Clinica e Investigacion en Ginecologia y Obstetricia最新文献

{"title":"Síntomas vasomotores y alteraciones del sueño y anímicas en el climaterio: nuevas perspectivas con las terapias dirigidas a los receptores de neuroquininas","authors":"M.J. Cancelo-Hidalgo ,&nbsp;P.J. Coronado-Martín ,&nbsp;M. Herrero-Conde ,&nbsp;A. Martínez-Aspas ,&nbsp;M.Á. Martínez-Maestre ,&nbsp;J. Perelló-Capo ,&nbsp;R. Sánchez-Borrego","doi":"10.1016/j.gine.2026.101089","DOIUrl":"10.1016/j.gine.2026.101089","url":null,"abstract":"<div><div>The transition to menopause is a process of variable duration associated with various endocrine, physical, and psychological changes and irregular menstrual cycles. During this period, up to 85% of women experience climacteric symptoms, of which vasomotor symptoms (VMS) and sleep and mood disturbances (depression or anxiety) are among the most frequent and have the greatest impact on women's quality of life. Although VMS can impact sleep quality and mood, these symptoms can occur independently. This review addresses the epidemiology, relevance, and etiopathogenesis of VMS, sleep and mood disorders, and the current treatments (hormonal and other pharmacological and non-pharmacological options) available to relieve these cardinal climacteric symptoms. Advances in the understanding of the etiopathogenesis of these symptoms and, in particular, the role of neurotransmitters neurokinin B (NKB)—involved in several reproductive processes—and substance P—related to sleep and mood regulation—, and their receptors (neurokinin 3 receptor [NK-3R] and neurokinin 1 receptor [NK-1R]), have prompted the development of neurokinin receptor-targeted therapies for the treatment of menopause. These include fezolinetant (NK-3R antagonist) and elinzanetant (NK-3R and NK-1R antagonist). We update the available evidence on the improvement of these climacteric symptoms with neurokinin receptor-targeted therapies.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 2","pages":"Article 101089"},"PeriodicalIF":0.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146193296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of adjuvant extrafascial hysterectomy after chemoradiotherapy and the prognostic relevance of residual disease in locally advanced cervical cancer","authors":"T.A. de Sousa ,&nbsp;M.J.A. Nascimento ,&nbsp;S.M. Medeiros ,&nbsp;R.O. Macedo ,&nbsp;N.D.M. Dias ,&nbsp;M.C.M. Novais ,&nbsp;N.M.P.V. Barreto ,&nbsp;P.H. Zanvettor","doi":"10.1016/j.gine.2026.101108","DOIUrl":"10.1016/j.gine.2026.101108","url":null,"abstract":"<div><h3>Background</h3><div>The impact of adjuvant extrafascial hysterectomy (AEH) after chemoradiotherapy (CRT) in locally advanced cervical cancer (LACC) remains unclear.</div></div><div><h3>Objective</h3><div>To investigate the association between AEH after CRT and oncologic outcomes in patients with LACC without clinical evidence of persistent disease, with emphasis on the frequency and prognostic relevance of residual disease (RD) among operated patients.</div></div><div><h3>Methods</h3><div>This retrospective cohort study analyzed Brazilian patients with LACC treated with CRT at a tertiary center. After CRT, patients were divided into standard treatment (ST), consisting of surveillance with rescue surgery when persistent or recurrent disease was suspected or confirmed, and AEH, consisting of type A hysterectomy in patients without clinical evidence of persistent disease.</div></div><div><h3>Results</h3><div>A total of 181 patients were included: 137 (75.7%) in the ST group and 44 (24.3%) in the AEH group. RD was found in 52 operated patients (55.3%), including 18/44 (40.9%) in the AEH group and 34/50 (68.0%) in the ST group. In adenocarcinomas, RD remained high (37.5%) even after complete clinical response. Recurrence occurred in 72 patients (39.8%). Patients with RD had higher recurrence and distant metastasis rates. Crude mortality was lower in the AEH group (25.0% vs. 41.6%; <em>p</em> <!-->=<!--> <!-->0.048). Among operated patients who died, 90.3% had RD.</div></div><div><h3>Conclusion</h3><div>RD was the main prognostic finding, being strongly associated with recurrence and death. Although lower crude mortality was observed in the AEH group, this finding should be interpreted cautiously given the retrospective design and baseline imbalance between groups.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 2","pages":"Article 101108"},"PeriodicalIF":0.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147710126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnóstico prenatal de síndrome de Beckwith-Wiedemann en un feto con nefromegalia bilateral: a propósito de un caso","authors":"M. Tarbal Roquer ,&nbsp;N. Capdevila Atienza ,&nbsp;C. Lesmes Heredia ,&nbsp;N. Baena Díez ,&nbsp;M. Comas Rovira","doi":"10.1016/j.gine.2025.101088","DOIUrl":"10.1016/j.gine.2025.101088","url":null,"abstract":"<div><h3>Introduction</h3><div>Beckwith-Wiedemann Syndrome (BWS) is a congenital disorder characterized by excessive growth and a range of clinical manifestations, including macroglossia, macrosomia, polyhydramnios, visceromegaly, and abdominal wall defects, as well as an elevated risk of developing embryonic tumours, such as Wilms tumour. Most cases are sporadic, although about 15% are inherited. Prenatal diagnosis is a challenge due to its wide phenotypic variability.</div></div><div><h3>Main symptoms and clinical findings</h3><div>This case presents a prenatal and genetic diagnosis of BWS following the detection of bilateral nephromegaly and macroglossia on the second-trimester ultrasound in a 32-year-old pregnant woman, which led to suspicion of BWS.</div></div><div><h3>Main diagnosis</h3><div>Genetic confirmation was obtained through the analysis of methylation in the IC1 region of chromosome 11p15.5.</div></div><div><h3>Therapeutic intervention and results</h3><div>The pregnant woman developed severe preeclampsia at 37 weeks, and the pregnancy was terminated. The newborn's physical examination revealed macroglossia without airway involvement and macrosomia. Postnatal management required treatment for neonatal hypoglycemia, medical and surgical treatment for macroglossia, and subsequent early tumour diagnosis follow-up.</div></div><div><h3>Conclusion</h3><div>This case highlights the importance of prenatal diagnostic suspicion and genetic studies in the early identification of BWS, enabling multidisciplinary follow-up during pregnancy in a tertiary care centre and appropriate postnatal management to prevent complications associated with these cases.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101088"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Actualización de los efectos de la fisioterapia en el manejo de prolapsos de órganos pélvicos. Una revisión sistemática","authors":"D. Rivadulla-Lorenzo ,&nbsp;I. Da Cuña-Carrera ,&nbsp;A. Alonso-Calvete ,&nbsp;D. Tomé-Lage ,&nbsp;M. López-Pais","doi":"10.1016/j.gine.2025.101086","DOIUrl":"10.1016/j.gine.2025.101086","url":null,"abstract":"<div><h3>Background</h3><div>Pelvic organ prolapse is a common dysfunction among adult women worldwide, characterized by the pathological displacement of the uterus, bladder, or other organs from their anatomical position. This condition can lead to urinary, bowel, or sexual symptoms. Physiotherapy, as a conservative treatment, offers significant benefits in alleviating these symptoms. This review aims to analyze the most recent scientific evidence to evaluate the effectiveness of the latest physiotherapy treatments in managing prolapse.</div></div><div><h3>Materials and methods</h3><div>A literature search was conducted in January 2025 across the databases PubMed®, Web of Science™, Scopus®, PEDro, SciELO, and CINAHL®. The descriptors «Pelvic Organ Prolapse» and «Physical Therapy Modalities» were used. Randomized controlled trials published in the last five years in English or Spanish were included.</div></div><div><h3>Results</h3><div>A total of 466 results were obtained, of which 10 were selected after meeting the inclusion criteria. The articles under review developed different physiotherapy interventions, among which the favorable effects of pelvic floor muscle training in reducing the degree of prolapse and improving quality of life and sexuality stand out.</div></div><div><h3>Conclusion</h3><div>Physiotherapy appears to have beneficial effects in improving quality of life, prolapse severity, and pelvic floor muscle strength.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101086"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tokophobia: A narrative review of etiology, prevalence, and treatment options","authors":"L. Esmalian Khamseh ,&nbsp;J. Jomeen ,&nbsp;R. Cousins ,&nbsp;M. Aruguete ,&nbsp;V. Sharma","doi":"10.1016/j.gine.2025.101073","DOIUrl":"10.1016/j.gine.2025.101073","url":null,"abstract":"<div><div>Tokophobia, the intense fear of childbirth, is increasingly recognized as a significant global health concern with serious implications for women's mental well-being and reproductive decisions. This narrative review explores its worldwide incidence and prevalence, revealing notable variations across regions—moderate to high rates are reported in Asia, Australia, the Middle East, and Africa, while lower rates are observed in European countries. Tokophobia is associated with adverse mental health outcomes such as anxiety, depression, and post-traumatic stress disorder, and it also influences reproductive behavior, including reduced fertility and increased preference for elective cesarean sections. A comprehensive literature search was conducted using databases such as PubMed, Web of Science, and Google Scholar, focusing on studies published between 2013 and 2023. The findings highlight the urgent need for early detection and targeted interventions to mitigate the psychological and reproductive consequences of tokophobia. Greater awareness and research into its complex interplay with maternal mental health are essential to inform clinical practice and public health strategies.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101073"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factores asociados al parto pretérmino en el mayor hospital de Honduras: estudio de casos y controles","authors":"J.V. Díaz López ,&nbsp;D.A. Pérez Álvarez ,&nbsp;M.C. Bustillo Urbina ,&nbsp;R.A. Gutierrez-Ramirez","doi":"10.1016/j.gine.2026.101090","DOIUrl":"10.1016/j.gine.2026.101090","url":null,"abstract":"<div><h3>Background</h3><div>Preterm birth, defined as occurring before 37 weeks of gestation, represents a significant challenge in maternal and child health due to the complications it can cause in newborns. Globally, preterm birth rates vary considerably, and its prevalence has increased in recent years, especially in developing countries. In Honduras, the lack of recent studies on this subject hinders a complete understanding of the associated risk factors.</div></div><div><h3>Objective</h3><div>To identify the risk factors associated with preterm birth in pregnant women attended at the Hospital Escuela, during the period from January 2019 to December 2023.</div></div><div><h3>Methods</h3><div>Case-control study, with 369 cases (preterm births) and 369 controls (full-term births). χ² tests, Mann-Whitney U tests, and multivariate logistic regression were used.</div></div><div><h3>Results</h3><div>The findings revealed that low maternal education (aOR: 2.15; 95% CI: 1.40-3.30), rural origin (OR: 0.75; 95% CI: 0.55-0.99), alcohol consumption (aOR: 2.45; 95% CI: 1.25-4.80), previous history of preterm birth (aOR: 2.20; 95% CI: 1.30-3.72), and premature rupture of membranes (aOR: 3.40; 95% CI: 2.10-5.52) were significant independent risk factors. Preterm newborns had significantly lower APGAR scores at the fifth minute (7.63 vs. 8.29; <em>P</em>&lt;.001). Caucasian ethnicity showed an association (OR: 7.23; 95% CI: 1.63-32.0; <em>P</em>=.002), but its low frequency limits generalization.</div></div><div><h3>Conclusions / recommendations</h3><div>It is recommended to implement educational programs for pregnant women with low levels of education and to develop accessible prenatal services in rural areas to reduce the risk of preterm birth.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101090"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146188981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saline-infused hysterography versus 3D transvaginal ultrasound in detecting cesarean scar defect: Diagnostic agreement study","authors":"R.G. Anwar ,&nbsp;M.E. Ahmed ,&nbsp;I.B. Sherif ,&nbsp;A.M. Maaty ,&nbsp;R. Ali ,&nbsp;M.H. Kolaib ,&nbsp;M. Barakat ,&nbsp;W. Elsayed","doi":"10.1016/j.gine.2025.101074","DOIUrl":"10.1016/j.gine.2025.101074","url":null,"abstract":"<div><h3>Background</h3><div>Cesarean section scar defect (CSD), also known as a niche, is a myometrial discontinuity or defect at the site of a previous Cesarean section (CS) incision on the lower segment of the uterus.</div></div><div><h3>Objective</h3><div>Primarily to assess the agreement between three-dimensional transvaginal (3D TVUS) and saline-infused sonohysterography (SIS) for the diagnosis and evaluation of the parameters of CSD. The secondary objective was to evaluate patients’ satisfaction and tolerability with each procedure, in addition to the cost.</div></div><div><h3>Methods</h3><div>We did a prospective agreement study between 3D TVUS and SIS. We included 72 women with a history of cesarean section within the past 6 months to 5 years, and complaining of infertility, dysmenorrhea, lower abdominal/pelvic pain, irregular uterine bleeding, or repeated miscarriages. Recruitment from the ultrasound unit at the Obstetrics and Gynecology department, Ain Shams University, between July 2021 and October 2023. After gaining consent, participants underwent both 3D TVUS and SIS examinations.</div></div><div><h3>Results</h3><div>3D TVUS and SIS showed nearly good agreement regarding the detection of CSD with a kappa (<em>κ</em>) of 0.780 (<em>p</em> <!-->&lt;<!--> <!-->0.001). Regarding the assessment of the parameters, no significant differences were observed between the two modalities regarding depth, length, and width of CSD (<em>p</em> <!-->&gt;<!--> <!-->0.05), but there was a significant difference in the assessment of the volume (<em>p</em> <!-->=<!--> <!-->0.004). 3D TVUS was considerably more expensive (300.00<!--> <!-->±<!--> <!-->0.00 LE) than SIS (231.11<!--> <!-->±<!--> <!-->31.65 LE, <em>p</em> <!-->&lt;<!--> <!-->0.001), but it took less time (5.94<!--> <!-->±<!--> <!-->0.79<!--> <!-->min vs. 14.85<!--> <!-->±<!--> <!-->1.32<!--> <!-->min, <em>p</em> <!-->&lt;<!--> <!-->0.001). With 3D TVUS, all patients (100%) expressed high levels of tolerability and satisfaction, but with SIS, tolerability and satisfaction were 8.3% and 90.3% (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.007, respectively).</div></div><div><h3>Conclusion</h3><div>The comparison between 3D-TVUS and SIS in evaluating cesarean scar defects (CSD) demonstrated a high level of agreement. Moreover, the findings highlight the advantages of 3D-TVUS over SIS in terms of ease of use and patient preference, offering greater satisfaction, better tolerance, and improved time efficiency.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101074"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-centered fertility care perceptions and treatment-related quality of life with infertility","authors":"E. Balkan Kuru ,&nbsp;E. Aslan","doi":"10.1016/j.gine.2025.101087","DOIUrl":"10.1016/j.gine.2025.101087","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite patient-centered care has positive effects on treatment and increases the quality of care, healthcare workers do not emphasize patient-centered care enough and this situation may negatively affect the treatment-related QoL. This study aimed to investigate the perceptions of infertile women regarding patient-centered fertility care and treatment-related quality of life.</div></div><div><h3>Methods</h3><div>Descriptive Information Form, Patient-Centered Fertility Care Questionnaire for Infertile Women, and FertiQol Treatment Module were used to collect data from 160 infertile women in Türkiye between July and October 2020.</div></div><div><h3>Results</h3><div>The mean patient-centered care perception score was 7.49<!--> <!-->±<!--> <!-->1.91, and participants received a mean score of 65.96<!--> <!-->±<!--> <!-->15.65 on FertiQol Treatment Module. A statistically significant positive correlation existed between patient-centered fertility care perception and the FertiQol Treatment Module scores. Nearly half of the women received sufficient attention and support from the nurses, and more than half of the women stated that the nurses were considerate toward them. However, 48.8% of the women reported were not informed about the side effects of the drugs, and 36.9% of them were not informed about the injection methods.</div></div><div><h3>Conclusion</h3><div>The components of patient-centered fertility care were included in fertility treatment. Patient-centered fertility care approach has been found to correlate to the treatment-related QoL. But due to the lack of received information about the fertility treatments, it is suggested that healthcare professionals in fertility clinics should provide therapeutic education to improve the patient-centered care perceptions and treatment related QoL of the infertile individuals.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101087"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse adenomyosis and bilateral ovarian adhesions on ultrasound are associated with impaired quality of life in patients with deep infiltrating endometriosis","authors":"A. Ruano ,&nbsp;J. Munrós ,&nbsp;L. Mañalich ,&nbsp;S. Monreal ,&nbsp;D. Guerrero ,&nbsp;E. Suárez","doi":"10.1016/j.gine.2025.101072","DOIUrl":"10.1016/j.gine.2025.101072","url":null,"abstract":"<div><h3>Introduction</h3><div>The association between ultrasonographic features and symptom burden in patients with deep infiltrating endometriosis (DIE) remains unclear. This study aimed to evaluate whether specific transvaginal ultrasound (TVUS) markers are associated with health-related quality of life (HRQoL) in women with DIE.</div></div><div><h3>Methods</h3><div>We conducted a prospective observational study including 114 patients with confirmed DIE, evaluated by both magnetic resonance and TVUS. HRQoL was assessed using the Endometriosis Health Profile-5 (EHP-5) questionnaire. TVUS markers included diffuse adenomyosis, bilateral ovarian adhesions, and large DIE lesions. Bivariate and multivariate linear regression analyses were performed to identify ultrasound features independently associated with HRQoL.</div></div><div><h3>Results</h3><div>Diffuse adenomyosis and bilateral ovarian adhesions were significantly associated with higher EHP-5 scores in both bivariate and multivariate analyses. Patients with diffuse adenomyosis had a mean EHP-5 score of 47.3<!--> <!-->±<!--> <!-->17.9 versus 36.2<!--> <!-->±<!--> <!-->21.5 in those without (mean difference: 11.09; <em>p</em> <!-->=<!--> <!-->0.005). Bilateral ovarian adhesions were associated with scores of 45.4<!--> <!-->±<!--> <!-->20.1 versus 34.1<!--> <!-->±<!--> <!-->20.2 (mean difference: 11.38; <em>p</em> <!-->=<!--> <!-->0.006). In the adjusted model, both markers remained independently associated with impaired HRQoL. The presence of large (&gt;3<!--> <!-->cm) posterior DIE lesions showed no significant association. The model's explanatory power was modest (<em>R</em>² <!-->=<!--> <!-->0.112).</div></div><div><h3>Conclusion</h3><div>Diffuse adenomyosis and bilateral ovarian adhesions are independent ultrasonographic predictors of impaired HRQoL in patients with DIE. Identifying these features during routine TVUS may help guide individualized management strategies.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"53 1","pages":"Article 101072"},"PeriodicalIF":0.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Escalas de evaluación de la actividad lúpica en el embarazo","authors":"D. Guavita-Navarro ,&nbsp;L.C. Guavita ,&nbsp;V. Barbosa-Prieto ,&nbsp;C. Sanmiguel-Reyes","doi":"10.1016/j.gine.2025.101054","DOIUrl":"10.1016/j.gine.2025.101054","url":null,"abstract":"<div><div>Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that frequently experiences flares during pregnancy due to the physiological and immunological changes characteristic of this period. These alterations can present as lupus activity or obstetric complications, particularly hypertensive disorders, necessitating precise clinical assessment and multidisciplinary management to minimize maternal and fetal risks. Given the importance of accurately identifying disease activity during pregnancy and the postpartum period, this review examines the main available indices for evaluating lupus activity in pregnant patients.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101054"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}