Clinica e Investigacion en Ginecologia y Obstetricia最新文献

{"title":"Factores asociados al parto pretérmino en el mayor hospital de Honduras: estudio de casos y controles","authors":"J.V. Díaz López ,&nbsp;D.A. Pérez Álvarez ,&nbsp;M.C. Bustillo Urbina ,&nbsp;R.A. Gutierrez-Ramirez","doi":"10.1016/j.gine.2026.101090","DOIUrl":"10.1016/j.gine.2026.101090","url":null,"abstract":"<div><h3>Background</h3><div>Preterm birth, defined as occurring before 37 weeks of gestation, represents a significant challenge in maternal and child health due to the complications it can cause in newborns. Globally, preterm birth rates vary considerably, and its prevalence has increased in recent years, especially in developing countries. In Honduras, the lack of recent studies on this subject hinders a complete understanding of the associated risk factors.</div></div><div><h3>Objective</h3><div>To identify the risk factors associated with preterm birth in pregnant women attended at the Hospital Escuela, during the period from January 2019 to December 2023.</div></div><div><h3>Methods</h3><div>Case-control study, with 369 cases (preterm births) and 369 controls (full-term births). χ² tests, Mann-Whitney U tests, and multivariate logistic regression were used.</div></div><div><h3>Results</h3><div>The findings revealed that low maternal education (aOR: 2.15; 95% CI: 1.40-3.30), rural origin (OR: 0.75; 95% CI: 0.55-0.99), alcohol consumption (aOR: 2.45; 95% CI: 1.25-4.80), previous history of preterm birth (aOR: 2.20; 95% CI: 1.30-3.72), and premature rupture of membranes (aOR: 3.40; 95% CI: 2.10-5.52) were significant independent risk factors. Preterm newborns had significantly lower APGAR scores at the fifth minute (7.63 vs. 8.29; <em>P</em>&lt;.001). Caucasian ethnicity showed an association (OR: 7.23; 95% CI: 1.63-32.0; <em>P</em>=.002), but its low frequency limits generalization.</div></div><div><h3>Conclusions / recommendations</h3><div>It is recommended to implement educational programs for pregnant women with low levels of education and to develop accessible prenatal services in rural areas to reduce the risk of preterm birth.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101090"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146188981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saline-infused hysterography versus 3D transvaginal ultrasound in detecting cesarean scar defect: Diagnostic agreement study","authors":"R.G. Anwar ,&nbsp;M.E. Ahmed ,&nbsp;I.B. Sherif ,&nbsp;A.M. Maaty ,&nbsp;R. Ali ,&nbsp;M.H. Kolaib ,&nbsp;M. Barakat ,&nbsp;W. Elsayed","doi":"10.1016/j.gine.2025.101074","DOIUrl":"10.1016/j.gine.2025.101074","url":null,"abstract":"<div><h3>Background</h3><div>Cesarean section scar defect (CSD), also known as a niche, is a myometrial discontinuity or defect at the site of a previous Cesarean section (CS) incision on the lower segment of the uterus.</div></div><div><h3>Objective</h3><div>Primarily to assess the agreement between three-dimensional transvaginal (3D TVUS) and saline-infused sonohysterography (SIS) for the diagnosis and evaluation of the parameters of CSD. The secondary objective was to evaluate patients’ satisfaction and tolerability with each procedure, in addition to the cost.</div></div><div><h3>Methods</h3><div>We did a prospective agreement study between 3D TVUS and SIS. We included 72 women with a history of cesarean section within the past 6 months to 5 years, and complaining of infertility, dysmenorrhea, lower abdominal/pelvic pain, irregular uterine bleeding, or repeated miscarriages. Recruitment from the ultrasound unit at the Obstetrics and Gynecology department, Ain Shams University, between July 2021 and October 2023. After gaining consent, participants underwent both 3D TVUS and SIS examinations.</div></div><div><h3>Results</h3><div>3D TVUS and SIS showed nearly good agreement regarding the detection of CSD with a kappa (<em>κ</em>) of 0.780 (<em>p</em> <!-->&lt;<!--> <!-->0.001). Regarding the assessment of the parameters, no significant differences were observed between the two modalities regarding depth, length, and width of CSD (<em>p</em> <!-->&gt;<!--> <!-->0.05), but there was a significant difference in the assessment of the volume (<em>p</em> <!-->=<!--> <!-->0.004). 3D TVUS was considerably more expensive (300.00<!--> <!-->±<!--> <!-->0.00 LE) than SIS (231.11<!--> <!-->±<!--> <!-->31.65 LE, <em>p</em> <!-->&lt;<!--> <!-->0.001), but it took less time (5.94<!--> <!-->±<!--> <!-->0.79<!--> <!-->min vs. 14.85<!--> <!-->±<!--> <!-->1.32<!--> <!-->min, <em>p</em> <!-->&lt;<!--> <!-->0.001). With 3D TVUS, all patients (100%) expressed high levels of tolerability and satisfaction, but with SIS, tolerability and satisfaction were 8.3% and 90.3% (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.007, respectively).</div></div><div><h3>Conclusion</h3><div>The comparison between 3D-TVUS and SIS in evaluating cesarean scar defects (CSD) demonstrated a high level of agreement. Moreover, the findings highlight the advantages of 3D-TVUS over SIS in terms of ease of use and patient preference, offering greater satisfaction, better tolerance, and improved time efficiency.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101074"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-centered fertility care perceptions and treatment-related quality of life with infertility","authors":"E. Balkan Kuru ,&nbsp;E. Aslan","doi":"10.1016/j.gine.2025.101087","DOIUrl":"10.1016/j.gine.2025.101087","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite patient-centered care has positive effects on treatment and increases the quality of care, healthcare workers do not emphasize patient-centered care enough and this situation may negatively affect the treatment-related QoL. This study aimed to investigate the perceptions of infertile women regarding patient-centered fertility care and treatment-related quality of life.</div></div><div><h3>Methods</h3><div>Descriptive Information Form, Patient-Centered Fertility Care Questionnaire for Infertile Women, and FertiQol Treatment Module were used to collect data from 160 infertile women in Türkiye between July and October 2020.</div></div><div><h3>Results</h3><div>The mean patient-centered care perception score was 7.49<!--> <!-->±<!--> <!-->1.91, and participants received a mean score of 65.96<!--> <!-->±<!--> <!-->15.65 on FertiQol Treatment Module. A statistically significant positive correlation existed between patient-centered fertility care perception and the FertiQol Treatment Module scores. Nearly half of the women received sufficient attention and support from the nurses, and more than half of the women stated that the nurses were considerate toward them. However, 48.8% of the women reported were not informed about the side effects of the drugs, and 36.9% of them were not informed about the injection methods.</div></div><div><h3>Conclusion</h3><div>The components of patient-centered fertility care were included in fertility treatment. Patient-centered fertility care approach has been found to correlate to the treatment-related QoL. But due to the lack of received information about the fertility treatments, it is suggested that healthcare professionals in fertility clinics should provide therapeutic education to improve the patient-centered care perceptions and treatment related QoL of the infertile individuals.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101087"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse adenomyosis and bilateral ovarian adhesions on ultrasound are associated with impaired quality of life in patients with deep infiltrating endometriosis","authors":"A. Ruano ,&nbsp;J. Munrós ,&nbsp;L. Mañalich ,&nbsp;S. Monreal ,&nbsp;D. Guerrero ,&nbsp;E. Suárez","doi":"10.1016/j.gine.2025.101072","DOIUrl":"10.1016/j.gine.2025.101072","url":null,"abstract":"<div><h3>Introduction</h3><div>The association between ultrasonographic features and symptom burden in patients with deep infiltrating endometriosis (DIE) remains unclear. This study aimed to evaluate whether specific transvaginal ultrasound (TVUS) markers are associated with health-related quality of life (HRQoL) in women with DIE.</div></div><div><h3>Methods</h3><div>We conducted a prospective observational study including 114 patients with confirmed DIE, evaluated by both magnetic resonance and TVUS. HRQoL was assessed using the Endometriosis Health Profile-5 (EHP-5) questionnaire. TVUS markers included diffuse adenomyosis, bilateral ovarian adhesions, and large DIE lesions. Bivariate and multivariate linear regression analyses were performed to identify ultrasound features independently associated with HRQoL.</div></div><div><h3>Results</h3><div>Diffuse adenomyosis and bilateral ovarian adhesions were significantly associated with higher EHP-5 scores in both bivariate and multivariate analyses. Patients with diffuse adenomyosis had a mean EHP-5 score of 47.3<!--> <!-->±<!--> <!-->17.9 versus 36.2<!--> <!-->±<!--> <!-->21.5 in those without (mean difference: 11.09; <em>p</em> <!-->=<!--> <!-->0.005). Bilateral ovarian adhesions were associated with scores of 45.4<!--> <!-->±<!--> <!-->20.1 versus 34.1<!--> <!-->±<!--> <!-->20.2 (mean difference: 11.38; <em>p</em> <!-->=<!--> <!-->0.006). In the adjusted model, both markers remained independently associated with impaired HRQoL. The presence of large (&gt;3<!--> <!-->cm) posterior DIE lesions showed no significant association. The model's explanatory power was modest (<em>R</em>² <!-->=<!--> <!-->0.112).</div></div><div><h3>Conclusion</h3><div>Diffuse adenomyosis and bilateral ovarian adhesions are independent ultrasonographic predictors of impaired HRQoL in patients with DIE. Identifying these features during routine TVUS may help guide individualized management strategies.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101072"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Escalas de evaluación de la actividad lúpica en el embarazo","authors":"D. Guavita-Navarro ,&nbsp;L.C. Guavita ,&nbsp;V. Barbosa-Prieto ,&nbsp;C. Sanmiguel-Reyes","doi":"10.1016/j.gine.2025.101054","DOIUrl":"10.1016/j.gine.2025.101054","url":null,"abstract":"<div><div>Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that frequently experiences flares during pregnancy due to the physiological and immunological changes characteristic of this period. These alterations can present as lupus activity or obstetric complications, particularly hypertensive disorders, necessitating precise clinical assessment and multidisciplinary management to minimize maternal and fetal risks. Given the importance of accurately identifying disease activity during pregnancy and the postpartum period, this review examines the main available indices for evaluating lupus activity in pregnant patients.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101054"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptación de un sistema de presión negativa con succión central de bajo costo para el tratamiento de heridas ginecoobstétricas infectadas. Un estudio de cohorte retrospectivo","authors":"Carlos Dragonas-Romo ,&nbsp;Silvia Caballero-Delgado ,&nbsp;Jorge Luis Rodríguez-Sánchez ,&nbsp;José Juan Quilantán-Cabrera ,&nbsp;Karla Fabiola Rodríguez-Gómez ,&nbsp;Luis Enrique Colunga-Lozano","doi":"10.1016/j.gine.2025.101064","DOIUrl":"10.1016/j.gine.2025.101064","url":null,"abstract":"<div><h3>Background</h3><div>The objective is to describe a technique for placing a negative pressure wound therapy system using central suction as a treatment for infected surgical wounds in low-resource settings.</div></div><div><h3>Methods</h3><div>A retrospective cohort study was conducted at the General Hospital of Zapopan from November 2021 to May 2023. We included patients from the Gynecology and Obstetrics Department with infected and dehiscence surgical wound who consented underwent placement of a central suction system. Surgical time, intraoperative bleeding, complications, morbidity, and mortality were analyzed. We evaluated the patients in the preoperative, immediate postoperative, and 3-month follow-up.</div></div><div><h3>Results</h3><div>Ten patients were included, comprising 8 post-cesarean section patients, one post-hysterectomy patient, and one patient with Fournier's gangrene. The mean age was 29.91 years (±<!--> <!-->12.97), with 5 patients having comorbidities. All patients with infected surgical wounds had wound dehiscence. Variations in the results of wound secretion cultures were found with the following pathogens: <em>Staphylococcus lugdunensis, Staphylococcus epidermidis, Streptococcus gallolyticus</em> and <em>Klebsiella oxytoca,</em> indicating no particular etiological agent. Length of hospital stay depended on the case, wound extent and depth, and the number of required changes.</div></div><div><h3>Conclusion</h3><div>Our technique is a cost-effective alternative for managing surgical wounds with favorable outcomes, suitable for replication in low-resource hospitals. However, further studies with a larger number of patients are needed.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101064"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144893562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenocarcinoma de células claras primario del cuello uterino sin exposición intrauterina al dietilestilbestrol en una adolescente de 15 años. Un caso clinicopatológico","authors":"R. Sarabia Ochoa ,&nbsp;J.P. García de la Torre ,&nbsp;A. Canosa Fernández","doi":"10.1016/j.gine.2025.101070","DOIUrl":"10.1016/j.gine.2025.101070","url":null,"abstract":"<div><h3>Introduction</h3><div>Clear cell adenocarcinoma of the cervix is a rare histological variant that is usually associated with intrauterine exposure to diethylstilbestrol (DES).</div></div><div><h3>Main symptoms and/or clinical findings</h3><div>A 15-year-old girl, virgin, with vaginal bleeding and leucorrhea. There was no history of exposure to diethylstilbestrol. Gynecological examination revealed a 7<!--> <!-->cm, solid, irregular, polypoid mass in the vagina, based on the anterior lip of the cervix.</div></div><div><h3>Main diagnoses, therapeutic interventions, and results</h3><div>The tumor was excised in fragments by colposcopy. Histologically it corresponded to a malignant epithelial neoplasm with a tubulocystic pattern, with papillary and solid areas. Composed of clear or hobnail cells, atypical vesicular nuclei and frequent nucleoli. Psammomatous microcalcifications and foci of tumor necrosis were present. Immunoreactivity for PAX8, CKAE1/3AE, EMA, CA-125, CK7, and Napsin-A was present. The diagnosis was clear cell adenocarcinoma.</div><div>The patient was treated with radical hysterectomy and is disease-free three years later.</div></div><div><h3>Conclusion</h3><div>Clear cell adenocarcinoma of the cervix is a rare tumor lacking clear guidelines for effective treatment. The clinical manifestations are basically the same as those of cervical squamous cell carcinoma, and in young patients, they can be confused with dysfunctional uterine bleeding, requiring a correct differential diagnosis. Our patient received primary treatment with colposcopic electrosurgical excision biopsy, followed by radical hysterectomy without chemotherapy or radiation therapy. This could be a new treatment approach for early-stage patients given the positive results observed.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101070"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report of spontaneous hemoperitoneum secondary to uterine myomatosis and adenomyosis","authors":"J.C. Ramírez ,&nbsp;K. Cepeda ,&nbsp;F. Carmona","doi":"10.1016/j.gine.2025.101066","DOIUrl":"10.1016/j.gine.2025.101066","url":null,"abstract":"<div><h3>Introduction</h3><div>Myomatosis and uterine adenomyosis are the most common benign uterine pathologies suffered by women of reproductive age and the symptoms they produce are mainly abnormal vaginal bleeding, dysmenorrhea and pelvic pain, but they are rarely associated with spontaneous peritoneal bleeding. The existence of this entity and its etiology is little known in the literature, limited to case reports, generating a difficulty in diagnosis. The objective of this article is to report an infrequent case of spontaneous hemoperitoneum secondary to uterine myomatosis and adenomyosis.</div></div><div><h3>Main symptoms</h3><div>Prior informed consent and certification from the institution's ethics committee. This is a 50-year-old Colombian patient, in a state of symptomatic perimenopause with hormone replacement therapy, who came to the emergency department with a history of pain in the lower abdomen of three days of severe intensity, only associated with diarrhea.</div></div><div><h3>Main diagnoses</h3><div>Abdominal computed tomography and transvaginal ultrasound diagnosed hemoperitoneum associated with a probable left adnexal mass, suggestive of a ruptured hemorrhagic cyst.</div></div><div><h3>Therapeutic interventions and results</h3><div>Exploratory laparoscopy was performed and identify hemoperitoneum secondary to a highly vascularized subserosal fibroid with bleeding from its base, hypervascularized uterus, without obvious ovarian pathology, associated with multiple adhesions between the fibroid, uterine tube and ipsilateral ovary. Due to the patient's age and continuous uncontrolled bleeding, it was decided to perform a total hysterectomy plus unilateral left salpingo-oferectomy.</div></div><div><h3>Conclusion</h3><div>This case demonstrates that, although extremely rare, uterine fibroids (still coexisting with adenomyosis) can cause spontaneous hemoperitoneum. It is essential to consider this diagnosis within the acute gynecological abdomen, since timely recognition and treatment improve the prognosis.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101066"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144988045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relación entre la lactancia materna y las disfunciones sexuales en el posparto. Una revisión sistemática","authors":"A. Rodríguez-Alonso ,&nbsp;I. Da Cuña-Carrera ,&nbsp;A. Alonso-Calvete ,&nbsp;L. Núñez-Remiseiro ,&nbsp;M. Fernández-Paz","doi":"10.1016/j.gine.2025.101067","DOIUrl":"10.1016/j.gine.2025.101067","url":null,"abstract":"<div><div>Breastfeeding is defined as the act of transferring milk between mother and child, constituting the ideal and physiological food for neonates. Female sexual dysfunction is established as a disorder of sexual desire, arousal, orgasm and/or sexual pain. The objective of this work is to review and analyze the existing literature to find out if there is a relationship between breastfeeding and the presence of sexual dysfunctions in the postpartum. A bibliographic search was carried out between the months of November and December 2023 in the PubMed, Web of Science (WOS), Scopus, Cochrane Library and Cinahl databases. The descriptors from the Medical Subject Headings (MeSH) thesaurus “Lactation”, “Breast Feeding”, “Postpartum Period”, “Sexual Dysfunction, Physiological” and “Sexual Dysfunctions, Psychological” were used. Articles published in English or Spanish that met the criteria were included. the objective of this review. Of the 123 articles identified, only 9 met the eligibility criteria and were included in the review. Breastfeeding seems to have a relationship with the presence of female sexual dysfunctions in the postpartum, with lower scores being observed in the sexual function questionnaires in lactating women compared to those of non-lactating women. However, it seems difficult to discern between sexual dysfunctions due to breastfeeding and those due to postpartum.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101067"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145264980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Síndrome de hiperestimulación ovárica grave con elevación transitoria de troponina I: a propósito de un caso","authors":"I. Agustí ,&nbsp;G. Altinier ,&nbsp;G. Casals","doi":"10.1016/j.gine.2025.101068","DOIUrl":"10.1016/j.gine.2025.101068","url":null,"abstract":"<div><h3>Introduction</h3><div>Ovarian hyperstimulation syndrome (OHSS) is a potentially serious complication of controlled ovarian stimulation, with risk of multi-organ involvement. We present a clinical case of severe OHSS that initially manifested with symptoms suggestive of cardiac involvement and transient troponin elevation, in which cardiac pathology was ultimately ruled out.</div></div><div><h3>Main symptoms and/or clinical findings</h3><div>A 26-year-old woman, with no cardiovascular history, presented with abdominal distension, nausea, and acute epigastric pain after follicular puncture in the context of controlled ovarian stimulation for egg donation.</div></div><div><h3>Main diagnoses, therapeutic interventions, and outcomes</h3><div>Severe OHSS was diagnosed with tense ascites, hemoconcentration, altered renal profile, and marked elevation of troponin I (1098 ng/L) and D-dimer. Given the suspicion of myocardial ischemia, cardiological studies were performed, ruling out cardiac pathology. Medical treatment with albumin and diuretics was initiated, with clinical resolution without the need for paracentesis. The patient was discharged after four days, with normalization of laboratory and echocardiographic parameters.</div></div><div><h3>Conclusion</h3><div>Severe OHSS may present with clinical signs and biomarkers suggestive of cardiac disease. This finding highlights the importance of considering troponin elevation in OHSS within the context of hemodynamic and/or endothelial dysfunction, rather than as a specific marker of myocardial ischemia. This is especially relevant in severe multi-organ clinical presentations where differential diagnosis is crucial.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101068"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145332345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}