolutR over 5 years across 55 global centers. Of the participants, 581 (95.7%) used the Lotus valve and 285 (93.4%) used CoreValve/EvolutR. Event rates for all-cause mortality were similar between the groups, but the Lotus valve group had lower rates of disabling stroke and pacemaker implantation. The Lotus valve showed a higher aortic gradient but lower effective orifice area. Additionally, the Lotus valve had reduced mild PVL, valve...","PeriodicalId":416388,"journal":{"name":"Global Cardiology Science and Practice","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136072883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0