Sanus Medical Journal最新文献

D-Dimer Sebagai Salah Satu Parameter Perbaikan Klinis pada Kasus Covid-19 Gejala Berat D-Dimer是Covid-19病例的临床修复参数之一

Sanus Medical Journal Pub Date : 2022-11-30 DOI: 10.22236/sanus.v4i2.10039

Antin Trilaksmi, Martin

{"title":"D-Dimer Sebagai Salah Satu Parameter Perbaikan Klinis pada Kasus Covid-19 Gejala Berat","authors":"Antin Trilaksmi, Martin","doi":"10.22236/sanus.v4i2.10039","DOIUrl":"https://doi.org/10.22236/sanus.v4i2.10039","url":null,"abstract":"Background. Coronavirus Disease 2019 (COVID-19) has been a global pandemic since March 2020. The number of patients is massive and clinical symptoms vary from mild to severe symptoms. Several laboratory results showed abnormal values in Covid-19 patients, including an increase in the value of D-dimer. Elevated levels of D-dimer in COVID-19 patients are strongly associated with severity and increased mortality. We report a case of a severe symptomatic COVID-19 patient with high D dimer levels at the start of treatment and showing clinical improvement according to a decrease in D dimer levels.\u0000Methods. We treat and follow the clinical and laboratory developments of COVID-19 patients with severe symptoms from the time they enter the Intensive Care Unit (ICU) until they move to a regular ward.\u0000Results. A 53-year-old male patient diagnosed with viral pneumonia et causa covid-19 was admitted to the ICU with severe symptoms and high initial d-dimer levels (1,413 ug/ml). The patient received ventilator assistance and standard therapy according to the Covid 19 management protocol of the Ministry of Health of the Republic of Indonesia. Anticoagulation using heparin intravenously with a dose adjusted to the level of d dimer, aPTT, and clinical condition of the patient who is monitored regularly. The trend of d dimers decreased parallel to the decrease in C reactive protein (CRP) levels, increased lung gas exchange function was evaluated from the PaO2/Fio2 ratio (PF ratio) and the clinical improvement of the patients.\u0000Conclusion. D-dimer is closely related to the severity of covid 19 patients. D dimer can be used as one of the parameters of patient clinical improvement.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131646837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emfisema Subkutis sebagai Komplikasi pada Pasien Covid-19 dengan Penggunaan Ventilasi Mekanik 皮下肺气肿是Covid-19患者使用机械通风的并发症

Sanus Medical Journal Pub Date : 2022-11-30 DOI: 10.22236/sanus.v4i2.10388

Lira Panduwaty, Antin Trilaksmi, Ferdy Cipta

{"title":"Emfisema Subkutis sebagai Komplikasi pada Pasien Covid-19 dengan Penggunaan Ventilasi Mekanik","authors":"Lira Panduwaty, Antin Trilaksmi, Ferdy Cipta","doi":"10.22236/sanus.v4i2.10388","DOIUrl":"https://doi.org/10.22236/sanus.v4i2.10388","url":null,"abstract":"Background. The incidence of subcutaneous emphysema in patients with severe pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection has been in the spotlight recently. Subcutaneous emphysema is a rare complication. With the increasing prevalence of subcutaneous emphysema in patients with confirmed coronavirus disease (COVID-19), it is necessary to know what factors can cause this and how to treat it.\u0000Case Description. Two patients, a man and a woman aged 50 and 70 years, diagnosed with COVID-19, came to the Emergency Room (IGD) of Bunda Menteng General Hospital, Jakarta, with symptoms of acute respiratory distress syndrome (ARDS). Both patients experienced severe shortness of breath with a respiratory rate above 30 times per minute. Then the two patients were treated in the intensive care Unit (ICU) isolation room and required mechanical ventilation assistance. After 3-4 days of mechanical ventilation treatment, subcutaneous emphysema develops, characterized by subcutaneous crepitus. After chest x-rays were carried out in both patients, the results were subcutaneous emphysema and pneumomediastinum. Several invasive procedures have been performed, such as subcutaneous insertion of an intravenous cannula, mediastinoscopy, and chest tube insertion.\u0000Conclusion. Complications of subcutaneous emphysema in COVID-19 patients are rare and require further research to determine the cause, where the infection is still the focus. With this case report, it is hoped that clinicians will pay more attention to the initial clinical findings of subcutaneous emphysema to reduce even more severe complications such as pneumothorax.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128676719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Abdominal Case Report: Ruptured Ovarian Endometriotic Cyst Concurrent with Acute Appendicitis 急性腹部病例报告:卵巢子宫内膜异位囊肿破裂并发急性阑尾炎

Sanus Medical Journal Pub Date : 2022-11-30 DOI: 10.22236/sanus.v4i2.9939

Gupita Nareswari

引用次数: 0

Strategi Pemasaran pada Sistem Layanan Kesehatan 医疗保健系统的营销策略

Sanus Medical Journal Pub Date : 2022-11-30 DOI: 10.22236/sanus.v4i2.8062

Sidhi Laksono Purwowiyoto, Cattleya Ananda Vilda, Dionisius Indri Priyobodo, Ivana Raisa Cicilia

引用次数: 0

Pengaruh Pemakaian Masker Bedah dan Masker Kain pada Wajah 手术面罩和面膜对面部的影响

Sanus Medical Journal Pub Date : 2022-11-30 DOI: 10.22236/sanus.v4i2.10040

H. Sutanto, Ade Saroso, D. Setyaningrum, Florinda Ilona

引用次数: 0

Karakteristik Mutasi EGFR pada Pasien Kanker Paru Jenis Adenokarsinoma yang Diterapi dengan Tyrosien Kinase Inhibitor (TKI) di Rumah Sakit Paru Dr. H.A Rotinsulu Bandung 病毒性肾癌患者的EGFR突变特征

Sanus Medical Journal Pub Date : 2022-02-28 DOI: 10.22236/sanus.v3i1.8431

Desi Puspita, Vitri Dwi Astuti, Rina, Edi Sampurno

引用次数: 0

Rare Case of Metaplastic Breast Carcinoma with Squamous Differentiation in Young Female: A Case Report 年轻女性罕见的化生性乳腺癌伴鳞状分化1例

Sanus Medical Journal Pub Date : 2022-02-28 DOI: 10.22236/sanus.v3i1.8090

Rohana Agustina

{"title":"Rare Case of Metaplastic Breast Carcinoma with Squamous Differentiation in Young Female: A Case Report","authors":"Rohana Agustina","doi":"10.22236/sanus.v3i1.8090","DOIUrl":"https://doi.org/10.22236/sanus.v3i1.8090","url":null,"abstract":"Background. Metaplastic breast carcinoma is a very rare breast cancer, only about 0.2\"‘1% of all invasive breast carcinomas. The prognosis of these cancer is poor and aggressive, reported to have lower response rates to conventional adjuvant chemotherapy and a worse clinical outcome after chemotherapy than other forms triple\"‘negative breast carcinomas. Histopathologically, metaplastic breast carcinoma has distinct patterns with different outcomes. Among the types of metaplastic carcinoma, squamous cell, high grade spindle cell and high grade adenosquamous carcinoma are associated with the worst prognosis. We report one case of metaplastic breast carcinoma with squamous differentiation in young patient. \u0000Methods. We examined the breast tumor tissue of a female patient, evaluated the macroscopic and microscopic features and asked the patient about the clinical course of the disease. Inform consent was obtained from the patient for publication of this case report and accompanying images. \u0000Results. We reported a young female patient with final diagnosis of pathology Mixed Infiltrating Duct Carcinoma of No Special Type Grade 3 and Metaplastic Breast Carcinoma with Squamous Differentiation (30%) that has invaded fat tissue with Ductal Carcinoma Insitu of High Nuclear Grade 3 with basis of the operation is still positive for the tumor mass. Patients lost follow\"‘up and did not continue therapy. \u0000Conclusion. Morphology of metaplastic breast carcinoma are important factors influencing patient outcome. Early diagnosis and wide local excision of the squamous\"‘type metaplastic breast carcinoma mass can make a better prognosis.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126469012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Narrow distance inter-pregnancies increase the incidence of Post-Partum hemorrhage 短间隔妊娠增加了产后出血的发生率

Sanus Medical Journal Pub Date : 2022-02-28 DOI: 10.22236/sanus.v3i1.8569

Nadhira Farah Puspitasaria, Irmiya Rachmiyani

{"title":"Narrow distance inter-pregnancies increase the incidence of Post-Partum hemorrhage","authors":"Nadhira Farah Puspitasaria, Irmiya Rachmiyani","doi":"10.22236/sanus.v3i1.8569","DOIUrl":"https://doi.org/10.22236/sanus.v3i1.8569","url":null,"abstract":"Background and Aims. Maternal Mortality Rate (MMR) is the parameters of women's health status in community. The single most common cause of maternal mortality is obstetric haemorrhage, generally occurring postpartum. Most postpartum haemorrhage cases are caused by uterus atony, myometrium tonus loss, placenta retention, and clotting disorders. Short pregnancy intervals can cause threefolds of anaemia than normal pregnancy intervals. Pregnant women who suffer from anaemia has the possibility experiencing a postpartum bleeding caused by atonia uteri. This research aims to acknowledge the effect of narrow distance interpregnancy on a postpartum haemorrhage. \u0000Methods. This study uses an observational analytic study with a cross\"‘sectional design. The data used is secondary data of pregnant women based on medical record to calculate the distance of interpregnancy with the incidence of postpartum bleeding during childbirth at Budhi Asih General Hospital of East Jakarta. The inclusion criteria are women who underwent childbirth during 2017\"‘2018, multiparity, and postpartum women between 20\"‘35 years old. The exclusion criteria are women with a history of postpartum haemorrhages caused by placental retention, tear of the reproductive tract or blood coagulation), gemelli parturition, macrosomia, assisted childbirth, grande multiparity, induction childbirth, and dystocia. \u0000Results. The number of samples used in this study amounted to 111 people. Postpartum haemorrhage are significantly associated with short interpregnancy intervals (p=0,000). \u0000Conclusion. Narrower pregnancy interval will leads to postpartum haemorrhage. To prevent this, it is important to consider contraception utilization, to improve iron consumption for pregnant women, and to provide decent antenatal care.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"62 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120932318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Nyeri Kronik dalam Penurunan Fungsi kognitif 慢性疼痛对认知功能衰退的影响

Sanus Medical Journal Pub Date : 2022-02-28 DOI: 10.22236/sanus.v3i1.8525

Fahreza Arraisyi, Yudhisman Imran

{"title":"Pengaruh Nyeri Kronik dalam Penurunan Fungsi kognitif","authors":"Fahreza Arraisyi, Yudhisman Imran","doi":"10.22236/sanus.v3i1.8525","DOIUrl":"https://doi.org/10.22236/sanus.v3i1.8525","url":null,"abstract":"Nyeri merupakan gejala yang sering dikeluhkan masyarakat, Di Indonesia sendiri nyeri kronik adalah alasan paling umum pasien untuk berkunjung ke klinik rawat jalan. Nyeri kronik merujuk pada nyeri yang berkelanjutan lebih dari tiga bulan. Penyebab nyeri kronik tersering adalah nyeri punggung bawah kronik, diikuti oleh nyeri leher kronik, migrain, osteoartritis, gangguan muskuloskeletal lainnya, nyeri kepala akibat penggunaan obat yang berlebihan, dan polineuropati diabetikum \u0000Prevalensi nyeri kronik meningkat seiring dengan bertambahnya usia. Nyeri kronik merupakan masalah kesehatan di seluruh dunia, mempengaruhi 19% orang dewasa Eropa dan 20,4% di Amerika Serikat. \u0000Keluhan subjektif pasien nyeri kronik dari berbagai penelitian menunjukkan bahwa nyeri kronik dikaitkan dengan defisit kognitif. Pada pasien nyeri kronik terjadi interaksi antara nyeri dan fungsi kognitif secara lebih kompleks. Hal ini menyebabkan gangguan fungsi otak yang berkembang mengikuti progresi dari nyeri kronik. Pada nyeri kronik dijumpai aktifitas neuron yang berlebihan, disfungsi jaringan dan pengurangan volume grey matter. Kehilangan grey matter dijumpai dalam amigdala, korteks entorinal girus hipokampus, girus singulata anterior, thalamus dan insula. \u0000Hubungan antara nyeri kronik dan penurunan fungsi kognitif selayaknya diperhatikan lebih lanjut dikarenakan memiliki implikasi terhadap fungsi dan kualitas hidup individu. Berbagai penelitian menunjukkan hasil hubungan signifikan terbalik penurunan dari atensi, memori, proses informasi dan fungsi eksekutif pada pasien dengan nyeri kronik.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"141 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120986189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laporan Kasus Karsinoma Sel Skuamosa yang Berkembang dari Papiloma Tipe Inverted Sinonasal pada Pekerja Pabrik Cermin 鳞状细胞癌病例报告，由乳头状瘤病毒及其同源型反射镜工人发展而来

Sanus Medical Journal Pub Date : 2022-02-28 DOI: 10.22236/sanus.v3i1.8103

Fety Riani, Ita Marlita Sari

{"title":"Laporan Kasus Karsinoma Sel Skuamosa yang Berkembang dari Papiloma Tipe Inverted Sinonasal pada Pekerja Pabrik Cermin","authors":"Fety Riani, Ita Marlita Sari","doi":"10.22236/sanus.v3i1.8103","DOIUrl":"https://doi.org/10.22236/sanus.v3i1.8103","url":null,"abstract":"Background. Sinonasal inverted (PI) papilloma is a benign tumor of the mucosal epithelium of the nasal cavity and paranasal sinuses with an endophytic growth pattern. PI is more common in men in the fifth and sixth decades of life. These tumors have local aggressive behavior, high recurrence rates, and can undergo malignant transformation. Squamous cell carcinoma (SCC) is the most common malignancy developed from sinonasal PI. SSC developed from PI (KSS/PI) is related to exposure in the work environment. \u0000Methods. We report a sinonasal SCC/PI case by describing the clinical manifestations, radiological features, and histopathological features of a young male patient who was a non\"‘smoker mirror\"‘making factory worker. \u0000Results. Clinical manifestations of pain, epistaxis, and proptosis in patients suggest malignancy. Computed Tomography (CT) results showed lesions of the nasal cavity and paranasal sinuses with bone destruction and expansion of the mass to the intracranial point of the aggressive behavior of the tumor. Microscopic histopathological examination revealed endophytic squamous epithelial growth characteristic of an inverted papilloma accompanied by cell atypia, invasive components, connective tissue desmoplasia, and keratin pearls, suggesting a well\"‘differentiated keratinized squamous cell carcinoma that developed from the sinonasal inverted papilloma. Exposure to dust in the work environment is related to malignancy in this patient. \u0000Conclusion. Support of clinical and radiological data, adequate sampling, and identification of malignancy morphology routinely on histopathological examination is critical to avoid misdiagnosis of sinonasal SCC/PI. A complete history directed at extracting risk factors can add value in establishing a diagnosis.","PeriodicalId":414987,"journal":{"name":"Sanus Medical Journal","volume":"61 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120886284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0