American International Journal of Biology and Life Sciences最新文献

{"title":"BIOCHEMICAL CHANGES IN THE BLOOD OF CLARIAS GARIEPINUS JUVENILES FED WITH POULTRY WASTE","authors":"","doi":"10.46545/aijbls.v5i1.304","DOIUrl":"https://doi.org/10.46545/aijbls.v5i1.304","url":null,"abstract":"Artificial Nutrition is one of the most important means of boosting production in fish farming and maximizing the cost of feeding, effectively increasing profitability in fish production. This study evaluates the effect of poultry waste meal on the serum, kidney and liver of Clarias gariepinus. After acclimatization, the fish samples were grouped into groups 1, G1, fed with poultry waste and group 2, G2, with Coppens feed. The result showed a significantly higher difference (P > 0.05) in the mean serum composition for Fish fed with poultry waste for Aspartate Amino Transferase, A.S.T. (69.50±1.05), Alanine Amino Transferase, A.L.T. (69.95±1.07), Alkaline Phosphate, A.L.P. (69.10±1.31) compared to that of those fed with Coppens feed A.S.T. (54.87±1.47); A.L.T. (59.67±1.53); A.L.P. (56.47±0.50) respectively. High-density lipoprotein, HDL was significantly (P > 0.05) higher in C. gariepinus juveniles fed with poultry Coppens (71.07±1.17) than those provided with poultry waste (63.13±0.93). Alternately, Low-density lipoprotein, LDL, was significantly higher (P > 0.05) in Fish fed with poultry waste (81.33±0.93) than those provided with Coppens (74.17±1.08). Triglyceride was considerably higher in C. gariepinus juveniles fed with poultry waste (81.33±0.93) than in C. gariepinus juveniles fed with Coppens (74.17±1.08). The composition of Total Cholesterol in both experimental Fish is 86.6±0.60 for C. gariepinus juveniles fed with Coppens and 94.27±1.62 for C. gariepinus juveniles fed with poultry waste. The mean biochemical composition of the liver of C. gariepinus juvenile fed poultry waste showed a higher significant difference (P > 0.05) for A.S.T. (75.77±0.72), A.L.T. (60.17±0.12), A.L.P. (61.40±1.48), LDL (77.03±1.21), Triglyceride (77.03±0.93) and Total Cholesterol (68.87±0.46) than those fed with Coppens feed although HDL (78.00±1.14) was significantly higher in those provided with Coppens than those fed with poultry waste (59.73 ±1.07) while for the kidney A.S.T. (51.27±1.08), A.L.T. (47.77±0.87), A.L.P. (69.10±1.31), LDL (81.33±0.93) and Triglyceride (70.30±1.25) had a significantly higher difference (P > 0.05) than that C. gariepinus fed poultry waste A.S.T. (46.20±0.35), A.L.T. (39.33±1.15), A.L.P. (43.03±11.58), LDL (74.17±1.08) and Triglyceride (67.83±1.19) except HDL (71.07±1.17) which was significantly higher in Coppens fed Fish than those provided with poultry waste (63..13±0.93). An increase in biochemical composition observed in this study suggests a disruption in the metabolism of the fish juveniles fed with poultry waste. Therefore, poultry waste should not be depended on solely as fish feed for Clarias gariepinus.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IL-10 AND IL-35 AS INFLAMMATION REGULATORS IN PATIENTS WITH ALLERGIC RHINITIS AND MILD ATOPIC ASTHMA","authors":"Dr. Kremena Naydenova, A. Mihova, A. Kukov, Dr. Tsvetelina V. Velikova","doi":"10.46545/aijbls.v4i1.229","DOIUrl":"https://doi.org/10.46545/aijbls.v4i1.229","url":null,"abstract":"Background. Significantly less is known about the immunoregulative cytokines, especially in allergic airway disease. This study aims to present the involvement of IL-35 and IL-10 in patients with allergic rhinitis (AR) and allergic bronchial asthma (BA). Methodology. The study comprised 71 patients –AR, patients with concomitant AR and mild atopic BA, and healthy controls (HC). We examined the serum levels of IL-35 and IL-10, along with other instrumental examinations, between March and September 2021. Findings. Levels of the regulatory cytokines IL-35 and IL-10 were significantly lower in patients than in HC (87.19±11.90 vs. 96.12±1.79 pg/ml; and 30.26±17.55 vs. 111.56±65.03 pg/ml, respectively). Furthermore, threefold higher serum IL-10 levels were found in healthy subjects compared to patients (p = 0.006). No difference in the levels of interleukins was found between the studied groups. Conclusions. Our results indicate that elevated IL-35 and IL-10 may play an essential role in reducing the activity of underlying allergic inflammation in allergic respiratory diseases, although no difference in the levels of the studied cytokines was found between the different groups of patients. Therefore, we can speculate that the immunosuppressive cytokines IL-35 and IL-10 were involved in maintaining the healthy state of no inflammation.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125235321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HEALTH RISK MANAGEMENT IN KINDERGARTENS, SCHOOLS AND UNIVERSITIES, DURING COVID-19 PANDEMIC: A HEURISTIC FRAMEWORK","authors":"Latchezar P. Tomov, Dr. Tsvetelina V. Velikova, Dr. Hristiana M. Batselova","doi":"10.46545/aijbls.v3i1.207","DOIUrl":"https://doi.org/10.46545/aijbls.v3i1.207","url":null,"abstract":"The SARS-COV-2 pandemic, causing COVID-19 had a specific pattern of spread in Bulgaria during several waves from 15.06.2020 to 31.03.2021. The measures, which the health authorities took to prevent the spread in the kindergarten and schools, combined with several other factors, specific for Bulgaria made them the main driver of the pandemic. In this article we propose heuristic framework as a strategy for health risk management, based on the properties of the virus and the properties of children’s immune system.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134131845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STUDY OF SOME ASPECTS OF IL-5 ROLE IN THE ALLERGIC RESPIRATORY PATHOLOGY-ALLERGIC RHINITIS AND ASSOCIATED BRONCHIAL ASTHMA","authors":"Dr. Kremena Naydenova, Dr. Vasil Dimitrov, Dr. Tsvetelina V. Velikova","doi":"10.46545/aijbls.v3i1.315","DOIUrl":"https://doi.org/10.46545/aijbls.v3i1.315","url":null,"abstract":"Background: A lot of evidence exists on the relationship between the upper and lower respiratory airways based on epidemiological, clinical, and pathophysiological levels. However, new aspects of allergic inflammation and released cytokines play a crucial role in this interaction. This study aims to explore the role and involvement of IL-5 in patients with allergic rhinitis (AR) and newly diagnosed allergic bronchial asthma (BA) with a mild course, manifested after many years of previous persistent AR. Methods: This prospective study included 67 patients with allergic inflammation of the upper respiratory airways, manifested by AR, and involvement of the lower airways, clinically presented as mild atopic BA, recruited between 2020 and 2021. Results: AR patients were 35 (40.23%), and patients with a combination of AR and newly diagnosed BA - 32 (36.78%). Twenty healthy controls (22.99%) were also included. The most common type of sensitization was to grass pollen 43 (64%) and tree pollen - birch 32 (48%). We did not find significant differences between the serum levels of healthy individuals and patients included in the study. No associations between the IL-5 levels","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"310 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132033519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMMUNE PROPERTIES IN THE PRODUCTED RECOMBINANT SIP YOUNG 6 HIS PROTEIN FROM THE SEA STAR IGKAPPA GENE THROUGH HEK 293 EBNA CELLS REVEALING AGAINST SPIKE-RBD PROTEIN AND HRP ONE CHANGES IN SEA STAR GENE EXPRESSION?","authors":"Michel Leclerc","doi":"10.46545/aijbls.v3i1.309","DOIUrl":"https://doi.org/10.46545/aijbls.v3i1.309","url":null,"abstract":"In 2014 we have isolated and cloned the sea star Igkappa gene which induced an anti-HRP primitive invertebrate antibody. We attempt, in the present work, to produce a SIP Young 6 His protein through HeK 293 EBNA cells after Igkappa gene cloning. This protein bound HRP by the use of Escherichia coli as vector of cloning but not HRP with HeK cells as vector. Is there changes in sea star IGKappa gene expression? We notice also that the SARS-CoV-2-SPIKE RBD Protein didn’t bind to SIP Young 6 His protein when compared to HRP.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"32 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132144022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SOCIO-CULTURAL BINOCULARS VIEW OF TELEMEDICINE IN SUB-SAHARAN AFRICA: POTENCY, PROSPECT, DEFECT AND DANGER","authors":"Caroline Okumdi Muoghalu Senior Lecturer, Sunday Olutayo, Fakunle Online Instructor, PhD Student","doi":"10.46545/aijbls.v3i1.308","DOIUrl":"https://doi.org/10.46545/aijbls.v3i1.308","url":null,"abstract":"Sub-Saharan Africa has experienced unprecedented technological advancement, just like several other regions of the world. This improvement in technology lends credence to the proliferation of android mobile phones, laptops computers and the Internet facilities that enhance interaction on the social media which in turn generates momentous alterations in the ways the residents of the region construct their daily lives. From epidemiological perspective as well as the viewpoint of change and development, via these information technologies, rendering health-related care and services to the residents in the remote places of the region and gaining access to vital information that prompts prevention and control of diseases are now feasible unlike before the advancement. Therefore, telemedicine symbolizes a health innovation in the region. In the light of this, this paper systematically reviewed the extent to which telemedicine has gained acceptance among the residents of the region; and the socio-cultural factors and practices that promote and decelerate the general acceptance of telemedicine in the region. To accomplish the objective, the review was done meta-analytically and meta-synthetically to explore recent relevant studies. The paper discovered that reduction in the cost of gaining access to health information, harnessing online health and medical services, are among the benefits derived from telemedicine while fake online information, impoverished network service delivery, financial incapacity, theft, technical faults, underutilization of the technology devices and cyber-crime are among the factors that militate against wide acceptance of telemedicine in the region.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133499576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Potential of Morinda Lucida and Psidium Guajava Extracts and Actions Against Paracetamol- Induced Kidney and Liver Injuries in Rats","authors":"F. Akindele, Fredrick O. Obi","doi":"10.46545/AIJBLS.V2I1.141","DOIUrl":"https://doi.org/10.46545/AIJBLS.V2I1.141","url":null,"abstract":"Antioxidant agents of plants origin have continued to attract interest because of the potential they hold in the maintenance of human health accompany with their minimal side effects. The present study sought to evaluate the comparative free radical scavenging activities of ethanol extracts of air dried Morinda lucida leaves (EMLL) and Psidium guajava leaves (EPGL) by measuring their ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, nitric oxide (NOˉ) radical, 2,2 azinobis-( 3-ethylbenzothiazoline-6-sulfonic acid) (ABTS*), and inhibit lipid peroxidation (LPO). Antioxidant activities of the extracts were also determined in the plasma of the rats fed with the extracts by assaying for antiradical activity against DPPH and NO radicals in vitro. In vivo antioxidant effects of the extracts were also evaluated in paracetamol treated rats. Twenty rats were randomly divided into four groups for this study. Group 1 received normal feed as control, group 2 received 14.30mg/kg b.w of paracetamol by gavage, groups 3 and 4 received 400mg/kg b.w of EMLL and EPGL each for 7 days plus paracetamol on the 8th day respectively. Catalase (CAT) and superoxide dismutase (SOD) activities and malondialdehyde (MDA) status were assayed for in the kidney, liver and serum. Histopathological examinations of liver and kidney were also carried out. The results showed that EMLL and EPGL exhibited free radical scavenging ability in dose dependent manner towards DPPH, NO, ABTS radicals as well as inhibition of LPO. The results of evaluation of the antioxidant potentials of the extracts while in the plasma showed that they were associated with free radical scavenging activity in vivo. Paracetamol treatment caused significant (p<0.05) decreases in SOD and CAT activities, and marked increase (p<0.05) in MDA levels when compared with the control. However, compared with paracetamol only group, the extracts caused significant (p<0.05) increase in SOD and CAT activities and decreased MDA levels. Histopathological analysis of kidney and liver showed that the extracts were able to offer protection against paracetamol-induced kidney and liver injuries. The extracts therefore have strong antioxidant and cytoprotection abilities.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131030190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecological Mechanism of Dinosaur Extinction","authors":"H. Gu","doi":"10.46545/AIJBLS.V2I1.140","DOIUrl":"https://doi.org/10.46545/AIJBLS.V2I1.140","url":null,"abstract":"To analyze the reasons for the extinction of dinosaurs by applying the elimination methods, to exclude the factors that could not cause the worldwide extinction of the dinosaurs. At last obtain a conclusion that because the Ice Age had come on the Earth and caused the changing of climate that it had been becoming cold and arid from warmth and moist, and caused the phyto-group had been changing, which the Pteridophyte and gymnosperm groups fell off or died out, but the angiosperm groups had been developing and expanding. The characters of photosynthesis of producers of the biosphere had been becoming to the seasonal and regional from the perennial and global, the total of oxygen had reduced sharply in the atmosphere, the density of oxygen had declined, and finally affected the breath of dinosaurs, and led to the extinction of dinosaurs. And as the main producers of biosphere, the pteridophyte and gymnosperm groups had fallen off or died out were the mainly reasons for the creature’s extinction at the later of the Cretaceous period.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117235392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomedical Waste Management in Kandahar City","authors":"Khadem Hussain Saeedi, Abdul Wahid Monib","doi":"10.46545/aijbls.v1i2.124","DOIUrl":"https://doi.org/10.46545/aijbls.v1i2.124","url":null,"abstract":"Biomedical wastes management is one of the most important issues in public health centers and it is a crucial issue for environmental sectors as well. Wrong and inappropriate management treat the life of human beings in Kandahar City. Currently the population of this city has exponentially increased than ever because of the immigration of many people from neighboring provinces. This research was conducted in 15 districts of Kandahar public and private health care centers to identify the current biomedical waste management in Kandahar city. The qualitative and quantitative date was collected through a questionnaire from public and private hospitals, clinics and health care centers. In addition, discarding, segregating, labeling, transporting and disposing system of biomedical waste were observed. The result showed that 65.3% newly hired biomedical waste staff not received training or instruction. Furthermore, the result indicates that 44% generated biomedical wastes are regulated by municipality and color coding is not followed accordingly. Current biomedical waste is not appropriate based on designed international standards and the criteria suggested by world health organization.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130544615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomaterials Electrodes for Degradation of Phenol","authors":"R. Maallah, M. A. Smaini, C. Laghlimi, A. Chtaini","doi":"10.46545/aijbls.v1i2.51","DOIUrl":"https://doi.org/10.46545/aijbls.v1i2.51","url":null,"abstract":"A novel bio electrode containing bacteria immobilized on clay mixed carbon paste electrode (Bactria-clay-CPE) is developed for detection and degradation of the phenolic solutions based on electrochemical techniques such cyclic voltammetry, square wave voltammetry, electroctrochemical impedence spectroscopy. The results obtained showed that bacteria-clay- CPE exhibited excellent electro-catalytic activity towards phenol. The recorded cyclic voltammogram shows that the oxidation of phenol is manifested by the appearance of four oxidation peaks.","PeriodicalId":413331,"journal":{"name":"American International Journal of Biology and Life Sciences","volume":"154 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133914602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}