{"title":"Homecare and Disease Prevention: Reviewing a Decade of Evolution - Privacy Still the Biggest Hurdle","authors":"L. Kun","doi":"10.1109/IEMBS.2006.259457","DOIUrl":"https://doi.org/10.1109/IEMBS.2006.259457","url":null,"abstract":"Over a decade ago, while at the Agency for Health Care Policy and Research (AHCPR), now known as the Agency for Health Research and Quality (AHRQ), a vision was created by the author that projected two different concepts. One was the use of telemedicine in a homecare environment (in urban, suburban and rural areas) to offer particularly to the elderly population, suffering from a number of chronic conditions an environment which would allow to improve the quality of services while decreasing the costs of the (then and projected) \"current\" system. The second theme involved the potential use of genetic-related discoveries with personal health records for disease prevention purposes. While the homecare - telemedicine environment for the elderly with chronic diseases (has and) is evolving, the outcomes (cost and medical effectiveness) are not completely clear. The result is that what may be cost-effective in one country may not be in another one. The second premise, which involves the use of electronic health records, genetic discovery and intelligent agents, has moved much slower (if at all) than anticipated. In the US, at least, most of the barriers have been related to fears of privacy breaches. The combinations of Radio, Television, Computers and Telephones have become increasingly complex systems. These systems allow us to do a variety of actions that include: tele-banking, e commerce, tele-education, tele-work, tele-health, tele shopping, entertainment on demand, etc. In other words a family could stay home, get the food and water delivered, as well as any product bought from any store. While kids or adults could take courses at a distance, others in the family could tele-commute (i.e., work from home). A health care worker could visit any member of the family, or the family member could decide to visit specialist because of a specific condition/symptom or circumstance. So far, very few of these segments are interconnected and therefore most of these applications exist as silos. For example, many cable or satellite TV services have bidirectional communications. The services they provide today are multiple but mainly they have expanded the entertainment industry. The combination could result in a very powerful tool for the 21 century. The constant advancement in the areas of science and technology will allow us to reach new heights by helping humanity deal more effectively both medically and economically with all these diseases. A major challenge that we need to resolve is securing the privacy of the personal information","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114700586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Computational Biology and Bioinformatics\"","authors":"J. Jasinski","doi":"10.1109/IEMBS.2006.259775","DOIUrl":"https://doi.org/10.1109/IEMBS.2006.259775","url":null,"abstract":"I will discuss the current state of progress in high performance computing, biomolecular simulation and algorithms as we are applying them to understanding a range of problems in the use of information technology to understand biological systems. Examples will include the use of pattern discovery algorithms to understand gene expression, the use of massively parallel supercomputing capabilities made available by the Blue Gene architecture to probe the dynamics of protein folding and trans membrane proteins and how this work will impact the translation of basic science into clinical research and ultimately into clinical practice.","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130762089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The measurement technique of human's bio-signals","authors":"Y. Saeki, K. Takamura, K. Magatani","doi":"10.1109/SSRR.2005.1501235","DOIUrl":"https://doi.org/10.1109/SSRR.2005.1501235","url":null,"abstract":"A disaster like a big earthquake usually brings many destroyed buildings and many sufferers are generated in the disaster area. In this situation, sometimes a rescue person encounters a second disaster. This is the big problem to rescue sufferers. In order to avoid a second disaster, many kind of rescue robots are being developed. These robots can find sufferers and rescue them. However, they cannot measure the sufferer's condition at the disaster area. If the sufferer's condition becomes clear before rescue, the rescue efficiency will improve. Therefore, we are developing a rescue robot that can measure some vital signs of sufferer and send measured data to the medical doctor who is in safety place. In this paper, we will describe about a developed method that can measure the pulse and the arterial blood oxygen saturation degree (SPO2) by easy way. We think that these methods will be powerful and useful to rescue sufferers","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114421658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Pouponneau, L. Yahia, Y. Merhi, L. Epure, S. Martel
{"title":"Biocompatibility of Candidate Materials for the Realization of Medical Microdevices","authors":"P. Pouponneau, L. Yahia, Y. Merhi, L. Epure, S. Martel","doi":"10.1109/IEMBS.2006.260061","DOIUrl":"https://doi.org/10.1109/IEMBS.2006.260061","url":null,"abstract":"The propulsion of ferromagnetic micro-carriers in the blood vessels by magnetic gradients generated from a magnetic resonance imaging (MRI) system is of special interest for targeted interventions such as chemotherapy or chemo-embolization. As such, Fe-Co alloys for its highest magnetization saturation, and single crystal Ni-Mn-Ga powder and Terfenol-D for their deformation in magnetic field are evaluated for their biocompatibility. The toxicity of these materials is evaluated with MTT cell viability tests. The tests show that Fe-Co (Permendur and Vacoflux 17) alloys are toxic within 24 hours while the single crystal Ni-Mn-Ga powder becomes toxic after 48 hours. The Terfenol-D, despite its high degradation, has 90% cell viability after 72 hours. These results indicate that such candidate materials to be considered in untethered micro-carriers or devices in the blood vessels, would require, depending upon the time spent in the blood vessels, further processes to be viable for such applications","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"2023 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133191003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statistically Rigorous Human Movement Onset Detection with the Maximal Information Redundancy Criterion","authors":"G. Van Dijck, M. V. Van Hulle, J. Van Vaerenbergh","doi":"10.1109/iembs.2006.4397946","DOIUrl":"https://doi.org/10.1109/iembs.2006.4397946","url":null,"abstract":"Stroke patients have a decreased ability in performing activity of daily living (ADL) tasks such as in \"drinking a glass of water\", \"lifting a bag\", \"turning a key\" and so on. Sensorimotor force and torque measurements from patients performing these standardized ADL tasks are hypothesized to give quantitative information about the recovery process. Parts of the force/torque measurements contain useful information, when related to the initiation of the movement during ADL tasks. Here we address the challenging problem of automatically extracting the movement initiation from these force/torque measurements. We will adopt a machine learning approach which relies on the statistically rigorous maximal information redundancy (MIR) criterion. This assumes that movement initiation parts of the signals are characterized by an increased redundancy in the signal. A thorough evaluation of the criterion shows that the accuracy of the criterion in movement onset detection is close to that of clinical experts","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123406561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Soluble CD40L Versus Myocyte Enhancer Factor: Predicting a Prominent Marker For Cardiovascular Disease","authors":"C.H. de Trad","doi":"10.1109/iembs.2006.4397748","DOIUrl":"https://doi.org/10.1109/iembs.2006.4397748","url":null,"abstract":"Atherosclerosis (ACS) has set off the innovation of molecular markers measured in plasma or serum, and used for the identification of individuals at high risk of Coronary Heart Disease (CHD). In an attempt to improve cardiovascular risk prediction, considerable interest is focused on inflammatory biomarkers including Interleukin (IL)-6, Phospholamban (PLB), Myocyte enhancer factor 2A (MEF2A), and Soluble CD40 ligand. In this paper, signal-processing techniques predicted the characteristic frequencies of the above-mentioned proteins, and common binding sites. The CD40L characteristic frequency, 0.3555plusmn0.0001, is correlated with Protease inhibitors and the second peak, 0.4531plusmn0.0009, is closely related to Fgfs. This study also revealed that for MEF2A, the characteristic frequency, 0.0488plusmn0.0001, is specific for enhancers DNA regulating sequences. The remaining frequencies, 0.3672 plusmn0.0001 and 0.4648plusmn0.0002, are characteristic of the Myocyte Protease inhibiting activity and SOS operator function. Furthermore, clinical data suggested that the increased levels of CD40L reliably identify the subgroup of patients with ACS who are at highest risk for cardiac events. It is suggested that CD40L is a most prominent candidate for early detection of cardiac disease","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131750079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hybrid Feature Subset Selection for the Quantitative Assessment of Skills of Stroke Patients in Activity of Daily Living Tasks","authors":"G. Van Dijck, M. V. Van Hulle, J. Van Vaerenbergh","doi":"10.1109/iembs.2006.4398750","DOIUrl":"https://doi.org/10.1109/iembs.2006.4398750","url":null,"abstract":"Stroke patients have a decreased ability in performing activity of daily living (ADL) tasks such as in `drinking a glass of water', `turning a key', `picking up a spoon', `lifting a bag', `reaching a bottle' and `lifting and carrying a bottle'. These tasks can be quantified by measuring forces and torques exerted on the objects. However, the resulting force and torque time series represent information at a very low level of abstraction and don't inform clinicians what really distinguishes patients from normal controls in performing these tasks. We conduct an extensive quantitative analysis of these tasks and derive interesting features from the time signals that characterize the differences in behavior between patients and normal controls. We show that `drinking a glass' and `turning a key' are the most discriminative tasks; furthermore we show that the ability or disability to synchronize the thumb and the middle finger is one of the most important features","PeriodicalId":414051,"journal":{"name":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114605669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}