{"title":"Investigation of CMV and Rubella Seroprevalence and Age Related Distribution in Pregnant Women","authors":"Y. Gülseren, F. E. Taşbent, M. Özdemir","doi":"10.5222/tmcd.2019.154","DOIUrl":"https://doi.org/10.5222/tmcd.2019.154","url":null,"abstract":"","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133423254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Distribution and Antimicrobial Susceptibilities of Members of Enterobacterales Isolated from Blood Cultures in a University Hospital","authors":"H. Mirza, B. Sancak","doi":"10.5222/tmcd.2021.96658","DOIUrl":"https://doi.org/10.5222/tmcd.2021.96658","url":null,"abstract":"Objective: Members of Enterobacterales can cause various diseases in humans. The objective of this study was to determine the genus/species distribution and antimicrobial susceptibilities of Enterobacterales isolated from blood cultures in Central Laboratory of Hacettepe University Hospital. Method: Enterobacterales isolated from blood between July-2014 and April-2018 were included in the study. MALDI-TOF MS was used for the identification of isolates. Antimicrobial susceptibilities were determined with automated system (VITEK 2 Compact for the isolates between 2014 and 2018; BD Phoenix for the isolates in 2018) and disk diffusion method. Results of antimicrobial susceptibility testing were interpreted according to EUCAST breakpoints. Results: In total, 1765 isolates belonging to the order Enterobacterales were isolated from blood cultures. The most common microorganisms were Escherichia coli (47.6%), Klebsiella (34.1%), Enterobacter (6%), Proteus (4.4%) and Serratia spp. (3.5%), respectively. The remaining isolates included Salmonella, Citrobacter, M. morganii, Pantoea, Raoultella and Providencia spp. The lowest resistance rates among E. coli, Klebsiella and Enterobacter spp. isolates were observed against meropenem and amikacin. However, 21.1% of Klebsiella isolates were resistant to meropenem. The most active antimicrobials against Proteus isolates were piperacillintazobactam and meropenem. Resistance was not observed against piperacillin-tazobactam and meropenem among Proteus isolates. The most active antimicrobial against Serratia isolates was trimethoprim/ sulfamethoxazole with a resistance rate of 0%. Resistance was not noted against ampicillin and trimethoprim/ sulfamethoxazole among Salmonella isolates, whereas 26.1% of isolates were resistant to ciprofloxacin. All Citrobacter isolates were susceptible to meropenem, amikacin and cefepime. Conclusion: Findings of our study may guide the selection of proper antimicrobials for the treatment of bacteremia caused by Enterobacterales. Furthermore, this study provides important epidemiological information regarding the distribution of members of Enterobacterales causing bacteremia.","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"23 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115633436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. F. Şenol, P. Öner, Özlem Aytaç, Altay Babacan, Z. Toraman
{"title":"The Role of Parasitic and Viral Agents in Gastrointestinal Infections","authors":"F. F. Şenol, P. Öner, Özlem Aytaç, Altay Babacan, Z. Toraman","doi":"10.54453/tmcd.2022.53824","DOIUrl":"https://doi.org/10.54453/tmcd.2022.53824","url":null,"abstract":"","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"68 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126108675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harun Ağca, B. Ener, I. Saglik, E. Yılmaz, E. Kazak
{"title":"Retrospective Evaluation of Hepatitis C Virus Genotypes","authors":"Harun Ağca, B. Ener, I. Saglik, E. Yılmaz, E. Kazak","doi":"10.5222/tmcd.2021.32154","DOIUrl":"https://doi.org/10.5222/tmcd.2021.32154","url":null,"abstract":"","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127325935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esra Tuba Demir, Merve Aydın Terzioğlu, Mehmet Kulhan, Aytekin Çıkman, Barış Gülhan, N.Gözde Kulhan, Ilyas Sayar, Y. Arslan, Cuma Mertoğlu
{"title":"Serviks Dokularında HPV DNA Pozitifliği ve Osteopontin Düzeyi Arasındaki İlişkinin Araştırılması","authors":"Esra Tuba Demir, Merve Aydın Terzioğlu, Mehmet Kulhan, Aytekin Çıkman, Barış Gülhan, N.Gözde Kulhan, Ilyas Sayar, Y. Arslan, Cuma Mertoğlu","doi":"10.54453/tmcd.2022.28247","DOIUrl":"https://doi.org/10.54453/tmcd.2022.28247","url":null,"abstract":"Objective: This study aimed to investigate the osteopontin levels in HPV-positive and HPV-negative cervical tissues and evaluate the clinical significance of osteopontin as a prognostic biomarker. Methods: A total of 82 individuals admitted to the outpatient clinic of Obstetrics and Gynecology Department of Erzincan Binali Yıldırım University, Mengücek Gazi Training and Research Hospital in Turkey and underwent cervical cancer screening between June 2015 and April 2017 were included in the study. Cervicovaginal swabs were collected according to the standard procedure. A slide for traditional Pap cytology was prepared and stained according to standard protocols, and the results were categorized according to the 2004 Bethesda classification system. All cervical specimens were analyzed using the Digene® HC2 High-Risk HPV DNA Kit. Genotyping was performed on the samples with HPV DNA positivity with the Clark kit. Osteopontin levels of 41 HPV positive patients and 41 HPV negative control were investigated in tissue samples with an ELISA kit. Results: The osteopontin levels were found to be 31.55 ± 7.11 ng/ml and 28.81 ± 5.44 ng/ml in the study and control groups, respectively, which indicated a statistically significant difference between the groups (p=0.048). There was no statistically significant difference between the osteopontin level and age, delivery method, history of disease, surgical method, HPV type, preoperative and postoperative pathology, gravida and parity (p>0.05). Conclusion: The detection of cervical intraepithelial neoplasia in only five of 41 HPV-positive patients constitutes a limitation for this study. Although the level of osteopontin was high in HPV-positive patients, further studies with more cervical intraepithelial neoplasia cases are required.","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130493172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibiotic Resistance Profile of Stenotrophomonas maltophilia Infections with Limited Antibiotic Options","authors":"Gokce Aslan, F. E. Taşbent, M. Doğan","doi":"10.5222/tmcd.2021.26817","DOIUrl":"https://doi.org/10.5222/tmcd.2021.26817","url":null,"abstract":"Objective: Stenotrophomonas maltophilia is an opportunistic pathogen that frequently causes nosocomial infections in recent years. It is generally isolated from respiratory tract samples, blood, urine and drainage materials. Due to multiple antibiotic resistance, a limited number of antibiotics are used in the treatment of these infections. The aim of this study is to investigate the antibiotic resistance status and risk factors in isolated S. maltophilia strains. Method: Diversity and antibiotic susceptibility levels of S. maltophilia strains isolated from various clinical samples between January 2018 and June 2020 were examined using conventional methods and VITEK2 automated system. Demographic and diagnostic data of the patients were retrieved from the hospital’s data base to identify the risk factors of infection. Results: Of the 300 strains examined, 46% were isolated from intensive care units, 35.3% from patients hospitalized in other clinics, and 18.7% from outpatient clinic patients. It was observed that 64 (21.3%) of 300 patients were immunosuppressed. Trimethoprim-sulfamethoxazole resistance was 1.3% and levofloxacin resistance was 0.7%. Conclusion: Resistance rates were found to be lower than the literature data in the study. It was concluded that hospitalization in the intensive care unit and immunosuppression are important risk factors for S. maltophilia infections.","PeriodicalId":413797,"journal":{"name":"Türk Mikrobiyoloji Cemiyeti Dergisi","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126470682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}