IP Indian Journal of Neurosciences最新文献_第10页

Dilemma in low-grade glioma surgery: Review of litreture and when to operate 低级别胶质瘤手术的困境:文献回顾和手术时机

IP Indian Journal of Neurosciences Pub Date : 2022-03-15 DOI: 10.18231/j.ijn.2022.003

Sanjay Sharma, Ritika Jain

{"title":"Dilemma in low-grade glioma surgery: Review of litreture and when to operate","authors":"Sanjay Sharma, Ritika Jain","doi":"10.18231/j.ijn.2022.003","DOIUrl":"https://doi.org/10.18231/j.ijn.2022.003","url":null,"abstract":"Diffuse low-grade gliomas (LGG) are tumours of the glial tissue, which are generally slow-growing, but have the potential to undergo anaplastic progression into more aggressive tumours. Diffuse low-grade gliomas (LGG) represent a heterogeneous group of primary brain tumour arising from supporting glial cells. The role of surgery in the management of human low- gliomas has been controversial. The current adjuvant therapies have facilitated treatment of patients, and have rendered neurosurgical removal without morbidity or mortality more commonplace than ever before. Here, we investigated the role of neurosurgery in the management of adults with low-grade gliomas. The management of low- grade glioma is one of the most controversial areas in clinical neuro-oncology. The concept of management of low-grade gliomas is not unitary but much more a composite of different challenges depending on the clinical presentation, signs, neuroradiology, perspectives of neurologists, the opinion of the neurosurgeon, and perhaps most importantly, the aspirations of the patient. It is true therefore that in many patients there will be a dilemma about what is considered optimal management since there is no good evidence base to underpin any single management. Even though there is substantial evidence which claims that surgery have a role to play in extending patient survival.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131027227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antenatelly detected hypothalamic hamartoma-A case report 产前检出下丘脑错构瘤1例

IP Indian Journal of Neurosciences Pub Date : 2022-03-15 DOI: 10.18231/j.ijn.2022.017

T. Kesavan, Neethu K K, Rabiya A

引用次数: 0

Measured flamboyance – A desideratum in post COVID era 衡量华丽——后COVID时代的渴望

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.047

A. Cherian

引用次数: 0

SUDEP in adults and children 成人和儿童的猝死症

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.048

A. Cherian, D. K P

{"title":"SUDEP in adults and children","authors":"A. Cherian, D. K P","doi":"10.18231/j.ijn.2021.048","DOIUrl":"https://doi.org/10.18231/j.ijn.2021.048","url":null,"abstract":"Sudden unexpected death in epilepsy (SUDEP) represents an important cause of death in patients with epilepsy and it exceeds the expected rate of sudden death in the general population by nearly 24 times. We searched the electronic databases (Cochrane, EMBASE, Scopus, Medline, Pubmed) for studies related to etiology and risk stratification of SUDEP including data on Takotsubo cardiomyopathy (TKC) following seizures resulting in death or near death.: SUDEP is more common among males in the fourth decade of life. Risk for SUDEP is increased by early onset of seizures, low IQ, generalised tonic clonic seizures, nocturnal seizures and seizure frequency. Nonadherance to antiepileptic medications, absence of therapeutic drug level monitoring, presence of neuropathological lesions on imaging and certain subgroups like Dravet syndrome increase its risk. The risk for premature death in patients undergoing temporal lobe resection for drug resistant epilepsy decreased over time but remained above the standard population. Prolonged postictal electroencephalographic suppression was a risk factor for SUDEP in patients with generalised seizures which may indicate a cerebral electrical shutdown. Documented ictal/postictal hypoventilation, laryngeal spasm and cardiac rhythm abnormalities prior to SUDEP may suggest central apnea, neurogenic pulmonary edema, cardiac arrhythmia, or a combination of the above as a cause. Seizure triggered TKC does not seem to play a major role in the pathogenesis of SUDEP.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125766124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guillain barre syndrome and its association with covid-19 infection – A clinical case series 格林巴利综合征及其与covid-19感染的关系——临床病例系列

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.060

Madhavi Karri, Deepa Jacob, Balakrishnan Ramasamy, S. Perumal

{"title":"Guillain barre syndrome and its association with covid-19 infection – A clinical case series","authors":"Madhavi Karri, Deepa Jacob, Balakrishnan Ramasamy, S. Perumal","doi":"10.18231/j.ijn.2021.060","DOIUrl":"https://doi.org/10.18231/j.ijn.2021.060","url":null,"abstract":"A novel coronavirus (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2). This pandemic has been globally alarming in the current period. Several neurological manifestations are reported occurring with the infection. Guillain barre syndrome (GBS) or acute onset inflammatory polyradiculoneuropathy has been among the frequent manifestations observed among them. To know the pattern and outcome of GBS in COVID-19 affected individuals. We have taken six individuals admitted with flaccid quadriparesis in the last two months. All were affected recently by COVID 19 infection, which RT PCR of the nasopharyngeal swab confirmed. The study participants have undergone nerve conduction studies and have been diagnosed with Guillain Barre syndrome using Brighton criteria. We did cerebrospinal fluid (CSF) analysis after admission. We initiated all patients on Intravenous immunoglobulin according to body weight (2g/kg divided over five days). We used the Barthel index score to assess the outcome of the individuals. We observed a mean duration of 18.25 days between the COVID-19 infection and the onset of symptoms. Apart from motor quadriparesis and sensory symptoms being in common, we also noticed cranial nerves and autonomic involvement. We made the diagnosis using the nerve conduction studies and Brighton criteria. After initiating intravenous immunoglobulin, all patients had a good outcome, and quality of life was better after two months of follow up. Guillain Barre syndrome is one of the neurological manifestations of COVID-19 and has a dramatic response with intravenous immunoglobulin and better outcome with treatment.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128187842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prevalence and burden of primary headache disorders among adults in rural villages of Bangalore District, South India: A community-based study 印度南部班加罗尔地区农村成年人原发性头痛疾病的患病率和负担:一项基于社区的研究

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.059

T. Mathew, Shweta Ajay, B. Goud, D. Shanbhag, Charles J Pallan, Priya Genevieve D'mello, Ryan Colaço, Sneha J. Andrade, Nidhin Varghese, S. John

{"title":"The prevalence and burden of primary headache disorders among adults in rural villages of Bangalore District, South India: A community-based study","authors":"T. Mathew, Shweta Ajay, B. Goud, D. Shanbhag, Charles J Pallan, Priya Genevieve D'mello, Ryan Colaço, Sneha J. Andrade, Nidhin Varghese, S. John","doi":"10.18231/j.ijn.2021.059","DOIUrl":"https://doi.org/10.18231/j.ijn.2021.059","url":null,"abstract":"The prevalence of primary headache disorders (PHDs) and their burden has been seldom studied in the rural community setting of a developing country. To study the prevalence of primary headache disorders and their burden in the rural community A door to door survey was done in seven rural villages under Mugalur sub centre area, Sarjapura Primary Health Centre and Anekal taluk, Bangalore district, Karnataka State, south India, for finding the prevalence and burden of PHDs. During the study period of three months, a total of 1255 people were screened in the seven villages. 13.1% (165/1255) of people suffered from PHDs. The population prevalence of migraine without aura was 8.84% (111/1255), tension type headache was 2.86% (36/1255) and chronic migraine was 1.43%(18/1255). The mean number of headache days for all the PHDs was 4.26 (±1.64) days. 66.1% of persons with headache reported minimal or infrequent impact of headache. Among various demographic variables, headache was significantly associated with the female gender and marital status. PHDs are prevalent in the rural communities of developing countries and need urgent attention of primary care physicians, community health departments, governmental agencies and policy makers.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121445536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Miller fisher syndrome – A rare complication of covid-19 infection 米勒-费舍尔综合征——一种罕见的covid-19感染并发症

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.061

Priyanshu Bansal, V. Sehgal, Lucky Bhalla, Shaifali Arora

引用次数: 2

Covid-19 induced optic neuritis – A case report Covid-19诱导视神经炎1例

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.062

Priyanshu Bansal, V. Sehgal, Lucky Bhalla, Shaifali Arora

引用次数: 2

Approach to an adult with an episode of seizure 接近一个癫痫发作的成年人

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.049

D. K P, A. Cherian

{"title":"Approach to an adult with an episode of seizure","authors":"D. K P, A. Cherian","doi":"10.18231/j.ijn.2021.049","DOIUrl":"https://doi.org/10.18231/j.ijn.2021.049","url":null,"abstract":"A patient with known epilepsy who has had a single, habitual seizure and whose mental status has returned to baseline need not be transported to the emergency department (ED) unless other injuries require so, whereas a patient with no history of epilepsy who has returned to baseline following a seizure should be evaluated. The evaluation should include basic biochemical parameters, toxicology screening and a brain imaging. One should investigate circumstances that may have precipitated a seizure, such as alcohol withdrawal, stimulant use, or head injury. Risk of recurrence of seizures is more likely in those with a history of significant brain injury or infection. If the patient has a normal magnetic resonance imaging (MRI) and electroencephalograph (EEG), the likelihood of a second seizure is approximately 1 in 3; if either test result is abnormal, the chances are approximately 1 in 2; if both are abnormal, the probability rises to 2 in 3. Computed tomography (CT) scan head is very useful in the evaluation of first seizure in infants less than six months of age. The clinical characteristics predictive of an abnormal CT scan for patients presenting with seizures were age less than 6 months or age greater than 65 years, history of cysticercosis, altered mentation, closed head injury, recent cerebrospinal fluid (CSF) shunt revision, malignancy, neurocutaneous disorder and seizures with focal onset or duration longer than 15 minutes. MRI has been shown to be superior to CT for the detection of cerebral lesions associated with epilepsy.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"526 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124952966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

GABA: A critical player for regulating synaptic plasticity and adult neurogenesis GABA:调节突触可塑性和成人神经发生的关键因素

IP Indian Journal of Neurosciences Pub Date : 2022-01-15 DOI: 10.18231/j.ijn.2021.050

Mamata Mishra, P. Seth

{"title":"GABA: A critical player for regulating synaptic plasticity and adult neurogenesis","authors":"Mamata Mishra, P. Seth","doi":"10.18231/j.ijn.2021.050","DOIUrl":"https://doi.org/10.18231/j.ijn.2021.050","url":null,"abstract":"During aging, the decrease of cognitive ability is believed to be the cause of age related neuronal damage and reduced proliferation and differentiation of adult-born neural precursor cells. To modulate the synaptic plasticity and adult neurogenesis, it is of immense importance to enhance the potential of resident neural stem cells of hippocampus and sub ventricular zone (SVZ). The necessity to restore brain functions is enormous in the neurodegenerative disease like Alzheimer, Parkinson diseases, stress induced cognitive dysfunction, depression and age-associated and HIV-associated dementia. As a pioneer transmitter, Gamma Amino Butaric Acid (GABA) influences the activity dependent adult neurogenesis and excites immature neurons in adult hippocampus. GABA holds the key for making adult immature neuron to mature functional neuron hence plays critical role in adult neurogenesis.This review aims to discuss about the spatio-temporal expression of various subunit of GABA-A receptor and how these subunits intimately modulates the synaptic plasticity. During developmental period GABAergic neurons mature at early stages and regulate overall neural activity much before the activity of glutamate. Not only during development but also during adult neurogenesis GABA plays a significant role in neurite outgrowth and establishing well network.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116172359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0