Reoperative CABG in a patient with prior concomitant lung transplantation and two-vessel CABG

Emily Larson, Anson Lee, Jennifer Lawton, Hamza Aziz
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Abstract

Background: Lung transplants (LTx) are being offered to increasingly older patients, and as a result, more concomitant coronary artery disease is being encountered in LTx candidates. While concurrent coronary artery bypass grafting (CABG) and LTx have become more common, the long-term considerations of reoperative CABG in patients following CABG with concomitant LTx are not fully understood. Case presentation: A 75-year-old man with a history of bilateral LTx and concomitant CABG X 2 15 years prior presented to the emergency room with tachycardia and chest discomfort radiating to the left upper extremity. Emergent coronary angiography revealed severe three- vessel coronary artery disease with two occluded saphenous vein grafts, severe distal obtuse marginal (OM) and left circumflex disease, a collateralized chronic total occlusion of the mid LAD, and tortuosity of the proximal right innominate artery. The patient underwent a complex redo sternotomy and CABG X 2 due to dense adhesions in the mediastinum and pleura bilaterally. The postoperative course was complicated by left leg SVG harvest site cellulitis treated with IV antibiotics and hypervolemia treated with diuresis. The patient was discharged postoperatively on day 13. Discussion: To our knowledge, this is the first reported successful reoperative CABG in a patient with a history of concomitant LTx and CABG. This case demonstrates feasibility, though additional caution is required due to the technical complexity and risk of immunosuppression in such complex patients.
既往合并肺移植和双血管冠脉搭桥患者的再手术
背景:肺移植(LTx)正被越来越多的老年患者所接受,因此,在LTx候选者中,更多的合并冠状动脉疾病正在被遇到。虽然同时进行冠状动脉旁路移植术(CABG)和LTx已经变得越来越普遍,但对于CABG合并LTx患者再行CABG手术的长期考虑尚不完全清楚。病例介绍:一名75岁男性,15年前有双侧LTx病史并伴有冠脉搭桥,因左上肢心动过速和胸部不适就诊于急诊室。急诊冠状动脉造影显示严重的三支冠状动脉疾病,伴两条隐静脉移植物闭塞,严重的远端钝缘(OM)和左旋疾病,侧枝性LAD中部慢性全闭塞,右近端无名氏动脉扭曲。由于双侧纵隔和胸膜致密粘连,患者接受了复杂的重做胸骨切开术和CABG x2。术后并发左腿SVG采集部位蜂窝组织炎,静脉注射抗生素治疗,利尿治疗高血容量。患者于术后第13天出院。讨论:据我们所知,这是首例有LTx和CABG合并病史的患者成功再手术CABG的报道。该病例证明了可行性,但由于技术复杂性和这种复杂患者免疫抑制的风险,需要额外的谨慎。
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