Cardiovascular Innovations and Applications最新文献_第9页

Nomogram for Predicting the Severity of Coronary Artery Disease in Young Adults ≤45 Years of Age with Acute Coronary Syndrome 预测≤45岁急性冠脉综合征青壮年冠状动脉病变严重程度的Nomogram

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0016

Wenbin Zhang

{"title":"Nomogram for Predicting the Severity of Coronary Artery Disease in Young Adults ≤45 Years of Age with Acute Coronary Syndrome","authors":"Wenbin Zhang","doi":"10.15212/cvia.2022.0016","DOIUrl":"https://doi.org/10.15212/cvia.2022.0016","url":null,"abstract":"Background: A non-invasive predictive model has not been established to identify the severity of coronary lesions inyoung adults with acute coronary syndrome (ACS).Methods: In this retrospective study, 1088 young adults (≤45 years of age) first diagnosed with ACS who underwentcoronary angiography were enrolled and randomized 7:3 into training or testing datasets. To build the nomogram, wedetermined optimal predictors of coronary lesion severity with the Least Absolute Shrinkage and Selection Operatorand Random Forest algorithm. The predictive accuracy of the nomogram was assessed with calibration plots, and performancewas assessed with the receiver operating characteristic curve, decision curve analysis and the clinical impact curve.Results: Seven predictors were identified and integrated into the nomogram: age, hypertension, diabetes, body massindex, low-density lipoprotein cholesterol, mean platelet volume and C-reactive protein. Receiver operating characteristicanalyses demonstrated the nomogram’s good discriminatory performance in predicting severe coronary arterydisease in young patients with ACS in the training (area under the curve 0.683, 95% confidence interval [0.645–0.721])and testing (area under the curve 0.670, 95% confidence interval [0.611–0.729]) datasets. The nomogram was also well-calibrated in both the training (P = 0.961) and testing (P = 0.302) datasets. Decision curve analysis and the clinicalimpact curve indicated the model’s good clinical utility.Conclusion: A simple and practical nomogram for predicting coronary artery disease severity in young adults ≤45 yearsof age with ACS was established and validated.","PeriodicalId":41559,"journal":{"name":"Cardiovascular Innovations and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67305659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Case of Premature Ventricular Complexes from the Proximal Left Bundle Branch Successfully Ablated from the Right Coronary Cusp 右冠状动脉尖成功消融左束支近端早心室复合体1例

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0006

Jianhua Fan

引用次数: 0

A Rare Case of a Primary Cardiac Tumor Presenting as Fatal Ventricular Tachycardia 原发性心脏肿瘤致死性室性心动过速一例

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0014

Xu-Dong Guo

引用次数: 0

The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease 中性粒细胞/淋巴细胞比值与冠状动脉疾病发展的不同阶段相关

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0018

Jianlin Du

{"title":"The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease","authors":"Jianlin Du","doi":"10.15212/cvia.2022.0018","DOIUrl":"https://doi.org/10.15212/cvia.2022.0018","url":null,"abstract":"Introduction: Inflammation plays a role in coronary artery disease (CAD). The neutrophil/lymphocyte ratio (NLR),monocyte/lymphocyte ratio (MLR) and platelet/lymphocyte ratio (PLR) are blood parameters associated with inflammation.We aimed to perform a systematic comparison and study the predictive values of these inflammatory parameterswith respect to CAD stage.Method: A total of 513 patients who had undergone coronary angiography (CAG) were retrospectively analyzed.Clinical status, lipid profiles, CAG scans and hematological parameters were collected. NLR, MLR and PLR were calculated. All patients were classified into a normal coronary group (n = 133), coronary atherosclerosis (CA) group (n = 149), chronic coronary syndrome (CCS) group (n = 175) or acute myocardial infarction (AMI) group (n = 56). NLR, MLR and PLR were compared among groups.Results: NLR and MLR were higher in the CCS and AMI groups. PLR was higher in the AMI group. The AMI grouphad higher NLR, PLR and MLR than the CCS group. Logistic regression analysis revealed that NLR (OR:1.227, 95%CI: 1.016–1.482. P < 0.05) had a strong significant correlation with CAD. Area under the ROC curve of NLR was 0.580(95% CI = 0.516–0.644) in predicting CCS and 0.727 (95% CI = 0.642–0.811) in predicting AMI.Conclusion: NLR may be associated with the occurrence and progression of CAD, and may serve as a marker of inflammation.","PeriodicalId":41559,"journal":{"name":"Cardiovascular Innovations and Applications","volume":"13 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67305858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Dapagliflozin in Heart Failure with Reduced Ejection Fraction: A Real-World Study 达格列净治疗心力衰竭伴射血分数降低:一项现实世界研究

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0005

Yanzhou Zhang

{"title":"Dapagliflozin in Heart Failure with Reduced Ejection Fraction: A Real-World Study","authors":"Yanzhou Zhang","doi":"10.15212/cvia.2022.0005","DOIUrl":"https://doi.org/10.15212/cvia.2022.0005","url":null,"abstract":"Aims: We aimed to observe the improvements in cardiac function indexes and the occurrence of adverse events in patients with heart failure with reduced ejection fraction (HFrEF) after dapagliflozin administration in a real-world setting.Methods: We retrospectively enrolled 201 patients with HFrEF who were treated at a tertiary hospital in Zhengzhou and started to take dapagliflozin (10 mg/d) from March 2020 to June 2021. Their New York Heart Association (NYHA) functional class, cardiac ultrasound indexes, laboratory indexes, and vital signs between baseline and the last follow-up visit were compared, and their adverse events during the follow-up period were recorded.Results: The follow-up period was 173 (67–210) days. The cardiac function indexes of patients at follow-up, compared with baseline, indicated significant improvement (proportion of NYHA functional class I and II: 40.8% vs. 56.2%; left ventricular ejection fraction: 28.4 ± 5.3% vs. 34.7 ± 5.9%; left ventricular end-diastolic diameter: 70.1 ± 6.4 mm vs. 64.7 ± 5.6 mm; N-terminal pro-B-type natriuretic peptide: 5421.9 ± 2864.4 pg/mL vs. 2842.8 ± 1703.4 pg/mL at baseline vs. at follow-up; all P < 0.05). The rates of hypotension, deterioration of renal function, and genital infection during the follow-up period were 6.5%, 4.0%, and 3.5%, respectively.Conclusions: We believe that dapagliflozin is safe and effective in patients with HFrEF in the real world.","PeriodicalId":41559,"journal":{"name":"Cardiovascular Innovations and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67304968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Novel Robotic Control System Mimics Doctor’s Operation to Assist Percutaneous Coronary Intervention 一种新型机器人控制系统模拟医生手术以辅助经皮冠状动脉介入治疗

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0003

Ping Zhang

{"title":"A Novel Robotic Control System Mimics Doctor’s Operation to Assist Percutaneous Coronary Intervention","authors":"Ping Zhang","doi":"10.15212/cvia.2022.0003","DOIUrl":"https://doi.org/10.15212/cvia.2022.0003","url":null,"abstract":"Objectives: The use of current robotic systems to assist in percutaneous coronary intervention (PCI) fundamentallydiffers from performing conventional PCI. To overcome this problem, we developed a novel master-slave roboticcontrol system to assist in PCI, and evaluated its safety and feasibility in the delivery and manipulation of coronaryguidewires in vitro and in vivo.Methods: The novel robotic assist PCI system is composed of three parts: 1) a master actuator, which imitates thetraditional torque used by surgeons in conventional PCI, 2) a slave actuator, including a guidewire delivery system andforce monitoring equipment, and 3) a local area network based communication system.Results: The experiment was performed in six pigs. Both robotic and manual control completed the operation with no device- or procedure-associated complications. An experienced interventional cardiologist who was a first-time userof the novel robotic PCI system was able to advance the guidewire into a distal branch of a coronary artery within asimilar time to that required with the manual procedure.Conclusion: This early in vivo experiment with the novel robotic assisted PCI control system demonstrated that its feasibility, safety, and procedural effectiveness are comparable to those of manual operation. The novel robotic-assisted PCI control system required significantly less time to learn than other currently available systems.","PeriodicalId":41559,"journal":{"name":"Cardiovascular Innovations and Applications","volume":"93 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67305341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypertensive-Like Reaction: A Definition for Normotensive Individuals with Symptoms Associated with Elevated Blood Pressure 高血压样反应:血压升高相关症状的正常个体的定义

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0004

Yifang Guo

引用次数: 0

Application Potential of Probiotics in Acute Myocardial Infarction 益生菌在急性心肌梗死中的应用潜力

IF 0.5 4区医学

Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI: 10.15212/cvia.2022.0019

Hui Jiang

引用次数: 2

Role of Epicardial Adipose Tissue in Triggering and Maintaining Atrial Fibrillation 心外膜脂肪组织在诱发和维持心房颤动中的作用