Japan Journal of Clinical & Medical Research最新文献_第3页

Eye Injuries in Infants and Babies during Breast Feeding 婴儿和婴儿在母乳喂养期间的眼睛损伤

Japan Journal of Clinical & Medical Research Pub Date : 2022-08-31 DOI: 10.47363/jjcmr/2022(2)138

S. Dixit, Reva Kanash

引用次数: 0

Effects of Ethanolic Leaf Extract of Piper Guineense (Uziza) On The Liver of Paraquat Induced Adult Male Wistar Rats 豚草叶乙醇提取物对百草枯诱导成年雄性Wistar大鼠肝脏的影响

Japan Journal of Clinical & Medical Research Pub Date : 2022-06-30 DOI: 10.47363/jjcmr/2022(2)137

Mbah C A

{"title":"Effects of Ethanolic Leaf Extract of Piper Guineense (Uziza) On The Liver of Paraquat Induced Adult Male Wistar Rats","authors":"Mbah C A","doi":"10.47363/jjcmr/2022(2)137","DOIUrl":"https://doi.org/10.47363/jjcmr/2022(2)137","url":null,"abstract":"Piper guineense (Uziza in Igbo) is a medicinal plant whose leaves are commonly used as spices.This study is to investigate the effects of the ethanolic leaf extracts of P.guineenseon the histology of the liver, liver biomarker enzymes of paraquat-induced Thirty (30) adult male Wistar rats weighing between 160g – 200g which was randomly assigned to six Groups (A-F) of 5 rats each. The control Group A was not induced with paraquat, while Groups B, D, E and F were induced with 20mg/kg of paraquat. Group C received 200mg/kg of the extract only. After the fourteenth day, groups E and F were withdrawn and treated with 80mg/kg and 100mg/kg of the extract, respectively, for another fourteen days; while Group D was withdrawn without treatment.The results showed that animals in all Groups (P<0.05) except B (-21.67 ± 22.55) and D (-12.21 ± 15.67) had decreased in body weight; severely degenerated hepatic tissue with severe aggregates of intra lobular inflammatory cells, sever intra hepatic haemorrhage and necrotic debris around the haemorrhagic area; These effects were ameliorated in Groups E and F which received the variable doses of the ethanolic leaf extracts of P.guineense. The ethanolic leaf extracts of P.guineense have ameliorative effects on the body weight, serum levels of ALT, AST, ALP, and histologic changes in liver and testes of paraquat-induced Wistar rats.","PeriodicalId":415591,"journal":{"name":"Japan Journal of Clinical & Medical Research","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128538686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation Between Transmitral Early and Late Diastolic Velocities Ratio and Ratio of Medial Mitral Annular Early and Late Tissue Doppler Velocities 经膜舒张早期和晚期速度比与二尖瓣内侧环早期和晚期组织多普勒速度比的相关性

Japan Journal of Clinical & Medical Research Pub Date : 2022-06-30 DOI: 10.47363/jjcmr/2022(2)135

D. Maisuradze

引用次数: 0

A Mini Review on New Drugs Approved in 2021 2021年获批新药迷你回顾

Japan Journal of Clinical & Medical Research Pub Date : 2022-04-30 DOI: 10.47363/jjcmr/2022(2)131

Akash Agnihotri, Saravana Kumar Ramasubbu

引用次数: 1

The Perception and Behavioral Attitude to Malaria of Non-parental Care-givers Living on an Atlantic Ocean Coastal Community in Nigeria: Paper 1 生活在尼日利亚大西洋沿岸社区的非亲代照顾者对疟疾的认知和行为态度:论文1

Japan Journal of Clinical & Medical Research Pub Date : 2022-04-30 DOI: 10.47363/jjcmr/2022(2)130

Bamgboye M Afolabi, Titilola M Afolabi

引用次数: 0

Diagnosis of CNS Lesions by CSF 脑脊液诊断中枢神经系统病变

Japan Journal of Clinical & Medical Research Pub Date : 2022-04-30 DOI: 10.47363/jjcmr/2022(2)129

Frank Y. Shan, Dong-xia Feng

引用次数: 0

Rac1 Rich Proline are OPA1 Flux Influencer for PLCs and IFNs Synthesis where Immune and Toxicity Due Deficiency in Synthetase and in Proline Synthesis 富含脯氨酸的Rac1是plc和ifn合成的OPA1通量影响因子，由于合成酶和脯氨酸合成缺乏免疫和毒性

Japan Journal of Clinical & Medical Research Pub Date : 2022-04-30 DOI: 10.47363/jjcmr/2022(2)132

Ashraf Marzouk El Tantawi

{"title":"Rac1 Rich Proline are OPA1 Flux Influencer for PLCs and IFNs Synthesis where Immune and Toxicity Due Deficiency in Synthetase and in Proline Synthesis","authors":"Ashraf Marzouk El Tantawi","doi":"10.47363/jjcmr/2022(2)132","DOIUrl":"https://doi.org/10.47363/jjcmr/2022(2)132","url":null,"abstract":"Rac1 is basis for ATPase, ribosomes repairs, Gactin activities, and regulating fatty Acyl-COA productions (upon OPA1 function) which are main for epidermal growth factor “EGF” synthesis and for both PLCs and IFNs synthesis. Rac1 basically are S6K rich Proline and hydrophobic amino acids that each amino acid especially Proline characterize Rac1 for scpsific functions and activity for regulating specific anti-inflammatory cycles and specific anti-inflammatory growth, that Rac1 has the roles of acting on inflammatory sources for analyzing and producing long fatty chains which will follow the OPA1 oxidative function (which activated by GTPase which promoted by Rac1 active molecules ) for producing fatty Acyl-COAs isoforms which considered as GP-GTP isoforms Gp-GTP gamma, GP-GTP beta, and GP-GTP alpha isoforms where some said that GTPase has been analyzed to give Gp isoforms but GTPase has activated OPA1 enzymes which produced Gp-GTP nuclear isoforms upon effect on long fatty chains, that GP-GTP beta and alpha have the roles of promoting PLCs and IFNs isoforms for anti-inflammatory processes and for anti-inflammatory growth . That The Rho family Rac1-GTPase (Gp isoforms) mediates a variety of signal transduction processes leading to activation of NADPH oxidase, actin cytoskeleton reorganization and anti-inflammatory growth.","PeriodicalId":415591,"journal":{"name":"Japan Journal of Clinical & Medical Research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130326119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Examining the Role of Government Policies in Improving Healthcare Quality to the Aboriginal and Torres Strait Islander Communities in Australia: Rapid Review 审查政府政策在提高澳大利亚土著和托雷斯海峡岛民社区医疗保健质量方面的作用:快速审查

Japan Journal of Clinical & Medical Research Pub Date : 2022-02-28 DOI: 10.47363/jjcmr/2022(2)126

Mahmoud Al-Masaeed

{"title":"Examining the Role of Government Policies in Improving Healthcare Quality to the Aboriginal and Torres Strait Islander Communities in Australia: Rapid Review","authors":"Mahmoud Al-Masaeed","doi":"10.47363/jjcmr/2022(2)126","DOIUrl":"https://doi.org/10.47363/jjcmr/2022(2)126","url":null,"abstract":"Aim and Significance: The review examines the impact of Australian government policies on healthcare quality delivery to the minority communities of the aboriginal and Torres Strait Islander community within Australia. The focus is on the value and impacts of the policies, denoting their success and limitation areas. This is informed by the need to ensure equity for all in accessing healthcare services as a global healthcare provision sustainability goal. Methods: This review was based on a search of the existing secondary data that is publicly available. The analysis searched the Australian government website for its official healthcare policy publications and supporting peer reviews from the Google scholar, PubMed, Scopus, and Medline databases, respectively. The findings were analysed through the PRISMA model, and inclusion and exclusion criteria were applied to ensure findings relevance and alignment with the review aim. Findings and Conclusion: The review analysis established that the Australian government has enacted healthcare policies targeting the aboriginal and Torres Strait Islander community within Australia. Key areas of focus in enhancing healthcare quality for this target healthcare population were (i) improving healthcare access and (ii) enhancing healthcare affordability through cost reduction.","PeriodicalId":415591,"journal":{"name":"Japan Journal of Clinical & Medical Research","volume":"12 18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125640122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Pathogen Comamonas Testosteroni: A Case Report And Review of The Literature 罕见病原菌睾酮共胞菌1例报告及文献复习

Japan Journal of Clinical & Medical Research Pub Date : 2021-07-14 DOI: 10.21203/RS.3.RS-532104/V1

S. Buyukberber, I. Mumcuoglu, B. Ozbay, A. Aypak, B. Dinç

{"title":"A Rare Pathogen Comamonas Testosteroni: A Case Report And Review of The Literature","authors":"S. Buyukberber, I. Mumcuoglu, B. Ozbay, A. Aypak, B. Dinç","doi":"10.21203/RS.3.RS-532104/V1","DOIUrl":"https://doi.org/10.21203/RS.3.RS-532104/V1","url":null,"abstract":"\u0000 Comamonas testosteroni is a Gram- negative, aerobic, motile, non-spore-forming bacillus. It has not been recognized as a component of the endogenous human microflora. Due to its ability to survive in liquid environments, it can survive for a long time in a hospital environment and cause opportunistic infections. Although rare, C. testosteroni has been reported as a cause of cellulitis, peritonitis, endocarditis, meningitis, endophthalmitis, tenosynovitis, pneumonia and bacteremia. Here, we present a case of a 4-year-old girl who was operated on for persistent cloaca with C. testosteroni isolated in her urine culture. Identification studies were performed by MALDI-TOF MS (bioMerieux, France) mass spectrophotometer method. Antibiotic susceptibility tests were performed with the automatic device VITEK-2 Compact (bioMérieux, France). Microorganism was found susceptible to ceftazidime and ciprofloxacin; intermediate susceptible to meropenem and piperacillin / tazobactam and resistant to gentamicin, amikacin, imipenem and trimethoprim-sulfamethoxazole. With this case report, C. testosteroni was reported as the first cause of urinary tract infection in our country and the third in the world.","PeriodicalId":415591,"journal":{"name":"Japan Journal of Clinical & Medical Research","volume":"280 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127717788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Japan Journal of Clinical &amp; Medical Research最新文献

Japan Journal of Clinical & Medical Research最新文献